AGC_RPS6KA6-1 (Ribosomal protein S6 kinase alpha-6)

Total number of chains: 8
Active chains: 2
Uniprot: KS6A6_HUMAN
Kinase Domain Residues: 73 - 330
Spatial label Dihedral label Number of Chains Percent Representative
DFGinter None 4 50.0% 6G76A
DFGin BLAminus 2 25.0% AF-Q9UK32-K1A
DFGin None 2 25.0% 6G77A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
RPS6KA6-1 AF-Q9UK32-K1A Q9UK32 65 338 745.0 No_ligand No_ligand Active DFGin 6.7166 14.3798 BLAminus -122.74, -167.91 42.21, 63.67 -74.28, 13.2 286.97, 79.25 -62.83, -17.84 in-in in 8.9573 Saltbr-in 2.6173 HRD-in -80.3, -49.99 66.24, 7.44 in-in-in SNCiii in-in ActLoopNT-in 2.9045 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.5, 163.94 APE9-dihe-na 113.91, 169.75 APE8-dihe-in -69.91, 129.74 APE8-rot-in 294.78 APE67-dihe-in -61.58, -27.56 -58.44, -40.04 APE12-dist-in 8.3195 APE11-dist-in 11.3217 APE10-dist-in 5.6129 APE9-dist-in 3.5642 None None None AF2 -1.0 1.0 1.0 A 274.0 274.0 0 28 28 0 [[73, 330], [426, 683]] 2.0 AF-Q9UK32-K1 AGC_RPS6KA6-1_HUMAN AGC 7.4e-98 332.7 1.0 260.0 260.0 215 216 217 219 221 105 123 127 195 197 196 198.0 255 243 238 237 236 235 234 233 232 153 Ribosomal protein S6 kinase alpha-6
RPS6KA6-1 AF-Q9UK32-K3A Q9UK32 65 338 745.0 No_ligand No_ligand Active DFGin 6.5009 14.1016 BLAminus -132.27, -175.76 52.2, 64.77 -72.92, 11.15 296.44, 84.22 -64.03, -14.25 in-in in 8.777 Saltbr-in 2.623 HRD-in -81.65, -46.67 67.29, 10.6 in-in-in SNCiii in-in ActLoopNT-in 2.8067 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.4, 164.19 APE9-dihe-na 112.49, 174.41 APE8-dihe-in -75.23, 135.24 APE8-rot-in 295.17 APE67-dihe-in -61.93, -26.66 -66.02, -39.52 APE12-dist-in 8.4234 APE11-dist-in 11.441 APE10-dist-in 5.6939 APE9-dist-in 3.3677 None None None AF2 -1.0 1.0 1.0 A 274.0 274.0 0 28 28 0 [[73, 330], [426, 683]] 2.0 AF-Q9UK32-K3 AGC_RPS6KA6-1_HUMAN AGC 7.4e-98 332.7 1.0 260.0 260.0 215 216 217 219 221 105 123 127 195 197 196 198.0 255 243 238 237 236 235 234 233 232 153 Ribosomal protein S6 kinase alpha-6
RPS6KA6-1 6G77A Q9UK32 51 349 745.0 ANP:401,ANP:402 Allosteric,ATPlike Inactive DFGin 5.9835 11.2516 None -84.57, 1.64 -160.36, 173.95 -140.73, 41.08 33.77, 88.9 86.89, 20.77 none-none none 999.0 Saltbr-none 999.0 HRD-in -75.55, -32.96 78.36, -52.1 none-out-out SNCnoo out-out ActLoopNT-out 9.9576 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na 55.72, -148.34 APE9-dihe-na -103.74, -158.66 APE8-dihe-in -91.11, 113.9 APE8-rot-in 297.76 APE67-dihe-in -53.19, -20.32 -55.54, -41.19 APE12-dist-in 13.7321 APE11-dist-out 15.8714 APE10-dist-out 13.5037 APE9-dist-in 5.5319 None None None XRAY 2.499 0.188 0.233 A 307.0 291.0 8 28 28 0 [[73, 330], [426, 683]] 2.0 6g77 AGC_RPS6KA6-1_HUMAN AGC 1.1e-97 332.1 1.0 260.0 260.0 215 216 217 219 221 105 123 127 195 197 196 198.0 255 243 238 237 236 235 234 233 232 153 Ribosomal protein S6 kinase alpha-6
RPS6KA6-1 6G77B Q9UK32 51 349 745.0 ANP:401,ANP:402 Allosteric,ATPlike Inactive DFGin 5.612 11.3114 None -84.74, -2.79 -145.41, 176.89 -143.69, 39.64 45.89, 82.52 94.84, 15.56 none-none none 999.0 Saltbr-none 999.0 HRD-in -77.95, -30.79 74.87, -47.1 none-out-out SNCnoo out-out ActLoopNT-out 10.0706 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na 55.75, -144.28 APE9-dihe-na -119.2, -153.74 APE8-dihe-in -83.74, 120.03 APE8-rot-in 297.54 APE67-dihe-in -52.98, -34.42 -57.71, -42.71 APE12-dist-in 13.9149 APE11-dist-out 16.0857 APE10-dist-out 13.633 APE9-dist-in 5.5223 None None None XRAY 2.499 0.188 0.233 B 307.0 291.0 8 28 28 0 [[73, 330], [426, 683]] 2.0 6g77 AGC_RPS6KA6-1_HUMAN AGC 1.1e-97 332.1 1.0 260.0 260.0 215 216 217 219 221 105 123 127 195 197 196 198.0 255 243 238 237 236 235 234 233 232 153 Ribosomal protein S6 kinase alpha-6
RPS6KA6-1 6G76B Q9UK32 51 349 745.0 ANP:401 ATPlike Inactive DFGinter 5.7966 10.9823 None -66.14, -24.76 -146.8, 171.15 -130.39, 64.5 31.65, 91.02 69.21, 34.12 none-none none 999.0 Saltbr-none 999.0 HRD-in -64.7, -28.83 65.1, -58.97 none-out-none SNCnon out-none ActLoopNT-out 9.714 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -65.75, -19.3 999.0, -17.78 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None SEP232 SEP232 XRAY 3.0 0.226 0.268 B 307.0 269.0 30 28 17 11 [[73, 330], [426, 683]] 2.0 6g76 AGC_RPS6KA6-1_HUMAN AGC 1.1e-97 332.1 1.0 260.0 260.0 215 216 217 219 221 105 123 127 195 197 196 198.0 255 243 238 237 236 235 234 233 232 153 Ribosomal protein S6 kinase alpha-6
RPS6KA6-1 6G78A Q9UK32 51 349 745.0 ANP:401 ATPlike Inactive DFGinter 6.2685 10.6336 None -86.41, -10.47 -141.48, -170.45 -156.88, 52.15 42.27, 88.32 84.48, 16.59 none-none none 999.0 Saltbr-none 999.0 HRD-in -69.26, -28.88 63.94, -61.25 none-out-out SNCnoo out-out ActLoopNT-out 9.5896 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 82.23 APE8-dihe-out 57.69, 79.35 APE8-rot-in 324.77 APE67-dihe-in -47.93, -24.91 -65.59, -33.86 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 7.9125 S232E None None XRAY 2.5 0.227 0.24 A 307.0 283.0 16 28 20 8 [[73, 330], [426, 683]] 2.0 6g78 AGC_RPS6KA6-1_HUMAN AGC 1.4e-97 331.8 1.0 260.0 260.0 215 216 217 219 221 105 123 127 195 197 196 198.0 255 243 238 237 236 235 234 233 232 153 Ribosomal protein S6 kinase alpha-6
RPS6KA6-1 6G78B Q9UK32 51 349 745.0 ANP:401 ATPlike Inactive DFGinter 5.64 10.7376 None -79.92, -10.17 -139.49, -179.53 -146.16, 53.91 40.8, 75.5 84.23, 17.04 none-none none 999.0 Saltbr-none 999.0 HRD-in -71.51, -26.87 55.09, -79.87 none-out-out SNCnoo out-out ActLoopNT-out 9.8393 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -162.93 APE8-dihe-in -60.6, 118.59 APE8-rot-in 321.37 APE67-dihe-in -66.02, -21.47 -64.56, -33.48 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 6.8452 S232E None None XRAY 2.5 0.227 0.24 B 307.0 281.0 18 28 18 10 [[73, 330], [426, 683]] 2.0 6g78 AGC_RPS6KA6-1_HUMAN AGC 1.4e-97 331.8 1.0 260.0 260.0 215 216 217 219 221 105 123 127 195 197 196 198.0 255 243 238 237 236 235 234 233 232 153 Ribosomal protein S6 kinase alpha-6
RPS6KA6-1 6G76A Q9UK32 51 349 745.0 ANP:401,ANP:402 ATPlike,Allosteric Inactive DFGinter 6.2614 10.8766 None -85.39, -13.66 -143.61, 178.12 -143.21, 50.96 33.86, 88.85 75.03, 27.38 none-none none 999.0 Saltbr-none 999.0 HRD-in -70.26, -5.92 45.43, -59.01 none-out-out SNCnoo out-out ActLoopNT-out 9.8423 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na 52.64, -135.92 APE9-dihe-na -103.88, -148.96 APE8-dihe-in -100.12, 127.8 APE8-rot-in 306.8 APE67-dihe-in -56.57, -28.02 -70.04, -37.97 APE12-dist-in 13.9093 APE11-dist-out 16.2474 APE10-dist-out 12.7459 APE9-dist-in 5.5959 None SEP232 SEP232 XRAY 3.0 0.226 0.268 A 307.0 291.0 8 28 28 0 [[73, 330], [426, 683]] 2.0 6g76 AGC_RPS6KA6-1_HUMAN AGC 1.1e-97 332.1 1.0 260.0 260.0 215 216 217 219 221 105 123 127 195 197 196 198.0 255 243 238 237 236 235 234 233 232 153 Ribosomal protein S6 kinase alpha-6

AGC_RPS6KA6-1 (Ribosomal protein S6 kinase alpha-6)

Total number of chains: 8
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGinter None 4 50.0% 6G76A
DFGin BLAminus 2 25.0% AF-Q9UK32-K1A
DFGin None 2 25.0% 6G77A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
RPS6KA6-1 KS6A6_HUMAN AF-Q9UK32-K1A Q9UK32 65 338 745.0 No_ligand No_ligand Active DFGin 6.7166 14.3798 BLAminus -122.74, -167.91 42.21, 63.67 -74.28, 13.2 286.97, 79.25 -62.83, -17.84 in-in in 8.9573 Saltbr-in 2.6173 HRD-in -80.3, -49.99 66.24, 7.44 in-in-in SNCiii in-in ActLoopNT-in 2.9045 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.5, 163.94 APE9-dihe-na 113.91, 169.75 APE8-dihe-in -69.91, 129.74 APE8-rot-in 294.78 APE67-dihe-in -61.58, -27.56 -58.44, -40.04 APE12-dist-in 8.3195 APE11-dist-in 11.3217 APE10-dist-in 5.6129 APE9-dist-in 3.5642 None None None AF2 -1.0 1.0 1.0 A 274.0 274.0 0 28 28 0 [[73, 330], [426, 683]] 2.0 AF-Q9UK32-K1 Homo sapiens AGC_RPS6KA6-1_HUMAN AGC 7.4e-98 332.7 1.0 260.0 260.0 215 216 217 219 221 105 123 127 195 197 196 198.0 255 243 238 237 236 235 234 233 232 153 Ribosomal protein S6 kinase alpha-6
RPS6KA6-1 KS6A6_HUMAN AF-Q9UK32-K3A Q9UK32 65 338 745.0 No_ligand No_ligand Active DFGin 6.5009 14.1016 BLAminus -132.27, -175.76 52.2, 64.77 -72.92, 11.15 296.44, 84.22 -64.03, -14.25 in-in in 8.777 Saltbr-in 2.623 HRD-in -81.65, -46.67 67.29, 10.6 in-in-in SNCiii in-in ActLoopNT-in 2.8067 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.4, 164.19 APE9-dihe-na 112.49, 174.41 APE8-dihe-in -75.23, 135.24 APE8-rot-in 295.17 APE67-dihe-in -61.93, -26.66 -66.02, -39.52 APE12-dist-in 8.4234 APE11-dist-in 11.441 APE10-dist-in 5.6939 APE9-dist-in 3.3677 None None None AF2 -1.0 1.0 1.0 A 274.0 274.0 0 28 28 0 [[73, 330], [426, 683]] 2.0 AF-Q9UK32-K3 Homo sapiens AGC_RPS6KA6-1_HUMAN AGC 7.4e-98 332.7 1.0 260.0 260.0 215 216 217 219 221 105 123 127 195 197 196 198.0 255 243 238 237 236 235 234 233 232 153 Ribosomal protein S6 kinase alpha-6
RPS6KA6-1 KS6A6_HUMAN 6G77A Q9UK32 51 349 745.0 ANP:401,ANP:402 Allosteric,ATPlike Inactive DFGin 5.9835 11.2516 None -84.57, 1.64 -160.36, 173.95 -140.73, 41.08 33.77, 88.9 86.89, 20.77 none-none none 999.0 Saltbr-none 999.0 HRD-in -75.55, -32.96 78.36, -52.1 none-out-out SNCnoo out-out ActLoopNT-out 9.9576 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na 55.72, -148.34 APE9-dihe-na -103.74, -158.66 APE8-dihe-in -91.11, 113.9 APE8-rot-in 297.76 APE67-dihe-in -53.19, -20.32 -55.54, -41.19 APE12-dist-in 13.7321 APE11-dist-out 15.8714 APE10-dist-out 13.5037 APE9-dist-in 5.5319 None None None XRAY 2.499 0.188 0.233 A 307.0 291.0 8 28 28 0 [[73, 330], [426, 683]] 2.0 6g77 Homo sapiens AGC_RPS6KA6-1_HUMAN AGC 1.1e-97 332.1 1.0 260.0 260.0 215 216 217 219 221 105 123 127 195 197 196 198.0 255 243 238 237 236 235 234 233 232 153 Ribosomal protein S6 kinase alpha-6
RPS6KA6-1 KS6A6_HUMAN 6G77B Q9UK32 51 349 745.0 ANP:401,ANP:402 Allosteric,ATPlike Inactive DFGin 5.612 11.3114 None -84.74, -2.79 -145.41, 176.89 -143.69, 39.64 45.89, 82.52 94.84, 15.56 none-none none 999.0 Saltbr-none 999.0 HRD-in -77.95, -30.79 74.87, -47.1 none-out-out SNCnoo out-out ActLoopNT-out 10.0706 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na 55.75, -144.28 APE9-dihe-na -119.2, -153.74 APE8-dihe-in -83.74, 120.03 APE8-rot-in 297.54 APE67-dihe-in -52.98, -34.42 -57.71, -42.71 APE12-dist-in 13.9149 APE11-dist-out 16.0857 APE10-dist-out 13.633 APE9-dist-in 5.5223 None None None XRAY 2.499 0.188 0.233 B 307.0 291.0 8 28 28 0 [[73, 330], [426, 683]] 2.0 6g77 Homo sapiens AGC_RPS6KA6-1_HUMAN AGC 1.1e-97 332.1 1.0 260.0 260.0 215 216 217 219 221 105 123 127 195 197 196 198.0 255 243 238 237 236 235 234 233 232 153 Ribosomal protein S6 kinase alpha-6
RPS6KA6-1 KS6A6_HUMAN 6G76B Q9UK32 51 349 745.0 ANP:401 ATPlike Inactive DFGinter 5.7966 10.9823 None -66.14, -24.76 -146.8, 171.15 -130.39, 64.5 31.65, 91.02 69.21, 34.12 none-none none 999.0 Saltbr-none 999.0 HRD-in -64.7, -28.83 65.1, -58.97 none-out-none SNCnon out-none ActLoopNT-out 9.714 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -65.75, -19.3 999.0, -17.78 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None SEP232 SEP232 XRAY 3.0 0.226 0.268 B 307.0 269.0 30 28 17 11 [[73, 330], [426, 683]] 2.0 6g76 Homo sapiens AGC_RPS6KA6-1_HUMAN AGC 1.1e-97 332.1 1.0 260.0 260.0 215 216 217 219 221 105 123 127 195 197 196 198.0 255 243 238 237 236 235 234 233 232 153 Ribosomal protein S6 kinase alpha-6
RPS6KA6-1 KS6A6_HUMAN 6G78A Q9UK32 51 349 745.0 ANP:401 ATPlike Inactive DFGinter 6.2685 10.6336 None -86.41, -10.47 -141.48, -170.45 -156.88, 52.15 42.27, 88.32 84.48, 16.59 none-none none 999.0 Saltbr-none 999.0 HRD-in -69.26, -28.88 63.94, -61.25 none-out-out SNCnoo out-out ActLoopNT-out 9.5896 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 82.23 APE8-dihe-out 57.69, 79.35 APE8-rot-in 324.77 APE67-dihe-in -47.93, -24.91 -65.59, -33.86 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 7.9125 S232E None None XRAY 2.5 0.227 0.24 A 307.0 283.0 16 28 20 8 [[73, 330], [426, 683]] 2.0 6g78 Homo sapiens AGC_RPS6KA6-1_HUMAN AGC 1.4e-97 331.8 1.0 260.0 260.0 215 216 217 219 221 105 123 127 195 197 196 198.0 255 243 238 237 236 235 234 233 232 153 Ribosomal protein S6 kinase alpha-6
RPS6KA6-1 KS6A6_HUMAN 6G78B Q9UK32 51 349 745.0 ANP:401 ATPlike Inactive DFGinter 5.64 10.7376 None -79.92, -10.17 -139.49, -179.53 -146.16, 53.91 40.8, 75.5 84.23, 17.04 none-none none 999.0 Saltbr-none 999.0 HRD-in -71.51, -26.87 55.09, -79.87 none-out-out SNCnoo out-out ActLoopNT-out 9.8393 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -162.93 APE8-dihe-in -60.6, 118.59 APE8-rot-in 321.37 APE67-dihe-in -66.02, -21.47 -64.56, -33.48 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 6.8452 S232E None None XRAY 2.5 0.227 0.24 B 307.0 281.0 18 28 18 10 [[73, 330], [426, 683]] 2.0 6g78 Homo sapiens AGC_RPS6KA6-1_HUMAN AGC 1.4e-97 331.8 1.0 260.0 260.0 215 216 217 219 221 105 123 127 195 197 196 198.0 255 243 238 237 236 235 234 233 232 153 Ribosomal protein S6 kinase alpha-6
RPS6KA6-1 KS6A6_HUMAN 6G76A Q9UK32 51 349 745.0 ANP:401,ANP:402 ATPlike,Allosteric Inactive DFGinter 6.2614 10.8766 None -85.39, -13.66 -143.61, 178.12 -143.21, 50.96 33.86, 88.85 75.03, 27.38 none-none none 999.0 Saltbr-none 999.0 HRD-in -70.26, -5.92 45.43, -59.01 none-out-out SNCnoo out-out ActLoopNT-out 9.8423 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na 52.64, -135.92 APE9-dihe-na -103.88, -148.96 APE8-dihe-in -100.12, 127.8 APE8-rot-in 306.8 APE67-dihe-in -56.57, -28.02 -70.04, -37.97 APE12-dist-in 13.9093 APE11-dist-out 16.2474 APE10-dist-out 12.7459 APE9-dist-in 5.5959 None SEP232 SEP232 XRAY 3.0 0.226 0.268 A 307.0 291.0 8 28 28 0 [[73, 330], [426, 683]] 2.0 6g76 Homo sapiens AGC_RPS6KA6-1_HUMAN AGC 1.1e-97 332.1 1.0 260.0 260.0 215 216 217 219 221 105 123 127 195 197 196 198.0 255 243 238 237 236 235 234 233 232 153 Ribosomal protein S6 kinase alpha-6

AGC_RPS6KA6-1 (Ribosomal protein S6 kinase alpha-6)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name