TYR_FLT3 (Receptor-type tyrosine-protein kinase FLT3)

Total number of chains: 10
Active chains: 2
Uniprot: FLT3_HUMAN
Kinase Domain Residues: 610 - 945
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 5 50.0% 6IL3A
DFGout BBAminus 3 30.0% 4XUFB
DFGin BLAminus 2 20.0% AF-P36888-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P36888-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 602 - 953 0 None None Receptor-type tyrosine-protein kinase FLT3
AF-P36888-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 602 - 953 0 None None Receptor-type tyrosine-protein kinase FLT3
4XUFA 3.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P30 Type2 600 - 947 0 None None Receptor-type tyrosine-protein kinase FLT3
4XUFB 3.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P30 Type2 600 - 946 0 None None Receptor-type tyrosine-protein kinase FLT3
4RT7A 3.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P30 Type2 599 - 950 0 None None Receptor-type tyrosine-protein kinase FLT3
1RJBA 2.1 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 572 - 947 0 None None Receptor-type tyrosine-protein kinase FLT3
6JQRA 2.2 Inactive DFGout‑None in-in none-in TYR APEdihe_iiiai APEdist_aaai C6F Type1 571 - 951 0 None None Receptor-type tyrosine-protein kinase FLT3
8XB1A 2.85 Inactive DFGout‑None in-in none-in TYR APEdihe_iiiai APEdist_aaai ZX3 Type1 573 - 950 0 None None Receptor-type tyrosine-protein kinase FLT3
5X02A 2.401 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai F6M Type1 573 - 947 0 None None Receptor-type tyrosine-protein kinase FLT3
6IL3A 2.5 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai A9R Type1 569 - 947 0 None None Receptor-type tyrosine-protein kinase FLT3

TYR_FLT3 (Receptor-type tyrosine-protein kinase FLT3)

Total number of chains: 10
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 5 50.0% 6IL3A
DFGout BBAminus 3 30.0% 4XUFB
DFGin BLAminus 2 20.0% AF-P36888-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
FLT3_HUMAN AF-P36888-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 602 - 953 0 None None Receptor-type tyrosine-protein kinase FLT3 Homo sapiens
FLT3_HUMAN AF-P36888-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 602 - 953 0 None None Receptor-type tyrosine-protein kinase FLT3 Homo sapiens
FLT3_HUMAN 4XUFA 3.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P30 Type2 600 - 947 0 None None Receptor-type tyrosine-protein kinase FLT3 Homo sapiens
FLT3_HUMAN 4XUFB 3.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P30 Type2 600 - 946 0 None None Receptor-type tyrosine-protein kinase FLT3 Homo sapiens
FLT3_HUMAN 4RT7A 3.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P30 Type2 599 - 950 0 None None Receptor-type tyrosine-protein kinase FLT3 Homo sapiens
FLT3_HUMAN 1RJBA 2.1 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 572 - 947 0 None None Receptor-type tyrosine-protein kinase FLT3 Homo sapiens
FLT3_HUMAN 6JQRA 2.2 Inactive DFGout‑None in-in none-in TYR APEdihe_iiiai APEdist_aaai C6F Type1 571 - 951 0 None None Receptor-type tyrosine-protein kinase FLT3 Homo sapiens
FLT3_HUMAN 8XB1A 2.85 Inactive DFGout‑None in-in none-in TYR APEdihe_iiiai APEdist_aaai ZX3 Type1 573 - 950 0 None None Receptor-type tyrosine-protein kinase FLT3 Homo sapiens
FLT3_HUMAN 5X02A 2.401 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai F6M Type1 573 - 947 0 None None Receptor-type tyrosine-protein kinase FLT3 Homo sapiens
FLT3_HUMAN 6IL3A 2.5 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai A9R Type1 569 - 947 0 None None Receptor-type tyrosine-protein kinase FLT3 Homo sapiens

TYR_FLT3 (Receptor-type tyrosine-protein kinase FLT3)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism