Ligand: 5U5

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 66.7% 5EYMA
DFGin None 1 33.3% 5MAIA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CAMK MELK MELK_HUMAN 5MAIA 2.15 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 5U5 Type1 2 - 333 0 None None Maternal embryonic leucine zipper kinase
STE MAP2K1 MP2K1_HUMAN 5EYMA 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 5U5 Type1 41 - 381 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 5EYMB 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 5U5 Type1 41 - 381 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1

Ligand: 5U5

Total number of chains: 5
Active chains: 0
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 40.0% 5EYKB
DFGin BLBplus 2 40.0% 5EYMA
DFGin None 1 20.0% 5MAIA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CAMK MELK MELK_HUMAN 5MAIA 2.15 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 5U5 Type1 2 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
STE MAP2K1 MP2K1_HUMAN 5EYMA 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 5U5 Type1 41 - 381 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 5EYMB 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 5U5 Type1 41 - 381 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
CAMK AURKBA AUKBA_XENLA 5EYKB 1.93 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 5U5 Type1 81 - 356 0 TPO248 G96V Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 5EYKA 1.93 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 5U5 Type1.5_Back 88 - 355 0 TPO248 G96V Aurora kinase B-A Xenopus laevis

Ligand: 5U5

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 5EYKB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CAMK AURKBA AUKBA_XENLA 5EYKB 1.93 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 5U5 Type1 81 - 356 0 TPO248 G96V Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 5EYKA 1.93 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 5U5 Type1.5_Back 88 - 355 0 TPO248 G96V Aurora kinase B-A Xenopus laevis