Ligand: 03X

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 1 50.0% 3U6HA
DFGout BBAminus 1 50.0% 3U6JA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR KDR VGFR2_HUMAN 3U6JA 2.15 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 03X Type2 815 - 1171 0 None V916T,E990V Vascular endothelial growth factor receptor 2
TYR MET MET_HUMAN 3U6HA 2.0 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 03X Type1.5_Front 1051 - 1351 0 None None Hepatocyte growth factor receptor

Ligand: 03X

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 1 50.0% 3U6HA
DFGout BBAminus 1 50.0% 3U6JA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR KDR VGFR2_HUMAN 3U6JA 2.15 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 03X Type2 815 - 1171 0 None V916T,E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR MET MET_HUMAN 3U6HA 2.0 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 03X Type1.5_Front 1051 - 1351 0 None None Hepatocyte growth factor receptor Homo sapiens

Ligand: 03X

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism