AGC_RPS6KA6-1 (Ribosomal protein S6 kinase alpha-6)

Total number of chains: 8
Active chains: 2
Uniprot: KS6A6_HUMAN
Kinase Domain Residues: 73 - 330
Spatial label Dihedral label Number of Chains Percent Representative
DFGinter None 4 50.0% 6G76A
DFGin BLAminus 2 25.0% AF-Q9UK32-K1A
DFGin None 2 25.0% 6G77A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q9UK32-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 65 - 338 0 None None Ribosomal protein S6 kinase alpha-6
AF-Q9UK32-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 65 - 338 0 None None Ribosomal protein S6 kinase alpha-6
6G77A 2.499 Inactive DFGin‑None none-none out-out nonTYR APEdihe_aaiii APEdist_iooi ANP, ANP Allosteric, ATPlike 51 - 349 0 None None Ribosomal protein S6 kinase alpha-6
6G77B 2.499 Inactive DFGin‑None none-none out-out nonTYR APEdihe_aaiii APEdist_iooi ANP, ANP Allosteric, ATPlike 51 - 349 0 None None Ribosomal protein S6 kinase alpha-6
6G76B 3.0 Inactive DFGinter‑None none-none out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 51 - 349 0 SEP232 None Ribosomal protein S6 kinase alpha-6
6G78A 2.5 Inactive DFGinter‑None none-none out-out nonTYR APEdihe_aaoii APEdist_nnno ANP ATPlike 51 - 349 0 None S232E Ribosomal protein S6 kinase alpha-6
6G78B 2.5 Inactive DFGinter‑None none-none out-out nonTYR APEdihe_aaiii APEdist_nnno ANP ATPlike 51 - 349 0 None S232E Ribosomal protein S6 kinase alpha-6
6G76A 3.0 Inactive DFGinter‑None none-none out-out nonTYR APEdihe_aaiii APEdist_iooi ANP, ANP ATPlike, Allosteric 51 - 349 0 SEP232 None Ribosomal protein S6 kinase alpha-6

AGC_RPS6KA6-1 (Ribosomal protein S6 kinase alpha-6)

Total number of chains: 8
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGinter None 4 50.0% 6G76A
DFGin BLAminus 2 25.0% AF-Q9UK32-K1A
DFGin None 2 25.0% 6G77A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
KS6A6_HUMAN AF-Q9UK32-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 65 - 338 0 None None Ribosomal protein S6 kinase alpha-6 Homo sapiens
KS6A6_HUMAN AF-Q9UK32-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 65 - 338 0 None None Ribosomal protein S6 kinase alpha-6 Homo sapiens
KS6A6_HUMAN 6G77A 2.499 Inactive DFGin‑None none-none out-out nonTYR APEdihe_aaiii APEdist_iooi ANP, ANP Allosteric, ATPlike 51 - 349 0 None None Ribosomal protein S6 kinase alpha-6 Homo sapiens
KS6A6_HUMAN 6G77B 2.499 Inactive DFGin‑None none-none out-out nonTYR APEdihe_aaiii APEdist_iooi ANP, ANP Allosteric, ATPlike 51 - 349 0 None None Ribosomal protein S6 kinase alpha-6 Homo sapiens
KS6A6_HUMAN 6G76B 3.0 Inactive DFGinter‑None none-none out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 51 - 349 0 SEP232 None Ribosomal protein S6 kinase alpha-6 Homo sapiens
KS6A6_HUMAN 6G78A 2.5 Inactive DFGinter‑None none-none out-out nonTYR APEdihe_aaoii APEdist_nnno ANP ATPlike 51 - 349 0 None S232E Ribosomal protein S6 kinase alpha-6 Homo sapiens
KS6A6_HUMAN 6G78B 2.5 Inactive DFGinter‑None none-none out-out nonTYR APEdihe_aaiii APEdist_nnno ANP ATPlike 51 - 349 0 None S232E Ribosomal protein S6 kinase alpha-6 Homo sapiens
KS6A6_HUMAN 6G76A 3.0 Inactive DFGinter‑None none-none out-out nonTYR APEdihe_aaiii APEdist_iooi ANP, ANP ATPlike, Allosteric 51 - 349 0 SEP232 None Ribosomal protein S6 kinase alpha-6 Homo sapiens

AGC_RPS6KA6-1 (Ribosomal protein S6 kinase alpha-6)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism