CMGC_CSNK2A2 (Casein kinase II subunit alpha')

Total number of chains: 70
Active chains: 24
Family: CMGC
Uniprot: CSK22_HUMAN
Kinase Domain Residues: 40 - 325
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 69 98.6% AF-P19784-K1A
DFGin None 1 1.4% 3E3BX
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

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PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
8QCGB 7 333 350.0 ANP:401 ATPlike Active DFGin 7.314 16.209 BLAminus -113.91, -178.96 61.11, 75.42 -92.86, 17.98 298.38, 79.8 -69.62, -20.0 in-in in 9.436 Saltbr-in 2.83 HRD-in -72.51, -49.6 69.57, 9.93 in-in-in SNCiii in-in ActLoopNT-in 2.828 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.91, 170.94 APE9-dihe-na 61.2, 166.37 APE8-dihe-in -93.43, 149.98 APE8-rot-in 300.62 APE67-dihe-in -69.2, -15.18 -40.28, -54.89 APE12-dist-in 12.657 APE11-dist-in 10.295 APE10-dist-in 6.172 APE9-dist-in 3.11 C336S None None XRAY 1.04 0.151 0.17 B 364 327 0 0 0 0 [[40, 325]] 1.0 8qcg CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9R5CA 7 333 350.0 A1JCZ:401,4B0:402 Allosteric,Type1 Active DFGin 7.352 15.879 BLAminus -111.92, 178.27 56.34, 80.71 -93.81, 15.08 294.28, 82.0 -67.7, -19.18 in-in in 9.075 Saltbr-in 2.756 HRD-in -75.1, -50.02 71.31, 12.54 in-in-in SNCiii in-in ActLoopNT-in 2.854 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.89, 171.36 APE9-dihe-na 64.09, 173.29 APE8-dihe-in -103.87, 145.44 APE8-rot-in 299.19 APE67-dihe-in -66.53, -19.64 -38.47, -55.07 APE12-dist-in 12.613 APE11-dist-in 10.212 APE10-dist-in 6.156 APE9-dist-in 3.065 C336S None None XRAY 1.04 0.145 0.164 A 364 327 0 0 0 0 [[40, 325]] 1.0 9r5c CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
AF-P19784-K1A 32 333 350.0 No_ligand No_ligand Active DFGin 7.369 16.199 BLAminus -121.39, 176.39 61.24, 58.28 -72.82, 13.59 297.09, 82.11 -66.04, -26.53 in-in in 9.369 Saltbr-in 2.693 HRD-in -74.33, -45.67 62.63, 13.83 in-in-in SNCiii in-in ActLoopNT-in 2.899 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -115.93, 172.73 APE9-dihe-na 59.18, 158.52 APE8-dihe-in -78.25, 144.4 APE8-rot-in 303.66 APE67-dihe-in -67.32, -14.94 -43.74, -50.78 APE12-dist-in 12.633 APE11-dist-in 10.459 APE10-dist-in 6.047 APE9-dist-in 3.297 None None None AF2 -1.0 1.0 1.0 A 302 302 0 0 0 0 [[40, 325]] 1.0 AF-P19784-K1 CMGC_CSNK2A2_HUMAN CMGC 5.3e-70 241.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
AF-P19784-K3A 32 333 350.0 No_ligand No_ligand Active DFGin 7.224 16.168 BLAminus -123.84, 175.15 62.02, 53.43 -64.54, 11.55 298.79, 84.22 -66.31, -24.89 in-in in 9.288 Saltbr-in 2.689 HRD-in -77.16, -42.8 61.58, 14.61 in-in-in SNCiii in-in ActLoopNT-in 2.925 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -115.92, 172.28 APE9-dihe-na 57.3, 148.18 APE8-dihe-in -74.15, 142.51 APE8-rot-in 301.25 APE67-dihe-in -68.42, -14.07 -40.82, -53.0 APE12-dist-in 12.443 APE11-dist-in 10.151 APE10-dist-in 6.001 APE9-dist-in 3.256 None None None AF2 -1.0 1.0 1.0 A 302 302 0 0 0 0 [[40, 325]] 1.0 AF-P19784-K3 CMGC_CSNK2A2_HUMAN CMGC 5.3e-70 241.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
8QF1B 7 333 350.0 No_ligand No_ligand Active DFGin 7.389 16.15 BLAminus -120.85, -177.74 54.7, 88.15 -104.97, 18.42 294.01, 82.89 -68.69, -20.02 in-in in 9.509 Saltbr-in 3.045 HRD-in -75.42, -49.34 71.04, 8.42 in-in-in SNCiii in-in ActLoopNT-in 2.833 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.85, 175.43 APE9-dihe-na 63.75, 177.89 APE8-dihe-in -108.49, 146.29 APE8-rot-in 295.14 APE67-dihe-in -65.54, -16.58 -41.79, -51.59 APE12-dist-in 12.784 APE11-dist-in 10.377 APE10-dist-in 6.189 APE9-dist-in 2.983 C336S None None XRAY 1.32 0.214 0.232 B 364 327 0 0 0 0 [[40, 325]] 1.0 8qf1 CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
6QY8A 8 330 350.0 041:500 Type1 Active DFGin 7.384 16.141 BLAminus -120.12, 176.92 53.95, 78.53 -91.82, 22.02 295.47, 79.33 -73.46, -14.93 in-in in 9.506 Saltbr-in 2.748 HRD-in -74.68, -55.45 73.72, 15.02 in-in-in SNCiii in-in ActLoopNT-in 2.872 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.61, 171.26 APE9-dihe-na 56.4, 177.65 APE8-dihe-in -106.07, 146.22 APE8-rot-in 310.11 APE67-dihe-in -67.75, -14.94 -42.59, -51.92 APE12-dist-in 12.331 APE11-dist-in 9.826 APE10-dist-in 5.991 APE9-dist-in 3.178 None None None XRAY 1.7 0.265 0.291 A 336 321 2 0 0 0 [[40, 325]] 1.0 6qy8 CMGC_CSNK2A2_HUMAN CMGC 7.8e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
6QY8B 8 332 350.0 041:500 Type1 Active DFGin 7.393 16.185 BLAminus -118.01, 175.97 55.87, 77.94 -91.32, 21.09 292.85, 80.76 -71.72, -13.94 in-in in 9.604 Saltbr-in 2.771 HRD-in -73.14, -53.85 71.23, 15.63 in-in-in SNCiii in-in ActLoopNT-in 2.879 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.98, 172.57 APE9-dihe-na 61.84, 175.34 APE8-dihe-in -104.11, 145.88 APE8-rot-in 310.29 APE67-dihe-in -68.68, -14.13 -40.25, -52.48 APE12-dist-in 12.492 APE11-dist-in 10.014 APE10-dist-in 6.056 APE9-dist-in 3.154 None None None XRAY 1.7 0.265 0.291 B 336 323 2 0 0 0 [[40, 325]] 1.0 6qy8 CMGC_CSNK2A2_HUMAN CMGC 7.8e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
6QY8C 8 332 350.0 041:500 Type1 Active DFGin 7.396 16.108 BLAminus -117.04, 176.75 55.38, 77.75 -90.54, 20.88 296.94, 80.84 -70.87, -18.26 in-in in 9.556 Saltbr-in 2.774 HRD-in -73.1, -54.09 70.1, 18.8 in-in-in SNCiii in-in ActLoopNT-in 2.884 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.13, 171.16 APE9-dihe-na 62.91, 176.48 APE8-dihe-in -108.0, 146.42 APE8-rot-in 311.4 APE67-dihe-in -68.5, -13.94 -43.41, -50.54 APE12-dist-in 12.419 APE11-dist-in 9.882 APE10-dist-in 5.98 APE9-dist-in 3.143 None None None XRAY 1.7 0.265 0.291 C 336 325 0 0 0 0 [[40, 325]] 1.0 6qy8 CMGC_CSNK2A2_HUMAN CMGC 7.8e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
6QY8D 8 332 350.0 041:500 Type1 Active DFGin 7.385 16.098 BLAminus -117.58, 176.73 55.17, 76.49 -91.26, 21.62 297.41, 80.15 -73.81, -12.58 in-in in 9.478 Saltbr-in 2.77 HRD-in -75.19, -54.21 74.19, 15.39 in-in-in SNCiii in-in ActLoopNT-in 2.857 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.38, 170.81 APE9-dihe-na 62.1, 174.51 APE8-dihe-in -104.94, 144.68 APE8-rot-in 310.96 APE67-dihe-in -67.06, -14.14 -40.83, -52.81 APE12-dist-in 12.571 APE11-dist-in 10.099 APE10-dist-in 6.144 APE9-dist-in 3.163 None None None XRAY 1.7 0.265 0.291 D 336 323 2 0 0 0 [[40, 325]] 1.0 6qy8 CMGC_CSNK2A2_HUMAN CMGC 7.8e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
6QY9A 7 335 350.0 JL2:401 Type1 Active DFGin 7.356 16.106 BLAminus -116.84, -178.12 52.4, 77.34 -88.44, 16.74 294.55, 80.65 -68.91, -20.63 in-in in 9.253 Saltbr-in 2.783 HRD-in -74.61, -49.29 71.4, 14.8 in-in-in SNCiii in-in ActLoopNT-in 2.86 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.06, 173.6 APE9-dihe-na 62.78, 178.89 APE8-dihe-in -108.7, 142.76 APE8-rot-in 301.62 APE67-dihe-in -69.55, -13.66 -39.9, -52.14 APE12-dist-in 12.497 APE11-dist-in 10.172 APE10-dist-in 6.187 APE9-dist-in 3.11 None None None XRAY 1.5 0.127 0.165 A 336 329 0 0 0 0 [[40, 325]] 1.0 6qy9 CMGC_CSNK2A2_HUMAN CMGC 7.8e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
6L20G 8 332 350.0 E3U:401 Type1 Active DFGin 7.284 16.005 BLAminus -127.52, -173.82 53.59, 81.78 -99.19, 29.51 292.18, 85.28 -60.52, -51.96 in-in in 9.472 Saltbr-in 3.173 HRD-in -61.14, -61.27 82.07, -26.56 in-in-in SNCiii in-in ActLoopNT-in 2.594 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.99, 171.25 APE9-dihe-na 64.2, 155.75 APE8-dihe-in -86.4, 156.84 APE8-rot-in 302.93 APE67-dihe-in -58.16, -47.73 -52.96, -55.01 APE12-dist-in 12.506 APE11-dist-in 9.924 APE10-dist-in 5.875 APE9-dist-in 3.149 None None None XRAY 3.087 0.249 0.326 G 338 319 6 0 0 0 [[40, 325]] 1.0 6l20 CMGC_CSNK2A2_HUMAN CMGC 8e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
6L20J 8 332 350.0 E3U:401 Type1 Active DFGin 7.46 16.389 BLAminus -136.61, -171.16 54.01, 68.09 -89.26, 14.98 297.06, 81.4 -59.25, -24.06 in-in in 9.903 Saltbr-in 3.253 HRD-in -60.53, -53.7 72.4, -1.96 in-in-in SNCiii in-in ActLoopNT-in 3.327 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -145.22, 173.34 APE9-dihe-na 50.03, -179.69 APE8-dihe-in -96.9, 164.64 APE8-rot-in 296.92 APE67-dihe-in -43.38, -47.79 -57.7, -61.79 APE12-dist-in 12.906 APE11-dist-in 10.476 APE10-dist-in 6.421 APE9-dist-in 2.999 None None None XRAY 3.087 0.249 0.326 J 338 314 11 0 0 0 [[40, 325]] 1.0 6l20 CMGC_CSNK2A2_HUMAN CMGC 8e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
5Y9MA 7 329 350.0 NIO:401 Type1 Active DFGin 7.413 16.17 BLAminus -114.7, 179.98 51.13, 80.68 -91.85, 19.14 294.67, 80.42 -65.77, -17.09 in-in in 9.364 Saltbr-in 2.718 HRD-in -70.56, -47.51 66.93, 6.34 in-in-in SNCiii in-in ActLoopNT-in 2.81 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.58, 175.14 APE9-dihe-na 60.0, -172.23 APE8-dihe-in -119.82, 146.83 APE8-rot-in 298.24 APE67-dihe-in -67.32, -19.61 -42.77, -51.22 APE12-dist-in 12.724 APE11-dist-in 10.493 APE10-dist-in 6.152 APE9-dist-in 3.013 None None None XRAY 2.006 0.173 0.205 A 339 320 3 0 0 0 [[40, 325]] 1.0 5y9m CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
5Y9MX 7 329 350.0 NIO:401 Type1 Active DFGin 7.419 16.296 BLAminus -114.61, -179.34 52.3, 79.76 -91.76, 19.36 295.38, 79.95 -64.7, -18.3 in-in in 9.336 Saltbr-in 2.717 HRD-in -70.29, -48.55 67.93, 5.94 in-in-in SNCiii in-in ActLoopNT-in 2.806 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.82, 175.26 APE9-dihe-na 61.28, -171.63 APE8-dihe-in -117.63, 147.87 APE8-rot-in 296.65 APE67-dihe-in -67.57, -18.73 -43.97, -52.04 APE12-dist-in 12.753 APE11-dist-in 10.798 APE10-dist-in 6.257 APE9-dist-in 3.052 None None None XRAY 2.006 0.173 0.205 X 339 319 4 0 0 0 [[40, 325]] 1.0 5y9m CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
5YF9B 6 329 350.0 NIO:401 Type1 Active DFGin 7.459 16.07 BLAminus -110.95, -179.27 53.65, 80.05 -91.28, 26.14 296.96, 82.34 -75.04, -13.81 in-in in 9.343 Saltbr-in 2.569 HRD-in -67.49, -46.45 66.2, 15.42 in-in-in SNCiii in-in ActLoopNT-in 2.969 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.9, 174.16 APE9-dihe-na 64.72, 177.19 APE8-dihe-in -102.79, 146.68 APE8-rot-in 285.72 APE67-dihe-in -62.8, -17.43 -42.57, -55.43 APE12-dist-in 12.715 APE11-dist-in 10.521 APE10-dist-in 6.167 APE9-dist-in 3.05 None None None XRAY 1.89 0.214 0.263 B 339 319 5 0 0 0 [[40, 325]] 1.0 5yf9 CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
5YF9X 6 329 350.0 NIO:401 Type1 Active DFGin 7.455 16.124 BLAminus -110.45, 178.76 52.99, 85.82 -99.51, 23.76 294.09, 79.0 -68.33, -18.31 in-in in 9.319 Saltbr-in 2.715 HRD-in -73.65, -40.36 65.12, 8.62 in-in-in SNCiii in-in ActLoopNT-in 2.874 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.77, 173.49 APE9-dihe-na 70.21, 177.5 APE8-dihe-in -110.25, 140.72 APE8-rot-in 310.64 APE67-dihe-in -61.7, -20.77 -30.8, -60.11 APE12-dist-in 12.649 APE11-dist-in 10.499 APE10-dist-in 6.199 APE9-dist-in 2.948 None None None XRAY 1.89 0.214 0.263 X 339 319 5 0 0 0 [[40, 325]] 1.0 5yf9 CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
5YWMX 7 329 350.0 NIO:403 Type1 Active DFGin 7.404 16.019 BLAminus -123.21, -176.41 54.46, 76.29 -96.72, 23.28 298.12, 81.76 -77.51, -13.54 in-in in 9.387 Saltbr-in 2.599 HRD-in -75.02, -47.07 66.38, 11.61 in-in-in SNCiii in-in ActLoopNT-in 2.845 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -111.96, 178.56 APE9-dihe-na 63.18, 172.28 APE8-dihe-in -91.07, 141.04 APE8-rot-in 301.46 APE67-dihe-in -66.16, -20.07 -36.63, -51.01 APE12-dist-in 12.942 APE11-dist-in 11.12 APE10-dist-in 6.107 APE9-dist-in 3.168 None None None XRAY 1.939 0.195 0.243 X 339 313 10 0 0 0 [[40, 325]] 1.0 5ywm CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
3OFMA 8 332 350.0 4B0:351 Type1 Active DFGin 7.452 16.214 BLAminus -111.73, -178.5 48.98, 84.52 -96.71, 22.14 295.85, 79.54 -71.26, -18.63 in-in in 9.309 Saltbr-in 2.784 HRD-in -77.02, -48.96 71.36, 6.93 in-in-in SNCiii in-in ActLoopNT-in 2.917 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.3, 168.15 APE9-dihe-na 65.56, 166.69 APE8-dihe-in -96.6, 149.91 APE8-rot-in 302.53 APE67-dihe-in -71.5, -16.65 -41.01, -49.45 APE12-dist-in 12.792 APE11-dist-in 10.445 APE10-dist-in 6.343 APE9-dist-in 3.114 C336S None None XRAY 2.0 0.174 0.207 A 350 325 0 0 0 0 [[40, 325]] 1.0 3ofm CMGC_CSNK2A2_HUMAN CMGC 9e-70 241.1 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
7ATVA 7 334 350.0 RXE:402 Type1 Active DFGin 7.46 15.946 BLAminus -110.8, 177.73 57.78, 76.33 -89.42, 16.94 297.63, 80.21 -70.51, -16.33 in-in in 9.219 Saltbr-in 2.704 HRD-in -73.1, -49.16 71.88, 9.81 in-in-in SNCiii in-in ActLoopNT-in 2.879 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -140.3, 173.64 APE9-dihe-na 61.73, 176.0 APE8-dihe-in -106.82, 144.66 APE8-rot-in 297.53 APE67-dihe-in -67.56, -15.36 -35.81, -58.88 APE12-dist-in 12.735 APE11-dist-in 10.325 APE10-dist-in 6.295 APE9-dist-in 3.012 None None None XRAY 0.98 0.127 0.141 A 364 328 0 0 0 0 [[40, 325]] 1.0 7atv CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
5M4UA 3 334 350.0 7FC:401 Type1 Active DFGin 7.414 16.262 BLAminus -118.78, -178.07 56.43, 80.45 -98.67, 21.05 300.0, 79.38 -67.96, -17.01 in-in in 9.625 Saltbr-in 2.683 HRD-in -74.86, -49.98 70.48, 15.71 in-in-in SNCiii in-in ActLoopNT-in 2.906 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.69, 177.81 APE9-dihe-na 58.81, -177.94 APE8-dihe-in -109.11, 145.32 APE8-rot-in 300.49 APE67-dihe-in -63.69, -18.1 -40.15, -54.29 APE12-dist-in 12.662 APE11-dist-in 10.478 APE10-dist-in 6.186 APE9-dist-in 3.085 D39G,C336S None None XRAY 2.195 0.172 0.214 A 364 332 0 0 0 0 [[40, 325]] 1.0 5m4u CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
5M56B 6 333 350.0 7FC:401 Type1 Active DFGin 7.384 16.303 BLAminus -120.64, -176.02 56.32, 79.52 -99.13, 22.7 296.56, 82.07 -72.78, -19.23 in-in in 9.425 Saltbr-in 2.93 HRD-in -72.23, -49.25 70.06, 13.52 in-in-in SNCiii in-in ActLoopNT-in 2.836 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.49, 171.8 APE9-dihe-na 63.87, 165.28 APE8-dihe-in -84.11, 148.39 APE8-rot-in 295.71 APE67-dihe-in -65.89, -15.75 -47.46, -50.0 APE12-dist-in 12.534 APE11-dist-in 10.407 APE10-dist-in 6.012 APE9-dist-in 3.213 D39G,C336S None None XRAY 2.237 0.165 0.206 B 364 328 0 0 0 0 [[40, 325]] 1.0 5m56 CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
6HMDA 7 334 350.0 GDW:403 Type1 Active DFGin 7.091 15.527 BLAminus -115.45, -178.48 55.42, 77.02 -88.78, 16.86 295.51, 83.08 -68.15, -19.85 in-in in 8.785 Saltbr-in 2.614 HRD-in -78.84, -45.33 68.66, 12.66 in-in-in SNCiii in-in ActLoopNT-in 2.679 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.74, 175.88 APE9-dihe-na 59.03, 175.11 APE8-dihe-in -110.15, 141.73 APE8-rot-in 305.14 APE67-dihe-in -69.85, -13.59 -35.34, -52.83 APE12-dist-in 12.219 APE11-dist-in 9.852 APE10-dist-in 5.913 APE9-dist-in 2.805 C336S None None XRAY 1.0 0.15 0.172 A 365 328 0 0 0 0 [[40, 325]] 1.0 6hmd CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9R5BA 7 333 350.0 A1JCY:401,A1JCY:402 Type1,Allosteric Active DFGin 7.365 16.017 BLAminus -111.36, 179.73 56.2, 77.6 -91.43, 16.96 296.06, 81.16 -73.28, -16.05 in-in in 9.221 Saltbr-in 2.753 HRD-in -73.25, -50.02 71.43, 10.71 in-in-in SNCiii in-in ActLoopNT-in 2.912 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.13, 174.19 APE9-dihe-na 61.47, 174.82 APE8-dihe-in -106.67, 145.22 APE8-rot-in 298.06 APE67-dihe-in -70.26, -13.87 -37.49, -54.66 APE12-dist-in 12.632 APE11-dist-in 10.23 APE10-dist-in 6.17 APE9-dist-in 3.02 C336S None None XRAY 1.09 0.152 0.168 A 364 327 0 0 0 0 [[40, 325]] 1.0 9r5b CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9IHGA 7 333 350.0 SYA:401,SYA:402 Type1,Allosteric Active DFGin 7.406 16.078 BLAminus -114.88, 179.32 57.68, 76.3 -89.4, 14.66 294.43, 83.22 -68.21, -18.97 in-in in 9.168 Saltbr-in 2.756 HRD-in -72.93, -51.52 74.63, 7.13 in-in-in SNCiii in-in ActLoopNT-in 2.899 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.37, 169.41 APE9-dihe-na 65.74, 167.91 APE8-dihe-in -99.86, 143.25 APE8-rot-in 303.68 APE67-dihe-in -68.14, -14.74 -33.99, -55.67 APE12-dist-in 12.75 APE11-dist-in 10.328 APE10-dist-in 6.229 APE9-dist-in 3.15 C336S None None XRAY 1.08 0.134 0.157 A 370 327 0 0 0 0 [[40, 325]] 1.0 9ihg CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
8QCGA 7 330 350.0 ANP:401 ATPlike Inactive DFGin 7.292 16.406 BLAminus -116.12, -179.5 60.93, 75.12 -92.44, 17.38 295.14, 82.0 -69.37, -19.53 in-out in 9.997 Saltbr-out 4.596 HRD-in -74.12, -49.68 72.07, 8.96 out-in-in SNCoii in-in ActLoopNT-in 2.89 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.46, 172.69 APE9-dihe-na 61.42, 170.02 APE8-dihe-in -97.67, 147.66 APE8-rot-in 300.74 APE67-dihe-in -69.16, -14.55 -36.76, -56.59 APE12-dist-in 12.627 APE11-dist-in 10.181 APE10-dist-in 6.131 APE9-dist-in 3.12 C336S None None XRAY 1.04 0.151 0.17 A 364 324 0 0 0 0 [[40, 325]] 1.0 8qcg CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
8Q77A 7 334 350.0 LN3:401,LN3:402 Allosteric,Type1 Inactive DFGin 7.558 16.208 BLAminus -117.42, 174.9 60.57, 78.88 -90.71, 13.92 298.94, 77.03 -68.61, -18.21 in-in in 9.373 Saltbr-in 2.786 HRD-in -74.63, -49.77 75.08, 6.76 in-in-out SNCiio in-out ActLoopNT-in 2.843 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -135.72, 163.76 APE9-dihe-na 71.65, 153.07 APE8-dihe-in -69.0, 144.38 APE8-rot-out 156.78 APE67-dihe-in -68.47, -18.09 -39.0, -51.27 APE12-dist-in 12.432 APE11-dist-in 10.038 APE10-dist-in 6.088 APE9-dist-in 3.351 C336S None None XRAY 1.255 0.12 0.157 A 364 328 0 0 0 0 [[40, 325]] 1.0 8q77 CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
8QBUA 6 333 350.0 42J:404,3NG:405 Allosteric,Type1 Inactive DFGin 7.481 16.117 BLAminus -115.34, 177.54 56.37, 76.99 -87.29, 16.84 296.65, 81.34 -70.83, -16.25 in-in in 9.243 Saltbr-in 2.767 HRD-in -74.29, -50.68 73.5, 10.15 in-in-out SNCiio in-out ActLoopNT-in 2.839 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -134.98, 166.78 APE9-dihe-na 65.99, 156.92 APE8-dihe-in -70.01, 146.12 APE8-rot-out 159.04 APE67-dihe-in -73.31, -10.45 -44.42, -45.9 APE12-dist-in 12.462 APE11-dist-in 10.009 APE10-dist-in 6.107 APE9-dist-in 3.241 C336S None None XRAY 1.09 0.16 0.179 A 364 328 0 0 0 0 [[40, 325]] 1.0 8qbu CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9IHIA 7 333 350.0 SY4:401,3NG:402 Allosteric,Type1 Inactive DFGin 7.415 16.026 BLAminus -114.42, 178.99 58.97, 77.48 -92.68, 17.89 295.72, 83.62 -70.78, -17.6 in-in in 9.166 Saltbr-in 2.815 HRD-in -75.11, -48.36 72.21, 10.05 in-in-out SNCiio in-out ActLoopNT-in 2.841 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.76, 169.32 APE9-dihe-na 65.88, 158.62 APE8-dihe-in -76.33, 145.23 APE8-rot-out 154.92 APE67-dihe-in -68.36, -16.5 -40.48, -52.03 APE12-dist-in 12.783 APE11-dist-in 10.506 APE10-dist-in 6.283 APE9-dist-in 3.236 C336S None None XRAY 1.23 0.136 0.166 A 370 327 0 0 0 0 [[40, 325]] 1.0 9ihi CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9Q9BA 7 333 350.0 VN9:401,3NG:402 Allosteric,Type1 Inactive DFGin 7.47 16.135 BLAminus -114.78, -178.63 52.36, 80.6 -90.66, 23.03 297.12, 80.84 -72.97, -19.45 in-in in 9.164 Saltbr-in 2.851 HRD-in -75.12, -49.8 73.87, 8.89 in-in-out SNCiio in-out ActLoopNT-in 2.899 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -131.85, 168.61 APE9-dihe-na 65.18, 157.14 APE8-dihe-in -73.48, 146.48 APE8-rot-out 146.34 APE67-dihe-in -70.57, -17.74 -39.27, -49.01 APE12-dist-in 12.665 APE11-dist-in 10.424 APE10-dist-in 6.226 APE9-dist-in 3.23 C336S None None XRAY 1.84 0.168 0.206 A 370 327 0 0 0 0 [[40, 325]] 1.0 9q9b CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9QB6A 7 333 350.0 RDV:401,3NG:402 Allosteric,Type1 Inactive DFGin 7.4 16.015 BLAminus -116.09, 178.07 58.12, 76.49 -88.07, 15.69 297.72, 81.25 -71.25, -16.82 in-in in 9.094 Saltbr-in 2.784 HRD-in -72.64, -51.36 73.74, 9.54 in-in-out SNCiio in-out ActLoopNT-in 2.862 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.78, 169.18 APE9-dihe-na 62.18, 162.55 APE8-dihe-in -82.53, 146.39 APE8-rot-out 147.47 APE67-dihe-in -70.59, -14.66 -39.2, -52.96 APE12-dist-in 12.702 APE11-dist-in 10.373 APE10-dist-in 6.226 APE9-dist-in 3.212 C336S None None XRAY 1.05 0.127 0.144 A 370 327 0 0 0 0 [[40, 325]] 1.0 9qb6 CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
7AT9A 6 333 350.0 42J:501,4B0:511,42J:512 Allosteric,Type1,Allosteric Inactive DFGin 7.464 16.003 BLAminus -113.43, 178.2 56.27, 78.92 -92.2, 17.57 296.55, 81.41 -69.68, -18.53 in-in in 9.193 Saltbr-in 2.819 HRD-in -73.6, -48.99 71.34, 11.57 in-in-out SNCiio in-out ActLoopNT-in 2.865 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.69, 170.0 APE9-dihe-na 63.51, 159.84 APE8-dihe-in -73.34, 145.57 APE8-rot-out 161.02 APE67-dihe-in -67.92, -15.68 -40.13, -55.96 APE12-dist-in 12.633 APE11-dist-in 10.194 APE10-dist-in 6.197 APE9-dist-in 3.172 None None None XRAY 1.05 0.129 0.15 A 364 328 0 0 0 0 [[40, 325]] 1.0 7at9 CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9QABA 7 333 350.0 RA7:401,3NG:402,RA7:403 Allosteric,Type1,Allosteric Inactive DFGin 7.376 16.117 BLAminus -113.6, 178.31 57.83, 77.52 -90.77, 14.85 296.13, 81.67 -69.28, -17.99 in-in in 9.175 Saltbr-in 2.76 HRD-in -72.54, -50.49 72.75, 9.89 in-in-out SNCiio in-out ActLoopNT-in 2.902 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -130.24, 170.06 APE9-dihe-na 64.96, 162.68 APE8-dihe-in -81.37, 147.07 APE8-rot-out 150.87 APE67-dihe-in -69.81, -15.24 -39.22, -53.5 APE12-dist-in 12.716 APE11-dist-in 10.351 APE10-dist-in 6.227 APE9-dist-in 3.188 C336S None None XRAY 0.95 0.131 0.141 A 370 327 0 0 0 0 [[40, 325]] 1.0 9qab CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
6L20A 8 332 350.0 E3U:401 Type1 Inactive DFGin 7.732 16.139 BLAminus -122.22, -175.25 49.36, 78.01 -95.69, 38.85 306.27, 75.92 -63.83, -30.35 in-in in 9.239 Saltbr-in 3.3 HRD-in -72.72, -54.66 63.2, 7.6 in-in-out SNCiio in-out ActLoopNT-in 2.766 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -127.23, 165.01 APE9-dihe-na 77.38, 167.34 APE8-dihe-in -79.59, 153.41 APE8-rot-out 152.48 APE67-dihe-in -71.98, -18.58 -57.35, -43.28 APE12-dist-in 13.126 APE11-dist-in 10.499 APE10-dist-in 6.221 APE9-dist-in 3.344 None None None XRAY 3.087 0.249 0.326 A 338 313 12 0 0 0 [[40, 325]] 1.0 6l20 CMGC_CSNK2A2_HUMAN CMGC 8e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
6L20D 8 332 350.0 E3U:401 Type1 Inactive DFGin 7.783 16.14 BLAminus -119.12, 175.9 54.47, 95.98 -114.44, 29.85 310.66, 73.61 -62.79, -25.82 in-out in 9.228 Saltbr-out 3.667 HRD-in -65.52, -40.73 71.31, 1.2 out-in-out SNCoio in-out ActLoopNT-in 2.761 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.21, 166.88 APE9-dihe-na 63.41, 160.07 APE8-dihe-in -71.08, 150.21 APE8-rot-out 156.95 APE67-dihe-in -67.3, -20.16 -49.08, -49.57 APE12-dist-in 12.409 APE11-dist-in 10.176 APE10-dist-in 6.011 APE9-dist-in 3.407 None None None XRAY 3.087 0.249 0.326 D 338 313 12 0 0 0 [[40, 325]] 1.0 6l20 CMGC_CSNK2A2_HUMAN CMGC 8e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
7XYHA 8 332 350.0 8BH:401 Type1 Inactive DFGin 7.384 15.748 BLAminus -139.83, -176.19 49.79, 81.52 -98.03, 13.19 299.32, 81.95 -63.63, -9.29 in-in in 9.327 Saltbr-in 2.832 HRD-in -69.95, -50.98 71.14, 20.17 in-in-out SNCiio in-out ActLoopNT-in 2.864 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -125.51, 159.28 APE9-dihe-na 70.32, 153.83 APE8-dihe-in -69.27, 151.96 APE8-rot-out 159.03 APE67-dihe-in -69.4, -17.44 -50.85, -44.24 APE12-dist-in 12.428 APE11-dist-in 9.668 APE10-dist-in 6.175 APE9-dist-in 3.271 None None None XRAY 2.04 0.234 0.282 A 339 325 0 0 0 0 [[40, 325]] 1.0 7xyh CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
7XYHB 8 332 350.0 8BH:401 Type1 Inactive DFGin 7.699 15.833 BLAminus -126.62, 177.56 61.5, 79.6 -101.95, 18.13 297.9, 80.96 -64.39, -6.35 in-in in 9.349 Saltbr-in 2.745 HRD-in -74.34, -46.84 62.89, 12.82 in-in-out SNCiio in-out ActLoopNT-in 2.81 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -134.19, 160.38 APE9-dihe-na 70.25, 159.52 APE8-dihe-in -78.19, 143.2 APE8-rot-out 181.37 APE67-dihe-in -70.32, -14.54 -24.54, -57.04 APE12-dist-in 12.393 APE11-dist-in 10.012 APE10-dist-in 6.084 APE9-dist-in 3.205 None None None XRAY 2.04 0.234 0.282 B 339 325 0 0 0 0 [[40, 325]] 1.0 7xyh CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
5OOIA 5 333 350.0 9YE:401 Type1 Inactive DFGin 7.394 16.141 BLAminus -117.32, -175.13 49.86, 82.31 -92.54, 19.53 293.97, 79.62 -72.32, -15.68 in-in in 9.362 Saltbr-in 2.777 HRD-in -76.11, -47.99 70.0, 7.9 in-in-out SNCiio in-out ActLoopNT-in 2.912 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -127.8, 163.36 APE9-dihe-na 74.48, 156.62 APE8-dihe-in -68.75, 148.83 APE8-rot-out 160.84 APE67-dihe-in -72.35, -15.47 -47.67, -44.26 APE12-dist-in 12.527 APE11-dist-in 10.404 APE10-dist-in 6.122 APE9-dist-in 3.336 C336S None None XRAY 1.998 0.175 0.221 A 364 329 0 0 0 0 [[40, 325]] 1.0 5ooi CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
5OOIB 7 331 350.0 9YE:401 Type1 Inactive DFGin 7.42 16.003 BLAminus -116.85, -175.58 49.67, 80.83 -90.17, 20.03 295.2, 80.51 -72.72, -17.2 in-in in 9.287 Saltbr-in 2.79 HRD-in -76.47, -50.88 70.18, 10.35 in-in-out SNCiio in-out ActLoopNT-in 2.906 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.82, 162.52 APE9-dihe-na 70.73, 155.38 APE8-dihe-in -70.18, 149.2 APE8-rot-out 158.0 APE67-dihe-in -70.73, -15.65 -46.81, -44.12 APE12-dist-in 12.563 APE11-dist-in 10.275 APE10-dist-in 6.202 APE9-dist-in 3.272 C336S None None XRAY 1.998 0.175 0.221 B 364 325 0 0 0 0 [[40, 325]] 1.0 5ooi CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
6HMBA 7 334 350.0 3NG:413 Type1 Inactive DFGin 7.526 16.135 BLAminus -111.55, 174.56 58.24, 78.46 -87.65, 16.17 297.85, 81.04 -69.02, -17.39 in-in in 9.184 Saltbr-in 2.771 HRD-in -73.83, -48.37 71.6, 10.44 in-in-out SNCiio in-out ActLoopNT-in 2.872 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -135.43, 166.43 APE9-dihe-na 65.52, 156.91 APE8-dihe-in -69.62, 146.48 APE8-rot-out 153.38 APE67-dihe-in -70.99, -14.32 -39.92, -51.06 APE12-dist-in 12.572 APE11-dist-in 10.14 APE10-dist-in 6.125 APE9-dist-in 3.269 C336S None None XRAY 1.04 0.135 0.146 A 364 328 0 0 0 0 [[40, 325]] 1.0 6hmb CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
6HMCA 7 333 350.0 FXB:409 Type1 Inactive DFGin 7.484 15.944 BLAminus -113.63, 176.44 57.73, 79.28 -91.48, 17.74 297.31, 81.27 -70.68, -18.72 in-in in 9.16 Saltbr-in 2.731 HRD-in -73.83, -49.11 72.06, 11.42 in-in-out SNCiio in-out ActLoopNT-in 2.857 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -135.54, 169.71 APE9-dihe-na 63.32, 163.11 APE8-dihe-in -83.38, 144.56 APE8-rot-out 152.32 APE67-dihe-in -69.74, -13.64 -38.13, -54.44 APE12-dist-in 12.722 APE11-dist-in 10.359 APE10-dist-in 6.271 APE9-dist-in 3.135 C336S None None XRAY 1.03 0.123 0.136 A 364 327 0 0 0 0 [[40, 325]] 1.0 6hmc CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
6HMQA 7 333 350.0 4B0:415 Type1 Inactive DFGin 7.516 15.897 BLAminus -111.51, 179.46 53.94, 78.75 -91.06, 16.94 297.02, 81.67 -70.65, -17.57 in-in in 9.287 Saltbr-in 2.7 HRD-in -71.74, -48.86 71.13, 9.58 in-in-out SNCiio in-out ActLoopNT-in 2.865 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.74, 167.44 APE9-dihe-na 67.55, 158.31 APE8-dihe-in -74.76, 147.19 APE8-rot-out 151.59 APE67-dihe-in -69.87, -15.26 -38.65, -53.1 APE12-dist-in 12.719 APE11-dist-in 10.372 APE10-dist-in 6.276 APE9-dist-in 3.216 C336S None None XRAY 0.97 0.12 0.132 A 364 327 0 0 0 0 [[40, 325]] 1.0 6hmq CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
6TE2A 7 333 350.0 N4N:401 Type1 Inactive DFGin 7.421 16.061 BLAminus -111.05, 175.8 56.4, 79.66 -88.88, 16.84 297.11, 78.92 -68.29, -19.45 in-in in 9.179 Saltbr-in 2.737 HRD-in -72.08, -49.24 70.76, 10.56 in-in-out SNCiio in-out ActLoopNT-in 2.873 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -135.35, 169.57 APE9-dihe-na 64.14, 158.38 APE8-dihe-in -66.19, 145.41 APE8-rot-out 157.88 APE67-dihe-in -69.6, -15.07 -41.34, -52.47 APE12-dist-in 12.719 APE11-dist-in 10.288 APE10-dist-in 6.229 APE9-dist-in 3.183 C336S None None XRAY 0.922 0.128 0.146 A 364 327 0 0 0 0 [[40, 325]] 1.0 6te2 CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
6TEWA 8 332 350.0 N5Q:401 Type1 Inactive DFGin 7.448 16.034 BLAminus -113.38, 177.77 58.49, 75.16 -86.58, 13.21 300.09, 80.6 -71.98, -13.55 in-in in 9.191 Saltbr-in 2.764 HRD-in -73.42, -50.71 73.31, 9.16 in-in-out SNCiio in-out ActLoopNT-in 2.855 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -131.31, 166.05 APE9-dihe-na 67.84, 155.34 APE8-dihe-in -69.52, 145.77 APE8-rot-out 155.55 APE67-dihe-in -69.47, -12.71 -39.54, -51.77 APE12-dist-in 12.644 APE11-dist-in 10.283 APE10-dist-in 6.214 APE9-dist-in 3.257 C336S None None XRAY 1.082 0.146 0.169 A 364 325 0 0 0 0 [[40, 325]] 1.0 6tew CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
6TGUA 7 333 350.0 N92:401 Type1 Inactive DFGin 7.552 16.026 BLAminus -112.26, 176.73 56.77, 81.01 -91.35, 17.51 296.45, 79.92 -71.68, -16.8 in-in in 9.305 Saltbr-in 2.722 HRD-in -72.82, -48.7 70.26, 12.12 in-in-out SNCiio in-out ActLoopNT-in 2.834 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.89, 165.93 APE9-dihe-na 69.32, 157.2 APE8-dihe-in -71.77, 145.51 APE8-rot-out 156.69 APE67-dihe-in -70.82, -14.46 -40.19, -51.48 APE12-dist-in 12.593 APE11-dist-in 10.174 APE10-dist-in 6.18 APE9-dist-in 3.226 C336S None None XRAY 0.833 0.144 0.167 A 364 327 0 0 0 0 [[40, 325]] 1.0 6tgu CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
7A1BA 7 333 350.0 QXW:401 Type1 Inactive DFGin 7.327 15.884 BLAminus -115.07, -178.02 53.32, 79.29 -92.21, 18.25 295.46, 80.51 -70.04, -17.41 in-in in 9.068 Saltbr-in 2.755 HRD-in -73.66, -51.05 73.02, 12.19 in-in-out SNCiio in-out ActLoopNT-in 2.839 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -134.84, 165.88 APE9-dihe-na 65.99, 155.29 APE8-dihe-in -66.47, 144.14 APE8-rot-out 158.1 APE67-dihe-in -72.39, -14.92 -39.21, -49.13 APE12-dist-in 12.514 APE11-dist-in 10.155 APE10-dist-in 6.126 APE9-dist-in 3.214 C336S None None XRAY 1.287 0.158 0.193 A 364 327 0 0 0 0 [[40, 325]] 1.0 7a1b CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
7A1ZA 7 334 350.0 QWN:401 Type1 Inactive DFGin 7.312 15.896 BLAminus -116.55, -179.0 52.86, 77.15 -87.42, 15.76 295.79, 82.41 -71.1, -20.14 in-in in 9.118 Saltbr-in 2.742 HRD-in -73.36, -49.56 72.51, 9.81 in-in-out SNCiio in-out ActLoopNT-in 2.863 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.57, 169.23 APE9-dihe-na 63.17, 159.93 APE8-dihe-in -69.83, 147.92 APE8-rot-out 159.64 APE67-dihe-in -69.01, -16.02 -43.66, -52.53 APE12-dist-in 12.616 APE11-dist-in 10.202 APE10-dist-in 6.207 APE9-dist-in 3.183 None None None XRAY 1.024 0.135 0.147 A 364 328 0 0 0 0 [[40, 325]] 1.0 7a1z CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
7A22A 6 333 350.0 QWW:402 Type1 Inactive DFGin 7.492 16.044 BLAminus -109.78, 176.65 59.74, 75.57 -89.61, 15.1 296.52, 81.12 -70.26, -18.33 in-in in 9.319 Saltbr-in 2.717 HRD-in -73.24, -49.68 72.33, 11.09 in-in-out SNCiio in-out ActLoopNT-in 2.867 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.67, 168.35 APE9-dihe-na 65.98, 155.42 APE8-dihe-in -69.68, 147.26 APE8-rot-out 153.84 APE67-dihe-in -70.15, -15.96 -40.75, -51.45 APE12-dist-in 12.577 APE11-dist-in 10.137 APE10-dist-in 6.159 APE9-dist-in 3.273 None None None XRAY 1.01 0.138 0.166 A 364 328 0 0 0 0 [[40, 325]] 1.0 7a22 CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
7A2HA 7 331 350.0 QX2:401 Type1 Inactive DFGin 7.455 15.919 BLAminus -112.63, 178.67 55.25, 78.15 -89.38, 17.48 296.64, 81.25 -70.47, -18.74 in-in in 9.252 Saltbr-in 2.72 HRD-in -73.22, -50.01 71.53, 12.72 in-in-out SNCiio in-out ActLoopNT-in 2.884 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -135.32, 172.31 APE9-dihe-na 60.65, 166.53 APE8-dihe-in -82.84, 147.93 APE8-rot-out 156.9 APE67-dihe-in -69.19, -14.65 -40.46, -56.2 APE12-dist-in 12.648 APE11-dist-in 10.22 APE10-dist-in 6.217 APE9-dist-in 3.094 None None None XRAY 1.01 0.143 0.149 A 364 325 0 0 0 0 [[40, 325]] 1.0 7a2h CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
8Q9SA 7 333 350.0 QBE:401 Type1 Inactive DFGin 7.562 16.186 BLAminus -112.11, 177.67 54.72, 78.76 -89.62, 18.88 296.03, 82.59 -69.97, -18.03 in-in in 9.052 Saltbr-in 2.854 HRD-in -74.44, -49.67 70.19, 11.37 in-in-out SNCiio in-out ActLoopNT-in 2.877 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.65, 169.16 APE9-dihe-na 66.75, 157.23 APE8-dihe-in -72.24, 148.68 APE8-rot-out 154.8 APE67-dihe-in -70.93, -15.32 -42.93, -49.67 APE12-dist-in 12.643 APE11-dist-in 10.326 APE10-dist-in 6.164 APE9-dist-in 3.273 C336S None None XRAY 1.352 0.137 0.169 A 364 327 0 0 0 0 [[40, 325]] 1.0 8q9s CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
8QCDA 7 333 350.0 TBS:402 Type1 Inactive DFGin 7.384 16.126 BLAminus -114.5, 177.89 62.48, 71.57 -90.43, 15.0 296.22, 81.56 -72.45, -14.89 in-in in 9.456 Saltbr-in 2.787 HRD-in -74.09, -49.74 73.57, 10.6 in-in-out SNCiio in-out ActLoopNT-in 2.834 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -136.12, 167.72 APE9-dihe-na 66.59, 156.6 APE8-dihe-in -73.54, 148.52 APE8-rot-out 150.56 APE67-dihe-in -71.43, -15.51 -42.4, -50.04 APE12-dist-in 12.556 APE11-dist-in 10.11 APE10-dist-in 6.138 APE9-dist-in 3.237 C336S None None XRAY 1.03 0.144 0.156 A 364 327 0 0 0 0 [[40, 325]] 1.0 8qcd CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
8QF1A 7 329 350.0 GNP:401 Type1 Inactive DFGin 7.466 16.288 BLAminus -114.86, -178.48 60.39, 75.92 -94.77, 22.65 297.03, 83.05 -72.96, -19.62 in-in in 9.607 Saltbr-in 2.954 HRD-in -74.34, -50.7 74.96, 8.25 in-in-out SNCiio in-out ActLoopNT-in 2.923 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.96, 167.78 APE9-dihe-na 70.02, 160.85 APE8-dihe-in -83.43, 149.5 APE8-rot-out 162.15 APE67-dihe-in -65.8, -15.89 -45.17, -53.3 APE12-dist-in 12.699 APE11-dist-in 10.346 APE10-dist-in 6.16 APE9-dist-in 3.192 C336S None None XRAY 1.32 0.214 0.232 A 364 323 0 0 0 0 [[40, 325]] 1.0 8qf1 CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9FBIA 7 333 350.0 NIO:401 Type1 Inactive DFGin 7.398 16.126 BLAminus -117.51, 178.09 54.8, 75.35 -88.6, 16.43 294.32, 81.79 -66.23, -19.3 in-in in 9.236 Saltbr-in 2.845 HRD-in -76.16, -47.39 73.52, 9.76 in-in-out SNCiio in-out ActLoopNT-in 2.892 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.37, 166.15 APE9-dihe-na 70.34, 154.33 APE8-dihe-in -71.36, 149.29 APE8-rot-out 153.93 APE67-dihe-in -72.01, -15.91 -47.59, -45.82 APE12-dist-in 12.469 APE11-dist-in 10.094 APE10-dist-in 6.031 APE9-dist-in 3.362 C336S None None XRAY 1.161 0.146 0.185 A 364 327 0 0 0 0 [[40, 325]] 1.0 9fbi CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9FBIB 5 333 350.0 NIO:401 Type1 Inactive DFGin 7.471 16.3 BLAminus -116.61, 178.26 54.58, 80.03 -91.17, 14.79 296.76, 82.15 -70.7, -15.45 in-in in 9.643 Saltbr-in 2.697 HRD-in -74.94, -47.04 69.95, 13.58 in-in-out SNCiio in-out ActLoopNT-in 2.872 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -136.62, 165.93 APE9-dihe-na 67.12, 156.73 APE8-dihe-in -70.88, 146.98 APE8-rot-out 150.31 APE67-dihe-in -70.99, -16.75 -44.95, -47.09 APE12-dist-in 12.635 APE11-dist-in 10.43 APE10-dist-in 6.209 APE9-dist-in 3.336 C336S None None XRAY 1.161 0.146 0.185 B 364 329 0 0 0 0 [[40, 325]] 1.0 9fbi CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9GXYA 7 333 350.0 A1IKB:401 Type1 Inactive DFGin 7.52 16.131 BLAminus -109.28, 174.99 57.45, 78.77 -89.21, 16.87 296.94, 82.45 -70.07, -17.54 in-in in 9.251 Saltbr-in 2.768 HRD-in -74.35, -49.25 74.22, 9.99 in-in-out SNCiio in-out ActLoopNT-in 2.857 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.85, 167.52 APE9-dihe-na 67.21, 153.72 APE8-dihe-in -71.12, 145.73 APE8-rot-out 156.37 APE67-dihe-in -72.51, -16.52 -40.49, -47.9 APE12-dist-in 12.608 APE11-dist-in 10.214 APE10-dist-in 6.195 APE9-dist-in 3.297 C336S None None XRAY 1.16 0.161 0.178 A 364 327 0 0 0 0 [[40, 325]] 1.0 9gxy CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9H96A 7 333 350.0 A1ITG:402 Type1 Inactive DFGin 7.377 16.005 BLAminus -114.22, -178.12 57.34, 74.65 -89.54, 12.65 295.7, 85.87 -70.13, -16.33 in-in in 9.213 Saltbr-in 2.792 HRD-in -73.4, -48.91 72.8, 11.83 in-in-out SNCiio in-out ActLoopNT-in 2.838 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.4, 169.21 APE9-dihe-na 64.47, 158.05 APE8-dihe-in -82.79, 147.55 APE8-rot-out 81.98 APE67-dihe-in -74.05, -13.74 -38.35, -50.65 APE12-dist-in 12.553 APE11-dist-in 10.136 APE10-dist-in 6.175 APE9-dist-in 3.202 C336S None None XRAY 1.04 0.173 0.186 A 364 327 0 0 0 0 [[40, 325]] 1.0 9h96 CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9R57A 7 334 350.0 7M0:401 Type1 Inactive DFGin 7.314 15.807 BLAminus -117.79, 179.38 55.53, 79.18 -90.13, 13.15 296.08, 81.93 -68.23, -17.94 in-in in 9.094 Saltbr-in 2.752 HRD-in -73.03, -49.59 68.72, 13.27 in-in-out SNCiio in-out ActLoopNT-in 2.889 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.7, 168.76 APE9-dihe-na 64.02, 159.35 APE8-dihe-in -72.38, 147.39 APE8-rot-out 152.37 APE67-dihe-in -71.68, -13.05 -42.66, -49.27 APE12-dist-in 12.551 APE11-dist-in 10.15 APE10-dist-in 6.154 APE9-dist-in 3.205 C336S None None XRAY 1.1 0.131 0.15 A 364 328 0 0 0 0 [[40, 325]] 1.0 9r57 CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9R5DA 7 334 350.0 A1JC0:406 Type1 Inactive DFGin 7.397 15.991 BLAminus -112.64, 177.28 54.75, 80.13 -91.2, 16.14 298.04, 79.89 -68.67, -15.46 in-in in 9.155 Saltbr-in 2.785 HRD-in -70.54, -55.64 77.27, 10.9 in-in-out SNCiio in-out ActLoopNT-in 2.893 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.81, 166.64 APE9-dihe-na 65.63, 157.17 APE8-dihe-in -69.71, 147.08 APE8-rot-out 154.67 APE67-dihe-in -68.42, -16.02 -40.11, -53.54 APE12-dist-in 12.649 APE11-dist-in 10.201 APE10-dist-in 6.191 APE9-dist-in 3.338 C336S None None XRAY 1.02 0.172 0.193 A 364 328 0 0 0 0 [[40, 325]] 1.0 9r5d CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9R5FA 6 334 350.0 A1JCX:401 Type1 Inactive DFGin 7.35 15.905 BLAminus -117.44, 178.99 56.69, 78.93 -92.83, 18.1 296.95, 81.34 -70.97, -17.8 in-in in 9.203 Saltbr-in 2.792 HRD-in -75.16, -48.41 71.64, 9.51 in-in-out SNCiio in-out ActLoopNT-in 2.855 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -135.8, 164.78 APE9-dihe-na 69.96, 156.03 APE8-dihe-in -69.35, 144.23 APE8-rot-out 157.94 APE67-dihe-in -69.64, -14.56 -36.99, -53.5 APE12-dist-in 12.569 APE11-dist-in 10.151 APE10-dist-in 6.146 APE9-dist-in 3.236 C336S None None XRAY 1.19 0.128 0.155 A 364 329 0 0 0 0 [[40, 325]] 1.0 9r5f CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
5M56A 2 332 350.0 7FC:401 Type1 Inactive DFGin 7.484 16.163 BLAminus -120.51, -175.94 56.7, 79.26 -99.94, 22.01 296.38, 82.8 -72.58, -18.8 in-in in 9.424 Saltbr-in 2.815 HRD-in -72.47, -50.26 70.15, 13.52 in-in-out SNCiio in-out ActLoopNT-in 2.854 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -131.02, 171.03 APE9-dihe-na 64.0, 165.13 APE8-dihe-in -83.29, 148.42 APE8-rot-out 157.63 APE67-dihe-in -65.78, -16.01 -46.77, -49.28 APE12-dist-in 12.506 APE11-dist-in 10.259 APE10-dist-in 6.034 APE9-dist-in 3.241 D39G,C336S None None XRAY 2.237 0.165 0.206 A 364 331 0 0 0 0 [[40, 325]] 1.0 5m56 CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9Q8QA 7 333 350.0 A1I4N:401 Type1 Inactive DFGin 7.435 16.148 BLAminus -112.68, 177.57 58.61, 78.98 -92.73, 15.92 297.62, 79.91 -72.06, -16.96 in-in in 9.34 Saltbr-in 2.806 HRD-in -74.27, -50.0 73.78, 9.25 in-in-out SNCiio in-out ActLoopNT-in 2.85 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.21, 172.35 APE9-dihe-na 59.23, 162.09 APE8-dihe-in -80.22, 145.17 APE8-rot-out 152.48 APE67-dihe-in -71.89, -13.6 -38.8, -51.77 APE12-dist-in 12.709 APE11-dist-in 10.31 APE10-dist-in 6.23 APE9-dist-in 3.195 C336S None None XRAY 0.98 0.148 0.179 A 370 327 0 0 0 0 [[40, 325]] 1.0 9q8q CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9Q9CA 7 334 350.0 R9D:401 Type1 Inactive DFGin 7.382 16.051 BLAminus -115.41, -178.92 55.54, 79.61 -92.68, 21.11 295.96, 82.33 -72.43, -17.63 in-in in 9.279 Saltbr-in 2.769 HRD-in -77.12, -49.51 73.81, 10.58 in-in-out SNCiio in-out ActLoopNT-in 2.923 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.05, 167.7 APE9-dihe-na 65.8, 158.52 APE8-dihe-in -75.93, 148.76 APE8-rot-out 142.61 APE67-dihe-in -68.36, -15.2 -41.25, -53.72 APE12-dist-in 12.706 APE11-dist-in 10.443 APE10-dist-in 6.22 APE9-dist-in 3.171 C336S None None XRAY 1.66 0.189 0.223 A 370 328 0 0 0 0 [[40, 325]] 1.0 9q9c CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9QAKA 7 333 350.0 A1I5I:401 Type1 Inactive DFGin 7.409 16.124 BLAminus -112.6, 179.42 55.7, 76.11 -85.75, 16.58 297.35, 81.8 -69.57, -20.03 in-in in 9.206 Saltbr-in 2.746 HRD-in -73.81, -50.84 74.7, 9.74 in-in-out SNCiio in-out ActLoopNT-in 2.855 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -130.0, 170.78 APE9-dihe-na 62.74, 160.85 APE8-dihe-in -81.27, 148.15 APE8-rot-out 149.99 APE67-dihe-in -71.47, -12.75 -42.8, -50.68 APE12-dist-in 12.76 APE11-dist-in 10.41 APE10-dist-in 6.292 APE9-dist-in 3.214 C336S None None XRAY 0.98 0.148 0.175 A 370 327 0 0 0 0 [[40, 325]] 1.0 9qak CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9QB0A 7 333 350.0 U8X:401 Type1 Inactive DFGin 7.345 16.011 BLAminus -113.24, -179.77 61.72, 72.14 -90.08, 15.6 294.29, 83.61 -71.01, -17.3 in-in in 9.195 Saltbr-in 2.76 HRD-in -73.69, -49.59 74.02, 8.45 in-in-out SNCiio in-out ActLoopNT-in 2.868 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -128.71, 171.25 APE9-dihe-na 61.16, 162.09 APE8-dihe-in -81.48, 146.71 APE8-rot-out 153.91 APE67-dihe-in -69.1, -14.07 -38.93, -54.07 APE12-dist-in 12.732 APE11-dist-in 10.348 APE10-dist-in 6.255 APE9-dist-in 3.22 C336S None None XRAY 1.01 0.14 0.156 A 370 327 0 0 0 0 [[40, 325]] 1.0 9qb0 CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9HK5A 7 334 350.0 3NG:402 Type1 Inactive DFGin 7.542 16.208 BLAminus -114.65, -179.29 53.64, 80.01 -92.35, 20.62 296.39, 82.42 -74.28, -17.08 in-in in 9.271 Saltbr-in 2.826 HRD-in -73.22, -49.09 72.9, 4.28 in-in-out SNCiio in-out ActLoopNT-in 2.899 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -134.78, 167.23 APE9-dihe-na 62.78, 157.39 APE8-dihe-in -75.16, 149.06 APE8-rot-out 147.29 APE67-dihe-in -68.84, -16.32 -43.13, -50.25 APE12-dist-in 12.694 APE11-dist-in 10.358 APE10-dist-in 6.315 APE9-dist-in 3.288 P32V,V83I,T101I,C336S None None XRAY 1.491 0.175 0.204 A 364 328 0 0 0 0 [[40, 325]] 1.0 9hk5 CMGC_CSNK2A2_HUMAN CMGC 3.1e-70 242.7 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9Q9AA 7 333 350.0 3NG:401,A1I4V:402 Type1,Allosteric Inactive DFGin 7.397 16.171 BLAminus -114.27, 179.87 56.61, 76.76 -86.69, 17.58 298.08, 81.74 -71.41, -19.01 in-in in 9.247 Saltbr-in 2.776 HRD-in -75.92, -48.72 71.51, 10.14 in-in-out SNCiio in-out ActLoopNT-in 2.902 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -131.5, 165.78 APE9-dihe-na 68.3, 154.64 APE8-dihe-in -67.27, 146.08 APE8-rot-out 156.93 APE67-dihe-in -69.44, -15.07 -43.26, -49.96 APE12-dist-in 12.724 APE11-dist-in 10.389 APE10-dist-in 6.234 APE9-dist-in 3.275 C336S None None XRAY 1.03 0.147 0.156 A 370 327 0 0 0 0 [[40, 325]] 1.0 9q9a CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9Q9DA 7 332 350.0 3NG:401,R9G:402 Type1,Allosteric Inactive DFGin 7.413 16.113 BLAminus -111.11, 176.5 58.97, 76.86 -90.38, 17.87 296.15, 81.91 -69.6, -18.64 in-in in 9.215 Saltbr-in 2.79 HRD-in -72.74, -49.53 71.25, 10.86 in-in-out SNCiio in-out ActLoopNT-in 2.9 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -129.74, 169.32 APE9-dihe-na 66.15, 161.19 APE8-dihe-in -81.94, 147.26 APE8-rot-out 152.61 APE67-dihe-in -69.62, -15.68 -40.15, -53.5 APE12-dist-in 12.735 APE11-dist-in 10.379 APE10-dist-in 6.221 APE9-dist-in 3.183 C336S None None XRAY 0.89 0.148 0.159 A 370 326 0 0 0 0 [[40, 325]] 1.0 9q9d CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9QAGA 7 333 350.0 3NG:401,RBJ:402 Type1,Allosteric Inactive DFGin 7.402 16.146 BLAminus -113.78, 178.8 55.06, 77.97 -89.73, 16.81 296.32, 81.5 -70.74, -16.11 in-in in 9.239 Saltbr-in 2.765 HRD-in -72.83, -48.69 70.11, 10.59 in-in-out SNCiio in-out ActLoopNT-in 2.868 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.87, 167.19 APE9-dihe-na 64.82, 157.5 APE8-dihe-in -76.42, 146.88 APE8-rot-out 148.1 APE67-dihe-in -71.68, -14.1 -39.59, -52.28 APE12-dist-in 12.68 APE11-dist-in 10.313 APE10-dist-in 6.249 APE9-dist-in 3.264 C336S None None XRAY 1.01 0.136 0.162 A 370 327 0 0 0 0 [[40, 325]] 1.0 9qag CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9Q8CA 7 333 350.0 T9Y:401,T9Y:402,T9Y:403 Type1,Allosteric,Allosteric Inactive DFGin 7.412 16.128 BLAminus -115.35, 178.24 56.83, 76.39 -88.66, 16.23 297.18, 81.04 -70.16, -17.0 in-in in 9.249 Saltbr-in 2.784 HRD-in -74.57, -48.4 71.88, 8.6 in-in-out SNCiio in-out ActLoopNT-in 2.857 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.09, 170.22 APE9-dihe-na 64.38, 165.03 APE8-dihe-in -88.54, 146.5 APE8-rot-out 149.16 APE67-dihe-in -69.16, -17.37 -38.39, -54.09 APE12-dist-in 12.734 APE11-dist-in 10.334 APE10-dist-in 6.247 APE9-dist-in 3.119 C336S None None XRAY 0.9 0.135 0.148 A 370 327 0 0 0 0 [[40, 325]] 1.0 9q8c CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
9Q9GA 7 333 350.0 R9J:401,R9J:402,R9J:403 Type1,Allosteric,Allosteric Inactive DFGin 7.41 16.176 BLAminus -116.31, 174.81 56.6, 81.53 -91.38, 17.7 296.35, 80.59 -69.73, -20.26 in-in in 9.271 Saltbr-in 2.724 HRD-in -73.54, -50.11 73.56, 10.08 in-in-out SNCiio in-out ActLoopNT-in 2.864 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.48, 171.2 APE9-dihe-na 62.47, 166.71 APE8-dihe-in -88.41, 146.96 APE8-rot-out 149.88 APE67-dihe-in -69.36, -14.73 -39.72, -53.83 APE12-dist-in 12.781 APE11-dist-in 10.412 APE10-dist-in 6.302 APE9-dist-in 3.157 C336S None None XRAY 0.94 0.139 0.157 A 370 327 0 0 0 0 [[40, 325]] 1.0 9q9g CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
3E3BX 1 334 350.0 CCK:351 Type1 Inactive DFGin 7.932 16.543 None -60.71, 173.45 58.68, 153.51 -167.77, 24.29 292.11, 94.72 -71.5, -16.51 in-in in 9.967 Saltbr-in 3.176 HRD-in -22.7, -49.66 82.48, 4.05 in-in-in SNCiii in-in ActLoopNT-in 3.536 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -113.37, 167.02 APE9-dihe-na 87.1, -164.84 APE8-dihe-in -118.3, 158.91 APE8-rot-in 284.14 APE67-dihe-in -147.62, -14.08 -66.97, 28.66 APE12-dist-in 13.039 APE11-dist-in 10.823 APE10-dist-in 6.236 APE9-dist-in 3.647 None None None XRAY 3.2 0.268 0.274 X 339 334 0 0 0 0 [[40, 325]] 1.0 3e3b CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'

CMGC_CSNK2A2 (Casein kinase II subunit alpha')

Total number of chains: 70
Active chains: 24
Family: CMGC
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 69 98.6% AF-P19784-K1A
DFGin None 1 1.4% 3E3BX
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CSK22_HUMAN 8QCGB P19784 7 333 350.0 ANP:401 ATPlike Active DFGin 7.314 16.209 BLAminus -113.91, -178.96 61.11, 75.42 -92.86, 17.98 298.38, 79.8 -69.62, -20.0 in-in in 9.436 Saltbr-in 2.83 HRD-in -72.51, -49.6 69.57, 9.93 in-in-in SNCiii in-in ActLoopNT-in 2.828 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.91, 170.94 APE9-dihe-na 61.2, 166.37 APE8-dihe-in -93.43, 149.98 APE8-rot-in 300.62 APE67-dihe-in -69.2, -15.18 -40.28, -54.89 APE12-dist-in 12.657 APE11-dist-in 10.295 APE10-dist-in 6.172 APE9-dist-in 3.11 C336S None None XRAY 1.04 0.151 0.17 B 364 327 0 0 0 0 [[40, 325]] 1.0 8qcg Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9R5CA P19784 7 333 350.0 A1JCZ:401,4B0:402 Allosteric,Type1 Active DFGin 7.352 15.879 BLAminus -111.92, 178.27 56.34, 80.71 -93.81, 15.08 294.28, 82.0 -67.7, -19.18 in-in in 9.075 Saltbr-in 2.756 HRD-in -75.1, -50.02 71.31, 12.54 in-in-in SNCiii in-in ActLoopNT-in 2.854 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.89, 171.36 APE9-dihe-na 64.09, 173.29 APE8-dihe-in -103.87, 145.44 APE8-rot-in 299.19 APE67-dihe-in -66.53, -19.64 -38.47, -55.07 APE12-dist-in 12.613 APE11-dist-in 10.212 APE10-dist-in 6.156 APE9-dist-in 3.065 C336S None None XRAY 1.04 0.145 0.164 A 364 327 0 0 0 0 [[40, 325]] 1.0 9r5c Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN AF-P19784-K1A P19784 32 333 350.0 No_ligand No_ligand Active DFGin 7.369 16.199 BLAminus -121.39, 176.39 61.24, 58.28 -72.82, 13.59 297.09, 82.11 -66.04, -26.53 in-in in 9.369 Saltbr-in 2.693 HRD-in -74.33, -45.67 62.63, 13.83 in-in-in SNCiii in-in ActLoopNT-in 2.899 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -115.93, 172.73 APE9-dihe-na 59.18, 158.52 APE8-dihe-in -78.25, 144.4 APE8-rot-in 303.66 APE67-dihe-in -67.32, -14.94 -43.74, -50.78 APE12-dist-in 12.633 APE11-dist-in 10.459 APE10-dist-in 6.047 APE9-dist-in 3.297 None None None AF2 -1.0 1.0 1.0 A 302 302 0 0 0 0 [[40, 325]] 1.0 AF-P19784-K1 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 5.3e-70 241.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN AF-P19784-K3A P19784 32 333 350.0 No_ligand No_ligand Active DFGin 7.224 16.168 BLAminus -123.84, 175.15 62.02, 53.43 -64.54, 11.55 298.79, 84.22 -66.31, -24.89 in-in in 9.288 Saltbr-in 2.689 HRD-in -77.16, -42.8 61.58, 14.61 in-in-in SNCiii in-in ActLoopNT-in 2.925 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -115.92, 172.28 APE9-dihe-na 57.3, 148.18 APE8-dihe-in -74.15, 142.51 APE8-rot-in 301.25 APE67-dihe-in -68.42, -14.07 -40.82, -53.0 APE12-dist-in 12.443 APE11-dist-in 10.151 APE10-dist-in 6.001 APE9-dist-in 3.256 None None None AF2 -1.0 1.0 1.0 A 302 302 0 0 0 0 [[40, 325]] 1.0 AF-P19784-K3 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 5.3e-70 241.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 8QF1B P19784 7 333 350.0 No_ligand No_ligand Active DFGin 7.389 16.15 BLAminus -120.85, -177.74 54.7, 88.15 -104.97, 18.42 294.01, 82.89 -68.69, -20.02 in-in in 9.509 Saltbr-in 3.045 HRD-in -75.42, -49.34 71.04, 8.42 in-in-in SNCiii in-in ActLoopNT-in 2.833 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.85, 175.43 APE9-dihe-na 63.75, 177.89 APE8-dihe-in -108.49, 146.29 APE8-rot-in 295.14 APE67-dihe-in -65.54, -16.58 -41.79, -51.59 APE12-dist-in 12.784 APE11-dist-in 10.377 APE10-dist-in 6.189 APE9-dist-in 2.983 C336S None None XRAY 1.32 0.214 0.232 B 364 327 0 0 0 0 [[40, 325]] 1.0 8qf1 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 6QY8A P19784 8 330 350.0 041:500 Type1 Active DFGin 7.384 16.141 BLAminus -120.12, 176.92 53.95, 78.53 -91.82, 22.02 295.47, 79.33 -73.46, -14.93 in-in in 9.506 Saltbr-in 2.748 HRD-in -74.68, -55.45 73.72, 15.02 in-in-in SNCiii in-in ActLoopNT-in 2.872 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.61, 171.26 APE9-dihe-na 56.4, 177.65 APE8-dihe-in -106.07, 146.22 APE8-rot-in 310.11 APE67-dihe-in -67.75, -14.94 -42.59, -51.92 APE12-dist-in 12.331 APE11-dist-in 9.826 APE10-dist-in 5.991 APE9-dist-in 3.178 None None None XRAY 1.7 0.265 0.291 A 336 321 2 0 0 0 [[40, 325]] 1.0 6qy8 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 7.8e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 6QY8B P19784 8 332 350.0 041:500 Type1 Active DFGin 7.393 16.185 BLAminus -118.01, 175.97 55.87, 77.94 -91.32, 21.09 292.85, 80.76 -71.72, -13.94 in-in in 9.604 Saltbr-in 2.771 HRD-in -73.14, -53.85 71.23, 15.63 in-in-in SNCiii in-in ActLoopNT-in 2.879 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.98, 172.57 APE9-dihe-na 61.84, 175.34 APE8-dihe-in -104.11, 145.88 APE8-rot-in 310.29 APE67-dihe-in -68.68, -14.13 -40.25, -52.48 APE12-dist-in 12.492 APE11-dist-in 10.014 APE10-dist-in 6.056 APE9-dist-in 3.154 None None None XRAY 1.7 0.265 0.291 B 336 323 2 0 0 0 [[40, 325]] 1.0 6qy8 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 7.8e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 6QY8C P19784 8 332 350.0 041:500 Type1 Active DFGin 7.396 16.108 BLAminus -117.04, 176.75 55.38, 77.75 -90.54, 20.88 296.94, 80.84 -70.87, -18.26 in-in in 9.556 Saltbr-in 2.774 HRD-in -73.1, -54.09 70.1, 18.8 in-in-in SNCiii in-in ActLoopNT-in 2.884 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.13, 171.16 APE9-dihe-na 62.91, 176.48 APE8-dihe-in -108.0, 146.42 APE8-rot-in 311.4 APE67-dihe-in -68.5, -13.94 -43.41, -50.54 APE12-dist-in 12.419 APE11-dist-in 9.882 APE10-dist-in 5.98 APE9-dist-in 3.143 None None None XRAY 1.7 0.265 0.291 C 336 325 0 0 0 0 [[40, 325]] 1.0 6qy8 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 7.8e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 6QY8D P19784 8 332 350.0 041:500 Type1 Active DFGin 7.385 16.098 BLAminus -117.58, 176.73 55.17, 76.49 -91.26, 21.62 297.41, 80.15 -73.81, -12.58 in-in in 9.478 Saltbr-in 2.77 HRD-in -75.19, -54.21 74.19, 15.39 in-in-in SNCiii in-in ActLoopNT-in 2.857 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.38, 170.81 APE9-dihe-na 62.1, 174.51 APE8-dihe-in -104.94, 144.68 APE8-rot-in 310.96 APE67-dihe-in -67.06, -14.14 -40.83, -52.81 APE12-dist-in 12.571 APE11-dist-in 10.099 APE10-dist-in 6.144 APE9-dist-in 3.163 None None None XRAY 1.7 0.265 0.291 D 336 323 2 0 0 0 [[40, 325]] 1.0 6qy8 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 7.8e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 6QY9A P19784 7 335 350.0 JL2:401 Type1 Active DFGin 7.356 16.106 BLAminus -116.84, -178.12 52.4, 77.34 -88.44, 16.74 294.55, 80.65 -68.91, -20.63 in-in in 9.253 Saltbr-in 2.783 HRD-in -74.61, -49.29 71.4, 14.8 in-in-in SNCiii in-in ActLoopNT-in 2.86 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.06, 173.6 APE9-dihe-na 62.78, 178.89 APE8-dihe-in -108.7, 142.76 APE8-rot-in 301.62 APE67-dihe-in -69.55, -13.66 -39.9, -52.14 APE12-dist-in 12.497 APE11-dist-in 10.172 APE10-dist-in 6.187 APE9-dist-in 3.11 None None None XRAY 1.5 0.127 0.165 A 336 329 0 0 0 0 [[40, 325]] 1.0 6qy9 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 7.8e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 6L20G P19784 8 332 350.0 E3U:401 Type1 Active DFGin 7.284 16.005 BLAminus -127.52, -173.82 53.59, 81.78 -99.19, 29.51 292.18, 85.28 -60.52, -51.96 in-in in 9.472 Saltbr-in 3.173 HRD-in -61.14, -61.27 82.07, -26.56 in-in-in SNCiii in-in ActLoopNT-in 2.594 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.99, 171.25 APE9-dihe-na 64.2, 155.75 APE8-dihe-in -86.4, 156.84 APE8-rot-in 302.93 APE67-dihe-in -58.16, -47.73 -52.96, -55.01 APE12-dist-in 12.506 APE11-dist-in 9.924 APE10-dist-in 5.875 APE9-dist-in 3.149 None None None XRAY 3.087 0.249 0.326 G 338 319 6 0 0 0 [[40, 325]] 1.0 6l20 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 8e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 6L20J P19784 8 332 350.0 E3U:401 Type1 Active DFGin 7.46 16.389 BLAminus -136.61, -171.16 54.01, 68.09 -89.26, 14.98 297.06, 81.4 -59.25, -24.06 in-in in 9.903 Saltbr-in 3.253 HRD-in -60.53, -53.7 72.4, -1.96 in-in-in SNCiii in-in ActLoopNT-in 3.327 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -145.22, 173.34 APE9-dihe-na 50.03, -179.69 APE8-dihe-in -96.9, 164.64 APE8-rot-in 296.92 APE67-dihe-in -43.38, -47.79 -57.7, -61.79 APE12-dist-in 12.906 APE11-dist-in 10.476 APE10-dist-in 6.421 APE9-dist-in 2.999 None None None XRAY 3.087 0.249 0.326 J 338 314 11 0 0 0 [[40, 325]] 1.0 6l20 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 8e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 5Y9MA P19784 7 329 350.0 NIO:401 Type1 Active DFGin 7.413 16.17 BLAminus -114.7, 179.98 51.13, 80.68 -91.85, 19.14 294.67, 80.42 -65.77, -17.09 in-in in 9.364 Saltbr-in 2.718 HRD-in -70.56, -47.51 66.93, 6.34 in-in-in SNCiii in-in ActLoopNT-in 2.81 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.58, 175.14 APE9-dihe-na 60.0, -172.23 APE8-dihe-in -119.82, 146.83 APE8-rot-in 298.24 APE67-dihe-in -67.32, -19.61 -42.77, -51.22 APE12-dist-in 12.724 APE11-dist-in 10.493 APE10-dist-in 6.152 APE9-dist-in 3.013 None None None XRAY 2.006 0.173 0.205 A 339 320 3 0 0 0 [[40, 325]] 1.0 5y9m Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 5Y9MX P19784 7 329 350.0 NIO:401 Type1 Active DFGin 7.419 16.296 BLAminus -114.61, -179.34 52.3, 79.76 -91.76, 19.36 295.38, 79.95 -64.7, -18.3 in-in in 9.336 Saltbr-in 2.717 HRD-in -70.29, -48.55 67.93, 5.94 in-in-in SNCiii in-in ActLoopNT-in 2.806 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.82, 175.26 APE9-dihe-na 61.28, -171.63 APE8-dihe-in -117.63, 147.87 APE8-rot-in 296.65 APE67-dihe-in -67.57, -18.73 -43.97, -52.04 APE12-dist-in 12.753 APE11-dist-in 10.798 APE10-dist-in 6.257 APE9-dist-in 3.052 None None None XRAY 2.006 0.173 0.205 X 339 319 4 0 0 0 [[40, 325]] 1.0 5y9m Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 5YF9B P19784 6 329 350.0 NIO:401 Type1 Active DFGin 7.459 16.07 BLAminus -110.95, -179.27 53.65, 80.05 -91.28, 26.14 296.96, 82.34 -75.04, -13.81 in-in in 9.343 Saltbr-in 2.569 HRD-in -67.49, -46.45 66.2, 15.42 in-in-in SNCiii in-in ActLoopNT-in 2.969 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.9, 174.16 APE9-dihe-na 64.72, 177.19 APE8-dihe-in -102.79, 146.68 APE8-rot-in 285.72 APE67-dihe-in -62.8, -17.43 -42.57, -55.43 APE12-dist-in 12.715 APE11-dist-in 10.521 APE10-dist-in 6.167 APE9-dist-in 3.05 None None None XRAY 1.89 0.214 0.263 B 339 319 5 0 0 0 [[40, 325]] 1.0 5yf9 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 5YF9X P19784 6 329 350.0 NIO:401 Type1 Active DFGin 7.455 16.124 BLAminus -110.45, 178.76 52.99, 85.82 -99.51, 23.76 294.09, 79.0 -68.33, -18.31 in-in in 9.319 Saltbr-in 2.715 HRD-in -73.65, -40.36 65.12, 8.62 in-in-in SNCiii in-in ActLoopNT-in 2.874 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.77, 173.49 APE9-dihe-na 70.21, 177.5 APE8-dihe-in -110.25, 140.72 APE8-rot-in 310.64 APE67-dihe-in -61.7, -20.77 -30.8, -60.11 APE12-dist-in 12.649 APE11-dist-in 10.499 APE10-dist-in 6.199 APE9-dist-in 2.948 None None None XRAY 1.89 0.214 0.263 X 339 319 5 0 0 0 [[40, 325]] 1.0 5yf9 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 5YWMX P19784 7 329 350.0 NIO:403 Type1 Active DFGin 7.404 16.019 BLAminus -123.21, -176.41 54.46, 76.29 -96.72, 23.28 298.12, 81.76 -77.51, -13.54 in-in in 9.387 Saltbr-in 2.599 HRD-in -75.02, -47.07 66.38, 11.61 in-in-in SNCiii in-in ActLoopNT-in 2.845 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -111.96, 178.56 APE9-dihe-na 63.18, 172.28 APE8-dihe-in -91.07, 141.04 APE8-rot-in 301.46 APE67-dihe-in -66.16, -20.07 -36.63, -51.01 APE12-dist-in 12.942 APE11-dist-in 11.12 APE10-dist-in 6.107 APE9-dist-in 3.168 None None None XRAY 1.939 0.195 0.243 X 339 313 10 0 0 0 [[40, 325]] 1.0 5ywm Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 3OFMA P19784 8 332 350.0 4B0:351 Type1 Active DFGin 7.452 16.214 BLAminus -111.73, -178.5 48.98, 84.52 -96.71, 22.14 295.85, 79.54 -71.26, -18.63 in-in in 9.309 Saltbr-in 2.784 HRD-in -77.02, -48.96 71.36, 6.93 in-in-in SNCiii in-in ActLoopNT-in 2.917 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.3, 168.15 APE9-dihe-na 65.56, 166.69 APE8-dihe-in -96.6, 149.91 APE8-rot-in 302.53 APE67-dihe-in -71.5, -16.65 -41.01, -49.45 APE12-dist-in 12.792 APE11-dist-in 10.445 APE10-dist-in 6.343 APE9-dist-in 3.114 C336S None None XRAY 2.0 0.174 0.207 A 350 325 0 0 0 0 [[40, 325]] 1.0 3ofm Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 9e-70 241.1 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 7ATVA P19784 7 334 350.0 RXE:402 Type1 Active DFGin 7.46 15.946 BLAminus -110.8, 177.73 57.78, 76.33 -89.42, 16.94 297.63, 80.21 -70.51, -16.33 in-in in 9.219 Saltbr-in 2.704 HRD-in -73.1, -49.16 71.88, 9.81 in-in-in SNCiii in-in ActLoopNT-in 2.879 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -140.3, 173.64 APE9-dihe-na 61.73, 176.0 APE8-dihe-in -106.82, 144.66 APE8-rot-in 297.53 APE67-dihe-in -67.56, -15.36 -35.81, -58.88 APE12-dist-in 12.735 APE11-dist-in 10.325 APE10-dist-in 6.295 APE9-dist-in 3.012 None None None XRAY 0.98 0.127 0.141 A 364 328 0 0 0 0 [[40, 325]] 1.0 7atv Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 5M4UA P19784 3 334 350.0 7FC:401 Type1 Active DFGin 7.414 16.262 BLAminus -118.78, -178.07 56.43, 80.45 -98.67, 21.05 300.0, 79.38 -67.96, -17.01 in-in in 9.625 Saltbr-in 2.683 HRD-in -74.86, -49.98 70.48, 15.71 in-in-in SNCiii in-in ActLoopNT-in 2.906 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.69, 177.81 APE9-dihe-na 58.81, -177.94 APE8-dihe-in -109.11, 145.32 APE8-rot-in 300.49 APE67-dihe-in -63.69, -18.1 -40.15, -54.29 APE12-dist-in 12.662 APE11-dist-in 10.478 APE10-dist-in 6.186 APE9-dist-in 3.085 D39G,C336S None None XRAY 2.195 0.172 0.214 A 364 332 0 0 0 0 [[40, 325]] 1.0 5m4u Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 5M56B P19784 6 333 350.0 7FC:401 Type1 Active DFGin 7.384 16.303 BLAminus -120.64, -176.02 56.32, 79.52 -99.13, 22.7 296.56, 82.07 -72.78, -19.23 in-in in 9.425 Saltbr-in 2.93 HRD-in -72.23, -49.25 70.06, 13.52 in-in-in SNCiii in-in ActLoopNT-in 2.836 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.49, 171.8 APE9-dihe-na 63.87, 165.28 APE8-dihe-in -84.11, 148.39 APE8-rot-in 295.71 APE67-dihe-in -65.89, -15.75 -47.46, -50.0 APE12-dist-in 12.534 APE11-dist-in 10.407 APE10-dist-in 6.012 APE9-dist-in 3.213 D39G,C336S None None XRAY 2.237 0.165 0.206 B 364 328 0 0 0 0 [[40, 325]] 1.0 5m56 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 6HMDA P19784 7 334 350.0 GDW:403 Type1 Active DFGin 7.091 15.527 BLAminus -115.45, -178.48 55.42, 77.02 -88.78, 16.86 295.51, 83.08 -68.15, -19.85 in-in in 8.785 Saltbr-in 2.614 HRD-in -78.84, -45.33 68.66, 12.66 in-in-in SNCiii in-in ActLoopNT-in 2.679 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.74, 175.88 APE9-dihe-na 59.03, 175.11 APE8-dihe-in -110.15, 141.73 APE8-rot-in 305.14 APE67-dihe-in -69.85, -13.59 -35.34, -52.83 APE12-dist-in 12.219 APE11-dist-in 9.852 APE10-dist-in 5.913 APE9-dist-in 2.805 C336S None None XRAY 1.0 0.15 0.172 A 365 328 0 0 0 0 [[40, 325]] 1.0 6hmd Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9R5BA P19784 7 333 350.0 A1JCY:401,A1JCY:402 Type1,Allosteric Active DFGin 7.365 16.017 BLAminus -111.36, 179.73 56.2, 77.6 -91.43, 16.96 296.06, 81.16 -73.28, -16.05 in-in in 9.221 Saltbr-in 2.753 HRD-in -73.25, -50.02 71.43, 10.71 in-in-in SNCiii in-in ActLoopNT-in 2.912 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.13, 174.19 APE9-dihe-na 61.47, 174.82 APE8-dihe-in -106.67, 145.22 APE8-rot-in 298.06 APE67-dihe-in -70.26, -13.87 -37.49, -54.66 APE12-dist-in 12.632 APE11-dist-in 10.23 APE10-dist-in 6.17 APE9-dist-in 3.02 C336S None None XRAY 1.09 0.152 0.168 A 364 327 0 0 0 0 [[40, 325]] 1.0 9r5b Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9IHGA P19784 7 333 350.0 SYA:401,SYA:402 Type1,Allosteric Active DFGin 7.406 16.078 BLAminus -114.88, 179.32 57.68, 76.3 -89.4, 14.66 294.43, 83.22 -68.21, -18.97 in-in in 9.168 Saltbr-in 2.756 HRD-in -72.93, -51.52 74.63, 7.13 in-in-in SNCiii in-in ActLoopNT-in 2.899 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.37, 169.41 APE9-dihe-na 65.74, 167.91 APE8-dihe-in -99.86, 143.25 APE8-rot-in 303.68 APE67-dihe-in -68.14, -14.74 -33.99, -55.67 APE12-dist-in 12.75 APE11-dist-in 10.328 APE10-dist-in 6.229 APE9-dist-in 3.15 C336S None None XRAY 1.08 0.134 0.157 A 370 327 0 0 0 0 [[40, 325]] 1.0 9ihg Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 8QCGA P19784 7 330 350.0 ANP:401 ATPlike Inactive DFGin 7.292 16.406 BLAminus -116.12, -179.5 60.93, 75.12 -92.44, 17.38 295.14, 82.0 -69.37, -19.53 in-out in 9.997 Saltbr-out 4.596 HRD-in -74.12, -49.68 72.07, 8.96 out-in-in SNCoii in-in ActLoopNT-in 2.89 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.46, 172.69 APE9-dihe-na 61.42, 170.02 APE8-dihe-in -97.67, 147.66 APE8-rot-in 300.74 APE67-dihe-in -69.16, -14.55 -36.76, -56.59 APE12-dist-in 12.627 APE11-dist-in 10.181 APE10-dist-in 6.131 APE9-dist-in 3.12 C336S None None XRAY 1.04 0.151 0.17 A 364 324 0 0 0 0 [[40, 325]] 1.0 8qcg Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 8Q77A P19784 7 334 350.0 LN3:401,LN3:402 Allosteric,Type1 Inactive DFGin 7.558 16.208 BLAminus -117.42, 174.9 60.57, 78.88 -90.71, 13.92 298.94, 77.03 -68.61, -18.21 in-in in 9.373 Saltbr-in 2.786 HRD-in -74.63, -49.77 75.08, 6.76 in-in-out SNCiio in-out ActLoopNT-in 2.843 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -135.72, 163.76 APE9-dihe-na 71.65, 153.07 APE8-dihe-in -69.0, 144.38 APE8-rot-out 156.78 APE67-dihe-in -68.47, -18.09 -39.0, -51.27 APE12-dist-in 12.432 APE11-dist-in 10.038 APE10-dist-in 6.088 APE9-dist-in 3.351 C336S None None XRAY 1.255 0.12 0.157 A 364 328 0 0 0 0 [[40, 325]] 1.0 8q77 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 8QBUA P19784 6 333 350.0 42J:404,3NG:405 Allosteric,Type1 Inactive DFGin 7.481 16.117 BLAminus -115.34, 177.54 56.37, 76.99 -87.29, 16.84 296.65, 81.34 -70.83, -16.25 in-in in 9.243 Saltbr-in 2.767 HRD-in -74.29, -50.68 73.5, 10.15 in-in-out SNCiio in-out ActLoopNT-in 2.839 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -134.98, 166.78 APE9-dihe-na 65.99, 156.92 APE8-dihe-in -70.01, 146.12 APE8-rot-out 159.04 APE67-dihe-in -73.31, -10.45 -44.42, -45.9 APE12-dist-in 12.462 APE11-dist-in 10.009 APE10-dist-in 6.107 APE9-dist-in 3.241 C336S None None XRAY 1.09 0.16 0.179 A 364 328 0 0 0 0 [[40, 325]] 1.0 8qbu Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9IHIA P19784 7 333 350.0 SY4:401,3NG:402 Allosteric,Type1 Inactive DFGin 7.415 16.026 BLAminus -114.42, 178.99 58.97, 77.48 -92.68, 17.89 295.72, 83.62 -70.78, -17.6 in-in in 9.166 Saltbr-in 2.815 HRD-in -75.11, -48.36 72.21, 10.05 in-in-out SNCiio in-out ActLoopNT-in 2.841 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.76, 169.32 APE9-dihe-na 65.88, 158.62 APE8-dihe-in -76.33, 145.23 APE8-rot-out 154.92 APE67-dihe-in -68.36, -16.5 -40.48, -52.03 APE12-dist-in 12.783 APE11-dist-in 10.506 APE10-dist-in 6.283 APE9-dist-in 3.236 C336S None None XRAY 1.23 0.136 0.166 A 370 327 0 0 0 0 [[40, 325]] 1.0 9ihi Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9Q9BA P19784 7 333 350.0 VN9:401,3NG:402 Allosteric,Type1 Inactive DFGin 7.47 16.135 BLAminus -114.78, -178.63 52.36, 80.6 -90.66, 23.03 297.12, 80.84 -72.97, -19.45 in-in in 9.164 Saltbr-in 2.851 HRD-in -75.12, -49.8 73.87, 8.89 in-in-out SNCiio in-out ActLoopNT-in 2.899 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -131.85, 168.61 APE9-dihe-na 65.18, 157.14 APE8-dihe-in -73.48, 146.48 APE8-rot-out 146.34 APE67-dihe-in -70.57, -17.74 -39.27, -49.01 APE12-dist-in 12.665 APE11-dist-in 10.424 APE10-dist-in 6.226 APE9-dist-in 3.23 C336S None None XRAY 1.84 0.168 0.206 A 370 327 0 0 0 0 [[40, 325]] 1.0 9q9b Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9QB6A P19784 7 333 350.0 RDV:401,3NG:402 Allosteric,Type1 Inactive DFGin 7.4 16.015 BLAminus -116.09, 178.07 58.12, 76.49 -88.07, 15.69 297.72, 81.25 -71.25, -16.82 in-in in 9.094 Saltbr-in 2.784 HRD-in -72.64, -51.36 73.74, 9.54 in-in-out SNCiio in-out ActLoopNT-in 2.862 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.78, 169.18 APE9-dihe-na 62.18, 162.55 APE8-dihe-in -82.53, 146.39 APE8-rot-out 147.47 APE67-dihe-in -70.59, -14.66 -39.2, -52.96 APE12-dist-in 12.702 APE11-dist-in 10.373 APE10-dist-in 6.226 APE9-dist-in 3.212 C336S None None XRAY 1.05 0.127 0.144 A 370 327 0 0 0 0 [[40, 325]] 1.0 9qb6 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 7AT9A P19784 6 333 350.0 42J:501,4B0:511,42J:512 Allosteric,Type1,Allosteric Inactive DFGin 7.464 16.003 BLAminus -113.43, 178.2 56.27, 78.92 -92.2, 17.57 296.55, 81.41 -69.68, -18.53 in-in in 9.193 Saltbr-in 2.819 HRD-in -73.6, -48.99 71.34, 11.57 in-in-out SNCiio in-out ActLoopNT-in 2.865 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.69, 170.0 APE9-dihe-na 63.51, 159.84 APE8-dihe-in -73.34, 145.57 APE8-rot-out 161.02 APE67-dihe-in -67.92, -15.68 -40.13, -55.96 APE12-dist-in 12.633 APE11-dist-in 10.194 APE10-dist-in 6.197 APE9-dist-in 3.172 None None None XRAY 1.05 0.129 0.15 A 364 328 0 0 0 0 [[40, 325]] 1.0 7at9 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9QABA P19784 7 333 350.0 RA7:401,3NG:402,RA7:403 Allosteric,Type1,Allosteric Inactive DFGin 7.376 16.117 BLAminus -113.6, 178.31 57.83, 77.52 -90.77, 14.85 296.13, 81.67 -69.28, -17.99 in-in in 9.175 Saltbr-in 2.76 HRD-in -72.54, -50.49 72.75, 9.89 in-in-out SNCiio in-out ActLoopNT-in 2.902 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -130.24, 170.06 APE9-dihe-na 64.96, 162.68 APE8-dihe-in -81.37, 147.07 APE8-rot-out 150.87 APE67-dihe-in -69.81, -15.24 -39.22, -53.5 APE12-dist-in 12.716 APE11-dist-in 10.351 APE10-dist-in 6.227 APE9-dist-in 3.188 C336S None None XRAY 0.95 0.131 0.141 A 370 327 0 0 0 0 [[40, 325]] 1.0 9qab Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 6L20A P19784 8 332 350.0 E3U:401 Type1 Inactive DFGin 7.732 16.139 BLAminus -122.22, -175.25 49.36, 78.01 -95.69, 38.85 306.27, 75.92 -63.83, -30.35 in-in in 9.239 Saltbr-in 3.3 HRD-in -72.72, -54.66 63.2, 7.6 in-in-out SNCiio in-out ActLoopNT-in 2.766 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -127.23, 165.01 APE9-dihe-na 77.38, 167.34 APE8-dihe-in -79.59, 153.41 APE8-rot-out 152.48 APE67-dihe-in -71.98, -18.58 -57.35, -43.28 APE12-dist-in 13.126 APE11-dist-in 10.499 APE10-dist-in 6.221 APE9-dist-in 3.344 None None None XRAY 3.087 0.249 0.326 A 338 313 12 0 0 0 [[40, 325]] 1.0 6l20 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 8e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 6L20D P19784 8 332 350.0 E3U:401 Type1 Inactive DFGin 7.783 16.14 BLAminus -119.12, 175.9 54.47, 95.98 -114.44, 29.85 310.66, 73.61 -62.79, -25.82 in-out in 9.228 Saltbr-out 3.667 HRD-in -65.52, -40.73 71.31, 1.2 out-in-out SNCoio in-out ActLoopNT-in 2.761 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.21, 166.88 APE9-dihe-na 63.41, 160.07 APE8-dihe-in -71.08, 150.21 APE8-rot-out 156.95 APE67-dihe-in -67.3, -20.16 -49.08, -49.57 APE12-dist-in 12.409 APE11-dist-in 10.176 APE10-dist-in 6.011 APE9-dist-in 3.407 None None None XRAY 3.087 0.249 0.326 D 338 313 12 0 0 0 [[40, 325]] 1.0 6l20 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 8e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 7XYHA P19784 8 332 350.0 8BH:401 Type1 Inactive DFGin 7.384 15.748 BLAminus -139.83, -176.19 49.79, 81.52 -98.03, 13.19 299.32, 81.95 -63.63, -9.29 in-in in 9.327 Saltbr-in 2.832 HRD-in -69.95, -50.98 71.14, 20.17 in-in-out SNCiio in-out ActLoopNT-in 2.864 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -125.51, 159.28 APE9-dihe-na 70.32, 153.83 APE8-dihe-in -69.27, 151.96 APE8-rot-out 159.03 APE67-dihe-in -69.4, -17.44 -50.85, -44.24 APE12-dist-in 12.428 APE11-dist-in 9.668 APE10-dist-in 6.175 APE9-dist-in 3.271 None None None XRAY 2.04 0.234 0.282 A 339 325 0 0 0 0 [[40, 325]] 1.0 7xyh Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 7XYHB P19784 8 332 350.0 8BH:401 Type1 Inactive DFGin 7.699 15.833 BLAminus -126.62, 177.56 61.5, 79.6 -101.95, 18.13 297.9, 80.96 -64.39, -6.35 in-in in 9.349 Saltbr-in 2.745 HRD-in -74.34, -46.84 62.89, 12.82 in-in-out SNCiio in-out ActLoopNT-in 2.81 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -134.19, 160.38 APE9-dihe-na 70.25, 159.52 APE8-dihe-in -78.19, 143.2 APE8-rot-out 181.37 APE67-dihe-in -70.32, -14.54 -24.54, -57.04 APE12-dist-in 12.393 APE11-dist-in 10.012 APE10-dist-in 6.084 APE9-dist-in 3.205 None None None XRAY 2.04 0.234 0.282 B 339 325 0 0 0 0 [[40, 325]] 1.0 7xyh Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 5OOIA P19784 5 333 350.0 9YE:401 Type1 Inactive DFGin 7.394 16.141 BLAminus -117.32, -175.13 49.86, 82.31 -92.54, 19.53 293.97, 79.62 -72.32, -15.68 in-in in 9.362 Saltbr-in 2.777 HRD-in -76.11, -47.99 70.0, 7.9 in-in-out SNCiio in-out ActLoopNT-in 2.912 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -127.8, 163.36 APE9-dihe-na 74.48, 156.62 APE8-dihe-in -68.75, 148.83 APE8-rot-out 160.84 APE67-dihe-in -72.35, -15.47 -47.67, -44.26 APE12-dist-in 12.527 APE11-dist-in 10.404 APE10-dist-in 6.122 APE9-dist-in 3.336 C336S None None XRAY 1.998 0.175 0.221 A 364 329 0 0 0 0 [[40, 325]] 1.0 5ooi Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 5OOIB P19784 7 331 350.0 9YE:401 Type1 Inactive DFGin 7.42 16.003 BLAminus -116.85, -175.58 49.67, 80.83 -90.17, 20.03 295.2, 80.51 -72.72, -17.2 in-in in 9.287 Saltbr-in 2.79 HRD-in -76.47, -50.88 70.18, 10.35 in-in-out SNCiio in-out ActLoopNT-in 2.906 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.82, 162.52 APE9-dihe-na 70.73, 155.38 APE8-dihe-in -70.18, 149.2 APE8-rot-out 158.0 APE67-dihe-in -70.73, -15.65 -46.81, -44.12 APE12-dist-in 12.563 APE11-dist-in 10.275 APE10-dist-in 6.202 APE9-dist-in 3.272 C336S None None XRAY 1.998 0.175 0.221 B 364 325 0 0 0 0 [[40, 325]] 1.0 5ooi Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 6HMBA P19784 7 334 350.0 3NG:413 Type1 Inactive DFGin 7.526 16.135 BLAminus -111.55, 174.56 58.24, 78.46 -87.65, 16.17 297.85, 81.04 -69.02, -17.39 in-in in 9.184 Saltbr-in 2.771 HRD-in -73.83, -48.37 71.6, 10.44 in-in-out SNCiio in-out ActLoopNT-in 2.872 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -135.43, 166.43 APE9-dihe-na 65.52, 156.91 APE8-dihe-in -69.62, 146.48 APE8-rot-out 153.38 APE67-dihe-in -70.99, -14.32 -39.92, -51.06 APE12-dist-in 12.572 APE11-dist-in 10.14 APE10-dist-in 6.125 APE9-dist-in 3.269 C336S None None XRAY 1.04 0.135 0.146 A 364 328 0 0 0 0 [[40, 325]] 1.0 6hmb Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 6HMCA P19784 7 333 350.0 FXB:409 Type1 Inactive DFGin 7.484 15.944 BLAminus -113.63, 176.44 57.73, 79.28 -91.48, 17.74 297.31, 81.27 -70.68, -18.72 in-in in 9.16 Saltbr-in 2.731 HRD-in -73.83, -49.11 72.06, 11.42 in-in-out SNCiio in-out ActLoopNT-in 2.857 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -135.54, 169.71 APE9-dihe-na 63.32, 163.11 APE8-dihe-in -83.38, 144.56 APE8-rot-out 152.32 APE67-dihe-in -69.74, -13.64 -38.13, -54.44 APE12-dist-in 12.722 APE11-dist-in 10.359 APE10-dist-in 6.271 APE9-dist-in 3.135 C336S None None XRAY 1.03 0.123 0.136 A 364 327 0 0 0 0 [[40, 325]] 1.0 6hmc Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 6HMQA P19784 7 333 350.0 4B0:415 Type1 Inactive DFGin 7.516 15.897 BLAminus -111.51, 179.46 53.94, 78.75 -91.06, 16.94 297.02, 81.67 -70.65, -17.57 in-in in 9.287 Saltbr-in 2.7 HRD-in -71.74, -48.86 71.13, 9.58 in-in-out SNCiio in-out ActLoopNT-in 2.865 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.74, 167.44 APE9-dihe-na 67.55, 158.31 APE8-dihe-in -74.76, 147.19 APE8-rot-out 151.59 APE67-dihe-in -69.87, -15.26 -38.65, -53.1 APE12-dist-in 12.719 APE11-dist-in 10.372 APE10-dist-in 6.276 APE9-dist-in 3.216 C336S None None XRAY 0.97 0.12 0.132 A 364 327 0 0 0 0 [[40, 325]] 1.0 6hmq Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 6TE2A P19784 7 333 350.0 N4N:401 Type1 Inactive DFGin 7.421 16.061 BLAminus -111.05, 175.8 56.4, 79.66 -88.88, 16.84 297.11, 78.92 -68.29, -19.45 in-in in 9.179 Saltbr-in 2.737 HRD-in -72.08, -49.24 70.76, 10.56 in-in-out SNCiio in-out ActLoopNT-in 2.873 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -135.35, 169.57 APE9-dihe-na 64.14, 158.38 APE8-dihe-in -66.19, 145.41 APE8-rot-out 157.88 APE67-dihe-in -69.6, -15.07 -41.34, -52.47 APE12-dist-in 12.719 APE11-dist-in 10.288 APE10-dist-in 6.229 APE9-dist-in 3.183 C336S None None XRAY 0.922 0.128 0.146 A 364 327 0 0 0 0 [[40, 325]] 1.0 6te2 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 6TEWA P19784 8 332 350.0 N5Q:401 Type1 Inactive DFGin 7.448 16.034 BLAminus -113.38, 177.77 58.49, 75.16 -86.58, 13.21 300.09, 80.6 -71.98, -13.55 in-in in 9.191 Saltbr-in 2.764 HRD-in -73.42, -50.71 73.31, 9.16 in-in-out SNCiio in-out ActLoopNT-in 2.855 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -131.31, 166.05 APE9-dihe-na 67.84, 155.34 APE8-dihe-in -69.52, 145.77 APE8-rot-out 155.55 APE67-dihe-in -69.47, -12.71 -39.54, -51.77 APE12-dist-in 12.644 APE11-dist-in 10.283 APE10-dist-in 6.214 APE9-dist-in 3.257 C336S None None XRAY 1.082 0.146 0.169 A 364 325 0 0 0 0 [[40, 325]] 1.0 6tew Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 6TGUA P19784 7 333 350.0 N92:401 Type1 Inactive DFGin 7.552 16.026 BLAminus -112.26, 176.73 56.77, 81.01 -91.35, 17.51 296.45, 79.92 -71.68, -16.8 in-in in 9.305 Saltbr-in 2.722 HRD-in -72.82, -48.7 70.26, 12.12 in-in-out SNCiio in-out ActLoopNT-in 2.834 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.89, 165.93 APE9-dihe-na 69.32, 157.2 APE8-dihe-in -71.77, 145.51 APE8-rot-out 156.69 APE67-dihe-in -70.82, -14.46 -40.19, -51.48 APE12-dist-in 12.593 APE11-dist-in 10.174 APE10-dist-in 6.18 APE9-dist-in 3.226 C336S None None XRAY 0.833 0.144 0.167 A 364 327 0 0 0 0 [[40, 325]] 1.0 6tgu Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 7A1BA P19784 7 333 350.0 QXW:401 Type1 Inactive DFGin 7.327 15.884 BLAminus -115.07, -178.02 53.32, 79.29 -92.21, 18.25 295.46, 80.51 -70.04, -17.41 in-in in 9.068 Saltbr-in 2.755 HRD-in -73.66, -51.05 73.02, 12.19 in-in-out SNCiio in-out ActLoopNT-in 2.839 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -134.84, 165.88 APE9-dihe-na 65.99, 155.29 APE8-dihe-in -66.47, 144.14 APE8-rot-out 158.1 APE67-dihe-in -72.39, -14.92 -39.21, -49.13 APE12-dist-in 12.514 APE11-dist-in 10.155 APE10-dist-in 6.126 APE9-dist-in 3.214 C336S None None XRAY 1.287 0.158 0.193 A 364 327 0 0 0 0 [[40, 325]] 1.0 7a1b Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 7A1ZA P19784 7 334 350.0 QWN:401 Type1 Inactive DFGin 7.312 15.896 BLAminus -116.55, -179.0 52.86, 77.15 -87.42, 15.76 295.79, 82.41 -71.1, -20.14 in-in in 9.118 Saltbr-in 2.742 HRD-in -73.36, -49.56 72.51, 9.81 in-in-out SNCiio in-out ActLoopNT-in 2.863 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.57, 169.23 APE9-dihe-na 63.17, 159.93 APE8-dihe-in -69.83, 147.92 APE8-rot-out 159.64 APE67-dihe-in -69.01, -16.02 -43.66, -52.53 APE12-dist-in 12.616 APE11-dist-in 10.202 APE10-dist-in 6.207 APE9-dist-in 3.183 None None None XRAY 1.024 0.135 0.147 A 364 328 0 0 0 0 [[40, 325]] 1.0 7a1z Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 7A22A P19784 6 333 350.0 QWW:402 Type1 Inactive DFGin 7.492 16.044 BLAminus -109.78, 176.65 59.74, 75.57 -89.61, 15.1 296.52, 81.12 -70.26, -18.33 in-in in 9.319 Saltbr-in 2.717 HRD-in -73.24, -49.68 72.33, 11.09 in-in-out SNCiio in-out ActLoopNT-in 2.867 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.67, 168.35 APE9-dihe-na 65.98, 155.42 APE8-dihe-in -69.68, 147.26 APE8-rot-out 153.84 APE67-dihe-in -70.15, -15.96 -40.75, -51.45 APE12-dist-in 12.577 APE11-dist-in 10.137 APE10-dist-in 6.159 APE9-dist-in 3.273 None None None XRAY 1.01 0.138 0.166 A 364 328 0 0 0 0 [[40, 325]] 1.0 7a22 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 7A2HA P19784 7 331 350.0 QX2:401 Type1 Inactive DFGin 7.455 15.919 BLAminus -112.63, 178.67 55.25, 78.15 -89.38, 17.48 296.64, 81.25 -70.47, -18.74 in-in in 9.252 Saltbr-in 2.72 HRD-in -73.22, -50.01 71.53, 12.72 in-in-out SNCiio in-out ActLoopNT-in 2.884 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -135.32, 172.31 APE9-dihe-na 60.65, 166.53 APE8-dihe-in -82.84, 147.93 APE8-rot-out 156.9 APE67-dihe-in -69.19, -14.65 -40.46, -56.2 APE12-dist-in 12.648 APE11-dist-in 10.22 APE10-dist-in 6.217 APE9-dist-in 3.094 None None None XRAY 1.01 0.143 0.149 A 364 325 0 0 0 0 [[40, 325]] 1.0 7a2h Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 8Q9SA P19784 7 333 350.0 QBE:401 Type1 Inactive DFGin 7.562 16.186 BLAminus -112.11, 177.67 54.72, 78.76 -89.62, 18.88 296.03, 82.59 -69.97, -18.03 in-in in 9.052 Saltbr-in 2.854 HRD-in -74.44, -49.67 70.19, 11.37 in-in-out SNCiio in-out ActLoopNT-in 2.877 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.65, 169.16 APE9-dihe-na 66.75, 157.23 APE8-dihe-in -72.24, 148.68 APE8-rot-out 154.8 APE67-dihe-in -70.93, -15.32 -42.93, -49.67 APE12-dist-in 12.643 APE11-dist-in 10.326 APE10-dist-in 6.164 APE9-dist-in 3.273 C336S None None XRAY 1.352 0.137 0.169 A 364 327 0 0 0 0 [[40, 325]] 1.0 8q9s Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 8QCDA P19784 7 333 350.0 TBS:402 Type1 Inactive DFGin 7.384 16.126 BLAminus -114.5, 177.89 62.48, 71.57 -90.43, 15.0 296.22, 81.56 -72.45, -14.89 in-in in 9.456 Saltbr-in 2.787 HRD-in -74.09, -49.74 73.57, 10.6 in-in-out SNCiio in-out ActLoopNT-in 2.834 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -136.12, 167.72 APE9-dihe-na 66.59, 156.6 APE8-dihe-in -73.54, 148.52 APE8-rot-out 150.56 APE67-dihe-in -71.43, -15.51 -42.4, -50.04 APE12-dist-in 12.556 APE11-dist-in 10.11 APE10-dist-in 6.138 APE9-dist-in 3.237 C336S None None XRAY 1.03 0.144 0.156 A 364 327 0 0 0 0 [[40, 325]] 1.0 8qcd Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 8QF1A P19784 7 329 350.0 GNP:401 Type1 Inactive DFGin 7.466 16.288 BLAminus -114.86, -178.48 60.39, 75.92 -94.77, 22.65 297.03, 83.05 -72.96, -19.62 in-in in 9.607 Saltbr-in 2.954 HRD-in -74.34, -50.7 74.96, 8.25 in-in-out SNCiio in-out ActLoopNT-in 2.923 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.96, 167.78 APE9-dihe-na 70.02, 160.85 APE8-dihe-in -83.43, 149.5 APE8-rot-out 162.15 APE67-dihe-in -65.8, -15.89 -45.17, -53.3 APE12-dist-in 12.699 APE11-dist-in 10.346 APE10-dist-in 6.16 APE9-dist-in 3.192 C336S None None XRAY 1.32 0.214 0.232 A 364 323 0 0 0 0 [[40, 325]] 1.0 8qf1 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9FBIA P19784 7 333 350.0 NIO:401 Type1 Inactive DFGin 7.398 16.126 BLAminus -117.51, 178.09 54.8, 75.35 -88.6, 16.43 294.32, 81.79 -66.23, -19.3 in-in in 9.236 Saltbr-in 2.845 HRD-in -76.16, -47.39 73.52, 9.76 in-in-out SNCiio in-out ActLoopNT-in 2.892 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.37, 166.15 APE9-dihe-na 70.34, 154.33 APE8-dihe-in -71.36, 149.29 APE8-rot-out 153.93 APE67-dihe-in -72.01, -15.91 -47.59, -45.82 APE12-dist-in 12.469 APE11-dist-in 10.094 APE10-dist-in 6.031 APE9-dist-in 3.362 C336S None None XRAY 1.161 0.146 0.185 A 364 327 0 0 0 0 [[40, 325]] 1.0 9fbi Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9FBIB P19784 5 333 350.0 NIO:401 Type1 Inactive DFGin 7.471 16.3 BLAminus -116.61, 178.26 54.58, 80.03 -91.17, 14.79 296.76, 82.15 -70.7, -15.45 in-in in 9.643 Saltbr-in 2.697 HRD-in -74.94, -47.04 69.95, 13.58 in-in-out SNCiio in-out ActLoopNT-in 2.872 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -136.62, 165.93 APE9-dihe-na 67.12, 156.73 APE8-dihe-in -70.88, 146.98 APE8-rot-out 150.31 APE67-dihe-in -70.99, -16.75 -44.95, -47.09 APE12-dist-in 12.635 APE11-dist-in 10.43 APE10-dist-in 6.209 APE9-dist-in 3.336 C336S None None XRAY 1.161 0.146 0.185 B 364 329 0 0 0 0 [[40, 325]] 1.0 9fbi Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9GXYA P19784 7 333 350.0 A1IKB:401 Type1 Inactive DFGin 7.52 16.131 BLAminus -109.28, 174.99 57.45, 78.77 -89.21, 16.87 296.94, 82.45 -70.07, -17.54 in-in in 9.251 Saltbr-in 2.768 HRD-in -74.35, -49.25 74.22, 9.99 in-in-out SNCiio in-out ActLoopNT-in 2.857 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.85, 167.52 APE9-dihe-na 67.21, 153.72 APE8-dihe-in -71.12, 145.73 APE8-rot-out 156.37 APE67-dihe-in -72.51, -16.52 -40.49, -47.9 APE12-dist-in 12.608 APE11-dist-in 10.214 APE10-dist-in 6.195 APE9-dist-in 3.297 C336S None None XRAY 1.16 0.161 0.178 A 364 327 0 0 0 0 [[40, 325]] 1.0 9gxy Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9H96A P19784 7 333 350.0 A1ITG:402 Type1 Inactive DFGin 7.377 16.005 BLAminus -114.22, -178.12 57.34, 74.65 -89.54, 12.65 295.7, 85.87 -70.13, -16.33 in-in in 9.213 Saltbr-in 2.792 HRD-in -73.4, -48.91 72.8, 11.83 in-in-out SNCiio in-out ActLoopNT-in 2.838 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.4, 169.21 APE9-dihe-na 64.47, 158.05 APE8-dihe-in -82.79, 147.55 APE8-rot-out 81.98 APE67-dihe-in -74.05, -13.74 -38.35, -50.65 APE12-dist-in 12.553 APE11-dist-in 10.136 APE10-dist-in 6.175 APE9-dist-in 3.202 C336S None None XRAY 1.04 0.173 0.186 A 364 327 0 0 0 0 [[40, 325]] 1.0 9h96 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9R57A P19784 7 334 350.0 7M0:401 Type1 Inactive DFGin 7.314 15.807 BLAminus -117.79, 179.38 55.53, 79.18 -90.13, 13.15 296.08, 81.93 -68.23, -17.94 in-in in 9.094 Saltbr-in 2.752 HRD-in -73.03, -49.59 68.72, 13.27 in-in-out SNCiio in-out ActLoopNT-in 2.889 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.7, 168.76 APE9-dihe-na 64.02, 159.35 APE8-dihe-in -72.38, 147.39 APE8-rot-out 152.37 APE67-dihe-in -71.68, -13.05 -42.66, -49.27 APE12-dist-in 12.551 APE11-dist-in 10.15 APE10-dist-in 6.154 APE9-dist-in 3.205 C336S None None XRAY 1.1 0.131 0.15 A 364 328 0 0 0 0 [[40, 325]] 1.0 9r57 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9R5DA P19784 7 334 350.0 A1JC0:406 Type1 Inactive DFGin 7.397 15.991 BLAminus -112.64, 177.28 54.75, 80.13 -91.2, 16.14 298.04, 79.89 -68.67, -15.46 in-in in 9.155 Saltbr-in 2.785 HRD-in -70.54, -55.64 77.27, 10.9 in-in-out SNCiio in-out ActLoopNT-in 2.893 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.81, 166.64 APE9-dihe-na 65.63, 157.17 APE8-dihe-in -69.71, 147.08 APE8-rot-out 154.67 APE67-dihe-in -68.42, -16.02 -40.11, -53.54 APE12-dist-in 12.649 APE11-dist-in 10.201 APE10-dist-in 6.191 APE9-dist-in 3.338 C336S None None XRAY 1.02 0.172 0.193 A 364 328 0 0 0 0 [[40, 325]] 1.0 9r5d Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9R5FA P19784 6 334 350.0 A1JCX:401 Type1 Inactive DFGin 7.35 15.905 BLAminus -117.44, 178.99 56.69, 78.93 -92.83, 18.1 296.95, 81.34 -70.97, -17.8 in-in in 9.203 Saltbr-in 2.792 HRD-in -75.16, -48.41 71.64, 9.51 in-in-out SNCiio in-out ActLoopNT-in 2.855 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -135.8, 164.78 APE9-dihe-na 69.96, 156.03 APE8-dihe-in -69.35, 144.23 APE8-rot-out 157.94 APE67-dihe-in -69.64, -14.56 -36.99, -53.5 APE12-dist-in 12.569 APE11-dist-in 10.151 APE10-dist-in 6.146 APE9-dist-in 3.236 C336S None None XRAY 1.19 0.128 0.155 A 364 329 0 0 0 0 [[40, 325]] 1.0 9r5f Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 5M56A P19784 2 332 350.0 7FC:401 Type1 Inactive DFGin 7.484 16.163 BLAminus -120.51, -175.94 56.7, 79.26 -99.94, 22.01 296.38, 82.8 -72.58, -18.8 in-in in 9.424 Saltbr-in 2.815 HRD-in -72.47, -50.26 70.15, 13.52 in-in-out SNCiio in-out ActLoopNT-in 2.854 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -131.02, 171.03 APE9-dihe-na 64.0, 165.13 APE8-dihe-in -83.29, 148.42 APE8-rot-out 157.63 APE67-dihe-in -65.78, -16.01 -46.77, -49.28 APE12-dist-in 12.506 APE11-dist-in 10.259 APE10-dist-in 6.034 APE9-dist-in 3.241 D39G,C336S None None XRAY 2.237 0.165 0.206 A 364 331 0 0 0 0 [[40, 325]] 1.0 5m56 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9Q8QA P19784 7 333 350.0 A1I4N:401 Type1 Inactive DFGin 7.435 16.148 BLAminus -112.68, 177.57 58.61, 78.98 -92.73, 15.92 297.62, 79.91 -72.06, -16.96 in-in in 9.34 Saltbr-in 2.806 HRD-in -74.27, -50.0 73.78, 9.25 in-in-out SNCiio in-out ActLoopNT-in 2.85 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.21, 172.35 APE9-dihe-na 59.23, 162.09 APE8-dihe-in -80.22, 145.17 APE8-rot-out 152.48 APE67-dihe-in -71.89, -13.6 -38.8, -51.77 APE12-dist-in 12.709 APE11-dist-in 10.31 APE10-dist-in 6.23 APE9-dist-in 3.195 C336S None None XRAY 0.98 0.148 0.179 A 370 327 0 0 0 0 [[40, 325]] 1.0 9q8q Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9Q9CA P19784 7 334 350.0 R9D:401 Type1 Inactive DFGin 7.382 16.051 BLAminus -115.41, -178.92 55.54, 79.61 -92.68, 21.11 295.96, 82.33 -72.43, -17.63 in-in in 9.279 Saltbr-in 2.769 HRD-in -77.12, -49.51 73.81, 10.58 in-in-out SNCiio in-out ActLoopNT-in 2.923 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.05, 167.7 APE9-dihe-na 65.8, 158.52 APE8-dihe-in -75.93, 148.76 APE8-rot-out 142.61 APE67-dihe-in -68.36, -15.2 -41.25, -53.72 APE12-dist-in 12.706 APE11-dist-in 10.443 APE10-dist-in 6.22 APE9-dist-in 3.171 C336S None None XRAY 1.66 0.189 0.223 A 370 328 0 0 0 0 [[40, 325]] 1.0 9q9c Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9QAKA P19784 7 333 350.0 A1I5I:401 Type1 Inactive DFGin 7.409 16.124 BLAminus -112.6, 179.42 55.7, 76.11 -85.75, 16.58 297.35, 81.8 -69.57, -20.03 in-in in 9.206 Saltbr-in 2.746 HRD-in -73.81, -50.84 74.7, 9.74 in-in-out SNCiio in-out ActLoopNT-in 2.855 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -130.0, 170.78 APE9-dihe-na 62.74, 160.85 APE8-dihe-in -81.27, 148.15 APE8-rot-out 149.99 APE67-dihe-in -71.47, -12.75 -42.8, -50.68 APE12-dist-in 12.76 APE11-dist-in 10.41 APE10-dist-in 6.292 APE9-dist-in 3.214 C336S None None XRAY 0.98 0.148 0.175 A 370 327 0 0 0 0 [[40, 325]] 1.0 9qak Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9QB0A P19784 7 333 350.0 U8X:401 Type1 Inactive DFGin 7.345 16.011 BLAminus -113.24, -179.77 61.72, 72.14 -90.08, 15.6 294.29, 83.61 -71.01, -17.3 in-in in 9.195 Saltbr-in 2.76 HRD-in -73.69, -49.59 74.02, 8.45 in-in-out SNCiio in-out ActLoopNT-in 2.868 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -128.71, 171.25 APE9-dihe-na 61.16, 162.09 APE8-dihe-in -81.48, 146.71 APE8-rot-out 153.91 APE67-dihe-in -69.1, -14.07 -38.93, -54.07 APE12-dist-in 12.732 APE11-dist-in 10.348 APE10-dist-in 6.255 APE9-dist-in 3.22 C336S None None XRAY 1.01 0.14 0.156 A 370 327 0 0 0 0 [[40, 325]] 1.0 9qb0 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9HK5A P19784 7 334 350.0 3NG:402 Type1 Inactive DFGin 7.542 16.208 BLAminus -114.65, -179.29 53.64, 80.01 -92.35, 20.62 296.39, 82.42 -74.28, -17.08 in-in in 9.271 Saltbr-in 2.826 HRD-in -73.22, -49.09 72.9, 4.28 in-in-out SNCiio in-out ActLoopNT-in 2.899 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -134.78, 167.23 APE9-dihe-na 62.78, 157.39 APE8-dihe-in -75.16, 149.06 APE8-rot-out 147.29 APE67-dihe-in -68.84, -16.32 -43.13, -50.25 APE12-dist-in 12.694 APE11-dist-in 10.358 APE10-dist-in 6.315 APE9-dist-in 3.288 P32V,V83I,T101I,C336S None None XRAY 1.491 0.175 0.204 A 364 328 0 0 0 0 [[40, 325]] 1.0 9hk5 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 3.1e-70 242.7 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9Q9AA P19784 7 333 350.0 3NG:401,A1I4V:402 Type1,Allosteric Inactive DFGin 7.397 16.171 BLAminus -114.27, 179.87 56.61, 76.76 -86.69, 17.58 298.08, 81.74 -71.41, -19.01 in-in in 9.247 Saltbr-in 2.776 HRD-in -75.92, -48.72 71.51, 10.14 in-in-out SNCiio in-out ActLoopNT-in 2.902 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -131.5, 165.78 APE9-dihe-na 68.3, 154.64 APE8-dihe-in -67.27, 146.08 APE8-rot-out 156.93 APE67-dihe-in -69.44, -15.07 -43.26, -49.96 APE12-dist-in 12.724 APE11-dist-in 10.389 APE10-dist-in 6.234 APE9-dist-in 3.275 C336S None None XRAY 1.03 0.147 0.156 A 370 327 0 0 0 0 [[40, 325]] 1.0 9q9a Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9Q9DA P19784 7 332 350.0 3NG:401,R9G:402 Type1,Allosteric Inactive DFGin 7.413 16.113 BLAminus -111.11, 176.5 58.97, 76.86 -90.38, 17.87 296.15, 81.91 -69.6, -18.64 in-in in 9.215 Saltbr-in 2.79 HRD-in -72.74, -49.53 71.25, 10.86 in-in-out SNCiio in-out ActLoopNT-in 2.9 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -129.74, 169.32 APE9-dihe-na 66.15, 161.19 APE8-dihe-in -81.94, 147.26 APE8-rot-out 152.61 APE67-dihe-in -69.62, -15.68 -40.15, -53.5 APE12-dist-in 12.735 APE11-dist-in 10.379 APE10-dist-in 6.221 APE9-dist-in 3.183 C336S None None XRAY 0.89 0.148 0.159 A 370 326 0 0 0 0 [[40, 325]] 1.0 9q9d Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9QAGA P19784 7 333 350.0 3NG:401,RBJ:402 Type1,Allosteric Inactive DFGin 7.402 16.146 BLAminus -113.78, 178.8 55.06, 77.97 -89.73, 16.81 296.32, 81.5 -70.74, -16.11 in-in in 9.239 Saltbr-in 2.765 HRD-in -72.83, -48.69 70.11, 10.59 in-in-out SNCiio in-out ActLoopNT-in 2.868 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.87, 167.19 APE9-dihe-na 64.82, 157.5 APE8-dihe-in -76.42, 146.88 APE8-rot-out 148.1 APE67-dihe-in -71.68, -14.1 -39.59, -52.28 APE12-dist-in 12.68 APE11-dist-in 10.313 APE10-dist-in 6.249 APE9-dist-in 3.264 C336S None None XRAY 1.01 0.136 0.162 A 370 327 0 0 0 0 [[40, 325]] 1.0 9qag Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9Q8CA P19784 7 333 350.0 T9Y:401,T9Y:402,T9Y:403 Type1,Allosteric,Allosteric Inactive DFGin 7.412 16.128 BLAminus -115.35, 178.24 56.83, 76.39 -88.66, 16.23 297.18, 81.04 -70.16, -17.0 in-in in 9.249 Saltbr-in 2.784 HRD-in -74.57, -48.4 71.88, 8.6 in-in-out SNCiio in-out ActLoopNT-in 2.857 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.09, 170.22 APE9-dihe-na 64.38, 165.03 APE8-dihe-in -88.54, 146.5 APE8-rot-out 149.16 APE67-dihe-in -69.16, -17.37 -38.39, -54.09 APE12-dist-in 12.734 APE11-dist-in 10.334 APE10-dist-in 6.247 APE9-dist-in 3.119 C336S None None XRAY 0.9 0.135 0.148 A 370 327 0 0 0 0 [[40, 325]] 1.0 9q8c Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 9Q9GA P19784 7 333 350.0 R9J:401,R9J:402,R9J:403 Type1,Allosteric,Allosteric Inactive DFGin 7.41 16.176 BLAminus -116.31, 174.81 56.6, 81.53 -91.38, 17.7 296.35, 80.59 -69.73, -20.26 in-in in 9.271 Saltbr-in 2.724 HRD-in -73.54, -50.11 73.56, 10.08 in-in-out SNCiio in-out ActLoopNT-in 2.864 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.48, 171.2 APE9-dihe-na 62.47, 166.71 APE8-dihe-in -88.41, 146.96 APE8-rot-out 149.88 APE67-dihe-in -69.36, -14.73 -39.72, -53.83 APE12-dist-in 12.781 APE11-dist-in 10.412 APE10-dist-in 6.302 APE9-dist-in 3.157 C336S None None XRAY 0.94 0.139 0.157 A 370 327 0 0 0 0 [[40, 325]] 1.0 9q9g Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CSK22_HUMAN 3E3BX P19784 1 334 350.0 CCK:351 Type1 Inactive DFGin 7.932 16.543 None -60.71, 173.45 58.68, 153.51 -167.77, 24.29 292.11, 94.72 -71.5, -16.51 in-in in 9.967 Saltbr-in 3.176 HRD-in -22.7, -49.66 82.48, 4.05 in-in-in SNCiii in-in ActLoopNT-in 3.536 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -113.37, 167.02 APE9-dihe-na 87.1, -164.84 APE8-dihe-in -118.3, 158.91 APE8-rot-in 284.14 APE67-dihe-in -147.62, -14.08 -66.97, 28.66 APE12-dist-in 13.039 APE11-dist-in 10.823 APE10-dist-in 6.236 APE9-dist-in 3.647 None None None XRAY 3.2 0.268 0.274 X 339 334 0 0 0 0 [[40, 325]] 1.0 3e3b Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'

CMGC_CSNK2A2 (Casein kinase II subunit alpha')

Total number of chains: 0
Active chains: 0
Family: CMGC
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

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SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name