Ligand: DYK

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 4D2SA
DFGin None 1 50.0% 4D2RA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
OTHER TTK TTK_HUMAN 4D2SA P33981 513 793 857.0 DYK:1794 Type1 Inactive DFGin 4.273 14.767 ABAminus -95.21, -44.96 -135.94, 172.0 -115.3, 6.49 305.25, 149.5 77.48, -1.71 out-out out 10.71 Saltbr-out 6.614 HRD-in -50.94, -45.09 68.46, -25.84 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 127.79 APE8-rot-out 187.01 APE67-dihe-in -52.43, -42.93 -100.42, -1.9 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.5 0.181 0.221 A 284 249 32 0 0 17 [[525, 791]] 1.0 4d2s OTHER_TTK_HUMAN CAMK 5.8e-54 189.0 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TYR IGF1R IGF1R_HUMAN 4D2RA P08069 985 1286 1367.0 DYK:2288 Type1 Inactive DFGin 6.17 16.203 None -69.68, 163.13 -53.49, 135.63 -66.9, 144.51 304.26, 163.38 61.31, 29.83 out-out out 10.267 Saltbr-out 6.647 HRD-in -70.04, -49.33 73.87, -13.98 out-out-in SNCooi out-in ActLoopNT-out 17.489 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -74.92, 112.08 APE9-dihe-in -125.82, 147.19 APE8-dihe-in -85.98, 69.81 APE8-rot-na 32.75 APE67-dihe-in -73.08, -8.74 -50.8, -35.19 APE12-dist-na 21.901 APE11-dist-na 17.034 APE10-dist-na 13.417 APE9-dist-in 7.156 None None None XRAY 2.1 0.181 0.221 A 302 300 2 0 0 2 [[999, 1268]] 1.0 4d2r TYR_IGF1R_HUMAN TYR 1.8e-95 325.1 1 260 260 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor

Ligand: DYK

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 4D2SA
DFGin None 1 50.0% 4D2RA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
OTHER TTK TTK_HUMAN 4D2SA P33981 513 793 857.0 DYK:1794 Type1 Inactive DFGin 4.273 14.767 ABAminus -95.21, -44.96 -135.94, 172.0 -115.3, 6.49 305.25, 149.5 77.48, -1.71 out-out out 10.71 Saltbr-out 6.614 HRD-in -50.94, -45.09 68.46, -25.84 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 127.79 APE8-rot-out 187.01 APE67-dihe-in -52.43, -42.93 -100.42, -1.9 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.5 0.181 0.221 A 284 249 32 0 0 17 [[525, 791]] 1.0 4d2s Homo sapiens OTHER_TTK_HUMAN CAMK 5.8e-54 189.0 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TYR IGF1R IGF1R_HUMAN 4D2RA P08069 985 1286 1367.0 DYK:2288 Type1 Inactive DFGin 6.17 16.203 None -69.68, 163.13 -53.49, 135.63 -66.9, 144.51 304.26, 163.38 61.31, 29.83 out-out out 10.267 Saltbr-out 6.647 HRD-in -70.04, -49.33 73.87, -13.98 out-out-in SNCooi out-in ActLoopNT-out 17.489 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -74.92, 112.08 APE9-dihe-in -125.82, 147.19 APE8-dihe-in -85.98, 69.81 APE8-rot-na 32.75 APE67-dihe-in -73.08, -8.74 -50.8, -35.19 APE12-dist-na 21.901 APE11-dist-na 17.034 APE10-dist-na 13.417 APE9-dist-in 7.156 None None None XRAY 2.1 0.181 0.221 A 302 300 2 0 0 2 [[999, 1268]] 1.0 4d2r Homo sapiens TYR_IGF1R_HUMAN TYR 1.8e-95 325.1 1 260 260 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor

Ligand: DYK

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name