Ligand: IXQ

Total number of chains: 2
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7ZKSA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC SRPK1 SRPK1_HUMAN 7ZKSA 2.28 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IXQ Type1 67 - 655 0 None None SRSF protein kinase 1
CMGC SRPK2 SRPK2_HUMAN 7ZKXA 2.06 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IXQ Type1 70 - 687 0 None None SRSF protein kinase 2

Ligand: IXQ

Total number of chains: 2
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7ZKSA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC SRPK1 SRPK1_HUMAN 7ZKSA 2.28 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IXQ Type1 67 - 655 0 None None SRSF protein kinase 1 Homo sapiens
CMGC SRPK2 SRPK2_HUMAN 7ZKXA 2.06 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IXQ Type1 70 - 687 0 None None SRSF protein kinase 2 Homo sapiens

Ligand: IXQ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism