Ligand: DYK

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 4D2SA
DFGin None 1 50.0% 4D2RA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
OTHER TTK TTK_HUMAN 4D2SA P33981 513 793 857.0 DYK:1794 Type1 Inactive DFGin 4.2732 14.7666 ABAminus -95.21, -44.96 -135.94, 172.0 -115.3, 6.49 305.25, 149.5 77.48, -1.71 out-out out 10.7098 Saltbr-out 6.6144 HRD-in -50.94, -45.09 68.46, -25.84 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 127.79 APE8-rot-out 187.01 APE67-dihe-in -52.43, -42.93 -100.42, -1.9 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.5 0.181 0.221 A 284.0 249.0 32 30 13 17 [[525, 791]] 1.0 4d2s OTHER_TTK_HUMAN CAMK 5.8e-54 189.0 1.0 256.0 256.0 663 664 665 667 669 553 571 575 644 646 645 647.0 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TYR IGF1R IGF1R_HUMAN 4D2RA P08069 985 1286 1367.0 DYK:2288 Type1 Inactive DFGin 6.1705 16.2033 None -69.68, 163.13 -53.49, 135.63 -66.9, 144.51 304.26, 163.38 61.31, 29.83 out-out out 10.2666 Saltbr-out 6.6469 HRD-in -70.04, -49.33 73.87, -13.98 out-out-in SNCooi out-in ActLoopNT-out 17.4892 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -74.92, 112.08 APE9-dihe-in -125.82, 147.19 APE8-dihe-in -85.98, 69.81 APE8-rot-na 32.75 APE67-dihe-in -73.08, -8.74 -50.8, -35.19 APE12-dist-na 21.9009 APE11-dist-na 17.0339 APE10-dist-na 13.4169 APE9-dist-in 7.156 None None None XRAY 2.1 0.181 0.221 A 302.0 300.0 2 30 28 2 [[999, 1268]] 1.0 4d2r TYR_IGF1R_HUMAN TYR 1.8e-95 325.1 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor

Ligand: DYK

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 4D2SA
DFGin None 1 50.0% 4D2RA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
OTHER TTK TTK_HUMAN 4D2SA P33981 513 793 857.0 DYK:1794 Type1 Inactive DFGin 4.2732 14.7666 ABAminus -95.21, -44.96 -135.94, 172.0 -115.3, 6.49 305.25, 149.5 77.48, -1.71 out-out out 10.7098 Saltbr-out 6.6144 HRD-in -50.94, -45.09 68.46, -25.84 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 127.79 APE8-rot-out 187.01 APE67-dihe-in -52.43, -42.93 -100.42, -1.9 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.5 0.181 0.221 A 284.0 249.0 32 30 13 17 [[525, 791]] 1.0 4d2s Homo sapiens OTHER_TTK_HUMAN CAMK 5.8e-54 189.0 1.0 256.0 256.0 663 664 665 667 669 553 571 575 644 646 645 647.0 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TYR IGF1R IGF1R_HUMAN 4D2RA P08069 985 1286 1367.0 DYK:2288 Type1 Inactive DFGin 6.1705 16.2033 None -69.68, 163.13 -53.49, 135.63 -66.9, 144.51 304.26, 163.38 61.31, 29.83 out-out out 10.2666 Saltbr-out 6.6469 HRD-in -70.04, -49.33 73.87, -13.98 out-out-in SNCooi out-in ActLoopNT-out 17.4892 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -74.92, 112.08 APE9-dihe-in -125.82, 147.19 APE8-dihe-in -85.98, 69.81 APE8-rot-na 32.75 APE67-dihe-in -73.08, -8.74 -50.8, -35.19 APE12-dist-na 21.9009 APE11-dist-na 17.0339 APE10-dist-na 13.4169 APE9-dist-in 7.156 None None None XRAY 2.1 0.181 0.221 A 302.0 300.0 2 30 28 2 [[999, 1268]] 1.0 4d2r Homo sapiens TYR_IGF1R_HUMAN TYR 1.8e-95 325.1 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor

Ligand: DYK

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name