Ligand: AQ8

Total number of chains: 3
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 5OTHA
DFGin None 1 33.3% 9BRIA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AGC GRK5 GRK5_HUMAN 9BRIA 2.9 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1AQ8 Type1 25 - 542 0 None D311N G protein-coupled receptor kinase 5
CMGC CSNK2A1 CSK21_HUMAN 5OTHA 1.69 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AQ8 Allosteric 3 - 328 0 None R21S Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 5OTHB 1.69 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AQ8 Allosteric 4 - 327 0 None R21S Casein kinase II subunit alpha

Ligand: AQ8

Total number of chains: 3
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 5OTHA
DFGin None 1 33.3% 9BRIA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
AGC GRK5 GRK5_HUMAN 9BRIA 2.9 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1AQ8 Type1 25 - 542 0 None D311N G protein-coupled receptor kinase 5 Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 5OTHA 1.69 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AQ8 Allosteric 3 - 328 0 None R21S Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 5OTHB 1.69 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AQ8 Allosteric 4 - 327 0 None R21S Casein kinase II subunit alpha Homo sapiens

Ligand: AQ8

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism