CMGC_MAPK11 (Mitogen-activated protein kinase 11)

Total number of chains: 8
Active chains: 2
Uniprot: MK11_HUMAN
Kinase Domain Residues: 24 - 308
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 37.5% 3GC8A
DFGin BLAminus 2 25.0% AF-Q15759-K1A
DFGin None 1 12.5% 3GC9A
DFGout BBAminus 1 12.5% 3GP0A
DFGout None 1 12.5% 8YGWA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q15759-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 16 - 316 0 None None Mitogen-activated protein kinase 11
AF-Q15759-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 16 - 316 0 None None Mitogen-activated protein kinase 11
3GC9B 2.05 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnoo B45 Type1 2 - 349 0 None C119S,C162S Mitogen-activated protein kinase 11
3GC8A 2.4 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_iooo B45 Type1 3 - 349 0 None C162S Mitogen-activated protein kinase 11
3GC8B 2.4 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_oooo B45 Type1 4 - 349 0 None C162S Mitogen-activated protein kinase 11
3GC9A 2.05 Inactive DFGin‑None in-out none-out nonTYR APEdihe_aaioi APEdist_nnno B45 Type1 3 - 348 0 None C119S,C162S Mitogen-activated protein kinase 11
3GP0A 1.9 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno NIL Type2 5 - 348 0 None None Mitogen-activated protein kinase 11
8YGWA 3.301 Inactive DFGout‑None in-out none-out nonTYR APEdihe_aaoii APEdist_nnno B96 Type2 5 - 348 0 None None Mitogen-activated protein kinase 11

CMGC_MAPK11 (Mitogen-activated protein kinase 11)

Total number of chains: 8
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 37.5% 3GC8A
DFGin BLAminus 2 25.0% AF-Q15759-K1A
DFGin None 1 12.5% 3GC9A
DFGout BBAminus 1 12.5% 3GP0A
DFGout None 1 12.5% 8YGWA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
MK11_HUMAN AF-Q15759-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 16 - 316 0 None None Mitogen-activated protein kinase 11 Homo sapiens
MK11_HUMAN AF-Q15759-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 16 - 316 0 None None Mitogen-activated protein kinase 11 Homo sapiens
MK11_HUMAN 3GC9B 2.05 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnoo B45 Type1 2 - 349 0 None C119S,C162S Mitogen-activated protein kinase 11 Homo sapiens
MK11_HUMAN 3GC8A 2.4 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_iooo B45 Type1 3 - 349 0 None C162S Mitogen-activated protein kinase 11 Homo sapiens
MK11_HUMAN 3GC8B 2.4 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_oooo B45 Type1 4 - 349 0 None C162S Mitogen-activated protein kinase 11 Homo sapiens
MK11_HUMAN 3GC9A 2.05 Inactive DFGin‑None in-out none-out nonTYR APEdihe_aaioi APEdist_nnno B45 Type1 3 - 348 0 None C119S,C162S Mitogen-activated protein kinase 11 Homo sapiens
MK11_HUMAN 3GP0A 1.9 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno NIL Type2 5 - 348 0 None None Mitogen-activated protein kinase 11 Homo sapiens
MK11_HUMAN 8YGWA 3.301 Inactive DFGout‑None in-out none-out nonTYR APEdihe_aaoii APEdist_nnno B96 Type2 5 - 348 0 None None Mitogen-activated protein kinase 11 Homo sapiens

CMGC_MAPK11 (Mitogen-activated protein kinase 11)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Hover over column headers for tooltip help

UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism