CAMK_CHEK1 (Serine/threonine-protein kinase Chk1)

Total number of chains: 171
Active chains: 160
Family: CAMK
Uniprot: CHK1_HUMAN
Kinase Domain Residues: 9 - 265
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 171 100.0% AF-O14757-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

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PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
7AKMA 2 271 476.0 AGS:401 ATPlike Active DFGin 6.775 14.143 BLAminus -128.66, 150.55 71.15, 96.3 -103.32, 28.49 292.74, 82.8 -70.74, -21.81 in-in in 9.111 Saltbr-in 2.706 HRD-in -78.28, -45.32 76.75, -0.14 in-in-in SNCiii in-in ActLoopNT-in 3.011 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -163.43, 171.3 APE9-dihe-na 110.38, -147.97 APE8-dihe-in -135.73, 125.59 APE8-rot-in 300.71 APE67-dihe-in -62.97, -17.75 -56.42, -42.48 APE12-dist-in 9.309 APE11-dist-in 11.674 APE10-dist-in 6.171 APE9-dist-in 3.407 D10R None None XRAY 1.93 0.199 0.242 A 298 270 0 0 0 0 [[9, 265]] 1.0 7akm CAMK_CHEK1_HUMAN CAMK 3.4e-71 245.5 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
3JVRA 2 272 476.0 AGX:901 Allosteric Active DFGin 6.872 14.177 BLAminus -127.98, 150.64 73.31, 94.81 -103.55, 30.03 289.43, 82.54 -69.18, -19.03 in-in in 8.831 Saltbr-in 2.689 HRD-in -74.95, -44.7 78.13, -0.66 in-in-in SNCiii in-in ActLoopNT-in 2.948 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.38, 173.26 APE9-dihe-na 116.8, -150.87 APE8-dihe-in -139.69, 123.15 APE8-rot-in 300.09 APE67-dihe-in -61.84, -23.11 -49.41, -48.15 APE12-dist-in 8.931 APE11-dist-in 11.813 APE10-dist-in 6.298 APE9-dist-in 3.406 None None None XRAY 1.76 0.202 0.225 A 271 258 13 0 0 0 [[9, 265]] 1.0 3jvr CAMK_CHEK1_HUMAN CAMK 2e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
3F9NA 7 270 476.0 38M:324 Allosteric Active DFGin 6.871 14.306 BLAminus -120.26, 153.9 73.21, 93.52 -100.46, 25.66 293.37, 83.17 -66.45, -28.23 in-in in 8.857 Saltbr-in 2.555 HRD-in -79.56, -43.26 73.24, -2.23 in-in-in SNCiii in-in ActLoopNT-in 3.014 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.39, 152.53 APE9-dihe-na 120.62, -163.45 APE8-dihe-in -134.2, 121.67 APE8-rot-in 301.99 APE67-dihe-in -60.59, -25.68 -41.41, -51.19 APE12-dist-in 9.146 APE11-dist-in 11.147 APE10-dist-in 5.801 APE9-dist-in 3.398 None None None XRAY 1.9 0.184 0.216 A 322 253 11 0 0 0 [[9, 265]] 1.0 3f9n CAMK_CHEK1_HUMAN CAMK 3.8e-71 245.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
AF-O14757-K1A 1 273 476.0 No_ligand No_ligand Active DFGin 6.908 13.879 BLAminus -126.41, 173.77 59.88, 75.65 -83.37, 18.3 292.07, 88.25 -61.72, -28.43 in-in in 8.997 Saltbr-in 2.756 HRD-in -81.68, -47.56 71.58, -4.39 in-in-in SNCiii in-in ActLoopNT-in 3.002 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -162.33, 169.83 APE9-dihe-na 111.71, 175.87 APE8-dihe-in -92.2, 123.21 APE8-rot-in 308.56 APE67-dihe-in -63.62, -24.82 -49.79, -44.17 APE12-dist-in 9.178 APE11-dist-in 11.671 APE10-dist-in 6.144 APE9-dist-in 3.634 None None None AF2 -1.0 1.0 1.0 A 273 273 0 0 0 0 [[9, 265]] 1.0 AF-O14757-K1 CAMK_CHEK1_HUMAN CAMK 2.1e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
AF-O14757-K3A 1 273 476.0 No_ligand No_ligand Active DFGin 6.65 13.867 BLAminus -123.65, -177.83 47.33, 73.45 -76.38, 14.64 294.74, 95.75 -58.94, -31.14 in-in in 8.964 Saltbr-in 2.728 HRD-in -82.53, -48.74 68.72, 4.29 in-in-in SNCiii in-in ActLoopNT-in 2.933 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.6, 168.78 APE9-dihe-na 104.0, 175.5 APE8-dihe-in -88.64, 126.31 APE8-rot-in 306.94 APE67-dihe-in -61.16, -29.27 -52.3, -41.96 APE12-dist-in 9.368 APE11-dist-in 11.541 APE10-dist-in 5.913 APE9-dist-in 3.334 None None None AF2 -1.0 1.0 1.0 A 273 273 0 0 0 0 [[9, 265]] 1.0 AF-O14757-K3 CAMK_CHEK1_HUMAN CAMK 2.1e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
1IA8A 2 276 476.0 No_ligand No_ligand Active DFGin 6.901 14.276 BLAminus -124.2, 154.39 68.94, 96.97 -102.1, 26.7 291.65, 79.3 -65.06, -22.41 in-in in 8.89 Saltbr-in 2.735 HRD-in -75.22, -41.37 69.04, 2.45 in-in-in SNCiii in-in ActLoopNT-in 2.925 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.12, 169.49 APE9-dihe-na 119.83, -148.37 APE8-dihe-in -135.5, 118.95 APE8-rot-in 302.64 APE67-dihe-in -61.39, -22.34 -35.34, -54.92 APE12-dist-in 8.917 APE11-dist-in 11.909 APE10-dist-in 6.335 APE9-dist-in 3.331 None None None XRAY 1.7 0.216 0.235 A 289 272 3 0 0 0 [[9, 265]] 1.0 1ia8 CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7AKMB 2 269 476.0 No_ligand No_ligand Active DFGin 6.729 14.236 BLAminus -131.2, 148.86 72.72, 94.14 -102.13, 30.13 293.9, 82.86 -70.24, -23.15 in-in in 8.062 Saltbr-in 2.923 HRD-in -73.93, -45.68 78.44, -0.49 in-in-in SNCiii in-in ActLoopNT-in 3.083 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.14, 171.41 APE9-dihe-na 115.69, -149.76 APE8-dihe-in -139.3, 121.55 APE8-rot-in 304.35 APE67-dihe-in -60.59, -21.72 -51.07, -46.17 APE12-dist-in 9.473 APE11-dist-in 11.679 APE10-dist-in 6.174 APE9-dist-in 3.588 D10R None None XRAY 1.93 0.199 0.242 B 298 268 0 0 0 0 [[9, 265]] 1.0 7akm CAMK_CHEK1_HUMAN CAMK 3.4e-71 245.5 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
1ZYSA 3 273 476.0 199:400 Type1 Active DFGin 6.822 14.043 BLAminus -125.46, 168.25 66.65, 88.29 -97.37, 27.49 292.37, 83.58 -68.83, -18.69 in-in in 9.041 Saltbr-in 2.559 HRD-in -84.01, -42.62 72.63, -1.0 in-in-in SNCiii in-in ActLoopNT-in 2.94 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.0, 171.72 APE9-dihe-na 116.11, -147.59 APE8-dihe-in -140.51, 125.84 APE8-rot-in 300.55 APE67-dihe-in -63.09, -21.21 -45.55, -50.46 APE12-dist-in 8.807 APE11-dist-in 12.021 APE10-dist-in 6.423 APE9-dist-in 3.289 None None None XRAY 1.7 0.227 0.26 A 273 271 0 0 0 0 [[9, 265]] 1.0 1zys CAMK_CHEK1_HUMAN CAMK 4.8e-71 245.0 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2E9VA 2 269 476.0 85A:1001 Type1 Active DFGin 6.975 14.637 BLAminus -131.54, 177.83 55.26, 98.09 -109.61, 30.41 286.66, 68.67 -62.59, -29.32 in-in in 8.701 Saltbr-in 2.67 HRD-in -76.45, -37.92 59.71, 14.92 in-in-in SNCiii in-in ActLoopNT-in 2.889 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.78, 168.23 APE9-dihe-na 122.1, -169.86 APE8-dihe-in -111.29, 110.84 APE8-rot-in 305.57 APE67-dihe-in -47.02, -35.65 -25.69, -68.51 APE12-dist-in 9.434 APE11-dist-in 11.908 APE10-dist-in 6.143 APE9-dist-in 3.595 None None None XRAY 2.0 0.279 0.333 A 268 268 0 0 0 0 [[9, 265]] 1.0 2e9v CAMK_CHEK1_HUMAN CAMK 2e-71 246.3 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2E9VB 2 269 476.0 85A:2001 Type1 Active DFGin 6.918 14.189 BLAminus -126.14, 170.02 63.09, 96.2 -109.54, 31.48 299.02, 75.08 -66.55, -19.9 in-in in 8.259 Saltbr-in 2.694 HRD-in -68.57, -49.41 72.45, 8.8 in-in-in SNCiii in-in ActLoopNT-in 3.096 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.77, 165.61 APE9-dihe-na 116.5, -156.5 APE8-dihe-in -122.27, 105.18 APE8-rot-in 303.15 APE67-dihe-in -59.07, -28.34 -21.14, -51.59 APE12-dist-in 9.033 APE11-dist-in 11.859 APE10-dist-in 6.153 APE9-dist-in 3.462 None None None XRAY 2.0 0.279 0.333 B 268 268 0 0 0 0 [[9, 265]] 1.0 2e9v CAMK_CHEK1_HUMAN CAMK 2e-71 246.3 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2E9OA 2 270 476.0 A58:1001 Type1 Active DFGin 6.931 14.179 BLAminus -128.32, 168.44 64.14, 94.25 -103.44, 34.01 291.92, 79.18 -71.63, -19.2 in-in in 8.896 Saltbr-in 2.777 HRD-in -74.31, -47.15 72.74, 4.43 in-in-in SNCiii in-in ActLoopNT-in 2.982 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -150.26, 171.72 APE9-dihe-na 111.42, -153.4 APE8-dihe-in -133.8, 111.32 APE8-rot-in 302.29 APE67-dihe-in -62.45, -26.48 -26.55, -51.1 APE12-dist-in 9.089 APE11-dist-in 11.704 APE10-dist-in 6.009 APE9-dist-in 3.225 None None None XRAY 2.1 0.229 0.259 A 269 269 0 0 0 0 [[9, 265]] 1.0 2e9o CAMK_CHEK1_HUMAN CAMK 2e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2E9PA 2 270 476.0 77A:1001 Type1 Active DFGin 7.029 14.727 BLAminus -133.16, 178.72 63.58, 82.88 -105.74, 27.5 294.08, 87.1 -69.81, -10.86 in-in in 8.751 Saltbr-in 3.178 HRD-in -78.51, -52.51 75.63, -2.35 in-in-in SNCiii in-in ActLoopNT-in 2.983 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.13, 159.0 APE9-dihe-na 119.96, -161.72 APE8-dihe-in -125.67, 103.78 APE8-rot-in 300.79 APE67-dihe-in -64.0, -31.79 -16.61, -54.34 APE12-dist-in 9.52 APE11-dist-in 11.427 APE10-dist-in 5.651 APE9-dist-in 3.067 None None None XRAY 2.6 0.237 0.296 A 269 269 0 0 0 0 [[9, 265]] 1.0 2e9p CAMK_CHEK1_HUMAN CAMK 2e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2E9UA 2 270 476.0 A25:1001 Type1 Active DFGin 7.011 14.113 BLAminus -132.04, 172.65 62.85, 89.38 -101.09, 30.5 293.08, 81.27 -73.07, -16.47 in-in in 8.634 Saltbr-in 2.594 HRD-in -70.01, -43.61 71.24, 2.07 in-in-in SNCiii in-in ActLoopNT-in 3.004 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.27, 170.1 APE9-dihe-na 118.87, -157.35 APE8-dihe-in -129.87, 116.69 APE8-rot-in 299.78 APE67-dihe-in -60.89, -25.73 -32.98, -51.09 APE12-dist-in 9.224 APE11-dist-in 11.666 APE10-dist-in 5.958 APE9-dist-in 3.289 None None None XRAY 2.0 0.242 0.277 A 269 269 0 0 0 0 [[9, 265]] 1.0 2e9u CAMK_CHEK1_HUMAN CAMK 2e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2GHGA 2 270 476.0 A53:1 Type1 Active DFGin 6.886 14.53 BLAminus -166.32, 170.51 70.16, 71.94 -87.0, 41.41 289.83, 76.15 -75.14, -46.9 in-in in 8.977 Saltbr-in 3.136 HRD-in -93.04, -17.87 49.7, 7.2 in-in-in SNCiii in-in ActLoopNT-in 3.17 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -119.48, 116.46 APE9-dihe-na -170.15, -133.06 APE8-dihe-in -140.13, 110.94 APE8-rot-in 291.04 APE67-dihe-in -68.96, -50.13 -35.06, -49.54 APE12-dist-in 8.896 APE11-dist-in 11.861 APE10-dist-in 6.332 APE9-dist-in 3.697 None None None XRAY 3.5 0.24 0.314 A 269 269 0 0 0 0 [[9, 265]] 1.0 2ghg CAMK_CHEK1_HUMAN CAMK 2e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2YWPA 2 270 476.0 A42:1 Type1 Active DFGin 6.846 14.194 BLAminus -128.34, 170.16 65.69, 87.88 -101.03, 37.84 293.97, 84.7 -68.74, -18.33 in-in in 8.773 Saltbr-in 2.586 HRD-in -63.32, -40.53 66.09, 3.77 in-in-in SNCiii in-in ActLoopNT-in 2.993 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.27, 147.17 APE9-dihe-na 141.47, -143.91 APE8-dihe-in -127.52, 116.49 APE8-rot-in 286.38 APE67-dihe-in -56.51, -33.62 -29.01, -64.65 APE12-dist-in 9.177 APE11-dist-in 11.697 APE10-dist-in 6.129 APE9-dist-in 3.396 None None None XRAY 2.9 0.242 0.297 A 269 269 0 0 0 0 [[9, 265]] 1.0 2ywp CAMK_CHEK1_HUMAN CAMK 2e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
3OT3A 4 272 476.0 22K:1 Type1 Active DFGin 7.072 14.088 BLAminus -119.38, 162.39 68.19, 101.86 -107.35, 22.12 289.5, 79.69 -65.92, -24.4 in-in in 8.404 Saltbr-in 2.644 HRD-in -72.88, -42.96 74.77, -4.22 in-in-in SNCiii in-in ActLoopNT-in 2.989 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -170.04, 168.72 APE9-dihe-na 114.72, -154.18 APE8-dihe-in -135.81, 120.72 APE8-rot-in 300.78 APE67-dihe-in -62.65, -21.04 -40.11, -52.91 APE12-dist-in 9.089 APE11-dist-in 11.425 APE10-dist-in 6.232 APE9-dist-in 3.377 None None None XRAY 1.44 0.185 0.202 A 273 261 8 0 0 0 [[9, 265]] 1.0 3ot3 CAMK_CHEK1_HUMAN CAMK 2.1e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
3OT8A 4 272 476.0 MI5:1 Type1 Active DFGin 7.0 14.027 BLAminus -120.24, 163.62 66.2, 100.88 -107.87, 26.52 289.17, 80.05 -67.79, -28.22 in-in in 8.382 Saltbr-in 2.676 HRD-in -76.11, -44.26 74.22, -4.28 in-in-in SNCiii in-in ActLoopNT-in 2.949 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.29, 156.87 APE9-dihe-na 115.01, -158.59 APE8-dihe-in -135.82, 120.71 APE8-rot-in 300.89 APE67-dihe-in -59.91, -23.22 -36.95, -56.24 APE12-dist-in 9.322 APE11-dist-in 11.252 APE10-dist-in 5.879 APE9-dist-in 3.304 None None None XRAY 1.645 0.179 0.202 A 273 255 14 0 0 0 [[9, 265]] 1.0 3ot8 CAMK_CHEK1_HUMAN CAMK 2.1e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
3PA3A 4 272 476.0 C70:1 Type1 Active DFGin 6.973 14.368 BLAminus -134.57, 168.81 69.42, 75.54 -91.88, 20.16 289.95, 77.58 -62.79, -19.4 in-in in 9.078 Saltbr-in 2.824 HRD-in -73.66, -45.33 74.44, -1.43 in-in-in SNCiii in-in ActLoopNT-in 2.937 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.61, 167.51 APE9-dihe-na 121.86, -151.66 APE8-dihe-in -134.95, 118.7 APE8-rot-in 302.9 APE67-dihe-in -63.51, -20.47 -39.03, -52.39 APE12-dist-in 8.919 APE11-dist-in 11.74 APE10-dist-in 6.138 APE9-dist-in 3.414 None None None XRAY 1.4 0.193 0.213 A 273 261 8 0 0 0 [[9, 265]] 1.0 3pa3 CAMK_CHEK1_HUMAN CAMK 2.1e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
3PA4A 6 272 476.0 C72:1 Type1 Active DFGin 6.965 14.377 BLAminus -132.17, 169.17 65.58, 76.35 -92.09, 21.91 286.75, 76.98 -63.13, -19.98 in-in in 9.009 Saltbr-in 2.792 HRD-in -74.13, -43.12 73.54, -3.04 in-in-in SNCiii in-in ActLoopNT-in 2.952 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.98, 170.48 APE9-dihe-na 119.01, -149.2 APE8-dihe-in -135.82, 117.84 APE8-rot-in 301.84 APE67-dihe-in -60.82, -20.24 -35.81, -56.24 APE12-dist-in 8.993 APE11-dist-in 11.732 APE10-dist-in 6.131 APE9-dist-in 3.403 None None None XRAY 1.59 0.225 0.25 A 273 259 8 0 0 0 [[9, 265]] 1.0 3pa4 CAMK_CHEK1_HUMAN CAMK 2.1e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
3PA5A 3 272 476.0 C73:1 Type1 Active DFGin 6.9 14.148 BLAminus -129.79, 167.68 66.08, 79.04 -93.62, 22.86 289.4, 76.66 -63.59, -21.02 in-in in 8.741 Saltbr-in 2.81 HRD-in -72.95, -46.5 75.39, -2.75 in-in-in SNCiii in-in ActLoopNT-in 2.904 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.77, 168.26 APE9-dihe-na 121.59, -150.46 APE8-dihe-in -134.42, 118.81 APE8-rot-in 303.4 APE67-dihe-in -64.55, -17.29 -34.12, -56.19 APE12-dist-in 9.139 APE11-dist-in 11.726 APE10-dist-in 6.199 APE9-dist-in 3.403 None None None XRAY 1.7 0.185 0.204 A 273 257 13 0 0 0 [[9, 265]] 1.0 3pa5 CAMK_CHEK1_HUMAN CAMK 2.1e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
3U9NA 7 272 476.0 09H:301 Type1 Active DFGin 6.902 14.222 BLAminus -129.35, 168.34 66.97, 89.35 -103.09, 30.47 290.62, 76.37 -69.94, -19.85 in-in in 8.941 Saltbr-in 2.98 HRD-in -75.25, -47.19 74.3, 0.38 in-in-in SNCiii in-in ActLoopNT-in 2.967 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.97, 166.31 APE9-dihe-na 118.13, -152.42 APE8-dihe-in -130.48, 118.2 APE8-rot-in 302.9 APE67-dihe-in -59.94, -25.46 -32.53, -57.85 APE12-dist-in 8.944 APE11-dist-in 11.526 APE10-dist-in 6.123 APE9-dist-in 3.378 None None None XRAY 1.85 0.197 0.229 A 273 258 8 0 0 0 [[9, 265]] 1.0 3u9n CAMK_CHEK1_HUMAN CAMK 2.1e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4JIKA 4 272 476.0 1KO:301 Type1 Active DFGin 6.844 14.415 BLAminus -132.96, 171.39 63.69, 79.56 -94.29, 22.22 287.36, 75.0 -62.33, -21.36 in-in in 9.309 Saltbr-in 3.102 HRD-in -69.23, -49.52 74.37, -4.01 in-in-in SNCiii in-in ActLoopNT-in 2.93 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.1, 158.36 APE9-dihe-na 125.39, -154.3 APE8-dihe-in -132.51, 118.9 APE8-rot-in 299.47 APE67-dihe-in -59.75, -20.56 -32.5, -57.47 APE12-dist-in 9.737 APE11-dist-in 11.499 APE10-dist-in 5.654 APE9-dist-in 3.284 None None None XRAY 1.9 0.211 0.237 A 273 256 13 0 0 0 [[9, 265]] 1.0 4jik CAMK_CHEK1_HUMAN CAMK 2.1e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2X8EA 9 270 476.0 X8E:1271 Type1 Active DFGin 6.973 14.28 BLAminus -124.04, 146.44 71.63, 110.62 -118.45, 20.59 294.1, 101.48 -77.34, -5.52 in-in in 8.746 Saltbr-in 2.746 HRD-in -57.57, -35.91 68.86, -17.53 in-in-in SNCiii in-in ActLoopNT-in 3.18 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.78, 160.7 APE9-dihe-na 116.57, -159.67 APE8-dihe-in -130.77, 130.86 APE8-rot-in 326.48 APE67-dihe-in -78.63, -14.78 -51.23, -40.57 APE12-dist-in 9.614 APE11-dist-in 11.717 APE10-dist-in 5.962 APE9-dist-in 3.777 None None None XRAY 2.5 0.235 0.309 A 276 259 3 0 0 0 [[9, 265]] 1.0 2x8e CAMK_CHEK1_HUMAN CAMK 2.2e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2YDJA 8 269 476.0 YDJ:1270 Type1 Active DFGin 6.852 14.043 BLAminus -131.16, 158.84 66.63, 79.17 -91.38, 22.19 287.3, 85.3 -65.89, -18.2 in-in in 8.595 Saltbr-in 3.078 HRD-in -81.14, -43.61 73.59, 1.69 in-in-in SNCiii in-in ActLoopNT-in 2.962 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.06, 143.33 APE9-dihe-na 116.46, -165.7 APE8-dihe-in -122.14, 128.4 APE8-rot-in 305.87 APE67-dihe-in -59.89, -24.88 -48.54, -44.68 APE12-dist-in 8.904 APE11-dist-in 11.531 APE10-dist-in 5.992 APE9-dist-in 3.703 None None CSS57,CSS168 XRAY 1.85 0.231 0.274 A 276 254 8 0 0 0 [[9, 265]] 1.0 2ydj CAMK_CHEK1_HUMAN CAMK 2.2e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2YDJB 9 269 476.0 YDJ:1270 Type1 Active DFGin 6.856 13.953 BLAminus -128.99, 157.39 65.68, 84.37 -94.19, 20.4 292.81, 85.67 -57.98, -21.82 in-in in 8.577 Saltbr-in 2.727 HRD-in -82.83, -45.03 78.79, -0.66 in-in-in SNCiii in-in ActLoopNT-in 2.925 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.08, 148.59 APE9-dihe-na 113.79, -160.81 APE8-dihe-in -130.66, 123.13 APE8-rot-in 312.19 APE67-dihe-in -61.27, -23.44 -46.66, -47.69 APE12-dist-in 8.761 APE11-dist-in 11.504 APE10-dist-in 5.881 APE9-dist-in 3.486 None None CSS57,CSS168 XRAY 1.85 0.231 0.274 B 276 253 8 0 0 0 [[9, 265]] 1.0 2ydj CAMK_CHEK1_HUMAN CAMK 2.2e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2YDKA 3 270 476.0 YDK:1277 Type1 Active DFGin 6.815 13.863 BLAminus -134.73, 157.08 71.98, 82.41 -98.21, 25.23 288.97, 82.35 -65.36, -21.41 in-in in 8.597 Saltbr-in 2.426 HRD-in -84.22, -45.96 71.26, 3.83 in-in-in SNCiii in-in ActLoopNT-in 2.985 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -80.97, 147.05 APE9-dihe-na 136.33, 158.87 APE8-dihe-in -85.44, 119.21 APE8-rot-in 306.85 APE67-dihe-in -66.77, -13.0 -53.89, -41.91 APE12-dist-in 8.362 APE11-dist-in 11.699 APE10-dist-in 5.907 APE9-dist-in 3.635 None None None XRAY 1.9 0.183 0.226 A 276 263 5 0 0 0 [[9, 265]] 1.0 2ydk CAMK_CHEK1_HUMAN CAMK 2.2e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2YERA 2 269 476.0 TQ1:1270 Type1 Active DFGin 6.756 14.258 BLAminus -124.59, 145.71 75.35, 98.7 -104.18, 25.73 293.91, 82.78 -62.89, -29.92 in-in in 8.96 Saltbr-in 2.625 HRD-in -76.13, -45.9 72.42, 1.41 in-in-in SNCiii in-in ActLoopNT-in 2.96 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.32, 169.84 APE9-dihe-na 113.06, -165.98 APE8-dihe-in -114.1, 119.87 APE8-rot-in 298.55 APE67-dihe-in -61.8, -19.78 -47.68, -48.11 APE12-dist-in 8.584 APE11-dist-in 11.797 APE10-dist-in 6.106 APE9-dist-in 3.296 None None None XRAY 1.83 0.147 0.175 A 276 268 0 0 0 0 [[9, 265]] 1.0 2yer CAMK_CHEK1_HUMAN CAMK 2.2e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2YEXA 2 270 476.0 YEX:1278 Type1 Active DFGin 6.893 14.384 BLAminus -127.36, 145.61 77.89, 95.73 -100.45, 22.36 290.83, 83.74 -60.39, -34.45 in-in in 8.981 Saltbr-in 2.687 HRD-in -75.84, -47.88 76.45, 1.35 in-in-in SNCiii in-in ActLoopNT-in 2.988 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.42, 168.54 APE9-dihe-na 112.0, -176.49 APE8-dihe-in -102.85, 121.8 APE8-rot-in 300.84 APE67-dihe-in -62.59, -19.14 -49.95, -47.33 APE12-dist-in 8.615 APE11-dist-in 11.848 APE10-dist-in 6.118 APE9-dist-in 3.454 None None None XRAY 1.3 0.135 0.164 A 276 269 0 0 0 0 [[9, 265]] 1.0 2yex CAMK_CHEK1_HUMAN CAMK 2.2e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
6FC8A 2 270 476.0 D4Q:302 Type1 Active DFGin 6.976 14.302 BLAminus -130.25, 169.7 63.03, 80.83 -96.98, 23.05 287.14, 83.19 -63.88, -21.11 in-in in 9.12 Saltbr-in 2.842 HRD-in -75.73, -49.32 70.88, 5.08 in-in-in SNCiii in-in ActLoopNT-in 2.936 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -147.0, 168.69 APE9-dihe-na 112.45, -173.34 APE8-dihe-in -100.21, 119.57 APE8-rot-in 309.11 APE67-dihe-in -65.13, -15.07 -45.17, -47.91 APE12-dist-in 8.643 APE11-dist-in 11.84 APE10-dist-in 6.238 APE9-dist-in 3.433 None None None XRAY 1.61 0.192 0.225 A 276 269 0 0 0 0 [[9, 265]] 1.0 6fc8 CAMK_CHEK1_HUMAN CAMK 2.2e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
6FCFA 9 269 476.0 D58:301 Type1 Active DFGin 7.066 14.096 BLAminus -128.16, 162.61 60.99, 87.16 -94.65, 19.56 290.65, 86.02 -63.74, -20.3 in-in in 8.493 Saltbr-in 2.851 HRD-in -74.13, -49.85 68.69, 7.55 in-in-in SNCiii in-in ActLoopNT-in 3.065 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -95.51, 152.5 APE9-dihe-na 100.58, 175.91 APE8-dihe-in -99.71, 122.4 APE8-rot-in 297.25 APE67-dihe-in -56.22, -27.58 -36.37, -48.59 APE12-dist-in 8.393 APE11-dist-in 11.389 APE10-dist-in 5.789 APE9-dist-in 3.943 None None CSS57,CSS168 XRAY 1.85 0.201 0.232 A 276 253 8 0 0 0 [[9, 265]] 1.0 6fcf CAMK_CHEK1_HUMAN CAMK 2.2e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
6FCKA 2 270 476.0 D4Z:301 Type1 Active DFGin 6.989 14.222 BLAminus -131.37, 171.79 60.5, 78.9 -94.42, 22.66 289.52, 83.51 -64.94, -20.94 in-in in 8.925 Saltbr-in 3.326 HRD-in -77.28, -47.72 71.32, 0.45 in-in-in SNCiii in-in ActLoopNT-in 3.0 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -112.05, 149.81 APE9-dihe-na 92.5, -170.86 APE8-dihe-in -92.88, 112.61 APE8-rot-in 313.22 APE67-dihe-in -64.0, -14.21 -41.55, -47.7 APE12-dist-in 8.492 APE11-dist-in 11.807 APE10-dist-in 6.351 APE9-dist-in 3.748 None None None XRAY 1.9 0.176 0.214 A 276 269 0 0 0 0 [[9, 265]] 1.0 6fck CAMK_CHEK1_HUMAN CAMK 2.2e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FSNA 3 280 476.0 A58:301 Type1 Active DFGin 6.932 14.164 BLAminus -128.61, 164.88 70.43, 97.56 -103.2, 24.55 286.11, 81.86 -65.53, -27.87 in-in in 8.797 Saltbr-in 2.69 HRD-in -73.22, -47.77 74.33, -1.49 in-in-in SNCiii in-in ActLoopNT-in 2.946 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.34, 169.78 APE9-dihe-na 114.52, -151.5 APE8-dihe-in -131.96, 119.56 APE8-rot-in 303.59 APE67-dihe-in -63.31, -19.83 -39.51, -51.75 APE12-dist-in 9.012 APE11-dist-in 11.629 APE10-dist-in 6.158 APE9-dist-in 3.27 None None None XRAY 2.1 0.178 0.217 A 278 270 8 0 0 0 [[9, 265]] 1.0 4fsn CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FSMA 3 280 476.0 HK1:301 Type1 Active DFGin 6.811 14.1 BLAminus -131.51, 171.53 65.39, 98.27 -106.32, 22.69 289.25, 89.34 -66.85, -29.11 in-in in 8.607 Saltbr-in 2.93 HRD-in -70.99, -49.26 75.29, 1.6 in-in-in SNCiii in-in ActLoopNT-in 2.967 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.1, 168.74 APE9-dihe-na 117.28, -151.19 APE8-dihe-in -134.15, 119.96 APE8-rot-in 302.46 APE67-dihe-in -60.14, -26.02 -38.68, -52.02 APE12-dist-in 9.051 APE11-dist-in 11.522 APE10-dist-in 5.959 APE9-dist-in 3.286 None None None XRAY 2.3 0.176 0.198 A 279 265 13 0 0 0 [[9, 265]] 1.0 4fsm CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FSRA 3 280 476.0 HKC:300 Type1 Active DFGin 6.871 14.281 BLAminus -126.58, 165.61 71.14, 98.24 -108.12, 23.67 292.66, 86.79 -61.1, -36.33 in-in in 9.154 Saltbr-in 2.844 HRD-in -68.1, -45.01 72.09, -2.18 in-in-in SNCiii in-in ActLoopNT-in 2.974 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.1, 148.18 APE9-dihe-na 118.31, -163.42 APE8-dihe-in -128.11, 114.92 APE8-rot-in 300.87 APE67-dihe-in -63.19, -17.37 -35.33, -51.8 APE12-dist-in 9.392 APE11-dist-in 11.198 APE10-dist-in 5.734 APE9-dist-in 3.337 None None None XRAY 2.5 0.177 0.198 A 279 269 9 0 0 0 [[9, 265]] 1.0 4fsr CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FSWA 3 280 476.0 HK6:301 Type1 Active DFGin 6.961 14.348 BLAminus -119.62, 151.67 67.77, 103.9 -105.99, 26.03 287.76, 84.88 -67.76, -25.89 in-in in 8.512 Saltbr-in 2.831 HRD-in -69.73, -47.61 75.54, -0.76 in-in-in SNCiii in-in ActLoopNT-in 2.928 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.8, 151.78 APE9-dihe-na 118.73, -158.26 APE8-dihe-in -133.6, 120.62 APE8-rot-in 303.14 APE67-dihe-in -61.67, -21.76 -43.39, -49.14 APE12-dist-in 9.169 APE11-dist-in 11.129 APE10-dist-in 5.487 APE9-dist-in 3.328 None None CSO168 XRAY 2.3 0.185 0.212 A 279 266 12 0 0 0 [[9, 265]] 1.0 4fsw CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FSYA 3 280 476.0 HK7:301 Type1 Active DFGin 7.037 14.406 BLAminus -133.9, 170.9 64.36, 92.44 -102.37, 28.4 289.81, 84.88 -65.52, -30.66 in-in in 8.364 Saltbr-in 2.762 HRD-in -71.27, -49.45 77.31, 1.06 in-in-in SNCiii in-in ActLoopNT-in 3.05 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.87, 166.71 APE9-dihe-na 112.85, -162.09 APE8-dihe-in -124.8, 131.06 APE8-rot-in 295.23 APE67-dihe-in -64.56, -25.01 -56.53, -41.12 APE12-dist-in 9.077 APE11-dist-in 11.423 APE10-dist-in 6.021 APE9-dist-in 3.356 None None CSO57 XRAY 2.3 0.183 0.226 A 279 268 10 0 0 0 [[9, 265]] 1.0 4fsy CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FSZA 3 280 476.0 HK8:301 Type1 Active DFGin 6.949 14.39 BLAminus -119.9, 153.43 66.34, 106.24 -107.62, 26.47 288.2, 87.05 -66.44, -34.56 in-in in 8.491 Saltbr-in 2.745 HRD-in -69.86, -48.51 74.46, 2.01 in-in-in SNCiii in-in ActLoopNT-in 3.012 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.3, 158.49 APE9-dihe-na 111.96, -155.49 APE8-dihe-in -132.22, 121.7 APE8-rot-in 308.64 APE67-dihe-in -64.81, -18.9 -40.6, -48.6 APE12-dist-in 9.243 APE11-dist-in 11.267 APE10-dist-in 5.605 APE9-dist-in 3.287 None None CSO57,CSO168 XRAY 2.3 0.175 0.22 A 279 270 8 0 0 0 [[9, 265]] 1.0 4fsz CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FT0A 3 280 476.0 HK9:301 Type1 Active DFGin 6.834 14.434 BLAminus -121.3, 156.17 66.51, 99.62 -103.86, 23.38 286.77, 86.68 -67.74, -22.21 in-in in 8.618 Saltbr-in 2.753 HRD-in -71.32, -48.66 76.71, -5.7 in-in-in SNCiii in-in ActLoopNT-in 2.961 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.21, 169.55 APE9-dihe-na 114.98, -146.91 APE8-dihe-in -133.85, 119.36 APE8-rot-in 306.38 APE67-dihe-in -61.82, -22.76 -40.65, -49.73 APE12-dist-in 8.984 APE11-dist-in 11.585 APE10-dist-in 5.992 APE9-dist-in 3.394 None None None XRAY 2.3 0.174 0.203 A 279 266 8 0 0 0 [[9, 265]] 1.0 4ft0 CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FT3A 2 280 476.0 H1K:301 Type1 Active DFGin 6.964 14.165 BLAminus -125.83, 166.69 67.61, 100.05 -109.27, 28.0 288.45, 82.38 -68.34, -27.81 in-in in 8.589 Saltbr-in 2.771 HRD-in -69.78, -44.73 71.85, -0.6 in-in-in SNCiii in-in ActLoopNT-in 3.03 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -140.81, 154.64 APE9-dihe-na 118.96, -155.02 APE8-dihe-in -132.3, 119.16 APE8-rot-in 307.95 APE67-dihe-in -63.69, -19.94 -39.85, -50.54 APE12-dist-in 9.145 APE11-dist-in 11.182 APE10-dist-in 5.755 APE9-dist-in 3.373 None None CSO168,CSO215 XRAY 2.5 0.17 0.213 A 279 272 7 0 0 0 [[9, 265]] 1.0 4ft3 CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FT5A 3 280 476.0 H2K:300 Type1 Active DFGin 6.953 14.266 BLAminus -127.2, 165.87 68.8, 94.55 -104.24, 26.6 287.26, 85.38 -67.4, -28.05 in-in in 8.449 Saltbr-in 2.762 HRD-in -69.57, -47.79 77.92, -5.64 in-in-in SNCiii in-in ActLoopNT-in 2.957 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.4, 157.75 APE9-dihe-na 110.01, -155.34 APE8-dihe-in -130.07, 123.38 APE8-rot-in 305.79 APE67-dihe-in -63.14, -20.95 -44.51, -49.54 APE12-dist-in 9.238 APE11-dist-in 11.505 APE10-dist-in 5.805 APE9-dist-in 3.423 None None None XRAY 2.4 0.18 0.223 A 279 265 13 0 0 0 [[9, 265]] 1.0 4ft5 CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FT7A 3 280 476.0 H3K:301 Type1 Active DFGin 6.917 14.254 BLAminus -123.26, 155.01 65.6, 104.61 -106.93, 24.92 287.72, 82.64 -63.39, -27.36 in-in in 8.745 Saltbr-in 2.773 HRD-in -68.13, -44.52 71.13, 4.67 in-in-in SNCiii in-in ActLoopNT-in 2.999 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.74, 167.5 APE9-dihe-na 117.49, -151.06 APE8-dihe-in -131.37, 120.33 APE8-rot-in 307.45 APE67-dihe-in -64.01, -19.31 -40.36, -50.09 APE12-dist-in 9.056 APE11-dist-in 11.569 APE10-dist-in 6.056 APE9-dist-in 3.295 None None None XRAY 2.2 0.172 0.195 A 279 270 8 0 0 0 [[9, 265]] 1.0 4ft7 CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FT9A 2 280 476.0 H4K:300 Type1 Active DFGin 7.007 14.251 BLAminus -126.66, 162.85 64.17, 98.66 -102.76, 25.95 287.5, 82.94 -63.78, -29.14 in-in in 8.707 Saltbr-in 2.683 HRD-in -70.59, -46.02 71.89, 2.79 in-in-in SNCiii in-in ActLoopNT-in 3.015 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.14, 167.54 APE9-dihe-na 119.1, -145.69 APE8-dihe-in -134.13, 123.1 APE8-rot-in 304.24 APE67-dihe-in -62.3, -22.11 -43.6, -50.05 APE12-dist-in 8.945 APE11-dist-in 11.72 APE10-dist-in 6.162 APE9-dist-in 3.283 None None None XRAY 2.2 0.163 0.206 A 279 270 9 0 0 0 [[9, 265]] 1.0 4ft9 CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FTAA 3 280 476.0 H5K:301 Type1 Active DFGin 7.033 14.229 BLAminus -115.22, 157.1 65.07, 98.74 -104.16, 26.55 287.97, 87.34 -67.17, -28.17 in-in in 8.609 Saltbr-in 2.74 HRD-in -69.34, -47.6 75.8, -1.19 in-in-in SNCiii in-in ActLoopNT-in 2.95 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.7, 154.16 APE9-dihe-na 113.98, -159.29 APE8-dihe-in -129.33, 114.8 APE8-rot-in 303.04 APE67-dihe-in -62.29, -17.92 -34.19, -52.76 APE12-dist-in 9.19 APE11-dist-in 11.217 APE10-dist-in 5.669 APE9-dist-in 3.272 None None CSO168 XRAY 2.4 0.172 0.211 A 279 265 13 0 0 0 [[9, 265]] 1.0 4fta CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FTCA 2 280 476.0 H6K:301 Type1 Active DFGin 7.007 14.217 BLAminus -124.04, 161.25 66.03, 97.49 -103.03, 25.51 288.01, 85.12 -63.04, -32.4 in-in in 8.584 Saltbr-in 2.753 HRD-in -73.06, -46.23 73.2, 0.43 in-in-in SNCiii in-in ActLoopNT-in 2.991 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.76, 151.76 APE9-dihe-na 120.55, -155.44 APE8-dihe-in -134.19, 118.99 APE8-rot-in 305.56 APE67-dihe-in -65.13, -17.34 -40.64, -50.7 APE12-dist-in 9.196 APE11-dist-in 11.308 APE10-dist-in 5.709 APE9-dist-in 3.312 None None CSO168 XRAY 2.0 0.17 0.194 A 279 267 12 0 0 0 [[9, 265]] 1.0 4ftc CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FTIA 3 279 476.0 H7K:301 Type1 Active DFGin 6.938 14.265 BLAminus -131.71, 165.12 68.45, 90.85 -99.85, 27.35 288.14, 85.15 -66.83, -26.06 in-in in 8.757 Saltbr-in 2.669 HRD-in -69.83, -48.6 74.25, 0.8 in-in-in SNCiii in-in ActLoopNT-in 2.929 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.15, 166.8 APE9-dihe-na 118.02, -149.51 APE8-dihe-in -134.76, 120.08 APE8-rot-in 303.98 APE67-dihe-in -63.85, -21.57 -41.85, -47.71 APE12-dist-in 8.948 APE11-dist-in 11.514 APE10-dist-in 6.1 APE9-dist-in 3.37 None None None XRAY 2.2 0.175 0.194 A 279 270 7 0 0 0 [[9, 265]] 1.0 4fti CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FTJA 3 279 476.0 H8K:301 Type1 Active DFGin 6.858 14.158 BLAminus -126.08, 172.19 64.35, 93.91 -103.12, 23.88 288.19, 87.63 -63.51, -29.53 in-in in 8.607 Saltbr-in 2.739 HRD-in -70.61, -46.43 71.78, 1.15 in-in-in SNCiii in-in ActLoopNT-in 3.007 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.56, 169.93 APE9-dihe-na 115.22, -147.36 APE8-dihe-in -135.06, 117.23 APE8-rot-in 306.8 APE67-dihe-in -63.27, -20.35 -37.52, -49.27 APE12-dist-in 9.024 APE11-dist-in 11.658 APE10-dist-in 6.163 APE9-dist-in 3.437 None None None XRAY 2.2 0.182 0.205 A 279 266 11 0 0 0 [[9, 265]] 1.0 4ftj CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FTOA 3 271 476.0 3HK:301 Type1 Active DFGin 6.959 14.238 BLAminus -127.57, 164.38 64.01, 101.47 -105.82, 25.9 289.5, 84.0 -68.68, -24.99 in-in in 8.734 Saltbr-in 2.783 HRD-in -68.98, -46.7 71.08, 0.02 in-in-in SNCiii in-in ActLoopNT-in 2.978 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.78, 154.6 APE9-dihe-na 111.8, -161.39 APE8-dihe-in -129.05, 120.57 APE8-rot-in 307.69 APE67-dihe-in -63.78, -20.08 -41.73, -50.26 APE12-dist-in 9.252 APE11-dist-in 11.186 APE10-dist-in 5.713 APE9-dist-in 3.299 None None None XRAY 2.1 0.181 0.195 A 279 252 17 0 0 0 [[9, 265]] 1.0 4fto CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FTQA 3 270 476.0 4HK:301 Type1 Active DFGin 6.948 14.167 BLAminus -121.37, 155.84 67.1, 99.27 -103.93, 23.74 289.44, 84.22 -64.63, -29.39 in-in in 8.644 Saltbr-in 2.729 HRD-in -73.53, -44.86 70.84, 1.85 in-in-in SNCiii in-in ActLoopNT-in 2.971 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.76, 150.17 APE9-dihe-na 119.72, -160.49 APE8-dihe-in -131.7, 116.38 APE8-rot-in 301.57 APE67-dihe-in -62.8, -20.14 -38.44, -50.62 APE12-dist-in 9.157 APE11-dist-in 11.155 APE10-dist-in 5.573 APE9-dist-in 3.312 None None CSO168 XRAY 2.0 0.186 0.22 A 279 255 13 0 0 0 [[9, 265]] 1.0 4ftq CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FTRA 3 271 476.0 5HK:301 Type1 Active DFGin 6.943 14.278 BLAminus -123.21, 153.43 70.58, 95.78 -100.72, 25.84 289.71, 85.74 -70.61, -24.38 in-in in 8.442 Saltbr-in 2.79 HRD-in -69.02, -49.81 76.72, 0.2 in-in-in SNCiii in-in ActLoopNT-in 2.986 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.88, 153.77 APE9-dihe-na 114.4, -160.46 APE8-dihe-in -130.66, 117.37 APE8-rot-in 305.19 APE67-dihe-in -61.47, -21.96 -37.98, -50.68 APE12-dist-in 9.214 APE11-dist-in 11.239 APE10-dist-in 5.761 APE9-dist-in 3.341 None None None XRAY 2.25 0.174 0.214 A 279 258 11 0 0 0 [[9, 265]] 1.0 4ftr CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FTTA 3 280 476.0 6HK:301 Type1 Active DFGin 6.94 14.218 BLAminus -122.83, 153.42 68.27, 105.19 -108.24, 23.4 287.92, 83.92 -66.27, -24.53 in-in in 8.543 Saltbr-in 2.745 HRD-in -71.13, -47.05 73.89, 3.88 in-in-in SNCiii in-in ActLoopNT-in 3.034 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.81, 170.65 APE9-dihe-na 115.8, -149.58 APE8-dihe-in -133.84, 119.22 APE8-rot-in 302.97 APE67-dihe-in -62.62, -20.85 -38.98, -49.57 APE12-dist-in 9.301 APE11-dist-in 11.764 APE10-dist-in 6.151 APE9-dist-in 3.3 None None None XRAY 2.3 0.173 0.215 A 279 266 12 0 0 0 [[9, 265]] 1.0 4ftt CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FTUA 3 280 476.0 7HK:301 Type1 Active DFGin 7.004 14.209 BLAminus -122.0, 154.39 66.73, 96.53 -100.93, 26.02 289.18, 80.78 -66.13, -27.5 in-in in 8.572 Saltbr-in 2.735 HRD-in -67.38, -44.96 72.12, 5.18 in-in-in SNCiii in-in ActLoopNT-in 3.057 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.18, 152.58 APE9-dihe-na 115.82, -158.26 APE8-dihe-in -130.91, 118.67 APE8-rot-in 304.9 APE67-dihe-in -60.79, -23.34 -39.91, -50.93 APE12-dist-in 9.326 APE11-dist-in 11.31 APE10-dist-in 5.899 APE9-dist-in 3.324 None None None XRAY 2.1 0.191 0.21 A 279 270 8 0 0 0 [[9, 265]] 1.0 4ftu CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4GH2A 3 280 476.0 HK0:301 Type1 Active DFGin 7.051 14.226 BLAminus -123.38, 153.93 69.02, 96.41 -100.38, 23.56 288.59, 84.72 -64.85, -27.37 in-in in 8.309 Saltbr-in 2.895 HRD-in -70.31, -46.53 72.01, 0.52 in-in-in SNCiii in-in ActLoopNT-in 2.96 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.99, 152.09 APE9-dihe-na 116.77, -155.33 APE8-dihe-in -133.62, 120.42 APE8-rot-in 304.79 APE67-dihe-in -64.36, -18.36 -40.72, -49.54 APE12-dist-in 9.236 APE11-dist-in 11.437 APE10-dist-in 5.983 APE9-dist-in 3.279 None None CSO168,CSO215 XRAY 2.03 0.165 0.192 A 279 268 10 0 0 0 [[9, 265]] 1.0 4gh2 CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
1NVQA 3 273 476.0 UCN:400 Type1 Active DFGin 7.103 14.396 BLAminus -125.86, 163.9 66.03, 91.68 -101.2, 28.08 286.61, 74.15 -67.93, -18.15 in-in in 8.517 Saltbr-in 2.873 HRD-in -72.89, -40.79 69.72, -3.58 in-in-in SNCiii in-in ActLoopNT-in 2.963 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.67, 158.23 APE9-dihe-na 121.41, -157.73 APE8-dihe-in -131.99, 117.0 APE8-rot-in 305.5 APE67-dihe-in -60.55, -25.67 -32.5, -52.91 APE12-dist-in 9.297 APE11-dist-in 11.514 APE10-dist-in 5.747 APE9-dist-in 3.379 None None None XRAY 2.0 0.206 0.234 A 289 264 7 0 0 0 [[9, 265]] 1.0 1nvq CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
1NVRA 3 273 476.0 STU:400 Type1 Active DFGin 7.007 14.466 BLAminus -138.12, 170.91 63.58, 88.44 -97.82, 26.51 284.37, 82.9 -65.94, -21.37 in-in in 8.834 Saltbr-in 3.325 HRD-in -77.73, -42.26 72.42, 0.07 in-in-in SNCiii in-in ActLoopNT-in 2.892 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.96, 168.99 APE9-dihe-na 123.47, -148.6 APE8-dihe-in -135.84, 118.76 APE8-rot-in 301.9 APE67-dihe-in -60.54, -22.99 -38.52, -52.15 APE12-dist-in 8.986 APE11-dist-in 11.773 APE10-dist-in 6.22 APE9-dist-in 3.344 None None None XRAY 1.8 0.193 0.226 A 289 264 7 0 0 0 [[9, 265]] 1.0 1nvr CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
1NVSA 3 273 476.0 UCM:400 Type1 Active DFGin 6.948 14.327 BLAminus -124.54, 157.02 67.79, 99.69 -105.15, 29.66 290.94, 77.78 -68.62, -19.97 in-in in 8.855 Saltbr-in 2.994 HRD-in -72.71, -44.77 71.02, 1.77 in-in-in SNCiii in-in ActLoopNT-in 2.979 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.31, 168.53 APE9-dihe-na 121.14, -147.06 APE8-dihe-in -136.26, 119.24 APE8-rot-in 304.24 APE67-dihe-in -59.99, -25.66 -37.19, -52.23 APE12-dist-in 9.001 APE11-dist-in 11.829 APE10-dist-in 6.273 APE9-dist-in 3.311 None None None XRAY 1.8 0.232 0.255 A 289 264 7 0 0 0 [[9, 265]] 1.0 1nvs CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2WMQA 7 269 476.0 ZYQ:1270 Type1 Active DFGin 6.796 14.301 BLAminus -129.03, 145.77 85.94, 84.92 -97.17, 15.57 294.92, 82.28 -58.59, -22.48 in-in in 8.846 Saltbr-in 2.95 HRD-in -73.66, -48.07 79.85, -4.75 in-in-in SNCiii in-in ActLoopNT-in 2.997 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -150.83, 146.62 APE9-dihe-na 120.81, -140.09 APE8-dihe-in -140.39, 114.38 APE8-rot-in 303.0 APE67-dihe-in -66.52, -23.18 -38.86, -48.73 APE12-dist-in 9.438 APE11-dist-in 11.69 APE10-dist-in 6.292 APE9-dist-in 3.682 None None None XRAY 2.48 0.222 0.25 A 289 246 17 0 0 0 [[9, 265]] 1.0 2wmq CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2WMRA 7 270 476.0 ZYR:1271 Type1 Active DFGin 6.788 14.246 BLAminus -123.65, 155.63 63.04, 103.09 -106.02, 13.15 292.74, 86.07 -58.1, -20.3 in-in in 8.801 Saltbr-in 3.087 HRD-in -72.49, -46.78 75.8, -4.43 in-in-in SNCiii in-in ActLoopNT-in 3.033 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.91, 174.03 APE9-dihe-na 103.24, -160.08 APE8-dihe-in -132.56, 126.77 APE8-rot-in 295.16 APE67-dihe-in -69.57, -25.74 -49.21, -44.24 APE12-dist-in 9.393 APE11-dist-in 11.479 APE10-dist-in 5.803 APE9-dist-in 3.312 None None None XRAY 2.43 0.211 0.26 A 289 254 10 0 0 0 [[9, 265]] 1.0 2wmr CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2WMSA 7 270 476.0 ZYS:1271 Type1 Active DFGin 6.833 14.097 BLAminus -120.52, 146.54 79.14, 90.95 -98.33, 31.19 298.09, 80.64 -65.06, -38.38 in-in in 8.545 Saltbr-in 3.215 HRD-in -69.44, -50.22 83.54, -10.58 in-in-in SNCiii in-in ActLoopNT-in 2.976 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.01, 158.54 APE9-dihe-na 117.42, -150.3 APE8-dihe-in -138.73, 119.72 APE8-rot-in 292.61 APE67-dihe-in -66.29, -34.03 -39.39, -47.99 APE12-dist-in 9.422 APE11-dist-in 11.326 APE10-dist-in 5.674 APE9-dist-in 3.574 None None None XRAY 2.7 0.225 0.259 A 289 243 21 0 0 0 [[9, 265]] 1.0 2wms CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2WMTA 8 270 476.0 ZYT:1271 Type1 Active DFGin 6.785 14.281 BLAminus -125.63, 146.24 75.37, 98.66 -104.06, 17.98 297.2, 81.75 -49.27, -35.19 in-in in 8.635 Saltbr-in 3.235 HRD-in -66.09, -46.05 77.82, -7.26 in-in-in SNCiii in-in ActLoopNT-in 3.003 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.87, 162.85 APE9-dihe-na 85.87, -159.47 APE8-dihe-in -114.07, 140.35 APE8-rot-in 306.26 APE67-dihe-in -62.65, -35.9 -60.11, -40.99 APE12-dist-in 9.654 APE11-dist-in 11.321 APE10-dist-in 6.292 APE9-dist-in 3.348 None None None XRAY 2.55 0.216 0.257 A 289 248 15 0 0 0 [[9, 265]] 1.0 2wmt CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2WMUA 9 270 476.0 ZYU:1271 Type1 Active DFGin 6.761 14.225 BLAminus -124.58, 149.67 73.48, 98.24 -107.24, 22.24 291.36, 85.36 -63.37, -31.63 in-in in 8.708 Saltbr-in 3.267 HRD-in -66.01, -47.65 80.18, -8.04 in-in-in SNCiii in-in ActLoopNT-in 2.897 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.94, 156.42 APE9-dihe-na 115.63, -158.82 APE8-dihe-in -128.41, 142.86 APE8-rot-in 304.02 APE67-dihe-in -62.86, -36.77 -61.36, -43.1 APE12-dist-in 9.56 APE11-dist-in 11.344 APE10-dist-in 5.724 APE9-dist-in 3.622 None None None XRAY 2.6 0.232 0.261 A 289 246 16 0 0 0 [[9, 265]] 1.0 2wmu CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2WMVA 7 270 476.0 ZYV:1271 Type1 Active DFGin 6.82 14.229 BLAminus -124.93, 150.62 73.24, 97.26 -104.78, 26.94 292.36, 84.42 -64.24, -27.28 in-in in 8.594 Saltbr-in 2.992 HRD-in -67.11, -46.21 78.67, -3.53 in-in-in SNCiii in-in ActLoopNT-in 3.098 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -140.54, 147.19 APE9-dihe-na 131.68, -159.35 APE8-dihe-in -132.74, 118.07 APE8-rot-in 302.64 APE67-dihe-in -64.16, -20.61 -42.4, -49.2 APE12-dist-in 9.241 APE11-dist-in 11.599 APE10-dist-in 6.167 APE9-dist-in 3.648 None None None XRAY 2.009 0.215 0.241 A 289 251 13 0 0 0 [[9, 265]] 1.0 2wmv CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2WMWA 7 269 476.0 ZYW:1270 Type1 Active DFGin 6.909 14.423 BLAminus -138.43, 150.75 76.46, 89.37 -98.01, 21.58 291.28, 80.82 -54.99, -32.89 in-in in 8.443 Saltbr-in 2.967 HRD-in -68.78, -46.97 76.52, -3.86 in-in-in SNCiii in-in ActLoopNT-in 2.869 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.16, 158.72 APE9-dihe-na 118.12, -156.78 APE8-dihe-in -132.71, 131.43 APE8-rot-in 292.41 APE67-dihe-in -67.92, -22.67 -51.42, -45.51 APE12-dist-in 9.365 APE11-dist-in 11.322 APE10-dist-in 5.785 APE9-dist-in 3.46 None None None XRAY 2.43 0.23 0.25 A 289 247 16 0 0 0 [[9, 265]] 1.0 2wmw CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2WMXA 7 269 476.0 ZY6:1270 Type1 Active DFGin 6.909 14.421 BLAminus -138.41, 150.78 76.37, 89.37 -97.97, 21.58 291.28, 80.83 -54.97, -32.94 in-in in 8.441 Saltbr-in 2.966 HRD-in -68.74, -47.03 76.58, -3.91 in-in-in SNCiii in-in ActLoopNT-in 2.869 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -120.46, 168.26 APE9-dihe-na 106.57, -155.31 APE8-dihe-in -139.79, 119.56 APE8-rot-in 301.17 APE67-dihe-in -67.05, -27.81 -41.76, -47.11 APE12-dist-in 9.425 APE11-dist-in 11.466 APE10-dist-in 5.846 APE9-dist-in 3.437 None None None XRAY 2.45 0.22 0.244 A 289 248 15 0 0 0 [[9, 265]] 1.0 2wmx CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2X8DA 2 281 476.0 X8D:1282 Type1 Active DFGin 6.877 14.222 BLAminus -125.34, 145.96 75.16, 98.27 -103.12, 27.2 290.54, 84.91 -65.81, -25.94 in-in in 8.844 Saltbr-in 2.735 HRD-in -72.7, -49.53 78.44, 1.87 in-in-in SNCiii in-in ActLoopNT-in 2.991 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -162.58, 168.95 APE9-dihe-na 117.28, -146.64 APE8-dihe-in -140.7, 121.77 APE8-rot-in 299.91 APE67-dihe-in -64.55, -22.3 -47.16, -49.22 APE12-dist-in 8.928 APE11-dist-in 11.939 APE10-dist-in 6.34 APE9-dist-in 3.35 None None None XRAY 1.9 0.162 0.192 A 289 280 0 0 0 0 [[9, 265]] 1.0 2x8d CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2X8IA 2 269 476.0 X8I:1270 Type1 Active DFGin 6.776 14.083 BLAminus -130.04, 149.82 73.34, 96.28 -103.39, 27.63 292.92, 82.96 -65.75, -24.88 in-in in 8.793 Saltbr-in 2.576 HRD-in -77.47, -44.34 72.43, -2.94 in-in-in SNCiii in-in ActLoopNT-in 2.981 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -117.06, -13.81 APE9-dihe-na -73.16, 171.96 APE8-dihe-in -80.79, 122.28 APE8-rot-in 306.49 APE67-dihe-in -61.85, -17.2 -49.93, -44.93 APE12-dist-in 8.562 APE11-dist-in 11.543 APE10-dist-in 5.779 APE9-dist-in 3.699 None None None XRAY 1.92 0.189 0.224 A 289 261 7 0 0 0 [[9, 265]] 1.0 2x8i CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2XEYA 6 269 476.0 YVQ:1270 Type1 Active DFGin 6.804 14.351 BLAminus -120.46, 134.88 92.9, 102.51 -108.36, 19.57 294.43, 85.01 -58.71, -37.33 in-in in 8.628 Saltbr-in 2.76 HRD-in -66.52, -46.0 79.92, -6.26 in-in-in SNCiii in-in ActLoopNT-in 3.069 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.81, 159.95 APE9-dihe-na 131.23, -158.32 APE8-dihe-in -120.65, 138.4 APE8-rot-in 296.68 APE67-dihe-in -63.86, -44.09 -60.1, -42.19 APE12-dist-in 9.709 APE11-dist-in 11.471 APE10-dist-in 5.99 APE9-dist-in 3.662 None None None XRAY 2.7 0.222 0.266 A 289 252 12 0 0 0 [[9, 265]] 1.0 2xey CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2XEZA 7 270 476.0 XEZ:1271 Type1 Active DFGin 6.917 14.25 BLAminus -133.54, 142.66 88.28, 99.32 -106.34, 26.02 290.91, 85.99 -64.69, -27.13 in-in in 8.597 Saltbr-in 3.054 HRD-in -65.08, -46.22 76.5, -0.68 in-in-in SNCiii in-in ActLoopNT-in 3.013 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.97, 168.01 APE9-dihe-na 96.0, -161.59 APE8-dihe-in -119.9, 136.16 APE8-rot-in 305.18 APE67-dihe-in -63.7, -42.45 -59.06, -41.87 APE12-dist-in 9.071 APE11-dist-in 11.462 APE10-dist-in 6.133 APE9-dist-in 3.519 None None None XRAY 2.25 0.211 0.237 A 289 249 15 0 0 0 [[9, 265]] 1.0 2xez CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2XF0A 4 270 476.0 4UB:1271 Type1 Active DFGin 6.962 14.334 BLAminus -127.76, 149.31 66.74, 102.17 -107.04, 28.33 293.33, 77.96 -65.23, -24.59 in-in in 8.573 Saltbr-in 2.894 HRD-in -65.87, -48.49 79.64, -2.44 in-in-in SNCiii in-in ActLoopNT-in 3.089 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.69, -175.12 APE9-dihe-na 97.78, -156.38 APE8-dihe-in -122.87, 129.03 APE8-rot-in 303.15 APE67-dihe-in -54.36, -33.92 -44.93, -56.27 APE12-dist-in 9.385 APE11-dist-in 11.503 APE10-dist-in 6.16 APE9-dist-in 3.449 None None None XRAY 2.4 0.204 0.244 A 289 251 16 0 0 0 [[9, 265]] 1.0 2xf0 CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2YDIA 2 281 476.0 YDI:1282 Type1 Active DFGin 6.976 13.97 BLAminus -126.3, 150.36 77.21, 97.59 -103.07, 23.89 288.63, 85.13 -67.84, -26.49 in-in in 8.786 Saltbr-in 2.768 HRD-in -77.6, -45.08 76.82, -1.13 in-in-in SNCiii in-in ActLoopNT-in 2.977 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -162.57, 169.22 APE9-dihe-na 113.97, -148.03 APE8-dihe-in -138.83, 121.25 APE8-rot-in 303.94 APE67-dihe-in -62.29, -21.07 -47.63, -48.12 APE12-dist-in 8.918 APE11-dist-in 12.019 APE10-dist-in 6.433 APE9-dist-in 3.354 None None None XRAY 1.6 0.168 0.2 A 289 280 0 0 0 0 [[9, 265]] 1.0 2ydi CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2YM3A 8 270 476.0 YM3:1271 Type1 Active DFGin 6.945 14.55 BLAminus -124.53, 145.82 77.8, 96.14 -106.02, 30.03 290.55, 85.33 -72.09, -23.02 in-in in 8.634 Saltbr-in 2.756 HRD-in -74.61, -45.33 76.04, 0.41 in-in-in SNCiii in-in ActLoopNT-in 3.017 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.51, 177.11 APE9-dihe-na 108.64, -151.07 APE8-dihe-in -133.43, 124.53 APE8-rot-in 300.4 APE67-dihe-in -62.52, -16.87 -44.07, -52.65 APE12-dist-in 9.576 APE11-dist-in 11.772 APE10-dist-in 6.288 APE9-dist-in 3.279 None None None XRAY 2.007 0.179 0.203 A 289 247 16 0 0 0 [[9, 265]] 1.0 2ym3 CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2YM4A 4 270 476.0 4YM:1271 Type1 Active DFGin 6.943 14.899 BLAminus -122.13, 155.72 68.31, 93.18 -103.18, 30.94 289.55, 80.73 -72.79, -19.76 in-in in 8.664 Saltbr-in 3.501 HRD-in -69.97, -47.22 81.59, -11.8 in-in-in SNCiii in-in ActLoopNT-in 3.038 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.93, 148.67 APE9-dihe-na 118.08, -148.67 APE8-dihe-in -131.7, 127.55 APE8-rot-in 303.59 APE67-dihe-in -61.62, -16.06 -47.52, -50.41 APE12-dist-in 9.702 APE11-dist-in 11.482 APE10-dist-in 5.987 APE9-dist-in 3.547 None None None XRAY 2.35 0.206 0.247 A 289 251 16 0 0 0 [[9, 265]] 1.0 2ym4 CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2YM8A 8 270 476.0 YM8:1271 Type1 Active DFGin 6.918 14.484 BLAminus -119.81, 160.75 69.41, 92.68 -106.25, 26.79 288.47, 85.52 -68.01, -21.81 in-in in 8.463 Saltbr-in 2.642 HRD-in -74.85, -49.07 83.35, -9.52 in-in-in SNCiii in-in ActLoopNT-in 2.933 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.5, 170.9 APE9-dihe-na 117.99, -150.41 APE8-dihe-in -140.36, 119.04 APE8-rot-in 303.38 APE67-dihe-in -63.4, -22.13 -41.5, -51.94 APE12-dist-in 9.391 APE11-dist-in 11.695 APE10-dist-in 6.202 APE9-dist-in 3.459 None None None XRAY 2.07 0.191 0.231 A 289 246 17 0 0 0 [[9, 265]] 1.0 2ym8 CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4HYHA 4 272 476.0 1AM:301 Type1 Active DFGin 6.906 14.218 BLAminus -128.98, 166.78 69.3, 88.21 -100.12, 24.75 289.06, 83.24 -68.3, -20.44 in-in in 9.041 Saltbr-in 2.497 HRD-in -78.56, -45.08 75.8, -4.8 in-in-in SNCiii in-in ActLoopNT-in 2.947 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.65, 153.88 APE9-dihe-na 129.07, -156.46 APE8-dihe-in -132.58, 121.58 APE8-rot-in 303.73 APE67-dihe-in -60.58, -22.44 -37.91, -54.78 APE12-dist-in 9.063 APE11-dist-in 11.335 APE10-dist-in 5.834 APE9-dist-in 3.455 None None None XRAY 1.7 0.204 0.226 A 289 263 6 0 0 0 [[9, 265]] 1.0 4hyh CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4HYIA 3 274 476.0 1AO:304 Type1 Active DFGin 6.971 14.263 BLAminus -133.52, 170.26 67.21, 89.03 -100.55, 26.73 288.63, 81.95 -69.01, -20.83 in-in in 8.703 Saltbr-in 2.8 HRD-in -76.04, -45.38 76.0, -0.31 in-in-in SNCiii in-in ActLoopNT-in 2.945 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -165.36, 169.96 APE9-dihe-na 118.31, -154.09 APE8-dihe-in -134.47, 119.9 APE8-rot-in 301.58 APE67-dihe-in -63.47, -20.04 -40.17, -52.51 APE12-dist-in 8.794 APE11-dist-in 11.802 APE10-dist-in 6.333 APE9-dist-in 3.478 None None None XRAY 1.399 0.183 0.202 A 289 269 3 0 0 0 [[9, 265]] 1.0 4hyi CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
1ZLTA 2 276 476.0 HYM:400 Type1 Active DFGin 6.614 13.867 BLAminus -126.38, 168.93 65.17, 92.12 -102.75, 29.34 295.7, 86.46 -65.38, -26.93 in-in in 8.567 Saltbr-in 3.001 HRD-in -74.75, -46.48 73.58, -1.97 in-in-in SNCiii in-in ActLoopNT-in 2.901 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -147.22, 155.91 APE9-dihe-na 115.18, -153.21 APE8-dihe-in -135.77, 120.73 APE8-rot-in 302.12 APE67-dihe-in -61.41, -27.81 -37.92, -49.99 APE12-dist-in 9.026 APE11-dist-in 11.822 APE10-dist-in 6.386 APE9-dist-in 3.233 None None None XRAY 1.74 0.227 0.265 A 295 272 3 0 0 0 [[9, 265]] 1.0 1zlt CAMK_CHEK1_HUMAN CAMK 2.8e-71 245.8 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2GDOA 1 273 476.0 12C:298 Type1 Active DFGin 6.959 13.949 BLAminus -127.91, 159.13 71.31, 115.52 -129.98, 13.98 288.91, 76.03 -55.88, -6.97 in-in in 8.642 Saltbr-in 2.586 HRD-in -77.91, -46.29 78.14, 3.28 in-in-in SNCiii in-in ActLoopNT-in 2.935 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -164.47, 167.51 APE9-dihe-na 121.4, -118.02 APE8-dihe-in -163.54, 121.61 APE8-rot-in 299.5 APE67-dihe-in -61.0, -21.04 -40.53, -57.04 APE12-dist-in 9.394 APE11-dist-in 12.077 APE10-dist-in 6.613 APE9-dist-in 3.333 None None None XRAY 3.0 0.206 0.259 A 295 269 4 0 0 0 [[9, 265]] 1.0 2gdo CAMK_CHEK1_HUMAN CAMK 2.8e-71 245.8 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2BR1A 2 276 476.0 PFP:1277 Type1 Active DFGin 6.793 14.123 BLAminus -130.59, 159.96 73.94, 93.36 -102.22, 21.99 289.33, 86.45 -62.48, -28.03 in-in in 8.999 Saltbr-in 2.892 HRD-in -73.11, -44.22 70.56, 4.17 in-in-in SNCiii in-in ActLoopNT-in 2.973 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.65, 173.48 APE9-dihe-na 118.03, -148.27 APE8-dihe-in -138.18, 120.92 APE8-rot-in 298.16 APE67-dihe-in -63.38, -22.4 -48.9, -47.72 APE12-dist-in 9.018 APE11-dist-in 11.717 APE10-dist-in 6.306 APE9-dist-in 3.471 None None None XRAY 2.0 0.163 0.226 A 297 272 3 0 0 0 [[9, 265]] 1.0 2br1 CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2BRBA 2 276 476.0 PFQ:1277 Type1 Active DFGin 6.777 14.206 BLAminus -124.91, 167.19 62.16, 91.6 -103.57, 28.61 293.18, 87.6 -71.38, -21.49 in-in in 8.788 Saltbr-in 3.085 HRD-in -74.34, -47.68 74.97, -0.21 in-in-in SNCiii in-in ActLoopNT-in 2.963 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -149.17, 171.97 APE9-dihe-na 115.21, -150.83 APE8-dihe-in -129.85, 123.76 APE8-rot-in 305.36 APE67-dihe-in -64.1, -22.07 -43.43, -50.05 APE12-dist-in 9.134 APE11-dist-in 11.642 APE10-dist-in 6.016 APE9-dist-in 3.293 None None None XRAY 2.1 0.243 0.272 A 297 272 3 0 0 0 [[9, 265]] 1.0 2brb CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2BRGA 7 269 476.0 DFY:1270 Type1 Active DFGin 6.757 14.35 BLAminus -136.08, 139.9 86.09, 98.75 -105.44, 16.17 289.83, 90.07 -62.74, -23.98 in-in in 8.947 Saltbr-in 2.723 HRD-in -77.38, -46.1 73.52, -1.4 in-in-in SNCiii in-in ActLoopNT-in 2.888 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -164.14, 173.86 APE9-dihe-na 118.8, -153.5 APE8-dihe-in -126.63, 115.38 APE8-rot-in 292.75 APE67-dihe-in -63.0, -12.21 -42.58, -47.41 APE12-dist-in 9.002 APE11-dist-in 11.592 APE10-dist-in 6.309 APE9-dist-in 3.574 None None None XRAY 2.1 0.212 0.294 A 297 257 6 0 0 0 [[9, 265]] 1.0 2brg CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2BRHA 6 271 476.0 DFW:1272 Type1 Active DFGin 6.959 14.661 BLAminus -140.73, 143.43 79.42, 92.98 -97.12, 17.45 288.86, 83.71 -48.34, -29.94 in-in in 9.146 Saltbr-in 2.704 HRD-in -78.41, -40.27 70.76, 3.5 in-in-in SNCiii in-in ActLoopNT-in 2.887 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.83, 172.27 APE9-dihe-na 128.03, -148.83 APE8-dihe-in -135.7, 117.05 APE8-rot-in 297.03 APE67-dihe-in -64.11, -20.87 -41.67, -50.92 APE12-dist-in 9.609 APE11-dist-in 11.51 APE10-dist-in 6.147 APE9-dist-in 3.48 None None None XRAY 2.1 0.183 0.257 A 297 257 9 0 0 0 [[9, 265]] 1.0 2brh CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2BRMA 7 274 476.0 DFZ:1275 Type1 Active DFGin 6.84 14.038 BLAminus -135.86, 168.58 63.75, 91.55 -106.09, 29.22 295.16, 87.09 -76.07, -17.33 in-in in 8.848 Saltbr-in 2.709 HRD-in -72.25, -46.84 78.63, -1.49 in-in-in SNCiii in-in ActLoopNT-in 3.073 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.66, 173.98 APE9-dihe-na 111.72, -142.65 APE8-dihe-in -137.48, 130.31 APE8-rot-in 300.44 APE67-dihe-in -56.88, -34.55 -54.89, -47.74 APE12-dist-in 9.027 APE11-dist-in 11.79 APE10-dist-in 6.3 APE9-dist-in 3.432 None None None XRAY 2.2 0.228 0.281 A 297 263 5 0 0 0 [[9, 265]] 1.0 2brm CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2BRNA 6 276 476.0 DF1:1277 Type1 Active DFGin 6.912 14.137 BLAminus -116.25, 147.52 75.05, 98.47 -108.38, 27.03 293.17, 87.0 -64.45, -36.89 in-in in 8.657 Saltbr-in 2.943 HRD-in -68.02, -45.32 74.19, 6.58 in-in-in SNCiii in-in ActLoopNT-in 2.967 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.95, 164.76 APE9-dihe-na 125.6, -149.2 APE8-dihe-in -128.12, 132.65 APE8-rot-in 303.29 APE67-dihe-in -63.75, -28.46 -56.16, -47.84 APE12-dist-in 9.268 APE11-dist-in 11.654 APE10-dist-in 6.198 APE9-dist-in 3.462 None None None XRAY 2.8 0.207 0.285 A 297 268 3 0 0 0 [[9, 265]] 1.0 2brn CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2BROA 2 276 476.0 DF2:1277 Type1 Active DFGin 6.757 14.064 BLAminus -133.35, 154.27 78.19, 90.51 -99.21, 21.9 296.19, 85.72 -64.77, -25.64 in-in in 8.908 Saltbr-in 2.81 HRD-in -70.81, -47.49 77.16, 3.76 in-in-in SNCiii in-in ActLoopNT-in 2.985 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.25, 173.9 APE9-dihe-na 116.88, -150.3 APE8-dihe-in -136.74, 118.66 APE8-rot-in 294.36 APE67-dihe-in -57.57, -22.87 -44.25, -49.17 APE12-dist-in 9.937 APE11-dist-in 11.741 APE10-dist-in 6.267 APE9-dist-in 3.477 None None None XRAY 2.2 0.202 0.279 A 297 272 3 0 0 0 [[9, 265]] 1.0 2bro CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2C3JA 6 270 476.0 DBQ:1271 Type1 Active DFGin 6.95 14.213 BLAminus -126.74, 163.69 80.23, 87.53 -90.31, 22.21 294.83, 82.32 -58.14, -33.43 in-in in 8.796 Saltbr-in 2.899 HRD-in -73.1, -48.96 76.11, 1.81 in-in-in SNCiii in-in ActLoopNT-in 2.882 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.88, 175.78 APE9-dihe-na 109.29, -146.39 APE8-dihe-in -139.98, 118.77 APE8-rot-in 292.58 APE67-dihe-in -63.48, -24.39 -42.88, -48.22 APE12-dist-in 9.223 APE11-dist-in 11.743 APE10-dist-in 6.236 APE9-dist-in 3.31 None None None XRAY 2.1 0.186 0.262 A 297 257 8 0 0 0 [[9, 265]] 1.0 2c3j CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2C3LA 2 273 476.0 IDZ:1274 Type1 Active DFGin 6.887 14.166 BLAminus -131.41, 151.16 78.39, 98.04 -102.86, 15.22 294.33, 84.15 -49.16, -41.07 in-in in 9.023 Saltbr-in 2.703 HRD-in -80.86, -41.66 77.27, -9.64 in-in-in SNCiii in-in ActLoopNT-in 2.76 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.08, -171.58 APE9-dihe-na 93.96, -140.63 APE8-dihe-in -146.55, 106.89 APE8-rot-in 296.71 APE67-dihe-in -64.44, -18.7 -36.5, -53.88 APE12-dist-in 9.208 APE11-dist-in 11.512 APE10-dist-in 6.019 APE9-dist-in 3.39 None None None XRAY 2.35 0.189 0.279 A 297 265 7 0 0 0 [[9, 265]] 1.0 2c3l CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2CGUA 6 271 476.0 3A3:1272 Type1 Active DFGin 6.823 14.1 BLAminus -124.71, 156.71 64.48, 90.01 -96.89, 19.31 292.44, 88.74 -51.64, -28.97 in-in in 8.769 Saltbr-in 2.383 HRD-in -74.29, -41.42 79.85, -2.68 in-in-in SNCiii in-in ActLoopNT-in 3.002 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.8, 178.02 APE9-dihe-na 97.6, -145.39 APE8-dihe-in -133.7, 117.92 APE8-rot-in 294.82 APE67-dihe-in -64.83, -17.81 -46.02, -48.32 APE12-dist-in 9.237 APE11-dist-in 11.48 APE10-dist-in 6.15 APE9-dist-in 3.6 None None None XRAY 2.5 0.185 0.271 A 297 263 3 0 0 0 [[9, 265]] 1.0 2cgu CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2CGVA 6 272 476.0 3B3:1273 Type1 Active DFGin 6.844 14.213 BLAminus -129.68, 147.96 68.93, 97.35 -101.57, 19.74 288.82, 96.28 -56.31, -31.16 in-in in 8.847 Saltbr-in 2.428 HRD-in -68.97, -54.08 89.53, -5.53 in-in-in SNCiii in-in ActLoopNT-in 2.835 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.1, -178.57 APE9-dihe-na 98.55, -155.28 APE8-dihe-in -129.75, 111.18 APE8-rot-in 282.3 APE67-dihe-in -64.98, -23.42 -32.4, -55.02 APE12-dist-in 9.536 APE11-dist-in 11.593 APE10-dist-in 6.218 APE9-dist-in 3.444 None None None XRAY 2.6 0.183 0.256 A 297 264 3 0 0 0 [[9, 265]] 1.0 2cgv CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2CGWA 6 271 476.0 3C3:1272 Type1 Active DFGin 6.888 14.132 BLAminus -126.31, 150.55 70.28, 91.55 -95.72, 25.62 291.49, 82.98 -65.61, -26.92 in-in in 8.914 Saltbr-in 2.721 HRD-in -72.1, -42.26 69.41, 5.33 in-in-in SNCiii in-in ActLoopNT-in 2.924 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.62, 178.07 APE9-dihe-na 112.61, -143.97 APE8-dihe-in -142.62, 117.73 APE8-rot-in 285.52 APE67-dihe-in -65.12, -19.5 -40.76, -49.59 APE12-dist-in 9.127 APE11-dist-in 11.614 APE10-dist-in 6.212 APE9-dist-in 3.397 None None None XRAY 2.2 0.189 0.249 A 297 262 4 0 0 0 [[9, 265]] 1.0 2cgw CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2CGXA 6 273 476.0 3D3:1274 Type1 Active DFGin 6.833 14.117 BLAminus -125.86, 152.33 68.83, 92.31 -96.49, 22.24 295.74, 81.77 -68.33, -25.83 in-in in 8.865 Saltbr-in 2.506 HRD-in -77.3, -42.87 73.93, 3.29 in-in-in SNCiii in-in ActLoopNT-in 2.934 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.75, 179.04 APE9-dihe-na 103.61, -149.01 APE8-dihe-in -138.5, 119.55 APE8-rot-in 290.31 APE67-dihe-in -60.17, -27.97 -48.57, -47.19 APE12-dist-in 9.296 APE11-dist-in 11.659 APE10-dist-in 6.192 APE9-dist-in 3.328 None None None XRAY 2.2 0.191 0.258 A 297 265 3 0 0 0 [[9, 265]] 1.0 2cgx CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
3NLBA 6 271 476.0 5BE:298 Type1 Active DFGin 6.824 14.2 BLAminus -124.55, 157.38 77.01, 93.93 -101.53, 21.95 294.88, 88.17 -62.88, -34.66 in-in in 8.794 Saltbr-in 2.506 HRD-in -79.47, -46.53 76.26, -3.28 in-in-in SNCiii in-in ActLoopNT-in 2.817 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.04, 155.47 APE9-dihe-na 120.15, -160.26 APE8-dihe-in -135.73, 120.95 APE8-rot-in 291.21 APE67-dihe-in -56.59, -27.5 -50.08, -48.2 APE12-dist-in 9.465 APE11-dist-in 11.54 APE10-dist-in 5.744 APE9-dist-in 3.245 None None None XRAY 1.9 0.184 0.241 A 297 261 5 0 0 0 [[9, 265]] 1.0 3nlb CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
5DLSA 6 270 476.0 5CV:301 Type1 Active DFGin 6.776 14.407 BLAminus -127.94, 160.56 79.78, 85.12 -96.72, 25.68 290.3, 82.54 -70.34, -28.9 in-in in 9.245 Saltbr-in 2.667 HRD-in -77.0, -45.98 73.56, 2.81 in-in-in SNCiii in-in ActLoopNT-in 2.948 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.09, 158.49 APE9-dihe-na 127.57, -153.37 APE8-dihe-in -134.23, 121.92 APE8-rot-in 301.31 APE67-dihe-in -59.78, -21.49 -55.94, -43.97 APE12-dist-in 9.434 APE11-dist-in 11.581 APE10-dist-in 5.722 APE9-dist-in 3.526 None None None XRAY 2.15 0.168 0.222 A 297 257 8 0 0 0 [[9, 265]] 1.0 5dls CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7BKNA 7 271 476.0 ADE:301 Type1 Active DFGin 6.715 13.789 BLAminus -123.22, 178.11 54.82, 98.09 -102.01, 23.12 288.04, 98.46 -58.72, -44.48 in-in in 8.457 Saltbr-in 2.721 HRD-in -80.97, -48.58 70.41, 11.52 in-in-in SNCiii in-in ActLoopNT-in 2.978 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.16, 155.63 APE9-dihe-na 150.16, -148.64 APE8-dihe-in -128.29, 117.27 APE8-rot-in 312.17 APE67-dihe-in -60.96, -21.14 -43.64, -55.99 APE12-dist-in 9.397 APE11-dist-in 11.474 APE10-dist-in 6.03 APE9-dist-in 3.709 None None None XRAY 2.74 0.212 0.28 A 297 259 6 0 0 0 [[9, 265]] 1.0 7bkn CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7BKOA 7 271 476.0 TVW:301 Type1 Active DFGin 7.547 14.686 BLAminus -131.7, 142.84 75.6, 98.75 -102.17, 27.33 285.76, 86.92 -59.85, -38.14 in-in in 9.01 Saltbr-in 2.719 HRD-in -80.43, -45.24 72.06, 16.06 in-in-in SNCiii in-in ActLoopNT-in 2.931 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -177.56, 177.47 APE9-dihe-na 109.29, -153.33 APE8-dihe-in -121.47, 124.07 APE8-rot-in 300.96 APE67-dihe-in -54.02, -14.59 -49.3, -62.95 APE12-dist-in 9.072 APE11-dist-in 11.553 APE10-dist-in 6.291 APE9-dist-in 3.27 None None None XRAY 2.3 0.246 0.331 A 297 259 6 0 0 0 [[9, 265]] 1.0 7bko CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4QYEA 3 280 476.0 3DL:301 Type1 Active DFGin 6.914 14.112 BLAminus -124.84, 156.69 77.9, 93.39 -103.1, 23.38 290.26, 80.26 -63.73, -29.53 in-in in 8.942 Saltbr-in 2.583 HRD-in -72.42, -47.96 79.14, 0.2 in-in-in SNCiii in-in ActLoopNT-in 2.861 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.29, 174.85 APE9-dihe-na 114.12, -149.57 APE8-dihe-in -137.26, 119.94 APE8-rot-in 299.74 APE67-dihe-in -63.28, -19.9 -43.96, -48.93 APE12-dist-in 9.079 APE11-dist-in 11.708 APE10-dist-in 6.181 APE9-dist-in 3.258 None None None XRAY 2.05 0.171 0.208 A 298 271 7 0 0 0 [[9, 265]] 1.0 4qye CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4QYFA 3 280 476.0 3DV:301 Type1 Active DFGin 6.897 14.063 BLAminus -128.79, 158.9 75.16, 93.31 -103.23, 30.89 290.8, 79.05 -72.58, -24.18 in-in in 8.932 Saltbr-in 2.669 HRD-in -71.38, -49.09 76.48, 2.12 in-in-in SNCiii in-in ActLoopNT-in 2.919 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -163.94, 176.72 APE9-dihe-na 105.68, -144.7 APE8-dihe-in -142.3, 123.67 APE8-rot-in 303.25 APE67-dihe-in -64.92, -19.69 -49.83, -45.85 APE12-dist-in 8.988 APE11-dist-in 11.703 APE10-dist-in 6.2 APE9-dist-in 3.269 None None None XRAY 2.15 0.171 0.223 A 298 269 7 0 0 0 [[9, 265]] 1.0 4qyf CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4QYGA 3 273 476.0 3DW:301 Type1 Active DFGin 6.729 14.232 BLAminus -130.14, 167.67 66.49, 85.89 -96.57, 24.99 292.46, 83.53 -66.91, -20.27 in-in in 8.613 Saltbr-in 2.684 HRD-in -75.2, -47.38 77.56, 1.13 in-in-in SNCiii in-in ActLoopNT-in 2.916 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.42, 169.22 APE9-dihe-na 118.09, -146.73 APE8-dihe-in -136.23, 118.9 APE8-rot-in 301.78 APE67-dihe-in -58.65, -24.95 -43.65, -51.64 APE12-dist-in 8.923 APE11-dist-in 11.779 APE10-dist-in 6.226 APE9-dist-in 3.41 None None None XRAY 1.75 0.185 0.214 A 298 264 7 0 0 0 [[9, 265]] 1.0 4qyg CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4QYGB 3 273 476.0 3DW:301 Type1 Active DFGin 6.814 14.26 BLAminus -131.28, 167.96 67.6, 84.41 -94.04, 25.62 290.63, 84.63 -68.09, -18.4 in-in in 8.643 Saltbr-in 2.815 HRD-in -74.82, -46.02 77.08, 2.44 in-in-in SNCiii in-in ActLoopNT-in 2.946 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.14, 172.0 APE9-dihe-na 119.92, -148.59 APE8-dihe-in -135.99, 119.53 APE8-rot-in 301.26 APE67-dihe-in -57.64, -21.53 -47.69, -50.26 APE12-dist-in 9.249 APE11-dist-in 11.721 APE10-dist-in 6.149 APE9-dist-in 3.456 None None None XRAY 1.75 0.185 0.214 B 298 264 7 0 0 0 [[9, 265]] 1.0 4qyg CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4QYHA 3 273 476.0 3DX:301 Type1 Active DFGin 6.714 13.841 BLAminus -127.62, 167.13 70.22, 81.93 -93.79, 22.64 293.4, 81.54 -68.79, -21.86 in-in in 8.418 Saltbr-in 3.126 HRD-in -75.71, -43.97 72.44, 2.65 in-in-in SNCiii in-in ActLoopNT-in 2.937 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.3, 173.48 APE9-dihe-na 109.75, -150.14 APE8-dihe-in -135.16, 119.63 APE8-rot-in 304.63 APE67-dihe-in -60.05, -24.72 -49.2, -45.16 APE12-dist-in 9.03 APE11-dist-in 11.673 APE10-dist-in 6.112 APE9-dist-in 3.398 None None None XRAY 1.9 0.199 0.235 A 298 264 7 0 0 0 [[9, 265]] 1.0 4qyh CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4QYHB 3 273 476.0 3DX:301 Type1 Active DFGin 6.879 14.009 BLAminus -124.39, 169.48 67.51, 85.49 -93.96, 24.74 292.25, 85.07 -64.1, -25.79 in-in in 8.511 Saltbr-in 2.792 HRD-in -72.54, -45.81 74.0, 2.82 in-in-in SNCiii in-in ActLoopNT-in 2.878 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.18, 171.25 APE9-dihe-na 115.52, -148.64 APE8-dihe-in -137.75, 119.64 APE8-rot-in 296.85 APE67-dihe-in -60.78, -22.11 -45.63, -50.5 APE12-dist-in 9.125 APE11-dist-in 11.766 APE10-dist-in 6.176 APE9-dist-in 3.458 None None None XRAY 1.9 0.199 0.235 B 298 264 7 0 0 0 [[9, 265]] 1.0 4qyh CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4RVKA 3 273 476.0 3XK:301 Type1 Active DFGin 6.786 14.085 BLAminus -129.79, 164.19 71.3, 92.68 -106.21, 24.95 283.48, 87.3 -69.95, -19.64 in-in in 8.496 Saltbr-in 2.583 HRD-in -71.05, -45.75 75.91, 1.09 in-in-in SNCiii in-in ActLoopNT-in 3.017 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.98, 171.98 APE9-dihe-na 109.08, -154.55 APE8-dihe-in -133.03, 121.44 APE8-rot-in 305.51 APE67-dihe-in -59.83, -19.94 -43.49, -53.85 APE12-dist-in 9.058 APE11-dist-in 11.837 APE10-dist-in 6.179 APE9-dist-in 3.177 None None None XRAY 1.85 0.26 0.299 A 298 264 7 0 0 0 [[9, 265]] 1.0 4rvk CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4RVLA 3 273 476.0 3XL:301 Type1 Active DFGin 6.89 14.115 BLAminus -127.93, 163.2 71.68, 92.52 -100.89, 24.56 288.93, 80.66 -66.04, -26.13 in-in in 8.546 Saltbr-in 2.691 HRD-in -73.58, -46.56 74.64, 2.34 in-in-in SNCiii in-in ActLoopNT-in 2.899 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.27, 175.0 APE9-dihe-na 109.81, -150.01 APE8-dihe-in -139.94, 120.27 APE8-rot-in 300.49 APE67-dihe-in -61.11, -23.55 -46.48, -50.16 APE12-dist-in 9.112 APE11-dist-in 11.806 APE10-dist-in 6.191 APE9-dist-in 3.225 None None None XRAY 1.85 0.19 0.216 A 298 258 13 0 0 0 [[9, 265]] 1.0 4rvl CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4RVMA 3 273 476.0 3X7:301 Type1 Active DFGin 6.862 14.038 BLAminus -123.09, 161.86 72.52, 87.28 -98.9, 25.75 290.38, 81.52 -65.59, -25.28 in-in in 8.499 Saltbr-in 2.659 HRD-in -75.9, -43.39 74.19, 2.07 in-in-in SNCiii in-in ActLoopNT-in 2.923 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -149.76, 173.82 APE9-dihe-na 114.14, -153.45 APE8-dihe-in -138.11, 123.56 APE8-rot-in 300.31 APE67-dihe-in -62.25, -23.64 -48.14, -48.07 APE12-dist-in 9.028 APE11-dist-in 11.724 APE10-dist-in 6.066 APE9-dist-in 3.304 None None None XRAY 1.86 0.203 0.242 A 298 264 7 0 0 0 [[9, 265]] 1.0 4rvm CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7AKOA 2 271 476.0 STU:60301 Type1 Active DFGin 7.258 14.346 BLAminus -129.99, 164.38 63.12, 90.57 -95.99, 30.1 286.66, 77.28 -66.31, -26.96 in-in in 8.834 Saltbr-in 2.687 HRD-in -79.3, -45.9 76.54, 2.66 in-in-in SNCiii in-in ActLoopNT-in 2.999 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -151.15, 172.04 APE9-dihe-na 107.34, -156.22 APE8-dihe-in -136.58, 123.75 APE8-rot-in 305.71 APE67-dihe-in -59.04, -20.83 -49.6, -50.22 APE12-dist-in 8.951 APE11-dist-in 11.921 APE10-dist-in 6.385 APE9-dist-in 3.572 D10R None None XRAY 1.8 0.192 0.235 A 300 270 0 0 0 0 [[9, 265]] 1.0 7ako CAMK_CHEK1_HUMAN CAMK 3.4e-71 245.5 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7AKOB 2 271 476.0 STU:60301 Type1 Active DFGin 7.037 14.527 BLAminus -133.06, 166.86 60.65, 91.44 -101.1, 26.21 287.91, 78.35 -62.72, -24.94 in-in in 9.183 Saltbr-in 3.404 HRD-in -77.35, -44.25 76.09, 6.63 in-in-in SNCiii in-in ActLoopNT-in 3.039 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -146.79, 168.24 APE9-dihe-na 123.14, -149.89 APE8-dihe-in -132.89, 126.1 APE8-rot-in 304.27 APE67-dihe-in -62.82, -10.87 -52.63, -48.98 APE12-dist-in 8.63 APE11-dist-in 11.884 APE10-dist-in 6.247 APE9-dist-in 3.495 D10R None None XRAY 1.8 0.192 0.235 B 300 270 0 0 0 0 [[9, 265]] 1.0 7ako CAMK_CHEK1_HUMAN CAMK 3.4e-71 245.5 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2HOGA 2 280 476.0 710:324 Type1 Active DFGin 6.918 14.348 BLAminus -132.2, 167.83 69.16, 94.58 -104.9, 28.28 291.65, 77.59 -68.3, -20.83 in-in in 8.924 Saltbr-in 2.865 HRD-in -73.55, -46.39 73.44, 0.35 in-in-in SNCiii in-in ActLoopNT-in 3.026 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.82, 159.6 APE9-dihe-na 116.01, -154.6 APE8-dihe-in -136.97, 116.06 APE8-rot-in 302.9 APE67-dihe-in -59.7, -25.14 -31.53, -54.03 APE12-dist-in 9.189 APE11-dist-in 11.437 APE10-dist-in 5.925 APE9-dist-in 3.214 None None None XRAY 1.9 0.204 0.236 A 322 272 7 0 0 0 [[9, 265]] 1.0 2hog CAMK_CHEK1_HUMAN CAMK 3.8e-71 245.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2HXLA 2 276 476.0 422:324 Type1 Active DFGin 6.846 14.071 BLAminus -130.75, 166.76 70.33, 92.55 -103.77, 30.08 290.87, 84.03 -71.02, -25.09 in-in in 8.678 Saltbr-in 2.947 HRD-in -72.98, -44.67 70.07, 1.52 in-in-in SNCiii in-in ActLoopNT-in 2.912 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.32, 153.75 APE9-dihe-na 120.45, -160.19 APE8-dihe-in -131.74, 120.76 APE8-rot-in 304.55 APE67-dihe-in -61.62, -21.58 -33.66, -54.8 APE12-dist-in 9.16 APE11-dist-in 11.242 APE10-dist-in 5.758 APE9-dist-in 3.296 None None None XRAY 1.8 0.24 0.27 A 322 272 3 0 0 0 [[9, 265]] 1.0 2hxl CAMK_CHEK1_HUMAN CAMK 3.8e-71 245.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2QHMA 2 280 476.0 7CS:500 Type1 Active DFGin 6.772 14.08 BLAminus -128.04, 164.43 76.84, 101.69 -108.83, 21.45 292.71, 82.54 -63.16, -31.58 in-in in 8.975 Saltbr-in 3.022 HRD-in -76.01, -44.64 71.83, -0.16 in-in-in SNCiii in-in ActLoopNT-in 2.887 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.23, 170.83 APE9-dihe-na 117.51, -152.64 APE8-dihe-in -136.18, 123.8 APE8-rot-in 296.25 APE67-dihe-in -58.13, -21.13 -38.91, -55.77 APE12-dist-in 9.195 APE11-dist-in 11.636 APE10-dist-in 6.134 APE9-dist-in 3.16 None None None XRAY 2.0 0.195 0.237 A 323 268 11 0 0 0 [[9, 265]] 1.0 2qhm CAMK_CHEK1_HUMAN CAMK 3.9e-71 245.3 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2QHNA 2 280 476.0 582:500 Type1 Active DFGin 6.88 14.133 BLAminus -126.49, 161.83 70.32, 93.37 -99.87, 25.92 292.06, 80.64 -63.7, -34.99 in-in in 8.792 Saltbr-in 2.746 HRD-in -76.39, -44.4 73.61, -2.54 in-in-in SNCiii in-in ActLoopNT-in 2.92 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -140.44, 160.33 APE9-dihe-na 118.4, -157.67 APE8-dihe-in -138.42, 120.63 APE8-rot-in 297.79 APE67-dihe-in -60.96, -22.13 -36.11, -57.97 APE12-dist-in 9.21 APE11-dist-in 11.621 APE10-dist-in 5.881 APE9-dist-in 3.191 None None None XRAY 1.7 0.203 0.23 A 323 268 11 0 0 0 [[9, 265]] 1.0 2qhn CAMK_CHEK1_HUMAN CAMK 3.9e-71 245.3 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2R0UA 2 280 476.0 M54:324 Type1 Active DFGin 6.879 14.783 BLAminus -130.98, 175.0 63.44, 83.35 -98.83, 22.14 288.69, 85.22 -65.61, -26.86 in-in in 8.562 Saltbr-in 2.792 HRD-in -79.55, -46.26 72.28, 2.27 in-in-in SNCiii in-in ActLoopNT-in 2.924 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.26, 151.84 APE9-dihe-na 117.81, -152.92 APE8-dihe-in -133.39, 116.35 APE8-rot-in 302.77 APE67-dihe-in -61.49, -22.1 -35.67, -54.4 APE12-dist-in 9.247 APE11-dist-in 11.356 APE10-dist-in 6.137 APE9-dist-in 3.226 None None None XRAY 1.9 0.197 0.218 A 323 269 10 0 0 0 [[9, 265]] 1.0 2r0u CAMK_CHEK1_HUMAN CAMK 3.9e-71 245.3 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
3TKHA 2 280 476.0 07S:325 Type1 Active DFGin 7.036 14.129 BLAminus -125.51, 167.65 65.08, 90.5 -95.72, 21.17 290.82, 87.11 -61.09, -34.24 in-in in 8.501 Saltbr-in 2.814 HRD-in -73.35, -45.96 71.88, 1.74 in-in-in SNCiii in-in ActLoopNT-in 2.877 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.84, 155.22 APE9-dihe-na 115.35, -158.04 APE8-dihe-in -134.64, 120.26 APE8-rot-in 299.43 APE67-dihe-in -61.5, -21.36 -39.52, -53.35 APE12-dist-in 9.09 APE11-dist-in 11.256 APE10-dist-in 5.784 APE9-dist-in 3.223 None None None XRAY 1.79 0.184 0.201 A 323 269 10 0 0 0 [[9, 265]] 1.0 3tkh CAMK_CHEK1_HUMAN CAMK 3.9e-71 245.3 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
3TKIA 2 280 476.0 S25:325 Type1 Active DFGin 7.066 14.047 BLAminus -128.14, 167.81 66.79, 92.13 -100.38, 25.08 290.04, 84.3 -65.02, -26.24 in-in in 8.512 Saltbr-in 2.702 HRD-in -75.61, -43.71 71.45, -3.34 in-in-in SNCiii in-in ActLoopNT-in 2.891 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.41, 152.37 APE9-dihe-na 119.25, -155.65 APE8-dihe-in -135.42, 118.76 APE8-rot-in 302.07 APE67-dihe-in -61.44, -22.09 -36.74, -54.05 APE12-dist-in 9.235 APE11-dist-in 11.298 APE10-dist-in 5.79 APE9-dist-in 3.237 None None None XRAY 1.6 0.188 0.212 A 323 272 7 0 0 0 [[9, 265]] 1.0 3tki CAMK_CHEK1_HUMAN CAMK 3.9e-71 245.3 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
5OQ5A 3 270 476.0 4K4:301 Type1 Active DFGin 7.212 14.393 BLAminus -137.57, 166.94 72.85, 88.19 -97.66, 22.2 287.41, 72.48 -72.17, -15.94 in-in in 9.401 Saltbr-in 2.848 HRD-in -76.62, -42.87 75.17, -5.02 in-in-in SNCiii in-in ActLoopNT-in 2.988 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -166.87, 165.21 APE9-dihe-na 121.43, -145.46 APE8-dihe-in -135.47, 115.76 APE8-rot-in 308.05 APE67-dihe-in -59.16, -21.13 -45.59, -50.3 APE12-dist-in 9.114 APE11-dist-in 11.477 APE10-dist-in 6.308 APE9-dist-in 3.513 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A None None XRAY 1.4 0.17 0.185 A 297 265 3 0 0 0 [[9, 265]] 1.0 5oq5 CAMK_CHEK1_HUMAN CAMK 1e-70 243.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
5OQ7A 8 271 476.0 A0Q:301 Type1 Active DFGin 7.123 14.284 BLAminus -115.9, 149.42 83.67, 113.44 -120.56, 20.12 282.1, 87.3 -60.35, -30.28 in-in in 9.129 Saltbr-in 2.185 HRD-in -72.95, -46.31 71.63, 7.81 in-in-in SNCiii in-in ActLoopNT-in 2.954 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.79, 177.88 APE9-dihe-na 107.24, -147.89 APE8-dihe-in -133.83, 123.88 APE8-rot-in 304.96 APE67-dihe-in -60.86, -17.32 -51.61, -47.12 APE12-dist-in 9.968 APE11-dist-in 11.63 APE10-dist-in 6.087 APE9-dist-in 3.712 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A None None XRAY 2.1 0.259 0.324 A 297 259 5 0 0 0 [[9, 265]] 1.0 5oq7 CAMK_CHEK1_HUMAN CAMK 1e-70 243.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
5OQ7B 8 270 476.0 A0Q:301 Type1 Active DFGin 7.007 13.668 BLAminus -123.41, 144.51 76.15, 112.19 -116.09, 30.53 288.02, 74.92 -74.13, -26.43 in-in in 8.562 Saltbr-in 3.412 HRD-in -68.73, -47.06 88.33, -2.49 in-in-in SNCiii in-in ActLoopNT-in 2.963 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.0, 169.92 APE9-dihe-na 126.71, -154.19 APE8-dihe-in -137.81, 141.49 APE8-rot-in 282.73 APE67-dihe-in -51.67, -38.82 -61.07, -53.98 APE12-dist-in 9.025 APE11-dist-in 11.512 APE10-dist-in 6.116 APE9-dist-in 3.699 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A None None XRAY 2.1 0.259 0.324 B 297 256 7 0 0 0 [[9, 265]] 1.0 5oq7 CAMK_CHEK1_HUMAN CAMK 1e-70 243.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FSUA 4 271 476.0 HK5:301 Type1 Active DFGin 6.925 14.242 BLAminus -130.65, 164.24 65.93, 99.19 -104.79, 24.05 288.61, 85.53 -67.15, -26.86 in-in in 8.688 Saltbr-in 2.717 HRD-in -71.9, -47.68 71.19, 6.28 in-in-in SNCiii in-in ActLoopNT-in 2.993 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.25, 165.58 APE9-dihe-na 117.09, -150.06 APE8-dihe-in -133.92, 119.44 APE8-rot-in 307.97 APE67-dihe-in -62.25, -20.9 -38.55, -52.24 APE12-dist-in 9.127 APE11-dist-in 11.471 APE10-dist-in 6.003 APE9-dist-in 3.306 None None None XRAY 2.1 0.173 0.181 A 279 260 8 0 0 0 [[9, 265]] 1.0 4fsu CAMK_CHEK1_HUMAN CAMK 7.2e-71 244.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
5OQ6A 5 270 476.0 4K4:301 Type1 Active DFGin 6.952 13.956 BLAminus -116.27, 166.19 73.35, 97.82 -108.78, 21.61 291.33, 79.85 -70.94, -23.48 in-in in 9.39 Saltbr-in 2.768 HRD-in -76.04, -43.87 68.12, 2.56 in-in-in SNCiii in-in ActLoopNT-in 2.887 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -148.4, 175.01 APE9-dihe-na 115.83, -158.06 APE8-dihe-in -132.34, 123.75 APE8-rot-in 301.05 APE67-dihe-in -65.69, -17.68 -49.58, -46.31 APE12-dist-in 9.232 APE11-dist-in 11.239 APE10-dist-in 5.945 APE9-dist-in 3.435 A19S,Y20F,N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.95 0.16 0.192 A 297 257 9 0 0 0 [[9, 265]] 1.0 5oq6 CAMK_CHEK1_HUMAN CAMK 1.8e-69 239.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
5OQ8A 4 270 476.0 A0Q:301 Type1 Active DFGin 6.976 13.708 BLAminus -114.65, 171.07 70.74, 94.75 -100.36, 20.44 291.87, 83.91 -68.92, -28.4 in-in in 8.527 Saltbr-in 3.218 HRD-in -74.36, -44.04 71.63, 3.1 in-in-in SNCiii in-in ActLoopNT-in 2.982 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.21, 175.51 APE9-dihe-na 117.46, -150.37 APE8-dihe-in -131.31, 125.96 APE8-rot-in 300.85 APE67-dihe-in -65.06, -17.09 -46.84, -53.17 APE12-dist-in 8.854 APE11-dist-in 11.643 APE10-dist-in 6.306 APE9-dist-in 3.561 A19S,Y20F,N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.0 0.167 0.2 A 297 261 6 0 0 0 [[9, 265]] 1.0 5oq8 CAMK_CHEK1_HUMAN CAMK 1.8e-69 239.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
9CE4A 4 271 476.0 A1AV4:301 Type1 Active DFGin 7.2 13.454 BLAminus -119.78, 162.88 71.89, 104.85 -111.17, 21.45 289.63, 81.1 -64.05, -28.25 in-in in 9.118 Saltbr-in 3.069 HRD-in -74.27, -45.02 73.63, 3.4 in-in-in SNCiii in-in ActLoopNT-in 2.915 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -166.42, 168.37 APE9-dihe-na 118.29, -153.71 APE8-dihe-in -135.96, 121.9 APE8-rot-in 300.47 APE67-dihe-in -61.86, -20.64 -47.17, -48.09 APE12-dist-in 8.867 APE11-dist-in 11.566 APE10-dist-in 6.067 APE9-dist-in 3.326 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.31 0.184 0.221 A 268 258 10 0 0 0 [[9, 265]] 1.0 9ce4 CAMK_CHEK1_HUMAN CAMK 3.3e-69 239.0 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
5OOTA 4 270 476.0 4K4:301 Type1 Active DFGin 6.886 13.873 BLAminus -123.71, 160.5 78.56, 100.42 -111.81, 22.75 292.67, 78.9 -75.98, -17.85 in-in in 9.323 Saltbr-in 2.824 HRD-in -78.85, -47.77 75.66, -4.37 in-in-in SNCiii in-in ActLoopNT-in 2.876 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.46, 155.57 APE9-dihe-na 122.12, -167.22 APE8-dihe-in -131.08, 125.87 APE8-rot-in 298.0 APE67-dihe-in -65.3, -21.81 -53.02, -44.26 APE12-dist-in 9.155 APE11-dist-in 11.18 APE10-dist-in 5.735 APE9-dist-in 3.446 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.1 0.178 0.224 A 297 260 7 0 0 0 [[9, 265]] 1.0 5oot CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
5OP2A 4 271 476.0 A0Q:301 Type1 Active DFGin 6.975 13.81 BLAminus -113.46, 163.41 77.81, 100.2 -106.41, 21.36 291.61, 81.69 -69.8, -25.56 in-in in 8.491 Saltbr-in 3.191 HRD-in -77.36, -46.21 76.3, -1.69 in-in-in SNCiii in-in ActLoopNT-in 2.915 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.61, 173.53 APE9-dihe-na 118.89, -148.19 APE8-dihe-in -135.3, 122.77 APE8-rot-in 300.97 APE67-dihe-in -69.82, -15.47 -49.44, -44.8 APE12-dist-in 9.453 APE11-dist-in 11.716 APE10-dist-in 6.284 APE9-dist-in 3.551 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.9 0.161 0.2 A 297 263 5 0 0 0 [[9, 265]] 1.0 5op2 CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
5OP4A 3 270 476.0 A0T:301 Type1 Active DFGin 6.958 13.676 BLAminus -120.25, 163.52 72.52, 97.08 -105.73, 22.62 289.58, 82.01 -73.58, -24.61 in-in in 9.18 Saltbr-in 2.607 HRD-in -76.46, -44.61 73.33, 0.98 in-in-in SNCiii in-in ActLoopNT-in 2.908 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.0, 176.3 APE9-dihe-na 113.44, -150.07 APE8-dihe-in -134.9, 124.12 APE8-rot-in 296.27 APE67-dihe-in -63.53, -18.17 -48.69, -47.33 APE12-dist-in 9.066 APE11-dist-in 11.571 APE10-dist-in 6.194 APE9-dist-in 3.507 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.0 0.169 0.205 A 297 259 9 0 0 0 [[9, 265]] 1.0 5op4 CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
5OP5A 4 270 476.0 3FE:301 Type1 Active DFGin 7.143 13.656 BLAminus -111.04, 162.46 74.82, 99.79 -113.07, 20.16 292.98, 78.11 -70.13, -26.75 in-in in 9.394 Saltbr-in 2.894 HRD-in -76.35, -46.93 73.16, 0.06 in-in-in SNCiii in-in ActLoopNT-in 2.881 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.71, 173.57 APE9-dihe-na 115.19, -153.36 APE8-dihe-in -133.92, 122.39 APE8-rot-in 297.32 APE67-dihe-in -67.39, -15.82 -48.27, -44.76 APE12-dist-in 8.865 APE11-dist-in 11.706 APE10-dist-in 6.215 APE9-dist-in 3.408 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.9 0.162 0.206 A 297 259 8 0 0 0 [[9, 265]] 1.0 5op5 CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
5OP7A 4 270 476.0 A1K:301 Type1 Active DFGin 7.07 13.523 BLAminus -119.38, 164.65 74.16, 96.12 -105.6, 23.88 293.2, 80.09 -71.41, -20.33 in-in in 9.375 Saltbr-in 3.062 HRD-in -82.06, -43.11 72.25, 1.02 in-in-in SNCiii in-in ActLoopNT-in 2.933 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.04, 177.16 APE9-dihe-na 111.37, -152.73 APE8-dihe-in -135.08, 120.27 APE8-rot-in 299.86 APE67-dihe-in -68.14, -17.85 -45.44, -46.06 APE12-dist-in 9.049 APE11-dist-in 11.652 APE10-dist-in 6.145 APE9-dist-in 3.4 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.8 0.168 0.215 A 297 261 6 0 0 0 [[9, 265]] 1.0 5op7 CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
5OPBA 5 271 476.0 A1N:301 Type1 Active DFGin 6.928 13.631 BLAminus -127.5, 170.57 73.1, 96.55 -104.05, 19.63 293.23, 83.02 -63.66, -29.12 in-in in 8.49 Saltbr-in 3.041 HRD-in -78.76, -48.56 80.79, -4.96 in-in-in SNCiii in-in ActLoopNT-in 2.957 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.16, 173.26 APE9-dihe-na 113.85, -143.9 APE8-dihe-in -134.72, 122.47 APE8-rot-in 308.74 APE67-dihe-in -59.7, -23.28 -50.86, -47.55 APE12-dist-in 9.376 APE11-dist-in 11.665 APE10-dist-in 6.233 APE9-dist-in 3.579 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.55 0.165 0.189 A 297 262 5 0 0 0 [[9, 265]] 1.0 5opb CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
5OPRA 4 270 476.0 A3E:301 Type1 Active DFGin 6.957 13.557 BLAminus -118.63, 168.17 71.59, 95.55 -107.46, 21.7 291.34, 81.1 -71.92, -24.17 in-in in 9.22 Saltbr-in 2.75 HRD-in -75.64, -44.16 68.61, -1.61 in-in-in SNCiii in-in ActLoopNT-in 2.911 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.69, 179.14 APE9-dihe-na 109.46, -150.3 APE8-dihe-in -134.98, 121.9 APE8-rot-in 296.29 APE67-dihe-in -64.62, -18.13 -48.76, -45.83 APE12-dist-in 8.759 APE11-dist-in 11.804 APE10-dist-in 6.28 APE9-dist-in 3.415 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.95 0.166 0.206 A 297 258 9 0 0 0 [[9, 265]] 1.0 5opr CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
5OPSA 3 270 476.0 A3Q:301 Type1 Active DFGin 6.979 13.573 BLAminus -124.54, 166.57 74.59, 94.68 -104.11, 23.06 293.13, 78.93 -70.21, -22.8 in-in in 9.235 Saltbr-in 2.889 HRD-in -76.05, -44.37 71.1, -0.07 in-in-in SNCiii in-in ActLoopNT-in 2.876 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.5, 174.02 APE9-dihe-na 119.54, -152.79 APE8-dihe-in -133.46, 124.35 APE8-rot-in 295.76 APE67-dihe-in -58.43, -25.41 -48.38, -48.15 APE12-dist-in 9.124 APE11-dist-in 11.654 APE10-dist-in 6.24 APE9-dist-in 3.516 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.0 0.163 0.202 A 297 258 10 0 0 0 [[9, 265]] 1.0 5ops CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
5OPUA 3 271 476.0 A3K:301 Type1 Active DFGin 7.057 13.473 BLAminus -118.42, 161.45 74.22, 104.07 -109.02, 22.53 294.09, 83.39 -63.01, -33.06 in-in in 9.238 Saltbr-in 2.676 HRD-in -82.38, -42.44 75.35, -1.05 in-in-in SNCiii in-in ActLoopNT-in 2.919 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.28, 171.71 APE9-dihe-na 121.99, -160.54 APE8-dihe-in -131.47, 121.55 APE8-rot-in 303.24 APE67-dihe-in -61.44, -19.07 -47.23, -48.74 APE12-dist-in 9.143 APE11-dist-in 11.703 APE10-dist-in 6.177 APE9-dist-in 3.481 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.55 0.172 0.206 A 297 261 8 0 0 0 [[9, 265]] 1.0 5opu CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
5OPVA 3 270 476.0 A3H:301 Type1 Active DFGin 6.96 13.606 BLAminus -121.69, 163.58 77.05, 97.9 -108.91, 21.22 289.09, 85.65 -63.92, -35.33 in-in in 9.186 Saltbr-in 2.453 HRD-in -77.36, -47.2 74.21, -3.64 in-in-in SNCiii in-in ActLoopNT-in 2.856 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.2, 172.7 APE9-dihe-na 122.38, -151.0 APE8-dihe-in -136.47, 125.7 APE8-rot-in 297.44 APE67-dihe-in -66.18, -19.24 -51.65, -45.72 APE12-dist-in 9.25 APE11-dist-in 11.717 APE10-dist-in 6.255 APE9-dist-in 3.504 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.9 0.166 0.204 A 297 261 7 0 0 0 [[9, 265]] 1.0 5opv CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7BJDA 3 270 476.0 TVT:301 Type1 Active DFGin 7.084 13.659 BLAminus -125.76, 163.02 71.86, 96.41 -103.13, 21.61 289.17, 82.5 -71.88, -23.03 in-in in 8.887 Saltbr-in 2.9 HRD-in -76.23, -50.44 76.99, 0.19 in-in-in SNCiii in-in ActLoopNT-in 2.882 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.69, 177.15 APE9-dihe-na 113.59, -153.08 APE8-dihe-in -130.22, 124.06 APE8-rot-in 306.43 APE67-dihe-in -62.37, -19.5 -51.28, -48.54 APE12-dist-in 9.017 APE11-dist-in 11.599 APE10-dist-in 6.089 APE9-dist-in 3.331 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.0 0.164 0.197 A 297 263 5 0 0 0 [[9, 265]] 1.0 7bjd CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7BJEA 4 270 476.0 ADE:301 Type1 Active DFGin 7.057 13.586 BLAminus -121.21, 160.63 79.82, 94.56 -105.52, 22.95 292.15, 82.58 -70.69, -20.75 in-in in 9.168 Saltbr-in 2.978 HRD-in -77.37, -47.27 75.12, 0.05 in-in-in SNCiii in-in ActLoopNT-in 2.832 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.98, 175.66 APE9-dihe-na 111.76, -150.84 APE8-dihe-in -133.41, 122.32 APE8-rot-in 300.48 APE67-dihe-in -64.02, -19.73 -50.61, -46.69 APE12-dist-in 8.933 APE11-dist-in 11.738 APE10-dist-in 6.194 APE9-dist-in 3.38 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.8 0.173 0.199 A 297 259 8 0 0 0 [[9, 265]] 1.0 7bje CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7BJHA 3 270 476.0 42C:301 Type1 Active DFGin 7.039 13.667 BLAminus -116.34, 165.35 72.91, 98.36 -107.78, 21.47 288.28, 79.82 -69.94, -23.59 in-in in 9.239 Saltbr-in 2.782 HRD-in -77.33, -48.21 78.81, 0.79 in-in-in SNCiii in-in ActLoopNT-in 2.909 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.22, 175.12 APE9-dihe-na 118.78, -150.24 APE8-dihe-in -133.09, 120.06 APE8-rot-in 303.88 APE67-dihe-in -64.34, -19.53 -50.28, -45.23 APE12-dist-in 9.002 APE11-dist-in 11.736 APE10-dist-in 6.218 APE9-dist-in 3.433 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.8 0.173 0.201 A 297 260 8 0 0 0 [[9, 265]] 1.0 7bjh CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7BJJA 3 270 476.0 TVW:301 Type1 Active DFGin 7.065 13.659 BLAminus -124.47, 161.87 75.65, 95.41 -106.95, 21.08 288.5, 86.21 -71.04, -20.76 in-in in 9.294 Saltbr-in 2.932 HRD-in -76.46, -47.86 74.54, -0.21 in-in-in SNCiii in-in ActLoopNT-in 2.901 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.52, 179.25 APE9-dihe-na 107.66, -150.8 APE8-dihe-in -135.65, 121.21 APE8-rot-in 299.15 APE67-dihe-in -63.43, -20.51 -51.77, -45.13 APE12-dist-in 9.114 APE11-dist-in 11.71 APE10-dist-in 6.256 APE9-dist-in 3.337 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.8 0.173 0.199 A 297 260 8 0 0 0 [[9, 265]] 1.0 7bjj CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7BJOA 5 271 476.0 TWK:301 Type1 Active DFGin 7.063 13.645 BLAminus -119.72, 158.64 80.12, 94.27 -104.94, 21.07 290.11, 79.57 -69.06, -22.79 in-in in 9.503 Saltbr-in 2.64 HRD-in -81.64, -47.92 81.07, 0.87 in-in-in SNCiii in-in ActLoopNT-in 2.951 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.78, 172.47 APE9-dihe-na 110.38, -152.68 APE8-dihe-in -132.39, 122.75 APE8-rot-in 300.0 APE67-dihe-in -67.01, -18.62 -51.35, -43.85 APE12-dist-in 8.924 APE11-dist-in 11.792 APE10-dist-in 6.242 APE9-dist-in 3.469 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.3 0.165 0.207 A 297 257 10 0 0 0 [[9, 265]] 1.0 7bjo CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7BJRA 5 270 476.0 TWH:301 Type1 Active DFGin 6.963 13.498 BLAminus -124.23, 160.3 73.7, 98.78 -105.4, 21.99 292.68, 81.21 -49.01, -45.76 in-in in 9.066 Saltbr-in 3.046 HRD-in -75.2, -49.25 73.18, 6.16 in-in-in SNCiii in-in ActLoopNT-in 2.859 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.32, 175.86 APE9-dihe-na 108.36, -150.65 APE8-dihe-in -133.02, 123.34 APE8-rot-in 301.05 APE67-dihe-in -62.65, -20.92 -50.03, -48.58 APE12-dist-in 8.838 APE11-dist-in 11.799 APE10-dist-in 6.257 APE9-dist-in 3.4 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.9 0.17 0.192 A 297 257 9 0 0 0 [[9, 265]] 1.0 7bjr CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7BJXA 8 270 476.0 U0Q:301 Type1 Active DFGin 6.968 14.013 BLAminus -119.16, 168.61 74.53, 87.65 -98.83, 25.0 288.63, 92.62 -71.16, -25.36 in-in in 8.842 Saltbr-in 2.732 HRD-in -66.51, -58.83 81.76, -3.62 in-in-in SNCiii in-in ActLoopNT-in 2.899 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -162.31, 174.42 APE9-dihe-na 110.98, -158.13 APE8-dihe-in -122.51, 124.96 APE8-rot-in 305.1 APE67-dihe-in -66.42, -15.88 -52.33, -43.64 APE12-dist-in 8.815 APE11-dist-in 11.547 APE10-dist-in 6.103 APE9-dist-in 3.512 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.4 0.204 0.26 A 297 255 8 0 0 0 [[9, 265]] 1.0 7bjx CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7BJXB 8 270 476.0 U0Q:301 Type1 Active DFGin 7.008 13.879 BLAminus -129.53, 170.8 70.69, 86.19 -101.81, 34.09 285.2, 93.96 -77.01, -26.91 in-in in 9.087 Saltbr-in 3.266 HRD-in -62.72, -54.04 75.21, -2.93 in-in-in SNCiii in-in ActLoopNT-in 2.904 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.42, 172.2 APE9-dihe-na 111.07, -153.42 APE8-dihe-in -130.98, 128.58 APE8-rot-in 299.81 APE67-dihe-in -59.32, -22.77 -56.3, -49.67 APE12-dist-in 8.587 APE11-dist-in 11.566 APE10-dist-in 6.022 APE9-dist-in 3.621 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.4 0.204 0.26 B 297 252 11 0 0 0 [[9, 265]] 1.0 7bjx CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7BK1A 8 271 476.0 U0N:301 Type1 Active DFGin 6.8 13.783 BLAminus -121.8, 173.16 69.15, 89.56 -98.11, 18.64 290.94, 87.09 -66.87, -20.33 in-in in 8.546 Saltbr-in 3.38 HRD-in -76.9, -49.43 72.98, 3.48 in-in-in SNCiii in-in ActLoopNT-in 2.928 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.0, 174.77 APE9-dihe-na 112.34, -139.81 APE8-dihe-in -141.03, 122.43 APE8-rot-in 302.84 APE67-dihe-in -62.03, -22.5 -53.49, -49.69 APE12-dist-in 9.205 APE11-dist-in 11.678 APE10-dist-in 6.206 APE9-dist-in 3.494 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.0 0.192 0.235 A 297 257 7 0 0 0 [[9, 265]] 1.0 7bk1 CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7BK2A 5 271 476.0 U0K:301 Type1 Active DFGin 6.89 13.774 BLAminus -124.82, 175.43 66.05, 93.67 -102.6, 23.32 290.62, 82.89 -71.81, -20.62 in-in in 8.786 Saltbr-in 3.063 HRD-in -73.35, -50.82 74.75, 4.72 in-in-in SNCiii in-in ActLoopNT-in 2.982 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.63, 173.84 APE9-dihe-na 113.99, -151.94 APE8-dihe-in -129.35, 119.79 APE8-rot-in 306.75 APE67-dihe-in -61.35, -18.19 -45.89, -53.1 APE12-dist-in 9.199 APE11-dist-in 11.66 APE10-dist-in 6.227 APE9-dist-in 3.529 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.0 0.16 0.197 A 297 261 6 0 0 0 [[9, 265]] 1.0 7bk2 CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7BK3A 5 271 476.0 U0T:301 Type1 Active DFGin 6.904 13.759 BLAminus -123.18, 173.88 64.54, 96.63 -101.84, 19.24 289.62, 86.83 -69.92, -22.88 in-in in 8.744 Saltbr-in 3.063 HRD-in -77.61, -49.43 74.89, 4.0 in-in-in SNCiii in-in ActLoopNT-in 2.981 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.55, 173.32 APE9-dihe-na 112.42, -148.12 APE8-dihe-in -134.42, 118.62 APE8-rot-in 305.11 APE67-dihe-in -61.9, -17.64 -49.91, -49.05 APE12-dist-in 9.145 APE11-dist-in 11.641 APE10-dist-in 6.172 APE9-dist-in 3.561 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.0 0.173 0.225 A 297 261 6 0 0 0 [[9, 265]] 1.0 7bk3 CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7MCKA 4 271 476.0 YXD:301 Type1 Active DFGin 7.091 13.493 BLAminus -116.14, 168.88 70.05, 99.13 -109.49, 22.2 291.12, 80.38 -65.63, -23.95 in-in in 9.043 Saltbr-in 2.85 HRD-in -72.23, -49.13 74.37, 1.18 in-in-in SNCiii in-in ActLoopNT-in 2.911 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.37, 168.45 APE9-dihe-na 112.73, -156.62 APE8-dihe-in -133.72, 119.69 APE8-rot-in 302.23 APE67-dihe-in -64.04, -21.06 -43.31, -48.42 APE12-dist-in 8.853 APE11-dist-in 11.364 APE10-dist-in 5.852 APE9-dist-in 3.274 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.65 0.194 0.225 A 297 263 5 0 0 0 [[9, 265]] 1.0 7mck CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7SUFA 3 271 476.0 BVI:301 Type1 Active DFGin 7.129 13.724 BLAminus -103.46, 166.86 70.95, 94.53 -102.33, 19.69 289.72, 86.68 -81.72, -14.95 in-in in 8.962 Saltbr-in 2.915 HRD-in -77.79, -44.59 69.25, -2.58 in-in-in SNCiii in-in ActLoopNT-in 2.862 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.93, 167.68 APE9-dihe-na 123.94, -141.99 APE8-dihe-in -136.26, 119.39 APE8-rot-in 302.86 APE67-dihe-in -66.27, -16.33 -43.58, -49.38 APE12-dist-in 8.865 APE11-dist-in 11.886 APE10-dist-in 6.357 APE9-dist-in 3.433 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.48 0.219 0.254 A 297 262 7 0 0 0 [[9, 265]] 1.0 7suf CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7SUGA 3 271 476.0 BWI:301 Type1 Active DFGin 7.129 13.724 BLAminus -103.46, 166.86 70.95, 94.53 -102.33, 19.69 289.72, 86.68 -81.72, -14.95 in-in in 8.962 Saltbr-in 2.915 HRD-in -77.79, -44.59 69.25, -2.58 in-in-in SNCiii in-in ActLoopNT-in 2.862 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.93, 167.68 APE9-dihe-na 123.94, -141.99 APE8-dihe-in -136.26, 119.39 APE8-rot-in 302.86 APE67-dihe-in -66.27, -16.33 -43.58, -49.38 APE12-dist-in 8.865 APE11-dist-in 11.886 APE10-dist-in 6.357 APE9-dist-in 3.433 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.48 0.219 0.254 A 297 262 7 0 0 0 [[9, 265]] 1.0 7sug CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7SUHA 4 270 476.0 BXI:301 Type1 Active DFGin 6.978 13.326 BLAminus -119.38, 174.44 58.17, 102.88 -112.43, 21.51 291.89, 87.3 -72.91, -23.6 in-in in 8.852 Saltbr-in 3.185 HRD-in -70.43, -44.77 72.79, -5.18 in-in-in SNCiii in-in ActLoopNT-in 2.851 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.3, 155.5 APE9-dihe-na 121.03, -162.94 APE8-dihe-in -122.22, 120.31 APE8-rot-in 306.81 APE67-dihe-in -68.29, -12.17 -40.69, -51.31 APE12-dist-in 9.442 APE11-dist-in 11.601 APE10-dist-in 5.663 APE9-dist-in 3.413 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.46 0.179 0.242 A 297 261 6 0 0 0 [[9, 265]] 1.0 7suh CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7SUIA 4 271 476.0 L80:301 Type1 Active DFGin 7.177 13.406 BLAminus -121.13, 166.3 71.09, 92.03 -104.59, 27.98 295.97, 86.18 -75.46, -22.7 in-in in 8.839 Saltbr-in 2.898 HRD-in -71.84, -40.65 70.78, 1.39 in-in-in SNCiii in-in ActLoopNT-in 2.88 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -167.06, 169.5 APE9-dihe-na 112.95, -154.55 APE8-dihe-in -128.22, 124.64 APE8-rot-in 306.77 APE67-dihe-in -64.51, -20.74 -44.43, -49.5 APE12-dist-in 9.043 APE11-dist-in 11.419 APE10-dist-in 6.15 APE9-dist-in 3.337 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.119 0.198 0.253 A 297 262 6 0 0 0 [[9, 265]] 1.0 7sui CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7SUJB 9 271 476.0 BYL:301 Type1 Active DFGin 7.063 13.351 BLAminus -112.78, 164.5 67.33, 98.63 -107.71, 27.22 294.65, 84.19 -67.75, -27.67 in-in in 9.085 Saltbr-in 2.773 HRD-in -62.4, -45.85 74.76, 2.41 in-in-in SNCiii in-in ActLoopNT-in 3.119 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -162.97, 179.8 APE9-dihe-na 104.39, -157.62 APE8-dihe-in -121.39, 118.56 APE8-rot-in 300.57 APE67-dihe-in -61.22, -23.9 -41.31, -48.21 APE12-dist-in 9.069 APE11-dist-in 11.344 APE10-dist-in 6.076 APE9-dist-in 3.595 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.299 0.236 0.297 B 297 256 7 0 0 0 [[9, 265]] 1.0 7suj CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
8E80A 8 271 476.0 UUF:301 Type1 Active DFGin 6.948 13.561 BLAminus -116.38, 163.51 69.37, 105.0 -111.89, 20.17 292.16, 81.73 -65.53, -30.68 in-in in 8.579 Saltbr-in 2.859 HRD-in -73.57, -45.75 72.69, 0.21 in-in-in SNCiii in-in ActLoopNT-in 2.949 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -163.33, 170.54 APE9-dihe-na 117.83, -149.18 APE8-dihe-in -134.92, 121.74 APE8-rot-in 303.05 APE67-dihe-in -62.91, -20.27 -44.12, -51.23 APE12-dist-in 9.365 APE11-dist-in 11.644 APE10-dist-in 6.142 APE9-dist-in 3.497 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.49 0.209 0.242 A 297 258 6 0 0 0 [[9, 265]] 1.0 8e80 CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
8E81A 4 271 476.0 UU6:301 Type1 Active DFGin 6.979 13.519 BLAminus -118.37, 171.91 69.05, 96.38 -109.23, 17.13 291.1, 85.02 -68.03, -21.82 in-in in 8.54 Saltbr-in 2.811 HRD-in -71.07, -47.85 72.59, 1.56 in-in-in SNCiii in-in ActLoopNT-in 2.955 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.53, 170.33 APE9-dihe-na 117.5, -149.69 APE8-dihe-in -131.89, 120.45 APE8-rot-in 306.67 APE67-dihe-in -61.07, -20.65 -40.19, -52.75 APE12-dist-in 9.097 APE11-dist-in 11.72 APE10-dist-in 6.209 APE9-dist-in 3.5 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.62 0.202 0.232 A 297 260 8 0 0 0 [[9, 265]] 1.0 8e81 CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
8SIVA 4 271 476.0 ZXH:301 Type1 Active DFGin 7.059 13.482 BLAminus -115.5, 167.7 64.71, 99.66 -107.46, 23.74 294.38, 80.14 -66.51, -23.78 in-in in 8.877 Saltbr-in 2.711 HRD-in -72.41, -42.95 71.54, 5.65 in-in-in SNCiii in-in ActLoopNT-in 2.912 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -163.84, 161.6 APE9-dihe-na 121.92, -152.74 APE8-dihe-in -132.25, 119.29 APE8-rot-in 305.39 APE67-dihe-in -62.23, -20.9 -40.75, -52.74 APE12-dist-in 9.191 APE11-dist-in 11.416 APE10-dist-in 6.076 APE9-dist-in 3.417 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.759 0.212 0.251 A 297 262 6 0 0 0 [[9, 265]] 1.0 8siv CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
8SIWA 4 271 476.0 ZXL:301 Type1 Active DFGin 6.994 13.683 BLAminus -113.76, 162.62 69.21, 98.13 -108.28, 26.75 295.75, 74.32 -69.16, -23.41 in-in in 8.71 Saltbr-in 2.743 HRD-in -66.18, -44.18 72.87, 0.87 in-in-in SNCiii in-in ActLoopNT-in 2.973 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.9, 170.61 APE9-dihe-na 117.9, -150.99 APE8-dihe-in -129.35, 117.55 APE8-rot-in 300.72 APE67-dihe-in -66.83, -19.7 -40.71, -46.21 APE12-dist-in 8.819 APE11-dist-in 11.514 APE10-dist-in 6.096 APE9-dist-in 3.679 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.877 0.221 0.258 A 297 262 6 0 0 0 [[9, 265]] 1.0 8siw CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
8SIWB 4 271 476.0 ZXL:301 Type1 Active DFGin 7.084 13.507 BLAminus -115.42, 169.51 62.16, 96.81 -105.7, 27.61 296.32, 77.65 -65.5, -28.47 in-in in 8.929 Saltbr-in 2.748 HRD-in -74.62, -45.0 78.8, -4.37 in-in-in SNCiii in-in ActLoopNT-in 3.04 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.18, 179.28 APE9-dihe-na 113.08, -160.42 APE8-dihe-in -127.84, 114.47 APE8-rot-in 303.7 APE67-dihe-in -63.25, -25.25 -37.36, -47.37 APE12-dist-in 9.207 APE11-dist-in 11.509 APE10-dist-in 5.964 APE9-dist-in 3.785 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.877 0.221 0.258 B 297 262 6 0 0 0 [[9, 265]] 1.0 8siw CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
8SIXA 8 271 476.0 ZXP:301 Type1 Active DFGin 7.025 13.666 BLAminus -113.23, 174.49 65.61, 89.34 -102.74, 20.94 292.25, 82.21 -67.34, -24.63 in-in in 8.747 Saltbr-in 2.893 HRD-in -71.81, -44.82 73.04, 1.24 in-in-in SNCiii in-in ActLoopNT-in 2.964 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -166.47, 164.55 APE9-dihe-na 122.25, -153.58 APE8-dihe-in -132.43, 118.01 APE8-rot-in 303.52 APE67-dihe-in -63.37, -20.97 -39.74, -51.03 APE12-dist-in 8.859 APE11-dist-in 11.462 APE10-dist-in 6.15 APE9-dist-in 3.581 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.55 0.207 0.238 A 297 258 6 0 0 0 [[9, 265]] 1.0 8six CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
5F4NA 5 271 476.0 5UY:301,5UY:302 Type1,Allosteric Active DFGin 6.85 14.189 BLAminus -128.01, 158.86 63.44, 104.21 -106.87, 19.19 287.19, 84.71 -57.12, -35.21 in-in in 8.538 Saltbr-in 2.765 HRD-in -66.75, -44.88 70.14, 2.2 in-in-in SNCiii in-in ActLoopNT-in 3.016 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.7, 168.71 APE9-dihe-na 117.82, -151.09 APE8-dihe-in -134.05, 123.75 APE8-rot-in 301.55 APE67-dihe-in -60.69, -34.97 -48.53, -42.54 APE12-dist-in 9.306 APE11-dist-in 11.573 APE10-dist-in 6.142 APE9-dist-in 3.384 None None None XRAY 1.91 0.151 0.188 A 273 258 9 0 0 0 [[9, 265]] 1.0 5f4n CAMK_CHEK1_HUMAN CAMK 2.1e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2YM7A 7 271 476.0 YM7:1272,YM7:1273 Type1,Type1 Active DFGin 6.936 14.374 BLAminus -121.61, 152.12 75.02, 94.15 -102.21, 23.7 287.09, 83.66 -64.12, -27.24 in-in in 8.617 Saltbr-in 2.799 HRD-in -75.92, -44.81 73.37, 3.79 in-in-in SNCiii in-in ActLoopNT-in 3.002 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -149.53, 155.48 APE9-dihe-na 116.48, -155.91 APE8-dihe-in -139.15, 124.89 APE8-rot-in 299.54 APE67-dihe-in -64.41, -21.42 -48.34, -47.99 APE12-dist-in 9.246 APE11-dist-in 11.336 APE10-dist-in 6.04 APE9-dist-in 3.28 None None None XRAY 1.81 0.174 0.204 A 289 248 17 0 0 0 [[9, 265]] 1.0 2ym7 CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FSTA 3 270 476.0 HK4:301 Type1.5_Back Active DFGin 7.229 14.501 BLAminus -123.14, 175.81 54.94, 88.88 -99.29, 24.5 281.52, 82.61 -64.88, -24.05 in-in in 8.418 Saltbr-in 2.772 HRD-in -75.07, -48.0 73.01, 1.34 in-in-in SNCiii in-in ActLoopNT-in 2.943 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.01, 150.39 APE9-dihe-na 119.8, -156.63 APE8-dihe-in -133.38, 118.41 APE8-rot-in 301.61 APE67-dihe-in -63.43, -18.37 -42.48, -49.9 APE12-dist-in 9.187 APE11-dist-in 11.315 APE10-dist-in 5.732 APE9-dist-in 3.259 None None CSO168 XRAY 1.9 0.167 0.185 A 269 254 14 0 0 0 [[9, 265]] 1.0 4fst CAMK_CHEK1_HUMAN CAMK 2e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2AYPA 2 269 476.0 43A:270 Type1.5_Back Active DFGin 6.973 14.49 BLAminus -138.37, 179.8 49.32, 90.63 -98.25, 15.47 278.28, 78.06 -54.29, -32.89 in-in in 8.803 Saltbr-in 2.757 HRD-in -73.62, -38.68 66.73, -2.61 in-in-in SNCiii in-in ActLoopNT-in 2.994 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na 176.43, 157.28 APE9-dihe-na 129.59, -138.97 APE8-dihe-in -134.95, 126.35 APE8-rot-in 306.63 APE67-dihe-in -76.36, 18.56 -42.31, -52.83 APE12-dist-in 9.588 APE11-dist-in 11.831 APE10-dist-in 6.529 APE9-dist-in 3.223 None None None XRAY 2.9 0.209 0.314 A 269 268 0 0 0 0 [[9, 265]] 1.0 2ayp CAMK_CHEK1_HUMAN CAMK 2e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FSQA 3 280 476.0 HK3:300 Type1.5_Back Active DFGin 6.999 14.384 BLAminus -129.58, 171.1 67.76, 85.3 -96.8, 25.85 288.0, 84.66 -67.55, -27.91 in-in in 8.985 Saltbr-in 2.905 HRD-in -68.52, -48.32 74.72, 0.91 in-in-in SNCiii in-in ActLoopNT-in 2.947 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.05, 162.64 APE9-dihe-na 118.65, -156.24 APE8-dihe-in -131.59, 116.15 APE8-rot-in 306.21 APE67-dihe-in -63.38, -21.02 -38.07, -48.66 APE12-dist-in 9.125 APE11-dist-in 11.441 APE10-dist-in 5.932 APE9-dist-in 3.308 None None None XRAY 2.4 0.177 0.216 A 279 263 15 0 0 0 [[9, 265]] 1.0 4fsq CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FTKA 3 280 476.0 H9K:301 Type1.5_Back Active DFGin 7.006 14.35 BLAminus -130.82, 170.32 67.66, 91.42 -102.43, 26.27 286.08, 87.58 -70.64, -27.6 in-in in 8.994 Saltbr-in 3.235 HRD-in -69.86, -48.19 74.44, -1.22 in-in-in SNCiii in-in ActLoopNT-in 3.018 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.22, 148.4 APE9-dihe-na 116.64, -159.27 APE8-dihe-in -130.65, 118.83 APE8-rot-in 306.3 APE67-dihe-in -62.59, -20.66 -41.67, -49.52 APE12-dist-in 9.226 APE11-dist-in 11.077 APE10-dist-in 5.707 APE9-dist-in 3.362 None None None XRAY 2.3 0.169 0.206 A 279 263 15 0 0 0 [[9, 265]] 1.0 4ftk CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FTMA 3 280 476.0 1HK:301 Type1.5_Back Active DFGin 7.037 14.296 BLAminus -128.77, 171.8 60.97, 91.64 -99.81, 22.79 284.09, 80.44 -66.65, -24.22 in-in in 8.579 Saltbr-in 2.878 HRD-in -76.62, -47.58 73.44, 1.96 in-in-in SNCiii in-in ActLoopNT-in 2.939 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.98, 153.49 APE9-dihe-na 119.69, -162.07 APE8-dihe-in -132.76, 121.74 APE8-rot-in 303.64 APE67-dihe-in -62.56, -20.92 -44.23, -49.67 APE12-dist-in 9.165 APE11-dist-in 11.266 APE10-dist-in 5.796 APE9-dist-in 3.311 None None None XRAY 1.9 0.173 0.201 A 279 263 15 0 0 0 [[9, 265]] 1.0 4ftm CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FTNA 3 271 476.0 2HK:301 Type1.5_Back Active DFGin 7.134 14.394 BLAminus -134.9, 168.86 64.32, 92.93 -102.31, 24.37 287.13, 80.28 -68.67, -25.41 in-in in 9.249 Saltbr-in 2.959 HRD-in -74.17, -47.98 73.35, 5.46 in-in-in SNCiii in-in ActLoopNT-in 2.986 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.01, 152.07 APE9-dihe-na 118.38, -157.24 APE8-dihe-in -135.4, 115.96 APE8-rot-in 302.06 APE67-dihe-in -63.78, -20.34 -42.05, -48.29 APE12-dist-in 9.139 APE11-dist-in 11.227 APE10-dist-in 5.753 APE9-dist-in 3.361 None None CSO168 XRAY 2.02 0.175 0.213 A 279 254 15 0 0 0 [[9, 265]] 1.0 4ftn CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2C3KA 6 270 476.0 ABO:1271 Type1.5_Back Active DFGin 7.015 14.31 BLAminus -126.12, 172.55 61.71, 89.92 -99.46, 20.99 290.88, 86.68 -65.91, -17.18 in-in in 8.634 Saltbr-in 2.867 HRD-in -71.43, -51.73 84.39, -4.25 in-in-in SNCiii in-in ActLoopNT-in 2.771 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.82, 174.75 APE9-dihe-na 109.75, -155.16 APE8-dihe-in -124.52, 126.49 APE8-rot-in 296.43 APE67-dihe-in -70.39, -10.65 -47.18, -47.9 APE12-dist-in 9.19 APE11-dist-in 11.642 APE10-dist-in 6.119 APE9-dist-in 3.546 None None None XRAY 2.6 0.202 0.28 A 297 262 3 0 0 0 [[9, 265]] 1.0 2c3k CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
5OOPA 5 271 476.0 ANP:301 ATPlike Inactive DFGin 7.048 13.858 BLAminus -117.87, 168.06 78.81, 84.96 -99.9, 22.77 292.72, 82.66 -69.65, -23.48 in-out in 9.592 Saltbr-out 3.669 HRD-in -77.29, -47.33 77.92, -0.19 out-in-in SNCoii in-in ActLoopNT-in 2.894 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.46, 169.24 APE9-dihe-na 115.98, -146.93 APE8-dihe-in -135.24, 119.66 APE8-rot-in 302.63 APE67-dihe-in -65.46, -19.69 -46.47, -46.68 APE12-dist-in 8.889 APE11-dist-in 11.835 APE10-dist-in 6.194 APE9-dist-in 3.474 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.7 0.159 0.197 A 297 261 6 0 0 0 [[9, 265]] 1.0 5oop CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
3JVSA 2 272 476.0 AGY:900 Allosteric Inactive DFGin 6.928 14.214 BLAminus -125.08, 149.2 74.51, 96.16 -103.33, 29.41 288.74, 77.48 -69.19, -18.09 in-out in 8.744 Saltbr-out 3.894 HRD-in -76.21, -44.02 77.01, 0.01 out-in-in SNCoii in-in ActLoopNT-in 2.975 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.68, 173.83 APE9-dihe-na 116.0, -152.22 APE8-dihe-in -137.44, 122.36 APE8-rot-in 299.63 APE67-dihe-in -63.34, -19.96 -49.74, -47.01 APE12-dist-in 8.906 APE11-dist-in 11.826 APE10-dist-in 6.303 APE9-dist-in 3.363 None None None XRAY 1.9 0.187 0.215 A 271 256 15 0 0 0 [[9, 265]] 1.0 3jvs CAMK_CHEK1_HUMAN CAMK 2e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2YM5A 8 270 476.0 YM5:1271 Type1 Inactive DFGin 6.786 14.466 BLAminus -123.55, 147.23 77.25, 102.29 -108.76, 31.6 290.44, 81.79 -72.01, -24.72 in-out in 8.919 Saltbr-out 4.289 HRD-in -72.18, -44.74 74.98, -1.55 out-in-in SNCoii in-in ActLoopNT-in 2.975 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.41, 158.56 APE9-dihe-na 115.29, -154.3 APE8-dihe-in -138.66, 120.99 APE8-rot-in 298.7 APE67-dihe-in -59.21, -20.42 -44.81, -50.43 APE12-dist-in 9.454 APE11-dist-in 11.533 APE10-dist-in 5.81 APE9-dist-in 3.285 None None None XRAY 2.03 0.187 0.216 A 289 248 15 0 0 0 [[9, 265]] 1.0 2ym5 CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2YM6A 7 270 476.0 YM6:1271 Type1 Inactive DFGin 6.893 14.067 BLAminus -125.84, 165.3 71.75, 92.1 -105.43, 25.68 289.47, 82.42 -68.26, -25.47 in-out in 8.452 Saltbr-out 3.837 HRD-in -75.24, -45.04 77.01, -2.96 out-in-in SNCoii in-in ActLoopNT-in 2.948 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.04, 173.92 APE9-dihe-na 113.14, -153.56 APE8-dihe-in -135.04, 120.42 APE8-rot-in 305.28 APE67-dihe-in -64.72, -22.15 -41.9, -47.97 APE12-dist-in 9.392 APE11-dist-in 11.658 APE10-dist-in 6.072 APE9-dist-in 3.331 None None None XRAY 2.01 0.182 0.222 A 289 253 11 0 0 0 [[9, 265]] 1.0 2ym6 CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2HXQA 2 276 476.0 373:324 Type1 Inactive DFGin 6.739 14.205 BLAminus -131.67, 172.11 66.93, 93.04 -104.3, 25.93 289.41, 78.77 -64.88, -25.49 in-out in 8.872 Saltbr-out 3.653 HRD-in -75.67, -44.04 71.24, 1.14 out-in-in SNCoii in-in ActLoopNT-in 2.874 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.54, 168.7 APE9-dihe-na 121.75, -149.53 APE8-dihe-in -134.54, 121.63 APE8-rot-in 305.27 APE67-dihe-in -57.28, -30.11 -32.05, -58.28 APE12-dist-in 9.137 APE11-dist-in 11.546 APE10-dist-in 5.998 APE9-dist-in 3.286 None None None XRAY 2.0 0.23 0.26 A 322 272 3 0 0 0 [[9, 265]] 1.0 2hxq CAMK_CHEK1_HUMAN CAMK 3.8e-71 245.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2HY0A 2 280 476.0 306:324 Type1 Inactive DFGin 6.873 14.366 BLAminus -129.7, 171.08 67.18, 87.46 -100.9, 29.66 290.46, 79.38 -69.54, -24.68 in-out in 8.869 Saltbr-out 4.312 HRD-in -71.61, -47.13 73.77, -1.04 out-in-in SNCoii in-in ActLoopNT-in 2.998 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.22, 153.49 APE9-dihe-na 120.42, -158.94 APE8-dihe-in -133.35, 116.61 APE8-rot-in 305.54 APE67-dihe-in -62.0, -23.74 -31.71, -52.29 APE12-dist-in 9.12 APE11-dist-in 11.277 APE10-dist-in 5.784 APE9-dist-in 3.286 None None None XRAY 1.7 0.23 0.234 A 322 272 7 0 0 0 [[9, 265]] 1.0 2hy0 CAMK_CHEK1_HUMAN CAMK 3.8e-71 245.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
5OORA 3 283 476.0 STU:301 Type1 Inactive DFGin 7.196 13.603 BLAminus -121.08, 157.07 78.53, 94.76 -101.65, 21.08 291.71, 78.34 -70.5, -20.28 in-out in 9.325 Saltbr-out 5.381 HRD-in -78.63, -43.76 73.29, -4.94 out-in-in SNCoii in-in ActLoopNT-in 2.906 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.81, 173.83 APE9-dihe-na 115.52, -146.73 APE8-dihe-in -140.31, 116.76 APE8-rot-in 299.43 APE67-dihe-in -68.59, -17.99 -48.27, -41.97 APE12-dist-in 9.154 APE11-dist-in 11.744 APE10-dist-in 6.296 APE9-dist-in 3.597 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.9 0.167 0.208 A 297 273 8 0 0 0 [[9, 265]] 1.0 5oor CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7BJMA 5 270 476.0 TW2:301 Type1 Inactive DFGin 6.951 14.027 BLAminus -115.22, 158.82 79.76, 90.94 -98.94, 22.09 292.53, 79.67 -71.79, -20.79 in-out in 9.57 Saltbr-out 3.631 HRD-in -73.21, -47.72 78.68, -2.75 out-in-in SNCoii in-in ActLoopNT-in 2.921 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -163.02, 174.96 APE9-dihe-na 106.83, -152.13 APE8-dihe-in -127.07, 123.19 APE8-rot-in 302.79 APE67-dihe-in -68.0, -22.23 -51.4, -44.18 APE12-dist-in 8.748 APE11-dist-in 11.505 APE10-dist-in 6.128 APE9-dist-in 3.592 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.3 0.178 0.231 A 297 256 10 0 0 0 [[9, 265]] 1.0 7bjm CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
7SUJA 9 271 476.0 BYL:301 Type1 Inactive DFGin 6.939 13.626 BLAminus -118.6, 167.38 74.89, 93.53 -107.57, 23.59 297.11, 81.28 -67.67, -15.39 in-out in 9.057 Saltbr-out 4.109 HRD-in -70.24, -40.44 73.4, -9.88 out-in-in SNCoii in-in ActLoopNT-in 3.173 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.12, 168.37 APE9-dihe-na 116.82, -153.6 APE8-dihe-in -125.53, 126.35 APE8-rot-in 298.09 APE67-dihe-in -67.17, -13.71 -45.66, -47.75 APE12-dist-in 8.965 APE11-dist-in 11.569 APE10-dist-in 6.122 APE9-dist-in 3.731 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.299 0.236 0.297 A 297 256 7 0 0 0 [[9, 265]] 1.0 7suj CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
2E9NA 2 270 476.0 76A:1001 Type1.5_Back Inactive DFGin 7.095 14.381 BLAminus -144.96, 155.54 84.19, 89.92 -105.99, 27.11 297.21, 81.31 -68.23, -13.23 in-out in 9.29 Saltbr-out 4.122 HRD-in -69.34, -48.43 74.18, 2.16 out-in-in SNCoii in-in ActLoopNT-in 3.164 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -164.16, 157.24 APE9-dihe-na 135.09, -139.89 APE8-dihe-in -143.44, 117.3 APE8-rot-in 325.96 APE67-dihe-in -71.39, -22.32 -31.33, -47.78 APE12-dist-in 9.444 APE11-dist-in 11.794 APE10-dist-in 6.37 APE9-dist-in 3.467 None None None XRAY 2.5 0.238 0.305 A 269 269 0 0 0 0 [[9, 265]] 1.0 2e9n CAMK_CHEK1_HUMAN CAMK 2e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
4FTLA 3 280 476.0 H0K:301 Type1.5_Back Inactive DFGin 7.027 14.357 BLAminus -129.66, 168.09 67.87, 93.63 -105.0, 27.18 288.37, 90.96 -69.12, -30.84 in-out in 8.927 Saltbr-out 3.853 HRD-in -70.27, -47.56 74.38, -3.05 out-in-in SNCoii in-in ActLoopNT-in 3.067 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.74, 148.9 APE9-dihe-na 119.92, -158.25 APE8-dihe-in -131.52, 114.92 APE8-rot-in 303.17 APE67-dihe-in -66.03, -16.42 -36.91, -49.5 APE12-dist-in 9.156 APE11-dist-in 11.226 APE10-dist-in 5.738 APE9-dist-in 3.373 None None None XRAY 2.5 0.181 0.226 A 279 263 15 0 0 0 [[9, 265]] 1.0 4ftl CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1

CAMK_CHEK1 (Serine/threonine-protein kinase Chk1)

Total number of chains: 171
Active chains: 160
Family: CAMK
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 171 100.0% AF-O14757-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CHK1_HUMAN 7AKMA O14757 2 271 476.0 AGS:401 ATPlike Active DFGin 6.775 14.143 BLAminus -128.66, 150.55 71.15, 96.3 -103.32, 28.49 292.74, 82.8 -70.74, -21.81 in-in in 9.111 Saltbr-in 2.706 HRD-in -78.28, -45.32 76.75, -0.14 in-in-in SNCiii in-in ActLoopNT-in 3.011 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -163.43, 171.3 APE9-dihe-na 110.38, -147.97 APE8-dihe-in -135.73, 125.59 APE8-rot-in 300.71 APE67-dihe-in -62.97, -17.75 -56.42, -42.48 APE12-dist-in 9.309 APE11-dist-in 11.674 APE10-dist-in 6.171 APE9-dist-in 3.407 D10R None None XRAY 1.93 0.199 0.242 A 298 270 0 0 0 0 [[9, 265]] 1.0 7akm Homo sapiens CAMK_CHEK1_HUMAN CAMK 3.4e-71 245.5 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 3JVRA O14757 2 272 476.0 AGX:901 Allosteric Active DFGin 6.872 14.177 BLAminus -127.98, 150.64 73.31, 94.81 -103.55, 30.03 289.43, 82.54 -69.18, -19.03 in-in in 8.831 Saltbr-in 2.689 HRD-in -74.95, -44.7 78.13, -0.66 in-in-in SNCiii in-in ActLoopNT-in 2.948 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.38, 173.26 APE9-dihe-na 116.8, -150.87 APE8-dihe-in -139.69, 123.15 APE8-rot-in 300.09 APE67-dihe-in -61.84, -23.11 -49.41, -48.15 APE12-dist-in 8.931 APE11-dist-in 11.813 APE10-dist-in 6.298 APE9-dist-in 3.406 None None None XRAY 1.76 0.202 0.225 A 271 258 13 0 0 0 [[9, 265]] 1.0 3jvr Homo sapiens CAMK_CHEK1_HUMAN CAMK 2e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 3F9NA O14757 7 270 476.0 38M:324 Allosteric Active DFGin 6.871 14.306 BLAminus -120.26, 153.9 73.21, 93.52 -100.46, 25.66 293.37, 83.17 -66.45, -28.23 in-in in 8.857 Saltbr-in 2.555 HRD-in -79.56, -43.26 73.24, -2.23 in-in-in SNCiii in-in ActLoopNT-in 3.014 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.39, 152.53 APE9-dihe-na 120.62, -163.45 APE8-dihe-in -134.2, 121.67 APE8-rot-in 301.99 APE67-dihe-in -60.59, -25.68 -41.41, -51.19 APE12-dist-in 9.146 APE11-dist-in 11.147 APE10-dist-in 5.801 APE9-dist-in 3.398 None None None XRAY 1.9 0.184 0.216 A 322 253 11 0 0 0 [[9, 265]] 1.0 3f9n Homo sapiens CAMK_CHEK1_HUMAN CAMK 3.8e-71 245.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN AF-O14757-K1A O14757 1 273 476.0 No_ligand No_ligand Active DFGin 6.908 13.879 BLAminus -126.41, 173.77 59.88, 75.65 -83.37, 18.3 292.07, 88.25 -61.72, -28.43 in-in in 8.997 Saltbr-in 2.756 HRD-in -81.68, -47.56 71.58, -4.39 in-in-in SNCiii in-in ActLoopNT-in 3.002 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -162.33, 169.83 APE9-dihe-na 111.71, 175.87 APE8-dihe-in -92.2, 123.21 APE8-rot-in 308.56 APE67-dihe-in -63.62, -24.82 -49.79, -44.17 APE12-dist-in 9.178 APE11-dist-in 11.671 APE10-dist-in 6.144 APE9-dist-in 3.634 None None None AF2 -1.0 1.0 1.0 A 273 273 0 0 0 0 [[9, 265]] 1.0 AF-O14757-K1 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.1e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN AF-O14757-K3A O14757 1 273 476.0 No_ligand No_ligand Active DFGin 6.65 13.867 BLAminus -123.65, -177.83 47.33, 73.45 -76.38, 14.64 294.74, 95.75 -58.94, -31.14 in-in in 8.964 Saltbr-in 2.728 HRD-in -82.53, -48.74 68.72, 4.29 in-in-in SNCiii in-in ActLoopNT-in 2.933 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.6, 168.78 APE9-dihe-na 104.0, 175.5 APE8-dihe-in -88.64, 126.31 APE8-rot-in 306.94 APE67-dihe-in -61.16, -29.27 -52.3, -41.96 APE12-dist-in 9.368 APE11-dist-in 11.541 APE10-dist-in 5.913 APE9-dist-in 3.334 None None None AF2 -1.0 1.0 1.0 A 273 273 0 0 0 0 [[9, 265]] 1.0 AF-O14757-K3 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.1e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 1IA8A O14757 2 276 476.0 No_ligand No_ligand Active DFGin 6.901 14.276 BLAminus -124.2, 154.39 68.94, 96.97 -102.1, 26.7 291.65, 79.3 -65.06, -22.41 in-in in 8.89 Saltbr-in 2.735 HRD-in -75.22, -41.37 69.04, 2.45 in-in-in SNCiii in-in ActLoopNT-in 2.925 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.12, 169.49 APE9-dihe-na 119.83, -148.37 APE8-dihe-in -135.5, 118.95 APE8-rot-in 302.64 APE67-dihe-in -61.39, -22.34 -35.34, -54.92 APE12-dist-in 8.917 APE11-dist-in 11.909 APE10-dist-in 6.335 APE9-dist-in 3.331 None None None XRAY 1.7 0.216 0.235 A 289 272 3 0 0 0 [[9, 265]] 1.0 1ia8 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7AKMB O14757 2 269 476.0 No_ligand No_ligand Active DFGin 6.729 14.236 BLAminus -131.2, 148.86 72.72, 94.14 -102.13, 30.13 293.9, 82.86 -70.24, -23.15 in-in in 8.062 Saltbr-in 2.923 HRD-in -73.93, -45.68 78.44, -0.49 in-in-in SNCiii in-in ActLoopNT-in 3.083 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.14, 171.41 APE9-dihe-na 115.69, -149.76 APE8-dihe-in -139.3, 121.55 APE8-rot-in 304.35 APE67-dihe-in -60.59, -21.72 -51.07, -46.17 APE12-dist-in 9.473 APE11-dist-in 11.679 APE10-dist-in 6.174 APE9-dist-in 3.588 D10R None None XRAY 1.93 0.199 0.242 B 298 268 0 0 0 0 [[9, 265]] 1.0 7akm Homo sapiens CAMK_CHEK1_HUMAN CAMK 3.4e-71 245.5 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 1ZYSA O14757 3 273 476.0 199:400 Type1 Active DFGin 6.822 14.043 BLAminus -125.46, 168.25 66.65, 88.29 -97.37, 27.49 292.37, 83.58 -68.83, -18.69 in-in in 9.041 Saltbr-in 2.559 HRD-in -84.01, -42.62 72.63, -1.0 in-in-in SNCiii in-in ActLoopNT-in 2.94 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.0, 171.72 APE9-dihe-na 116.11, -147.59 APE8-dihe-in -140.51, 125.84 APE8-rot-in 300.55 APE67-dihe-in -63.09, -21.21 -45.55, -50.46 APE12-dist-in 8.807 APE11-dist-in 12.021 APE10-dist-in 6.423 APE9-dist-in 3.289 None None None XRAY 1.7 0.227 0.26 A 273 271 0 0 0 0 [[9, 265]] 1.0 1zys Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-71 245.0 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2E9VA O14757 2 269 476.0 85A:1001 Type1 Active DFGin 6.975 14.637 BLAminus -131.54, 177.83 55.26, 98.09 -109.61, 30.41 286.66, 68.67 -62.59, -29.32 in-in in 8.701 Saltbr-in 2.67 HRD-in -76.45, -37.92 59.71, 14.92 in-in-in SNCiii in-in ActLoopNT-in 2.889 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.78, 168.23 APE9-dihe-na 122.1, -169.86 APE8-dihe-in -111.29, 110.84 APE8-rot-in 305.57 APE67-dihe-in -47.02, -35.65 -25.69, -68.51 APE12-dist-in 9.434 APE11-dist-in 11.908 APE10-dist-in 6.143 APE9-dist-in 3.595 None None None XRAY 2.0 0.279 0.333 A 268 268 0 0 0 0 [[9, 265]] 1.0 2e9v Homo sapiens CAMK_CHEK1_HUMAN CAMK 2e-71 246.3 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2E9VB O14757 2 269 476.0 85A:2001 Type1 Active DFGin 6.918 14.189 BLAminus -126.14, 170.02 63.09, 96.2 -109.54, 31.48 299.02, 75.08 -66.55, -19.9 in-in in 8.259 Saltbr-in 2.694 HRD-in -68.57, -49.41 72.45, 8.8 in-in-in SNCiii in-in ActLoopNT-in 3.096 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.77, 165.61 APE9-dihe-na 116.5, -156.5 APE8-dihe-in -122.27, 105.18 APE8-rot-in 303.15 APE67-dihe-in -59.07, -28.34 -21.14, -51.59 APE12-dist-in 9.033 APE11-dist-in 11.859 APE10-dist-in 6.153 APE9-dist-in 3.462 None None None XRAY 2.0 0.279 0.333 B 268 268 0 0 0 0 [[9, 265]] 1.0 2e9v Homo sapiens CAMK_CHEK1_HUMAN CAMK 2e-71 246.3 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2E9OA O14757 2 270 476.0 A58:1001 Type1 Active DFGin 6.931 14.179 BLAminus -128.32, 168.44 64.14, 94.25 -103.44, 34.01 291.92, 79.18 -71.63, -19.2 in-in in 8.896 Saltbr-in 2.777 HRD-in -74.31, -47.15 72.74, 4.43 in-in-in SNCiii in-in ActLoopNT-in 2.982 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -150.26, 171.72 APE9-dihe-na 111.42, -153.4 APE8-dihe-in -133.8, 111.32 APE8-rot-in 302.29 APE67-dihe-in -62.45, -26.48 -26.55, -51.1 APE12-dist-in 9.089 APE11-dist-in 11.704 APE10-dist-in 6.009 APE9-dist-in 3.225 None None None XRAY 2.1 0.229 0.259 A 269 269 0 0 0 0 [[9, 265]] 1.0 2e9o Homo sapiens CAMK_CHEK1_HUMAN CAMK 2e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2E9PA O14757 2 270 476.0 77A:1001 Type1 Active DFGin 7.029 14.727 BLAminus -133.16, 178.72 63.58, 82.88 -105.74, 27.5 294.08, 87.1 -69.81, -10.86 in-in in 8.751 Saltbr-in 3.178 HRD-in -78.51, -52.51 75.63, -2.35 in-in-in SNCiii in-in ActLoopNT-in 2.983 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.13, 159.0 APE9-dihe-na 119.96, -161.72 APE8-dihe-in -125.67, 103.78 APE8-rot-in 300.79 APE67-dihe-in -64.0, -31.79 -16.61, -54.34 APE12-dist-in 9.52 APE11-dist-in 11.427 APE10-dist-in 5.651 APE9-dist-in 3.067 None None None XRAY 2.6 0.237 0.296 A 269 269 0 0 0 0 [[9, 265]] 1.0 2e9p Homo sapiens CAMK_CHEK1_HUMAN CAMK 2e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2E9UA O14757 2 270 476.0 A25:1001 Type1 Active DFGin 7.011 14.113 BLAminus -132.04, 172.65 62.85, 89.38 -101.09, 30.5 293.08, 81.27 -73.07, -16.47 in-in in 8.634 Saltbr-in 2.594 HRD-in -70.01, -43.61 71.24, 2.07 in-in-in SNCiii in-in ActLoopNT-in 3.004 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.27, 170.1 APE9-dihe-na 118.87, -157.35 APE8-dihe-in -129.87, 116.69 APE8-rot-in 299.78 APE67-dihe-in -60.89, -25.73 -32.98, -51.09 APE12-dist-in 9.224 APE11-dist-in 11.666 APE10-dist-in 5.958 APE9-dist-in 3.289 None None None XRAY 2.0 0.242 0.277 A 269 269 0 0 0 0 [[9, 265]] 1.0 2e9u Homo sapiens CAMK_CHEK1_HUMAN CAMK 2e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2GHGA O14757 2 270 476.0 A53:1 Type1 Active DFGin 6.886 14.53 BLAminus -166.32, 170.51 70.16, 71.94 -87.0, 41.41 289.83, 76.15 -75.14, -46.9 in-in in 8.977 Saltbr-in 3.136 HRD-in -93.04, -17.87 49.7, 7.2 in-in-in SNCiii in-in ActLoopNT-in 3.17 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -119.48, 116.46 APE9-dihe-na -170.15, -133.06 APE8-dihe-in -140.13, 110.94 APE8-rot-in 291.04 APE67-dihe-in -68.96, -50.13 -35.06, -49.54 APE12-dist-in 8.896 APE11-dist-in 11.861 APE10-dist-in 6.332 APE9-dist-in 3.697 None None None XRAY 3.5 0.24 0.314 A 269 269 0 0 0 0 [[9, 265]] 1.0 2ghg Homo sapiens CAMK_CHEK1_HUMAN CAMK 2e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2YWPA O14757 2 270 476.0 A42:1 Type1 Active DFGin 6.846 14.194 BLAminus -128.34, 170.16 65.69, 87.88 -101.03, 37.84 293.97, 84.7 -68.74, -18.33 in-in in 8.773 Saltbr-in 2.586 HRD-in -63.32, -40.53 66.09, 3.77 in-in-in SNCiii in-in ActLoopNT-in 2.993 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.27, 147.17 APE9-dihe-na 141.47, -143.91 APE8-dihe-in -127.52, 116.49 APE8-rot-in 286.38 APE67-dihe-in -56.51, -33.62 -29.01, -64.65 APE12-dist-in 9.177 APE11-dist-in 11.697 APE10-dist-in 6.129 APE9-dist-in 3.396 None None None XRAY 2.9 0.242 0.297 A 269 269 0 0 0 0 [[9, 265]] 1.0 2ywp Homo sapiens CAMK_CHEK1_HUMAN CAMK 2e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 3OT3A O14757 4 272 476.0 22K:1 Type1 Active DFGin 7.072 14.088 BLAminus -119.38, 162.39 68.19, 101.86 -107.35, 22.12 289.5, 79.69 -65.92, -24.4 in-in in 8.404 Saltbr-in 2.644 HRD-in -72.88, -42.96 74.77, -4.22 in-in-in SNCiii in-in ActLoopNT-in 2.989 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -170.04, 168.72 APE9-dihe-na 114.72, -154.18 APE8-dihe-in -135.81, 120.72 APE8-rot-in 300.78 APE67-dihe-in -62.65, -21.04 -40.11, -52.91 APE12-dist-in 9.089 APE11-dist-in 11.425 APE10-dist-in 6.232 APE9-dist-in 3.377 None None None XRAY 1.44 0.185 0.202 A 273 261 8 0 0 0 [[9, 265]] 1.0 3ot3 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.1e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 3OT8A O14757 4 272 476.0 MI5:1 Type1 Active DFGin 7.0 14.027 BLAminus -120.24, 163.62 66.2, 100.88 -107.87, 26.52 289.17, 80.05 -67.79, -28.22 in-in in 8.382 Saltbr-in 2.676 HRD-in -76.11, -44.26 74.22, -4.28 in-in-in SNCiii in-in ActLoopNT-in 2.949 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.29, 156.87 APE9-dihe-na 115.01, -158.59 APE8-dihe-in -135.82, 120.71 APE8-rot-in 300.89 APE67-dihe-in -59.91, -23.22 -36.95, -56.24 APE12-dist-in 9.322 APE11-dist-in 11.252 APE10-dist-in 5.879 APE9-dist-in 3.304 None None None XRAY 1.645 0.179 0.202 A 273 255 14 0 0 0 [[9, 265]] 1.0 3ot8 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.1e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 3PA3A O14757 4 272 476.0 C70:1 Type1 Active DFGin 6.973 14.368 BLAminus -134.57, 168.81 69.42, 75.54 -91.88, 20.16 289.95, 77.58 -62.79, -19.4 in-in in 9.078 Saltbr-in 2.824 HRD-in -73.66, -45.33 74.44, -1.43 in-in-in SNCiii in-in ActLoopNT-in 2.937 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.61, 167.51 APE9-dihe-na 121.86, -151.66 APE8-dihe-in -134.95, 118.7 APE8-rot-in 302.9 APE67-dihe-in -63.51, -20.47 -39.03, -52.39 APE12-dist-in 8.919 APE11-dist-in 11.74 APE10-dist-in 6.138 APE9-dist-in 3.414 None None None XRAY 1.4 0.193 0.213 A 273 261 8 0 0 0 [[9, 265]] 1.0 3pa3 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.1e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 3PA4A O14757 6 272 476.0 C72:1 Type1 Active DFGin 6.965 14.377 BLAminus -132.17, 169.17 65.58, 76.35 -92.09, 21.91 286.75, 76.98 -63.13, -19.98 in-in in 9.009 Saltbr-in 2.792 HRD-in -74.13, -43.12 73.54, -3.04 in-in-in SNCiii in-in ActLoopNT-in 2.952 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.98, 170.48 APE9-dihe-na 119.01, -149.2 APE8-dihe-in -135.82, 117.84 APE8-rot-in 301.84 APE67-dihe-in -60.82, -20.24 -35.81, -56.24 APE12-dist-in 8.993 APE11-dist-in 11.732 APE10-dist-in 6.131 APE9-dist-in 3.403 None None None XRAY 1.59 0.225 0.25 A 273 259 8 0 0 0 [[9, 265]] 1.0 3pa4 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.1e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 3PA5A O14757 3 272 476.0 C73:1 Type1 Active DFGin 6.9 14.148 BLAminus -129.79, 167.68 66.08, 79.04 -93.62, 22.86 289.4, 76.66 -63.59, -21.02 in-in in 8.741 Saltbr-in 2.81 HRD-in -72.95, -46.5 75.39, -2.75 in-in-in SNCiii in-in ActLoopNT-in 2.904 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.77, 168.26 APE9-dihe-na 121.59, -150.46 APE8-dihe-in -134.42, 118.81 APE8-rot-in 303.4 APE67-dihe-in -64.55, -17.29 -34.12, -56.19 APE12-dist-in 9.139 APE11-dist-in 11.726 APE10-dist-in 6.199 APE9-dist-in 3.403 None None None XRAY 1.7 0.185 0.204 A 273 257 13 0 0 0 [[9, 265]] 1.0 3pa5 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.1e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 3U9NA O14757 7 272 476.0 09H:301 Type1 Active DFGin 6.902 14.222 BLAminus -129.35, 168.34 66.97, 89.35 -103.09, 30.47 290.62, 76.37 -69.94, -19.85 in-in in 8.941 Saltbr-in 2.98 HRD-in -75.25, -47.19 74.3, 0.38 in-in-in SNCiii in-in ActLoopNT-in 2.967 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.97, 166.31 APE9-dihe-na 118.13, -152.42 APE8-dihe-in -130.48, 118.2 APE8-rot-in 302.9 APE67-dihe-in -59.94, -25.46 -32.53, -57.85 APE12-dist-in 8.944 APE11-dist-in 11.526 APE10-dist-in 6.123 APE9-dist-in 3.378 None None None XRAY 1.85 0.197 0.229 A 273 258 8 0 0 0 [[9, 265]] 1.0 3u9n Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.1e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4JIKA O14757 4 272 476.0 1KO:301 Type1 Active DFGin 6.844 14.415 BLAminus -132.96, 171.39 63.69, 79.56 -94.29, 22.22 287.36, 75.0 -62.33, -21.36 in-in in 9.309 Saltbr-in 3.102 HRD-in -69.23, -49.52 74.37, -4.01 in-in-in SNCiii in-in ActLoopNT-in 2.93 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.1, 158.36 APE9-dihe-na 125.39, -154.3 APE8-dihe-in -132.51, 118.9 APE8-rot-in 299.47 APE67-dihe-in -59.75, -20.56 -32.5, -57.47 APE12-dist-in 9.737 APE11-dist-in 11.499 APE10-dist-in 5.654 APE9-dist-in 3.284 None None None XRAY 1.9 0.211 0.237 A 273 256 13 0 0 0 [[9, 265]] 1.0 4jik Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.1e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2X8EA O14757 9 270 476.0 X8E:1271 Type1 Active DFGin 6.973 14.28 BLAminus -124.04, 146.44 71.63, 110.62 -118.45, 20.59 294.1, 101.48 -77.34, -5.52 in-in in 8.746 Saltbr-in 2.746 HRD-in -57.57, -35.91 68.86, -17.53 in-in-in SNCiii in-in ActLoopNT-in 3.18 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.78, 160.7 APE9-dihe-na 116.57, -159.67 APE8-dihe-in -130.77, 130.86 APE8-rot-in 326.48 APE67-dihe-in -78.63, -14.78 -51.23, -40.57 APE12-dist-in 9.614 APE11-dist-in 11.717 APE10-dist-in 5.962 APE9-dist-in 3.777 None None None XRAY 2.5 0.235 0.309 A 276 259 3 0 0 0 [[9, 265]] 1.0 2x8e Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.2e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2YDJA O14757 8 269 476.0 YDJ:1270 Type1 Active DFGin 6.852 14.043 BLAminus -131.16, 158.84 66.63, 79.17 -91.38, 22.19 287.3, 85.3 -65.89, -18.2 in-in in 8.595 Saltbr-in 3.078 HRD-in -81.14, -43.61 73.59, 1.69 in-in-in SNCiii in-in ActLoopNT-in 2.962 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.06, 143.33 APE9-dihe-na 116.46, -165.7 APE8-dihe-in -122.14, 128.4 APE8-rot-in 305.87 APE67-dihe-in -59.89, -24.88 -48.54, -44.68 APE12-dist-in 8.904 APE11-dist-in 11.531 APE10-dist-in 5.992 APE9-dist-in 3.703 None None CSS57,CSS168 XRAY 1.85 0.231 0.274 A 276 254 8 0 0 0 [[9, 265]] 1.0 2ydj Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.2e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2YDJB O14757 9 269 476.0 YDJ:1270 Type1 Active DFGin 6.856 13.953 BLAminus -128.99, 157.39 65.68, 84.37 -94.19, 20.4 292.81, 85.67 -57.98, -21.82 in-in in 8.577 Saltbr-in 2.727 HRD-in -82.83, -45.03 78.79, -0.66 in-in-in SNCiii in-in ActLoopNT-in 2.925 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.08, 148.59 APE9-dihe-na 113.79, -160.81 APE8-dihe-in -130.66, 123.13 APE8-rot-in 312.19 APE67-dihe-in -61.27, -23.44 -46.66, -47.69 APE12-dist-in 8.761 APE11-dist-in 11.504 APE10-dist-in 5.881 APE9-dist-in 3.486 None None CSS57,CSS168 XRAY 1.85 0.231 0.274 B 276 253 8 0 0 0 [[9, 265]] 1.0 2ydj Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.2e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2YDKA O14757 3 270 476.0 YDK:1277 Type1 Active DFGin 6.815 13.863 BLAminus -134.73, 157.08 71.98, 82.41 -98.21, 25.23 288.97, 82.35 -65.36, -21.41 in-in in 8.597 Saltbr-in 2.426 HRD-in -84.22, -45.96 71.26, 3.83 in-in-in SNCiii in-in ActLoopNT-in 2.985 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -80.97, 147.05 APE9-dihe-na 136.33, 158.87 APE8-dihe-in -85.44, 119.21 APE8-rot-in 306.85 APE67-dihe-in -66.77, -13.0 -53.89, -41.91 APE12-dist-in 8.362 APE11-dist-in 11.699 APE10-dist-in 5.907 APE9-dist-in 3.635 None None None XRAY 1.9 0.183 0.226 A 276 263 5 0 0 0 [[9, 265]] 1.0 2ydk Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.2e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2YERA O14757 2 269 476.0 TQ1:1270 Type1 Active DFGin 6.756 14.258 BLAminus -124.59, 145.71 75.35, 98.7 -104.18, 25.73 293.91, 82.78 -62.89, -29.92 in-in in 8.96 Saltbr-in 2.625 HRD-in -76.13, -45.9 72.42, 1.41 in-in-in SNCiii in-in ActLoopNT-in 2.96 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.32, 169.84 APE9-dihe-na 113.06, -165.98 APE8-dihe-in -114.1, 119.87 APE8-rot-in 298.55 APE67-dihe-in -61.8, -19.78 -47.68, -48.11 APE12-dist-in 8.584 APE11-dist-in 11.797 APE10-dist-in 6.106 APE9-dist-in 3.296 None None None XRAY 1.83 0.147 0.175 A 276 268 0 0 0 0 [[9, 265]] 1.0 2yer Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.2e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2YEXA O14757 2 270 476.0 YEX:1278 Type1 Active DFGin 6.893 14.384 BLAminus -127.36, 145.61 77.89, 95.73 -100.45, 22.36 290.83, 83.74 -60.39, -34.45 in-in in 8.981 Saltbr-in 2.687 HRD-in -75.84, -47.88 76.45, 1.35 in-in-in SNCiii in-in ActLoopNT-in 2.988 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.42, 168.54 APE9-dihe-na 112.0, -176.49 APE8-dihe-in -102.85, 121.8 APE8-rot-in 300.84 APE67-dihe-in -62.59, -19.14 -49.95, -47.33 APE12-dist-in 8.615 APE11-dist-in 11.848 APE10-dist-in 6.118 APE9-dist-in 3.454 None None None XRAY 1.3 0.135 0.164 A 276 269 0 0 0 0 [[9, 265]] 1.0 2yex Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.2e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 6FC8A O14757 2 270 476.0 D4Q:302 Type1 Active DFGin 6.976 14.302 BLAminus -130.25, 169.7 63.03, 80.83 -96.98, 23.05 287.14, 83.19 -63.88, -21.11 in-in in 9.12 Saltbr-in 2.842 HRD-in -75.73, -49.32 70.88, 5.08 in-in-in SNCiii in-in ActLoopNT-in 2.936 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -147.0, 168.69 APE9-dihe-na 112.45, -173.34 APE8-dihe-in -100.21, 119.57 APE8-rot-in 309.11 APE67-dihe-in -65.13, -15.07 -45.17, -47.91 APE12-dist-in 8.643 APE11-dist-in 11.84 APE10-dist-in 6.238 APE9-dist-in 3.433 None None None XRAY 1.61 0.192 0.225 A 276 269 0 0 0 0 [[9, 265]] 1.0 6fc8 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.2e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 6FCFA O14757 9 269 476.0 D58:301 Type1 Active DFGin 7.066 14.096 BLAminus -128.16, 162.61 60.99, 87.16 -94.65, 19.56 290.65, 86.02 -63.74, -20.3 in-in in 8.493 Saltbr-in 2.851 HRD-in -74.13, -49.85 68.69, 7.55 in-in-in SNCiii in-in ActLoopNT-in 3.065 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -95.51, 152.5 APE9-dihe-na 100.58, 175.91 APE8-dihe-in -99.71, 122.4 APE8-rot-in 297.25 APE67-dihe-in -56.22, -27.58 -36.37, -48.59 APE12-dist-in 8.393 APE11-dist-in 11.389 APE10-dist-in 5.789 APE9-dist-in 3.943 None None CSS57,CSS168 XRAY 1.85 0.201 0.232 A 276 253 8 0 0 0 [[9, 265]] 1.0 6fcf Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.2e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 6FCKA O14757 2 270 476.0 D4Z:301 Type1 Active DFGin 6.989 14.222 BLAminus -131.37, 171.79 60.5, 78.9 -94.42, 22.66 289.52, 83.51 -64.94, -20.94 in-in in 8.925 Saltbr-in 3.326 HRD-in -77.28, -47.72 71.32, 0.45 in-in-in SNCiii in-in ActLoopNT-in 3.0 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -112.05, 149.81 APE9-dihe-na 92.5, -170.86 APE8-dihe-in -92.88, 112.61 APE8-rot-in 313.22 APE67-dihe-in -64.0, -14.21 -41.55, -47.7 APE12-dist-in 8.492 APE11-dist-in 11.807 APE10-dist-in 6.351 APE9-dist-in 3.748 None None None XRAY 1.9 0.176 0.214 A 276 269 0 0 0 0 [[9, 265]] 1.0 6fck Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.2e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FSNA O14757 3 280 476.0 A58:301 Type1 Active DFGin 6.932 14.164 BLAminus -128.61, 164.88 70.43, 97.56 -103.2, 24.55 286.11, 81.86 -65.53, -27.87 in-in in 8.797 Saltbr-in 2.69 HRD-in -73.22, -47.77 74.33, -1.49 in-in-in SNCiii in-in ActLoopNT-in 2.946 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.34, 169.78 APE9-dihe-na 114.52, -151.5 APE8-dihe-in -131.96, 119.56 APE8-rot-in 303.59 APE67-dihe-in -63.31, -19.83 -39.51, -51.75 APE12-dist-in 9.012 APE11-dist-in 11.629 APE10-dist-in 6.158 APE9-dist-in 3.27 None None None XRAY 2.1 0.178 0.217 A 278 270 8 0 0 0 [[9, 265]] 1.0 4fsn Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FSMA O14757 3 280 476.0 HK1:301 Type1 Active DFGin 6.811 14.1 BLAminus -131.51, 171.53 65.39, 98.27 -106.32, 22.69 289.25, 89.34 -66.85, -29.11 in-in in 8.607 Saltbr-in 2.93 HRD-in -70.99, -49.26 75.29, 1.6 in-in-in SNCiii in-in ActLoopNT-in 2.967 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.1, 168.74 APE9-dihe-na 117.28, -151.19 APE8-dihe-in -134.15, 119.96 APE8-rot-in 302.46 APE67-dihe-in -60.14, -26.02 -38.68, -52.02 APE12-dist-in 9.051 APE11-dist-in 11.522 APE10-dist-in 5.959 APE9-dist-in 3.286 None None None XRAY 2.3 0.176 0.198 A 279 265 13 0 0 0 [[9, 265]] 1.0 4fsm Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FSRA O14757 3 280 476.0 HKC:300 Type1 Active DFGin 6.871 14.281 BLAminus -126.58, 165.61 71.14, 98.24 -108.12, 23.67 292.66, 86.79 -61.1, -36.33 in-in in 9.154 Saltbr-in 2.844 HRD-in -68.1, -45.01 72.09, -2.18 in-in-in SNCiii in-in ActLoopNT-in 2.974 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.1, 148.18 APE9-dihe-na 118.31, -163.42 APE8-dihe-in -128.11, 114.92 APE8-rot-in 300.87 APE67-dihe-in -63.19, -17.37 -35.33, -51.8 APE12-dist-in 9.392 APE11-dist-in 11.198 APE10-dist-in 5.734 APE9-dist-in 3.337 None None None XRAY 2.5 0.177 0.198 A 279 269 9 0 0 0 [[9, 265]] 1.0 4fsr Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FSWA O14757 3 280 476.0 HK6:301 Type1 Active DFGin 6.961 14.348 BLAminus -119.62, 151.67 67.77, 103.9 -105.99, 26.03 287.76, 84.88 -67.76, -25.89 in-in in 8.512 Saltbr-in 2.831 HRD-in -69.73, -47.61 75.54, -0.76 in-in-in SNCiii in-in ActLoopNT-in 2.928 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.8, 151.78 APE9-dihe-na 118.73, -158.26 APE8-dihe-in -133.6, 120.62 APE8-rot-in 303.14 APE67-dihe-in -61.67, -21.76 -43.39, -49.14 APE12-dist-in 9.169 APE11-dist-in 11.129 APE10-dist-in 5.487 APE9-dist-in 3.328 None None CSO168 XRAY 2.3 0.185 0.212 A 279 266 12 0 0 0 [[9, 265]] 1.0 4fsw Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FSYA O14757 3 280 476.0 HK7:301 Type1 Active DFGin 7.037 14.406 BLAminus -133.9, 170.9 64.36, 92.44 -102.37, 28.4 289.81, 84.88 -65.52, -30.66 in-in in 8.364 Saltbr-in 2.762 HRD-in -71.27, -49.45 77.31, 1.06 in-in-in SNCiii in-in ActLoopNT-in 3.05 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.87, 166.71 APE9-dihe-na 112.85, -162.09 APE8-dihe-in -124.8, 131.06 APE8-rot-in 295.23 APE67-dihe-in -64.56, -25.01 -56.53, -41.12 APE12-dist-in 9.077 APE11-dist-in 11.423 APE10-dist-in 6.021 APE9-dist-in 3.356 None None CSO57 XRAY 2.3 0.183 0.226 A 279 268 10 0 0 0 [[9, 265]] 1.0 4fsy Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FSZA O14757 3 280 476.0 HK8:301 Type1 Active DFGin 6.949 14.39 BLAminus -119.9, 153.43 66.34, 106.24 -107.62, 26.47 288.2, 87.05 -66.44, -34.56 in-in in 8.491 Saltbr-in 2.745 HRD-in -69.86, -48.51 74.46, 2.01 in-in-in SNCiii in-in ActLoopNT-in 3.012 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.3, 158.49 APE9-dihe-na 111.96, -155.49 APE8-dihe-in -132.22, 121.7 APE8-rot-in 308.64 APE67-dihe-in -64.81, -18.9 -40.6, -48.6 APE12-dist-in 9.243 APE11-dist-in 11.267 APE10-dist-in 5.605 APE9-dist-in 3.287 None None CSO57,CSO168 XRAY 2.3 0.175 0.22 A 279 270 8 0 0 0 [[9, 265]] 1.0 4fsz Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FT0A O14757 3 280 476.0 HK9:301 Type1 Active DFGin 6.834 14.434 BLAminus -121.3, 156.17 66.51, 99.62 -103.86, 23.38 286.77, 86.68 -67.74, -22.21 in-in in 8.618 Saltbr-in 2.753 HRD-in -71.32, -48.66 76.71, -5.7 in-in-in SNCiii in-in ActLoopNT-in 2.961 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.21, 169.55 APE9-dihe-na 114.98, -146.91 APE8-dihe-in -133.85, 119.36 APE8-rot-in 306.38 APE67-dihe-in -61.82, -22.76 -40.65, -49.73 APE12-dist-in 8.984 APE11-dist-in 11.585 APE10-dist-in 5.992 APE9-dist-in 3.394 None None None XRAY 2.3 0.174 0.203 A 279 266 8 0 0 0 [[9, 265]] 1.0 4ft0 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FT3A O14757 2 280 476.0 H1K:301 Type1 Active DFGin 6.964 14.165 BLAminus -125.83, 166.69 67.61, 100.05 -109.27, 28.0 288.45, 82.38 -68.34, -27.81 in-in in 8.589 Saltbr-in 2.771 HRD-in -69.78, -44.73 71.85, -0.6 in-in-in SNCiii in-in ActLoopNT-in 3.03 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -140.81, 154.64 APE9-dihe-na 118.96, -155.02 APE8-dihe-in -132.3, 119.16 APE8-rot-in 307.95 APE67-dihe-in -63.69, -19.94 -39.85, -50.54 APE12-dist-in 9.145 APE11-dist-in 11.182 APE10-dist-in 5.755 APE9-dist-in 3.373 None None CSO168,CSO215 XRAY 2.5 0.17 0.213 A 279 272 7 0 0 0 [[9, 265]] 1.0 4ft3 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FT5A O14757 3 280 476.0 H2K:300 Type1 Active DFGin 6.953 14.266 BLAminus -127.2, 165.87 68.8, 94.55 -104.24, 26.6 287.26, 85.38 -67.4, -28.05 in-in in 8.449 Saltbr-in 2.762 HRD-in -69.57, -47.79 77.92, -5.64 in-in-in SNCiii in-in ActLoopNT-in 2.957 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.4, 157.75 APE9-dihe-na 110.01, -155.34 APE8-dihe-in -130.07, 123.38 APE8-rot-in 305.79 APE67-dihe-in -63.14, -20.95 -44.51, -49.54 APE12-dist-in 9.238 APE11-dist-in 11.505 APE10-dist-in 5.805 APE9-dist-in 3.423 None None None XRAY 2.4 0.18 0.223 A 279 265 13 0 0 0 [[9, 265]] 1.0 4ft5 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FT7A O14757 3 280 476.0 H3K:301 Type1 Active DFGin 6.917 14.254 BLAminus -123.26, 155.01 65.6, 104.61 -106.93, 24.92 287.72, 82.64 -63.39, -27.36 in-in in 8.745 Saltbr-in 2.773 HRD-in -68.13, -44.52 71.13, 4.67 in-in-in SNCiii in-in ActLoopNT-in 2.999 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.74, 167.5 APE9-dihe-na 117.49, -151.06 APE8-dihe-in -131.37, 120.33 APE8-rot-in 307.45 APE67-dihe-in -64.01, -19.31 -40.36, -50.09 APE12-dist-in 9.056 APE11-dist-in 11.569 APE10-dist-in 6.056 APE9-dist-in 3.295 None None None XRAY 2.2 0.172 0.195 A 279 270 8 0 0 0 [[9, 265]] 1.0 4ft7 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FT9A O14757 2 280 476.0 H4K:300 Type1 Active DFGin 7.007 14.251 BLAminus -126.66, 162.85 64.17, 98.66 -102.76, 25.95 287.5, 82.94 -63.78, -29.14 in-in in 8.707 Saltbr-in 2.683 HRD-in -70.59, -46.02 71.89, 2.79 in-in-in SNCiii in-in ActLoopNT-in 3.015 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.14, 167.54 APE9-dihe-na 119.1, -145.69 APE8-dihe-in -134.13, 123.1 APE8-rot-in 304.24 APE67-dihe-in -62.3, -22.11 -43.6, -50.05 APE12-dist-in 8.945 APE11-dist-in 11.72 APE10-dist-in 6.162 APE9-dist-in 3.283 None None None XRAY 2.2 0.163 0.206 A 279 270 9 0 0 0 [[9, 265]] 1.0 4ft9 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FTAA O14757 3 280 476.0 H5K:301 Type1 Active DFGin 7.033 14.229 BLAminus -115.22, 157.1 65.07, 98.74 -104.16, 26.55 287.97, 87.34 -67.17, -28.17 in-in in 8.609 Saltbr-in 2.74 HRD-in -69.34, -47.6 75.8, -1.19 in-in-in SNCiii in-in ActLoopNT-in 2.95 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.7, 154.16 APE9-dihe-na 113.98, -159.29 APE8-dihe-in -129.33, 114.8 APE8-rot-in 303.04 APE67-dihe-in -62.29, -17.92 -34.19, -52.76 APE12-dist-in 9.19 APE11-dist-in 11.217 APE10-dist-in 5.669 APE9-dist-in 3.272 None None CSO168 XRAY 2.4 0.172 0.211 A 279 265 13 0 0 0 [[9, 265]] 1.0 4fta Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FTCA O14757 2 280 476.0 H6K:301 Type1 Active DFGin 7.007 14.217 BLAminus -124.04, 161.25 66.03, 97.49 -103.03, 25.51 288.01, 85.12 -63.04, -32.4 in-in in 8.584 Saltbr-in 2.753 HRD-in -73.06, -46.23 73.2, 0.43 in-in-in SNCiii in-in ActLoopNT-in 2.991 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.76, 151.76 APE9-dihe-na 120.55, -155.44 APE8-dihe-in -134.19, 118.99 APE8-rot-in 305.56 APE67-dihe-in -65.13, -17.34 -40.64, -50.7 APE12-dist-in 9.196 APE11-dist-in 11.308 APE10-dist-in 5.709 APE9-dist-in 3.312 None None CSO168 XRAY 2.0 0.17 0.194 A 279 267 12 0 0 0 [[9, 265]] 1.0 4ftc Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FTIA O14757 3 279 476.0 H7K:301 Type1 Active DFGin 6.938 14.265 BLAminus -131.71, 165.12 68.45, 90.85 -99.85, 27.35 288.14, 85.15 -66.83, -26.06 in-in in 8.757 Saltbr-in 2.669 HRD-in -69.83, -48.6 74.25, 0.8 in-in-in SNCiii in-in ActLoopNT-in 2.929 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.15, 166.8 APE9-dihe-na 118.02, -149.51 APE8-dihe-in -134.76, 120.08 APE8-rot-in 303.98 APE67-dihe-in -63.85, -21.57 -41.85, -47.71 APE12-dist-in 8.948 APE11-dist-in 11.514 APE10-dist-in 6.1 APE9-dist-in 3.37 None None None XRAY 2.2 0.175 0.194 A 279 270 7 0 0 0 [[9, 265]] 1.0 4fti Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FTJA O14757 3 279 476.0 H8K:301 Type1 Active DFGin 6.858 14.158 BLAminus -126.08, 172.19 64.35, 93.91 -103.12, 23.88 288.19, 87.63 -63.51, -29.53 in-in in 8.607 Saltbr-in 2.739 HRD-in -70.61, -46.43 71.78, 1.15 in-in-in SNCiii in-in ActLoopNT-in 3.007 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.56, 169.93 APE9-dihe-na 115.22, -147.36 APE8-dihe-in -135.06, 117.23 APE8-rot-in 306.8 APE67-dihe-in -63.27, -20.35 -37.52, -49.27 APE12-dist-in 9.024 APE11-dist-in 11.658 APE10-dist-in 6.163 APE9-dist-in 3.437 None None None XRAY 2.2 0.182 0.205 A 279 266 11 0 0 0 [[9, 265]] 1.0 4ftj Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FTOA O14757 3 271 476.0 3HK:301 Type1 Active DFGin 6.959 14.238 BLAminus -127.57, 164.38 64.01, 101.47 -105.82, 25.9 289.5, 84.0 -68.68, -24.99 in-in in 8.734 Saltbr-in 2.783 HRD-in -68.98, -46.7 71.08, 0.02 in-in-in SNCiii in-in ActLoopNT-in 2.978 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.78, 154.6 APE9-dihe-na 111.8, -161.39 APE8-dihe-in -129.05, 120.57 APE8-rot-in 307.69 APE67-dihe-in -63.78, -20.08 -41.73, -50.26 APE12-dist-in 9.252 APE11-dist-in 11.186 APE10-dist-in 5.713 APE9-dist-in 3.299 None None None XRAY 2.1 0.181 0.195 A 279 252 17 0 0 0 [[9, 265]] 1.0 4fto Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FTQA O14757 3 270 476.0 4HK:301 Type1 Active DFGin 6.948 14.167 BLAminus -121.37, 155.84 67.1, 99.27 -103.93, 23.74 289.44, 84.22 -64.63, -29.39 in-in in 8.644 Saltbr-in 2.729 HRD-in -73.53, -44.86 70.84, 1.85 in-in-in SNCiii in-in ActLoopNT-in 2.971 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.76, 150.17 APE9-dihe-na 119.72, -160.49 APE8-dihe-in -131.7, 116.38 APE8-rot-in 301.57 APE67-dihe-in -62.8, -20.14 -38.44, -50.62 APE12-dist-in 9.157 APE11-dist-in 11.155 APE10-dist-in 5.573 APE9-dist-in 3.312 None None CSO168 XRAY 2.0 0.186 0.22 A 279 255 13 0 0 0 [[9, 265]] 1.0 4ftq Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FTRA O14757 3 271 476.0 5HK:301 Type1 Active DFGin 6.943 14.278 BLAminus -123.21, 153.43 70.58, 95.78 -100.72, 25.84 289.71, 85.74 -70.61, -24.38 in-in in 8.442 Saltbr-in 2.79 HRD-in -69.02, -49.81 76.72, 0.2 in-in-in SNCiii in-in ActLoopNT-in 2.986 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.88, 153.77 APE9-dihe-na 114.4, -160.46 APE8-dihe-in -130.66, 117.37 APE8-rot-in 305.19 APE67-dihe-in -61.47, -21.96 -37.98, -50.68 APE12-dist-in 9.214 APE11-dist-in 11.239 APE10-dist-in 5.761 APE9-dist-in 3.341 None None None XRAY 2.25 0.174 0.214 A 279 258 11 0 0 0 [[9, 265]] 1.0 4ftr Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FTTA O14757 3 280 476.0 6HK:301 Type1 Active DFGin 6.94 14.218 BLAminus -122.83, 153.42 68.27, 105.19 -108.24, 23.4 287.92, 83.92 -66.27, -24.53 in-in in 8.543 Saltbr-in 2.745 HRD-in -71.13, -47.05 73.89, 3.88 in-in-in SNCiii in-in ActLoopNT-in 3.034 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.81, 170.65 APE9-dihe-na 115.8, -149.58 APE8-dihe-in -133.84, 119.22 APE8-rot-in 302.97 APE67-dihe-in -62.62, -20.85 -38.98, -49.57 APE12-dist-in 9.301 APE11-dist-in 11.764 APE10-dist-in 6.151 APE9-dist-in 3.3 None None None XRAY 2.3 0.173 0.215 A 279 266 12 0 0 0 [[9, 265]] 1.0 4ftt Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FTUA O14757 3 280 476.0 7HK:301 Type1 Active DFGin 7.004 14.209 BLAminus -122.0, 154.39 66.73, 96.53 -100.93, 26.02 289.18, 80.78 -66.13, -27.5 in-in in 8.572 Saltbr-in 2.735 HRD-in -67.38, -44.96 72.12, 5.18 in-in-in SNCiii in-in ActLoopNT-in 3.057 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.18, 152.58 APE9-dihe-na 115.82, -158.26 APE8-dihe-in -130.91, 118.67 APE8-rot-in 304.9 APE67-dihe-in -60.79, -23.34 -39.91, -50.93 APE12-dist-in 9.326 APE11-dist-in 11.31 APE10-dist-in 5.899 APE9-dist-in 3.324 None None None XRAY 2.1 0.191 0.21 A 279 270 8 0 0 0 [[9, 265]] 1.0 4ftu Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4GH2A O14757 3 280 476.0 HK0:301 Type1 Active DFGin 7.051 14.226 BLAminus -123.38, 153.93 69.02, 96.41 -100.38, 23.56 288.59, 84.72 -64.85, -27.37 in-in in 8.309 Saltbr-in 2.895 HRD-in -70.31, -46.53 72.01, 0.52 in-in-in SNCiii in-in ActLoopNT-in 2.96 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.99, 152.09 APE9-dihe-na 116.77, -155.33 APE8-dihe-in -133.62, 120.42 APE8-rot-in 304.79 APE67-dihe-in -64.36, -18.36 -40.72, -49.54 APE12-dist-in 9.236 APE11-dist-in 11.437 APE10-dist-in 5.983 APE9-dist-in 3.279 None None CSO168,CSO215 XRAY 2.03 0.165 0.192 A 279 268 10 0 0 0 [[9, 265]] 1.0 4gh2 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 1NVQA O14757 3 273 476.0 UCN:400 Type1 Active DFGin 7.103 14.396 BLAminus -125.86, 163.9 66.03, 91.68 -101.2, 28.08 286.61, 74.15 -67.93, -18.15 in-in in 8.517 Saltbr-in 2.873 HRD-in -72.89, -40.79 69.72, -3.58 in-in-in SNCiii in-in ActLoopNT-in 2.963 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.67, 158.23 APE9-dihe-na 121.41, -157.73 APE8-dihe-in -131.99, 117.0 APE8-rot-in 305.5 APE67-dihe-in -60.55, -25.67 -32.5, -52.91 APE12-dist-in 9.297 APE11-dist-in 11.514 APE10-dist-in 5.747 APE9-dist-in 3.379 None None None XRAY 2.0 0.206 0.234 A 289 264 7 0 0 0 [[9, 265]] 1.0 1nvq Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 1NVRA O14757 3 273 476.0 STU:400 Type1 Active DFGin 7.007 14.466 BLAminus -138.12, 170.91 63.58, 88.44 -97.82, 26.51 284.37, 82.9 -65.94, -21.37 in-in in 8.834 Saltbr-in 3.325 HRD-in -77.73, -42.26 72.42, 0.07 in-in-in SNCiii in-in ActLoopNT-in 2.892 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.96, 168.99 APE9-dihe-na 123.47, -148.6 APE8-dihe-in -135.84, 118.76 APE8-rot-in 301.9 APE67-dihe-in -60.54, -22.99 -38.52, -52.15 APE12-dist-in 8.986 APE11-dist-in 11.773 APE10-dist-in 6.22 APE9-dist-in 3.344 None None None XRAY 1.8 0.193 0.226 A 289 264 7 0 0 0 [[9, 265]] 1.0 1nvr Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 1NVSA O14757 3 273 476.0 UCM:400 Type1 Active DFGin 6.948 14.327 BLAminus -124.54, 157.02 67.79, 99.69 -105.15, 29.66 290.94, 77.78 -68.62, -19.97 in-in in 8.855 Saltbr-in 2.994 HRD-in -72.71, -44.77 71.02, 1.77 in-in-in SNCiii in-in ActLoopNT-in 2.979 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.31, 168.53 APE9-dihe-na 121.14, -147.06 APE8-dihe-in -136.26, 119.24 APE8-rot-in 304.24 APE67-dihe-in -59.99, -25.66 -37.19, -52.23 APE12-dist-in 9.001 APE11-dist-in 11.829 APE10-dist-in 6.273 APE9-dist-in 3.311 None None None XRAY 1.8 0.232 0.255 A 289 264 7 0 0 0 [[9, 265]] 1.0 1nvs Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2WMQA O14757 7 269 476.0 ZYQ:1270 Type1 Active DFGin 6.796 14.301 BLAminus -129.03, 145.77 85.94, 84.92 -97.17, 15.57 294.92, 82.28 -58.59, -22.48 in-in in 8.846 Saltbr-in 2.95 HRD-in -73.66, -48.07 79.85, -4.75 in-in-in SNCiii in-in ActLoopNT-in 2.997 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -150.83, 146.62 APE9-dihe-na 120.81, -140.09 APE8-dihe-in -140.39, 114.38 APE8-rot-in 303.0 APE67-dihe-in -66.52, -23.18 -38.86, -48.73 APE12-dist-in 9.438 APE11-dist-in 11.69 APE10-dist-in 6.292 APE9-dist-in 3.682 None None None XRAY 2.48 0.222 0.25 A 289 246 17 0 0 0 [[9, 265]] 1.0 2wmq Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2WMRA O14757 7 270 476.0 ZYR:1271 Type1 Active DFGin 6.788 14.246 BLAminus -123.65, 155.63 63.04, 103.09 -106.02, 13.15 292.74, 86.07 -58.1, -20.3 in-in in 8.801 Saltbr-in 3.087 HRD-in -72.49, -46.78 75.8, -4.43 in-in-in SNCiii in-in ActLoopNT-in 3.033 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.91, 174.03 APE9-dihe-na 103.24, -160.08 APE8-dihe-in -132.56, 126.77 APE8-rot-in 295.16 APE67-dihe-in -69.57, -25.74 -49.21, -44.24 APE12-dist-in 9.393 APE11-dist-in 11.479 APE10-dist-in 5.803 APE9-dist-in 3.312 None None None XRAY 2.43 0.211 0.26 A 289 254 10 0 0 0 [[9, 265]] 1.0 2wmr Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2WMSA O14757 7 270 476.0 ZYS:1271 Type1 Active DFGin 6.833 14.097 BLAminus -120.52, 146.54 79.14, 90.95 -98.33, 31.19 298.09, 80.64 -65.06, -38.38 in-in in 8.545 Saltbr-in 3.215 HRD-in -69.44, -50.22 83.54, -10.58 in-in-in SNCiii in-in ActLoopNT-in 2.976 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.01, 158.54 APE9-dihe-na 117.42, -150.3 APE8-dihe-in -138.73, 119.72 APE8-rot-in 292.61 APE67-dihe-in -66.29, -34.03 -39.39, -47.99 APE12-dist-in 9.422 APE11-dist-in 11.326 APE10-dist-in 5.674 APE9-dist-in 3.574 None None None XRAY 2.7 0.225 0.259 A 289 243 21 0 0 0 [[9, 265]] 1.0 2wms Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2WMTA O14757 8 270 476.0 ZYT:1271 Type1 Active DFGin 6.785 14.281 BLAminus -125.63, 146.24 75.37, 98.66 -104.06, 17.98 297.2, 81.75 -49.27, -35.19 in-in in 8.635 Saltbr-in 3.235 HRD-in -66.09, -46.05 77.82, -7.26 in-in-in SNCiii in-in ActLoopNT-in 3.003 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.87, 162.85 APE9-dihe-na 85.87, -159.47 APE8-dihe-in -114.07, 140.35 APE8-rot-in 306.26 APE67-dihe-in -62.65, -35.9 -60.11, -40.99 APE12-dist-in 9.654 APE11-dist-in 11.321 APE10-dist-in 6.292 APE9-dist-in 3.348 None None None XRAY 2.55 0.216 0.257 A 289 248 15 0 0 0 [[9, 265]] 1.0 2wmt Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2WMUA O14757 9 270 476.0 ZYU:1271 Type1 Active DFGin 6.761 14.225 BLAminus -124.58, 149.67 73.48, 98.24 -107.24, 22.24 291.36, 85.36 -63.37, -31.63 in-in in 8.708 Saltbr-in 3.267 HRD-in -66.01, -47.65 80.18, -8.04 in-in-in SNCiii in-in ActLoopNT-in 2.897 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.94, 156.42 APE9-dihe-na 115.63, -158.82 APE8-dihe-in -128.41, 142.86 APE8-rot-in 304.02 APE67-dihe-in -62.86, -36.77 -61.36, -43.1 APE12-dist-in 9.56 APE11-dist-in 11.344 APE10-dist-in 5.724 APE9-dist-in 3.622 None None None XRAY 2.6 0.232 0.261 A 289 246 16 0 0 0 [[9, 265]] 1.0 2wmu Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2WMVA O14757 7 270 476.0 ZYV:1271 Type1 Active DFGin 6.82 14.229 BLAminus -124.93, 150.62 73.24, 97.26 -104.78, 26.94 292.36, 84.42 -64.24, -27.28 in-in in 8.594 Saltbr-in 2.992 HRD-in -67.11, -46.21 78.67, -3.53 in-in-in SNCiii in-in ActLoopNT-in 3.098 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -140.54, 147.19 APE9-dihe-na 131.68, -159.35 APE8-dihe-in -132.74, 118.07 APE8-rot-in 302.64 APE67-dihe-in -64.16, -20.61 -42.4, -49.2 APE12-dist-in 9.241 APE11-dist-in 11.599 APE10-dist-in 6.167 APE9-dist-in 3.648 None None None XRAY 2.009 0.215 0.241 A 289 251 13 0 0 0 [[9, 265]] 1.0 2wmv Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2WMWA O14757 7 269 476.0 ZYW:1270 Type1 Active DFGin 6.909 14.423 BLAminus -138.43, 150.75 76.46, 89.37 -98.01, 21.58 291.28, 80.82 -54.99, -32.89 in-in in 8.443 Saltbr-in 2.967 HRD-in -68.78, -46.97 76.52, -3.86 in-in-in SNCiii in-in ActLoopNT-in 2.869 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.16, 158.72 APE9-dihe-na 118.12, -156.78 APE8-dihe-in -132.71, 131.43 APE8-rot-in 292.41 APE67-dihe-in -67.92, -22.67 -51.42, -45.51 APE12-dist-in 9.365 APE11-dist-in 11.322 APE10-dist-in 5.785 APE9-dist-in 3.46 None None None XRAY 2.43 0.23 0.25 A 289 247 16 0 0 0 [[9, 265]] 1.0 2wmw Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2WMXA O14757 7 269 476.0 ZY6:1270 Type1 Active DFGin 6.909 14.421 BLAminus -138.41, 150.78 76.37, 89.37 -97.97, 21.58 291.28, 80.83 -54.97, -32.94 in-in in 8.441 Saltbr-in 2.966 HRD-in -68.74, -47.03 76.58, -3.91 in-in-in SNCiii in-in ActLoopNT-in 2.869 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -120.46, 168.26 APE9-dihe-na 106.57, -155.31 APE8-dihe-in -139.79, 119.56 APE8-rot-in 301.17 APE67-dihe-in -67.05, -27.81 -41.76, -47.11 APE12-dist-in 9.425 APE11-dist-in 11.466 APE10-dist-in 5.846 APE9-dist-in 3.437 None None None XRAY 2.45 0.22 0.244 A 289 248 15 0 0 0 [[9, 265]] 1.0 2wmx Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2X8DA O14757 2 281 476.0 X8D:1282 Type1 Active DFGin 6.877 14.222 BLAminus -125.34, 145.96 75.16, 98.27 -103.12, 27.2 290.54, 84.91 -65.81, -25.94 in-in in 8.844 Saltbr-in 2.735 HRD-in -72.7, -49.53 78.44, 1.87 in-in-in SNCiii in-in ActLoopNT-in 2.991 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -162.58, 168.95 APE9-dihe-na 117.28, -146.64 APE8-dihe-in -140.7, 121.77 APE8-rot-in 299.91 APE67-dihe-in -64.55, -22.3 -47.16, -49.22 APE12-dist-in 8.928 APE11-dist-in 11.939 APE10-dist-in 6.34 APE9-dist-in 3.35 None None None XRAY 1.9 0.162 0.192 A 289 280 0 0 0 0 [[9, 265]] 1.0 2x8d Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2X8IA O14757 2 269 476.0 X8I:1270 Type1 Active DFGin 6.776 14.083 BLAminus -130.04, 149.82 73.34, 96.28 -103.39, 27.63 292.92, 82.96 -65.75, -24.88 in-in in 8.793 Saltbr-in 2.576 HRD-in -77.47, -44.34 72.43, -2.94 in-in-in SNCiii in-in ActLoopNT-in 2.981 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -117.06, -13.81 APE9-dihe-na -73.16, 171.96 APE8-dihe-in -80.79, 122.28 APE8-rot-in 306.49 APE67-dihe-in -61.85, -17.2 -49.93, -44.93 APE12-dist-in 8.562 APE11-dist-in 11.543 APE10-dist-in 5.779 APE9-dist-in 3.699 None None None XRAY 1.92 0.189 0.224 A 289 261 7 0 0 0 [[9, 265]] 1.0 2x8i Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2XEYA O14757 6 269 476.0 YVQ:1270 Type1 Active DFGin 6.804 14.351 BLAminus -120.46, 134.88 92.9, 102.51 -108.36, 19.57 294.43, 85.01 -58.71, -37.33 in-in in 8.628 Saltbr-in 2.76 HRD-in -66.52, -46.0 79.92, -6.26 in-in-in SNCiii in-in ActLoopNT-in 3.069 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.81, 159.95 APE9-dihe-na 131.23, -158.32 APE8-dihe-in -120.65, 138.4 APE8-rot-in 296.68 APE67-dihe-in -63.86, -44.09 -60.1, -42.19 APE12-dist-in 9.709 APE11-dist-in 11.471 APE10-dist-in 5.99 APE9-dist-in 3.662 None None None XRAY 2.7 0.222 0.266 A 289 252 12 0 0 0 [[9, 265]] 1.0 2xey Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2XEZA O14757 7 270 476.0 XEZ:1271 Type1 Active DFGin 6.917 14.25 BLAminus -133.54, 142.66 88.28, 99.32 -106.34, 26.02 290.91, 85.99 -64.69, -27.13 in-in in 8.597 Saltbr-in 3.054 HRD-in -65.08, -46.22 76.5, -0.68 in-in-in SNCiii in-in ActLoopNT-in 3.013 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.97, 168.01 APE9-dihe-na 96.0, -161.59 APE8-dihe-in -119.9, 136.16 APE8-rot-in 305.18 APE67-dihe-in -63.7, -42.45 -59.06, -41.87 APE12-dist-in 9.071 APE11-dist-in 11.462 APE10-dist-in 6.133 APE9-dist-in 3.519 None None None XRAY 2.25 0.211 0.237 A 289 249 15 0 0 0 [[9, 265]] 1.0 2xez Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2XF0A O14757 4 270 476.0 4UB:1271 Type1 Active DFGin 6.962 14.334 BLAminus -127.76, 149.31 66.74, 102.17 -107.04, 28.33 293.33, 77.96 -65.23, -24.59 in-in in 8.573 Saltbr-in 2.894 HRD-in -65.87, -48.49 79.64, -2.44 in-in-in SNCiii in-in ActLoopNT-in 3.089 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.69, -175.12 APE9-dihe-na 97.78, -156.38 APE8-dihe-in -122.87, 129.03 APE8-rot-in 303.15 APE67-dihe-in -54.36, -33.92 -44.93, -56.27 APE12-dist-in 9.385 APE11-dist-in 11.503 APE10-dist-in 6.16 APE9-dist-in 3.449 None None None XRAY 2.4 0.204 0.244 A 289 251 16 0 0 0 [[9, 265]] 1.0 2xf0 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2YDIA O14757 2 281 476.0 YDI:1282 Type1 Active DFGin 6.976 13.97 BLAminus -126.3, 150.36 77.21, 97.59 -103.07, 23.89 288.63, 85.13 -67.84, -26.49 in-in in 8.786 Saltbr-in 2.768 HRD-in -77.6, -45.08 76.82, -1.13 in-in-in SNCiii in-in ActLoopNT-in 2.977 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -162.57, 169.22 APE9-dihe-na 113.97, -148.03 APE8-dihe-in -138.83, 121.25 APE8-rot-in 303.94 APE67-dihe-in -62.29, -21.07 -47.63, -48.12 APE12-dist-in 8.918 APE11-dist-in 12.019 APE10-dist-in 6.433 APE9-dist-in 3.354 None None None XRAY 1.6 0.168 0.2 A 289 280 0 0 0 0 [[9, 265]] 1.0 2ydi Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2YM3A O14757 8 270 476.0 YM3:1271 Type1 Active DFGin 6.945 14.55 BLAminus -124.53, 145.82 77.8, 96.14 -106.02, 30.03 290.55, 85.33 -72.09, -23.02 in-in in 8.634 Saltbr-in 2.756 HRD-in -74.61, -45.33 76.04, 0.41 in-in-in SNCiii in-in ActLoopNT-in 3.017 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.51, 177.11 APE9-dihe-na 108.64, -151.07 APE8-dihe-in -133.43, 124.53 APE8-rot-in 300.4 APE67-dihe-in -62.52, -16.87 -44.07, -52.65 APE12-dist-in 9.576 APE11-dist-in 11.772 APE10-dist-in 6.288 APE9-dist-in 3.279 None None None XRAY 2.007 0.179 0.203 A 289 247 16 0 0 0 [[9, 265]] 1.0 2ym3 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2YM4A O14757 4 270 476.0 4YM:1271 Type1 Active DFGin 6.943 14.899 BLAminus -122.13, 155.72 68.31, 93.18 -103.18, 30.94 289.55, 80.73 -72.79, -19.76 in-in in 8.664 Saltbr-in 3.501 HRD-in -69.97, -47.22 81.59, -11.8 in-in-in SNCiii in-in ActLoopNT-in 3.038 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.93, 148.67 APE9-dihe-na 118.08, -148.67 APE8-dihe-in -131.7, 127.55 APE8-rot-in 303.59 APE67-dihe-in -61.62, -16.06 -47.52, -50.41 APE12-dist-in 9.702 APE11-dist-in 11.482 APE10-dist-in 5.987 APE9-dist-in 3.547 None None None XRAY 2.35 0.206 0.247 A 289 251 16 0 0 0 [[9, 265]] 1.0 2ym4 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2YM8A O14757 8 270 476.0 YM8:1271 Type1 Active DFGin 6.918 14.484 BLAminus -119.81, 160.75 69.41, 92.68 -106.25, 26.79 288.47, 85.52 -68.01, -21.81 in-in in 8.463 Saltbr-in 2.642 HRD-in -74.85, -49.07 83.35, -9.52 in-in-in SNCiii in-in ActLoopNT-in 2.933 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.5, 170.9 APE9-dihe-na 117.99, -150.41 APE8-dihe-in -140.36, 119.04 APE8-rot-in 303.38 APE67-dihe-in -63.4, -22.13 -41.5, -51.94 APE12-dist-in 9.391 APE11-dist-in 11.695 APE10-dist-in 6.202 APE9-dist-in 3.459 None None None XRAY 2.07 0.191 0.231 A 289 246 17 0 0 0 [[9, 265]] 1.0 2ym8 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4HYHA O14757 4 272 476.0 1AM:301 Type1 Active DFGin 6.906 14.218 BLAminus -128.98, 166.78 69.3, 88.21 -100.12, 24.75 289.06, 83.24 -68.3, -20.44 in-in in 9.041 Saltbr-in 2.497 HRD-in -78.56, -45.08 75.8, -4.8 in-in-in SNCiii in-in ActLoopNT-in 2.947 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.65, 153.88 APE9-dihe-na 129.07, -156.46 APE8-dihe-in -132.58, 121.58 APE8-rot-in 303.73 APE67-dihe-in -60.58, -22.44 -37.91, -54.78 APE12-dist-in 9.063 APE11-dist-in 11.335 APE10-dist-in 5.834 APE9-dist-in 3.455 None None None XRAY 1.7 0.204 0.226 A 289 263 6 0 0 0 [[9, 265]] 1.0 4hyh Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4HYIA O14757 3 274 476.0 1AO:304 Type1 Active DFGin 6.971 14.263 BLAminus -133.52, 170.26 67.21, 89.03 -100.55, 26.73 288.63, 81.95 -69.01, -20.83 in-in in 8.703 Saltbr-in 2.8 HRD-in -76.04, -45.38 76.0, -0.31 in-in-in SNCiii in-in ActLoopNT-in 2.945 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -165.36, 169.96 APE9-dihe-na 118.31, -154.09 APE8-dihe-in -134.47, 119.9 APE8-rot-in 301.58 APE67-dihe-in -63.47, -20.04 -40.17, -52.51 APE12-dist-in 8.794 APE11-dist-in 11.802 APE10-dist-in 6.333 APE9-dist-in 3.478 None None None XRAY 1.399 0.183 0.202 A 289 269 3 0 0 0 [[9, 265]] 1.0 4hyi Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 1ZLTA O14757 2 276 476.0 HYM:400 Type1 Active DFGin 6.614 13.867 BLAminus -126.38, 168.93 65.17, 92.12 -102.75, 29.34 295.7, 86.46 -65.38, -26.93 in-in in 8.567 Saltbr-in 3.001 HRD-in -74.75, -46.48 73.58, -1.97 in-in-in SNCiii in-in ActLoopNT-in 2.901 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -147.22, 155.91 APE9-dihe-na 115.18, -153.21 APE8-dihe-in -135.77, 120.73 APE8-rot-in 302.12 APE67-dihe-in -61.41, -27.81 -37.92, -49.99 APE12-dist-in 9.026 APE11-dist-in 11.822 APE10-dist-in 6.386 APE9-dist-in 3.233 None None None XRAY 1.74 0.227 0.265 A 295 272 3 0 0 0 [[9, 265]] 1.0 1zlt Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.8e-71 245.8 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2GDOA O14757 1 273 476.0 12C:298 Type1 Active DFGin 6.959 13.949 BLAminus -127.91, 159.13 71.31, 115.52 -129.98, 13.98 288.91, 76.03 -55.88, -6.97 in-in in 8.642 Saltbr-in 2.586 HRD-in -77.91, -46.29 78.14, 3.28 in-in-in SNCiii in-in ActLoopNT-in 2.935 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -164.47, 167.51 APE9-dihe-na 121.4, -118.02 APE8-dihe-in -163.54, 121.61 APE8-rot-in 299.5 APE67-dihe-in -61.0, -21.04 -40.53, -57.04 APE12-dist-in 9.394 APE11-dist-in 12.077 APE10-dist-in 6.613 APE9-dist-in 3.333 None None None XRAY 3.0 0.206 0.259 A 295 269 4 0 0 0 [[9, 265]] 1.0 2gdo Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.8e-71 245.8 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2BR1A O14757 2 276 476.0 PFP:1277 Type1 Active DFGin 6.793 14.123 BLAminus -130.59, 159.96 73.94, 93.36 -102.22, 21.99 289.33, 86.45 -62.48, -28.03 in-in in 8.999 Saltbr-in 2.892 HRD-in -73.11, -44.22 70.56, 4.17 in-in-in SNCiii in-in ActLoopNT-in 2.973 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.65, 173.48 APE9-dihe-na 118.03, -148.27 APE8-dihe-in -138.18, 120.92 APE8-rot-in 298.16 APE67-dihe-in -63.38, -22.4 -48.9, -47.72 APE12-dist-in 9.018 APE11-dist-in 11.717 APE10-dist-in 6.306 APE9-dist-in 3.471 None None None XRAY 2.0 0.163 0.226 A 297 272 3 0 0 0 [[9, 265]] 1.0 2br1 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2BRBA O14757 2 276 476.0 PFQ:1277 Type1 Active DFGin 6.777 14.206 BLAminus -124.91, 167.19 62.16, 91.6 -103.57, 28.61 293.18, 87.6 -71.38, -21.49 in-in in 8.788 Saltbr-in 3.085 HRD-in -74.34, -47.68 74.97, -0.21 in-in-in SNCiii in-in ActLoopNT-in 2.963 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -149.17, 171.97 APE9-dihe-na 115.21, -150.83 APE8-dihe-in -129.85, 123.76 APE8-rot-in 305.36 APE67-dihe-in -64.1, -22.07 -43.43, -50.05 APE12-dist-in 9.134 APE11-dist-in 11.642 APE10-dist-in 6.016 APE9-dist-in 3.293 None None None XRAY 2.1 0.243 0.272 A 297 272 3 0 0 0 [[9, 265]] 1.0 2brb Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2BRGA O14757 7 269 476.0 DFY:1270 Type1 Active DFGin 6.757 14.35 BLAminus -136.08, 139.9 86.09, 98.75 -105.44, 16.17 289.83, 90.07 -62.74, -23.98 in-in in 8.947 Saltbr-in 2.723 HRD-in -77.38, -46.1 73.52, -1.4 in-in-in SNCiii in-in ActLoopNT-in 2.888 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -164.14, 173.86 APE9-dihe-na 118.8, -153.5 APE8-dihe-in -126.63, 115.38 APE8-rot-in 292.75 APE67-dihe-in -63.0, -12.21 -42.58, -47.41 APE12-dist-in 9.002 APE11-dist-in 11.592 APE10-dist-in 6.309 APE9-dist-in 3.574 None None None XRAY 2.1 0.212 0.294 A 297 257 6 0 0 0 [[9, 265]] 1.0 2brg Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2BRHA O14757 6 271 476.0 DFW:1272 Type1 Active DFGin 6.959 14.661 BLAminus -140.73, 143.43 79.42, 92.98 -97.12, 17.45 288.86, 83.71 -48.34, -29.94 in-in in 9.146 Saltbr-in 2.704 HRD-in -78.41, -40.27 70.76, 3.5 in-in-in SNCiii in-in ActLoopNT-in 2.887 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.83, 172.27 APE9-dihe-na 128.03, -148.83 APE8-dihe-in -135.7, 117.05 APE8-rot-in 297.03 APE67-dihe-in -64.11, -20.87 -41.67, -50.92 APE12-dist-in 9.609 APE11-dist-in 11.51 APE10-dist-in 6.147 APE9-dist-in 3.48 None None None XRAY 2.1 0.183 0.257 A 297 257 9 0 0 0 [[9, 265]] 1.0 2brh Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2BRMA O14757 7 274 476.0 DFZ:1275 Type1 Active DFGin 6.84 14.038 BLAminus -135.86, 168.58 63.75, 91.55 -106.09, 29.22 295.16, 87.09 -76.07, -17.33 in-in in 8.848 Saltbr-in 2.709 HRD-in -72.25, -46.84 78.63, -1.49 in-in-in SNCiii in-in ActLoopNT-in 3.073 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.66, 173.98 APE9-dihe-na 111.72, -142.65 APE8-dihe-in -137.48, 130.31 APE8-rot-in 300.44 APE67-dihe-in -56.88, -34.55 -54.89, -47.74 APE12-dist-in 9.027 APE11-dist-in 11.79 APE10-dist-in 6.3 APE9-dist-in 3.432 None None None XRAY 2.2 0.228 0.281 A 297 263 5 0 0 0 [[9, 265]] 1.0 2brm Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2BRNA O14757 6 276 476.0 DF1:1277 Type1 Active DFGin 6.912 14.137 BLAminus -116.25, 147.52 75.05, 98.47 -108.38, 27.03 293.17, 87.0 -64.45, -36.89 in-in in 8.657 Saltbr-in 2.943 HRD-in -68.02, -45.32 74.19, 6.58 in-in-in SNCiii in-in ActLoopNT-in 2.967 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.95, 164.76 APE9-dihe-na 125.6, -149.2 APE8-dihe-in -128.12, 132.65 APE8-rot-in 303.29 APE67-dihe-in -63.75, -28.46 -56.16, -47.84 APE12-dist-in 9.268 APE11-dist-in 11.654 APE10-dist-in 6.198 APE9-dist-in 3.462 None None None XRAY 2.8 0.207 0.285 A 297 268 3 0 0 0 [[9, 265]] 1.0 2brn Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2BROA O14757 2 276 476.0 DF2:1277 Type1 Active DFGin 6.757 14.064 BLAminus -133.35, 154.27 78.19, 90.51 -99.21, 21.9 296.19, 85.72 -64.77, -25.64 in-in in 8.908 Saltbr-in 2.81 HRD-in -70.81, -47.49 77.16, 3.76 in-in-in SNCiii in-in ActLoopNT-in 2.985 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.25, 173.9 APE9-dihe-na 116.88, -150.3 APE8-dihe-in -136.74, 118.66 APE8-rot-in 294.36 APE67-dihe-in -57.57, -22.87 -44.25, -49.17 APE12-dist-in 9.937 APE11-dist-in 11.741 APE10-dist-in 6.267 APE9-dist-in 3.477 None None None XRAY 2.2 0.202 0.279 A 297 272 3 0 0 0 [[9, 265]] 1.0 2bro Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2C3JA O14757 6 270 476.0 DBQ:1271 Type1 Active DFGin 6.95 14.213 BLAminus -126.74, 163.69 80.23, 87.53 -90.31, 22.21 294.83, 82.32 -58.14, -33.43 in-in in 8.796 Saltbr-in 2.899 HRD-in -73.1, -48.96 76.11, 1.81 in-in-in SNCiii in-in ActLoopNT-in 2.882 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.88, 175.78 APE9-dihe-na 109.29, -146.39 APE8-dihe-in -139.98, 118.77 APE8-rot-in 292.58 APE67-dihe-in -63.48, -24.39 -42.88, -48.22 APE12-dist-in 9.223 APE11-dist-in 11.743 APE10-dist-in 6.236 APE9-dist-in 3.31 None None None XRAY 2.1 0.186 0.262 A 297 257 8 0 0 0 [[9, 265]] 1.0 2c3j Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2C3LA O14757 2 273 476.0 IDZ:1274 Type1 Active DFGin 6.887 14.166 BLAminus -131.41, 151.16 78.39, 98.04 -102.86, 15.22 294.33, 84.15 -49.16, -41.07 in-in in 9.023 Saltbr-in 2.703 HRD-in -80.86, -41.66 77.27, -9.64 in-in-in SNCiii in-in ActLoopNT-in 2.76 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.08, -171.58 APE9-dihe-na 93.96, -140.63 APE8-dihe-in -146.55, 106.89 APE8-rot-in 296.71 APE67-dihe-in -64.44, -18.7 -36.5, -53.88 APE12-dist-in 9.208 APE11-dist-in 11.512 APE10-dist-in 6.019 APE9-dist-in 3.39 None None None XRAY 2.35 0.189 0.279 A 297 265 7 0 0 0 [[9, 265]] 1.0 2c3l Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2CGUA O14757 6 271 476.0 3A3:1272 Type1 Active DFGin 6.823 14.1 BLAminus -124.71, 156.71 64.48, 90.01 -96.89, 19.31 292.44, 88.74 -51.64, -28.97 in-in in 8.769 Saltbr-in 2.383 HRD-in -74.29, -41.42 79.85, -2.68 in-in-in SNCiii in-in ActLoopNT-in 3.002 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.8, 178.02 APE9-dihe-na 97.6, -145.39 APE8-dihe-in -133.7, 117.92 APE8-rot-in 294.82 APE67-dihe-in -64.83, -17.81 -46.02, -48.32 APE12-dist-in 9.237 APE11-dist-in 11.48 APE10-dist-in 6.15 APE9-dist-in 3.6 None None None XRAY 2.5 0.185 0.271 A 297 263 3 0 0 0 [[9, 265]] 1.0 2cgu Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2CGVA O14757 6 272 476.0 3B3:1273 Type1 Active DFGin 6.844 14.213 BLAminus -129.68, 147.96 68.93, 97.35 -101.57, 19.74 288.82, 96.28 -56.31, -31.16 in-in in 8.847 Saltbr-in 2.428 HRD-in -68.97, -54.08 89.53, -5.53 in-in-in SNCiii in-in ActLoopNT-in 2.835 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.1, -178.57 APE9-dihe-na 98.55, -155.28 APE8-dihe-in -129.75, 111.18 APE8-rot-in 282.3 APE67-dihe-in -64.98, -23.42 -32.4, -55.02 APE12-dist-in 9.536 APE11-dist-in 11.593 APE10-dist-in 6.218 APE9-dist-in 3.444 None None None XRAY 2.6 0.183 0.256 A 297 264 3 0 0 0 [[9, 265]] 1.0 2cgv Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2CGWA O14757 6 271 476.0 3C3:1272 Type1 Active DFGin 6.888 14.132 BLAminus -126.31, 150.55 70.28, 91.55 -95.72, 25.62 291.49, 82.98 -65.61, -26.92 in-in in 8.914 Saltbr-in 2.721 HRD-in -72.1, -42.26 69.41, 5.33 in-in-in SNCiii in-in ActLoopNT-in 2.924 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.62, 178.07 APE9-dihe-na 112.61, -143.97 APE8-dihe-in -142.62, 117.73 APE8-rot-in 285.52 APE67-dihe-in -65.12, -19.5 -40.76, -49.59 APE12-dist-in 9.127 APE11-dist-in 11.614 APE10-dist-in 6.212 APE9-dist-in 3.397 None None None XRAY 2.2 0.189 0.249 A 297 262 4 0 0 0 [[9, 265]] 1.0 2cgw Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2CGXA O14757 6 273 476.0 3D3:1274 Type1 Active DFGin 6.833 14.117 BLAminus -125.86, 152.33 68.83, 92.31 -96.49, 22.24 295.74, 81.77 -68.33, -25.83 in-in in 8.865 Saltbr-in 2.506 HRD-in -77.3, -42.87 73.93, 3.29 in-in-in SNCiii in-in ActLoopNT-in 2.934 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.75, 179.04 APE9-dihe-na 103.61, -149.01 APE8-dihe-in -138.5, 119.55 APE8-rot-in 290.31 APE67-dihe-in -60.17, -27.97 -48.57, -47.19 APE12-dist-in 9.296 APE11-dist-in 11.659 APE10-dist-in 6.192 APE9-dist-in 3.328 None None None XRAY 2.2 0.191 0.258 A 297 265 3 0 0 0 [[9, 265]] 1.0 2cgx Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 3NLBA O14757 6 271 476.0 5BE:298 Type1 Active DFGin 6.824 14.2 BLAminus -124.55, 157.38 77.01, 93.93 -101.53, 21.95 294.88, 88.17 -62.88, -34.66 in-in in 8.794 Saltbr-in 2.506 HRD-in -79.47, -46.53 76.26, -3.28 in-in-in SNCiii in-in ActLoopNT-in 2.817 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.04, 155.47 APE9-dihe-na 120.15, -160.26 APE8-dihe-in -135.73, 120.95 APE8-rot-in 291.21 APE67-dihe-in -56.59, -27.5 -50.08, -48.2 APE12-dist-in 9.465 APE11-dist-in 11.54 APE10-dist-in 5.744 APE9-dist-in 3.245 None None None XRAY 1.9 0.184 0.241 A 297 261 5 0 0 0 [[9, 265]] 1.0 3nlb Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 5DLSA O14757 6 270 476.0 5CV:301 Type1 Active DFGin 6.776 14.407 BLAminus -127.94, 160.56 79.78, 85.12 -96.72, 25.68 290.3, 82.54 -70.34, -28.9 in-in in 9.245 Saltbr-in 2.667 HRD-in -77.0, -45.98 73.56, 2.81 in-in-in SNCiii in-in ActLoopNT-in 2.948 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.09, 158.49 APE9-dihe-na 127.57, -153.37 APE8-dihe-in -134.23, 121.92 APE8-rot-in 301.31 APE67-dihe-in -59.78, -21.49 -55.94, -43.97 APE12-dist-in 9.434 APE11-dist-in 11.581 APE10-dist-in 5.722 APE9-dist-in 3.526 None None None XRAY 2.15 0.168 0.222 A 297 257 8 0 0 0 [[9, 265]] 1.0 5dls Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7BKNA O14757 7 271 476.0 ADE:301 Type1 Active DFGin 6.715 13.789 BLAminus -123.22, 178.11 54.82, 98.09 -102.01, 23.12 288.04, 98.46 -58.72, -44.48 in-in in 8.457 Saltbr-in 2.721 HRD-in -80.97, -48.58 70.41, 11.52 in-in-in SNCiii in-in ActLoopNT-in 2.978 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.16, 155.63 APE9-dihe-na 150.16, -148.64 APE8-dihe-in -128.29, 117.27 APE8-rot-in 312.17 APE67-dihe-in -60.96, -21.14 -43.64, -55.99 APE12-dist-in 9.397 APE11-dist-in 11.474 APE10-dist-in 6.03 APE9-dist-in 3.709 None None None XRAY 2.74 0.212 0.28 A 297 259 6 0 0 0 [[9, 265]] 1.0 7bkn Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7BKOA O14757 7 271 476.0 TVW:301 Type1 Active DFGin 7.547 14.686 BLAminus -131.7, 142.84 75.6, 98.75 -102.17, 27.33 285.76, 86.92 -59.85, -38.14 in-in in 9.01 Saltbr-in 2.719 HRD-in -80.43, -45.24 72.06, 16.06 in-in-in SNCiii in-in ActLoopNT-in 2.931 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -177.56, 177.47 APE9-dihe-na 109.29, -153.33 APE8-dihe-in -121.47, 124.07 APE8-rot-in 300.96 APE67-dihe-in -54.02, -14.59 -49.3, -62.95 APE12-dist-in 9.072 APE11-dist-in 11.553 APE10-dist-in 6.291 APE9-dist-in 3.27 None None None XRAY 2.3 0.246 0.331 A 297 259 6 0 0 0 [[9, 265]] 1.0 7bko Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4QYEA O14757 3 280 476.0 3DL:301 Type1 Active DFGin 6.914 14.112 BLAminus -124.84, 156.69 77.9, 93.39 -103.1, 23.38 290.26, 80.26 -63.73, -29.53 in-in in 8.942 Saltbr-in 2.583 HRD-in -72.42, -47.96 79.14, 0.2 in-in-in SNCiii in-in ActLoopNT-in 2.861 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.29, 174.85 APE9-dihe-na 114.12, -149.57 APE8-dihe-in -137.26, 119.94 APE8-rot-in 299.74 APE67-dihe-in -63.28, -19.9 -43.96, -48.93 APE12-dist-in 9.079 APE11-dist-in 11.708 APE10-dist-in 6.181 APE9-dist-in 3.258 None None None XRAY 2.05 0.171 0.208 A 298 271 7 0 0 0 [[9, 265]] 1.0 4qye Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4QYFA O14757 3 280 476.0 3DV:301 Type1 Active DFGin 6.897 14.063 BLAminus -128.79, 158.9 75.16, 93.31 -103.23, 30.89 290.8, 79.05 -72.58, -24.18 in-in in 8.932 Saltbr-in 2.669 HRD-in -71.38, -49.09 76.48, 2.12 in-in-in SNCiii in-in ActLoopNT-in 2.919 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -163.94, 176.72 APE9-dihe-na 105.68, -144.7 APE8-dihe-in -142.3, 123.67 APE8-rot-in 303.25 APE67-dihe-in -64.92, -19.69 -49.83, -45.85 APE12-dist-in 8.988 APE11-dist-in 11.703 APE10-dist-in 6.2 APE9-dist-in 3.269 None None None XRAY 2.15 0.171 0.223 A 298 269 7 0 0 0 [[9, 265]] 1.0 4qyf Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4QYGA O14757 3 273 476.0 3DW:301 Type1 Active DFGin 6.729 14.232 BLAminus -130.14, 167.67 66.49, 85.89 -96.57, 24.99 292.46, 83.53 -66.91, -20.27 in-in in 8.613 Saltbr-in 2.684 HRD-in -75.2, -47.38 77.56, 1.13 in-in-in SNCiii in-in ActLoopNT-in 2.916 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.42, 169.22 APE9-dihe-na 118.09, -146.73 APE8-dihe-in -136.23, 118.9 APE8-rot-in 301.78 APE67-dihe-in -58.65, -24.95 -43.65, -51.64 APE12-dist-in 8.923 APE11-dist-in 11.779 APE10-dist-in 6.226 APE9-dist-in 3.41 None None None XRAY 1.75 0.185 0.214 A 298 264 7 0 0 0 [[9, 265]] 1.0 4qyg Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4QYGB O14757 3 273 476.0 3DW:301 Type1 Active DFGin 6.814 14.26 BLAminus -131.28, 167.96 67.6, 84.41 -94.04, 25.62 290.63, 84.63 -68.09, -18.4 in-in in 8.643 Saltbr-in 2.815 HRD-in -74.82, -46.02 77.08, 2.44 in-in-in SNCiii in-in ActLoopNT-in 2.946 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.14, 172.0 APE9-dihe-na 119.92, -148.59 APE8-dihe-in -135.99, 119.53 APE8-rot-in 301.26 APE67-dihe-in -57.64, -21.53 -47.69, -50.26 APE12-dist-in 9.249 APE11-dist-in 11.721 APE10-dist-in 6.149 APE9-dist-in 3.456 None None None XRAY 1.75 0.185 0.214 B 298 264 7 0 0 0 [[9, 265]] 1.0 4qyg Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4QYHA O14757 3 273 476.0 3DX:301 Type1 Active DFGin 6.714 13.841 BLAminus -127.62, 167.13 70.22, 81.93 -93.79, 22.64 293.4, 81.54 -68.79, -21.86 in-in in 8.418 Saltbr-in 3.126 HRD-in -75.71, -43.97 72.44, 2.65 in-in-in SNCiii in-in ActLoopNT-in 2.937 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.3, 173.48 APE9-dihe-na 109.75, -150.14 APE8-dihe-in -135.16, 119.63 APE8-rot-in 304.63 APE67-dihe-in -60.05, -24.72 -49.2, -45.16 APE12-dist-in 9.03 APE11-dist-in 11.673 APE10-dist-in 6.112 APE9-dist-in 3.398 None None None XRAY 1.9 0.199 0.235 A 298 264 7 0 0 0 [[9, 265]] 1.0 4qyh Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4QYHB O14757 3 273 476.0 3DX:301 Type1 Active DFGin 6.879 14.009 BLAminus -124.39, 169.48 67.51, 85.49 -93.96, 24.74 292.25, 85.07 -64.1, -25.79 in-in in 8.511 Saltbr-in 2.792 HRD-in -72.54, -45.81 74.0, 2.82 in-in-in SNCiii in-in ActLoopNT-in 2.878 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.18, 171.25 APE9-dihe-na 115.52, -148.64 APE8-dihe-in -137.75, 119.64 APE8-rot-in 296.85 APE67-dihe-in -60.78, -22.11 -45.63, -50.5 APE12-dist-in 9.125 APE11-dist-in 11.766 APE10-dist-in 6.176 APE9-dist-in 3.458 None None None XRAY 1.9 0.199 0.235 B 298 264 7 0 0 0 [[9, 265]] 1.0 4qyh Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4RVKA O14757 3 273 476.0 3XK:301 Type1 Active DFGin 6.786 14.085 BLAminus -129.79, 164.19 71.3, 92.68 -106.21, 24.95 283.48, 87.3 -69.95, -19.64 in-in in 8.496 Saltbr-in 2.583 HRD-in -71.05, -45.75 75.91, 1.09 in-in-in SNCiii in-in ActLoopNT-in 3.017 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.98, 171.98 APE9-dihe-na 109.08, -154.55 APE8-dihe-in -133.03, 121.44 APE8-rot-in 305.51 APE67-dihe-in -59.83, -19.94 -43.49, -53.85 APE12-dist-in 9.058 APE11-dist-in 11.837 APE10-dist-in 6.179 APE9-dist-in 3.177 None None None XRAY 1.85 0.26 0.299 A 298 264 7 0 0 0 [[9, 265]] 1.0 4rvk Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4RVLA O14757 3 273 476.0 3XL:301 Type1 Active DFGin 6.89 14.115 BLAminus -127.93, 163.2 71.68, 92.52 -100.89, 24.56 288.93, 80.66 -66.04, -26.13 in-in in 8.546 Saltbr-in 2.691 HRD-in -73.58, -46.56 74.64, 2.34 in-in-in SNCiii in-in ActLoopNT-in 2.899 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.27, 175.0 APE9-dihe-na 109.81, -150.01 APE8-dihe-in -139.94, 120.27 APE8-rot-in 300.49 APE67-dihe-in -61.11, -23.55 -46.48, -50.16 APE12-dist-in 9.112 APE11-dist-in 11.806 APE10-dist-in 6.191 APE9-dist-in 3.225 None None None XRAY 1.85 0.19 0.216 A 298 258 13 0 0 0 [[9, 265]] 1.0 4rvl Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4RVMA O14757 3 273 476.0 3X7:301 Type1 Active DFGin 6.862 14.038 BLAminus -123.09, 161.86 72.52, 87.28 -98.9, 25.75 290.38, 81.52 -65.59, -25.28 in-in in 8.499 Saltbr-in 2.659 HRD-in -75.9, -43.39 74.19, 2.07 in-in-in SNCiii in-in ActLoopNT-in 2.923 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -149.76, 173.82 APE9-dihe-na 114.14, -153.45 APE8-dihe-in -138.11, 123.56 APE8-rot-in 300.31 APE67-dihe-in -62.25, -23.64 -48.14, -48.07 APE12-dist-in 9.028 APE11-dist-in 11.724 APE10-dist-in 6.066 APE9-dist-in 3.304 None None None XRAY 1.86 0.203 0.242 A 298 264 7 0 0 0 [[9, 265]] 1.0 4rvm Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7AKOA O14757 2 271 476.0 STU:60301 Type1 Active DFGin 7.258 14.346 BLAminus -129.99, 164.38 63.12, 90.57 -95.99, 30.1 286.66, 77.28 -66.31, -26.96 in-in in 8.834 Saltbr-in 2.687 HRD-in -79.3, -45.9 76.54, 2.66 in-in-in SNCiii in-in ActLoopNT-in 2.999 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -151.15, 172.04 APE9-dihe-na 107.34, -156.22 APE8-dihe-in -136.58, 123.75 APE8-rot-in 305.71 APE67-dihe-in -59.04, -20.83 -49.6, -50.22 APE12-dist-in 8.951 APE11-dist-in 11.921 APE10-dist-in 6.385 APE9-dist-in 3.572 D10R None None XRAY 1.8 0.192 0.235 A 300 270 0 0 0 0 [[9, 265]] 1.0 7ako Homo sapiens CAMK_CHEK1_HUMAN CAMK 3.4e-71 245.5 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7AKOB O14757 2 271 476.0 STU:60301 Type1 Active DFGin 7.037 14.527 BLAminus -133.06, 166.86 60.65, 91.44 -101.1, 26.21 287.91, 78.35 -62.72, -24.94 in-in in 9.183 Saltbr-in 3.404 HRD-in -77.35, -44.25 76.09, 6.63 in-in-in SNCiii in-in ActLoopNT-in 3.039 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -146.79, 168.24 APE9-dihe-na 123.14, -149.89 APE8-dihe-in -132.89, 126.1 APE8-rot-in 304.27 APE67-dihe-in -62.82, -10.87 -52.63, -48.98 APE12-dist-in 8.63 APE11-dist-in 11.884 APE10-dist-in 6.247 APE9-dist-in 3.495 D10R None None XRAY 1.8 0.192 0.235 B 300 270 0 0 0 0 [[9, 265]] 1.0 7ako Homo sapiens CAMK_CHEK1_HUMAN CAMK 3.4e-71 245.5 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2HOGA O14757 2 280 476.0 710:324 Type1 Active DFGin 6.918 14.348 BLAminus -132.2, 167.83 69.16, 94.58 -104.9, 28.28 291.65, 77.59 -68.3, -20.83 in-in in 8.924 Saltbr-in 2.865 HRD-in -73.55, -46.39 73.44, 0.35 in-in-in SNCiii in-in ActLoopNT-in 3.026 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.82, 159.6 APE9-dihe-na 116.01, -154.6 APE8-dihe-in -136.97, 116.06 APE8-rot-in 302.9 APE67-dihe-in -59.7, -25.14 -31.53, -54.03 APE12-dist-in 9.189 APE11-dist-in 11.437 APE10-dist-in 5.925 APE9-dist-in 3.214 None None None XRAY 1.9 0.204 0.236 A 322 272 7 0 0 0 [[9, 265]] 1.0 2hog Homo sapiens CAMK_CHEK1_HUMAN CAMK 3.8e-71 245.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2HXLA O14757 2 276 476.0 422:324 Type1 Active DFGin 6.846 14.071 BLAminus -130.75, 166.76 70.33, 92.55 -103.77, 30.08 290.87, 84.03 -71.02, -25.09 in-in in 8.678 Saltbr-in 2.947 HRD-in -72.98, -44.67 70.07, 1.52 in-in-in SNCiii in-in ActLoopNT-in 2.912 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.32, 153.75 APE9-dihe-na 120.45, -160.19 APE8-dihe-in -131.74, 120.76 APE8-rot-in 304.55 APE67-dihe-in -61.62, -21.58 -33.66, -54.8 APE12-dist-in 9.16 APE11-dist-in 11.242 APE10-dist-in 5.758 APE9-dist-in 3.296 None None None XRAY 1.8 0.24 0.27 A 322 272 3 0 0 0 [[9, 265]] 1.0 2hxl Homo sapiens CAMK_CHEK1_HUMAN CAMK 3.8e-71 245.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2QHMA O14757 2 280 476.0 7CS:500 Type1 Active DFGin 6.772 14.08 BLAminus -128.04, 164.43 76.84, 101.69 -108.83, 21.45 292.71, 82.54 -63.16, -31.58 in-in in 8.975 Saltbr-in 3.022 HRD-in -76.01, -44.64 71.83, -0.16 in-in-in SNCiii in-in ActLoopNT-in 2.887 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.23, 170.83 APE9-dihe-na 117.51, -152.64 APE8-dihe-in -136.18, 123.8 APE8-rot-in 296.25 APE67-dihe-in -58.13, -21.13 -38.91, -55.77 APE12-dist-in 9.195 APE11-dist-in 11.636 APE10-dist-in 6.134 APE9-dist-in 3.16 None None None XRAY 2.0 0.195 0.237 A 323 268 11 0 0 0 [[9, 265]] 1.0 2qhm Homo sapiens CAMK_CHEK1_HUMAN CAMK 3.9e-71 245.3 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2QHNA O14757 2 280 476.0 582:500 Type1 Active DFGin 6.88 14.133 BLAminus -126.49, 161.83 70.32, 93.37 -99.87, 25.92 292.06, 80.64 -63.7, -34.99 in-in in 8.792 Saltbr-in 2.746 HRD-in -76.39, -44.4 73.61, -2.54 in-in-in SNCiii in-in ActLoopNT-in 2.92 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -140.44, 160.33 APE9-dihe-na 118.4, -157.67 APE8-dihe-in -138.42, 120.63 APE8-rot-in 297.79 APE67-dihe-in -60.96, -22.13 -36.11, -57.97 APE12-dist-in 9.21 APE11-dist-in 11.621 APE10-dist-in 5.881 APE9-dist-in 3.191 None None None XRAY 1.7 0.203 0.23 A 323 268 11 0 0 0 [[9, 265]] 1.0 2qhn Homo sapiens CAMK_CHEK1_HUMAN CAMK 3.9e-71 245.3 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2R0UA O14757 2 280 476.0 M54:324 Type1 Active DFGin 6.879 14.783 BLAminus -130.98, 175.0 63.44, 83.35 -98.83, 22.14 288.69, 85.22 -65.61, -26.86 in-in in 8.562 Saltbr-in 2.792 HRD-in -79.55, -46.26 72.28, 2.27 in-in-in SNCiii in-in ActLoopNT-in 2.924 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.26, 151.84 APE9-dihe-na 117.81, -152.92 APE8-dihe-in -133.39, 116.35 APE8-rot-in 302.77 APE67-dihe-in -61.49, -22.1 -35.67, -54.4 APE12-dist-in 9.247 APE11-dist-in 11.356 APE10-dist-in 6.137 APE9-dist-in 3.226 None None None XRAY 1.9 0.197 0.218 A 323 269 10 0 0 0 [[9, 265]] 1.0 2r0u Homo sapiens CAMK_CHEK1_HUMAN CAMK 3.9e-71 245.3 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 3TKHA O14757 2 280 476.0 07S:325 Type1 Active DFGin 7.036 14.129 BLAminus -125.51, 167.65 65.08, 90.5 -95.72, 21.17 290.82, 87.11 -61.09, -34.24 in-in in 8.501 Saltbr-in 2.814 HRD-in -73.35, -45.96 71.88, 1.74 in-in-in SNCiii in-in ActLoopNT-in 2.877 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.84, 155.22 APE9-dihe-na 115.35, -158.04 APE8-dihe-in -134.64, 120.26 APE8-rot-in 299.43 APE67-dihe-in -61.5, -21.36 -39.52, -53.35 APE12-dist-in 9.09 APE11-dist-in 11.256 APE10-dist-in 5.784 APE9-dist-in 3.223 None None None XRAY 1.79 0.184 0.201 A 323 269 10 0 0 0 [[9, 265]] 1.0 3tkh Homo sapiens CAMK_CHEK1_HUMAN CAMK 3.9e-71 245.3 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 3TKIA O14757 2 280 476.0 S25:325 Type1 Active DFGin 7.066 14.047 BLAminus -128.14, 167.81 66.79, 92.13 -100.38, 25.08 290.04, 84.3 -65.02, -26.24 in-in in 8.512 Saltbr-in 2.702 HRD-in -75.61, -43.71 71.45, -3.34 in-in-in SNCiii in-in ActLoopNT-in 2.891 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.41, 152.37 APE9-dihe-na 119.25, -155.65 APE8-dihe-in -135.42, 118.76 APE8-rot-in 302.07 APE67-dihe-in -61.44, -22.09 -36.74, -54.05 APE12-dist-in 9.235 APE11-dist-in 11.298 APE10-dist-in 5.79 APE9-dist-in 3.237 None None None XRAY 1.6 0.188 0.212 A 323 272 7 0 0 0 [[9, 265]] 1.0 3tki Homo sapiens CAMK_CHEK1_HUMAN CAMK 3.9e-71 245.3 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 5OQ5A O14757 3 270 476.0 4K4:301 Type1 Active DFGin 7.212 14.393 BLAminus -137.57, 166.94 72.85, 88.19 -97.66, 22.2 287.41, 72.48 -72.17, -15.94 in-in in 9.401 Saltbr-in 2.848 HRD-in -76.62, -42.87 75.17, -5.02 in-in-in SNCiii in-in ActLoopNT-in 2.988 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -166.87, 165.21 APE9-dihe-na 121.43, -145.46 APE8-dihe-in -135.47, 115.76 APE8-rot-in 308.05 APE67-dihe-in -59.16, -21.13 -45.59, -50.3 APE12-dist-in 9.114 APE11-dist-in 11.477 APE10-dist-in 6.308 APE9-dist-in 3.513 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A None None XRAY 1.4 0.17 0.185 A 297 265 3 0 0 0 [[9, 265]] 1.0 5oq5 Homo sapiens CAMK_CHEK1_HUMAN CAMK 1e-70 243.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 5OQ7A O14757 8 271 476.0 A0Q:301 Type1 Active DFGin 7.123 14.284 BLAminus -115.9, 149.42 83.67, 113.44 -120.56, 20.12 282.1, 87.3 -60.35, -30.28 in-in in 9.129 Saltbr-in 2.185 HRD-in -72.95, -46.31 71.63, 7.81 in-in-in SNCiii in-in ActLoopNT-in 2.954 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.79, 177.88 APE9-dihe-na 107.24, -147.89 APE8-dihe-in -133.83, 123.88 APE8-rot-in 304.96 APE67-dihe-in -60.86, -17.32 -51.61, -47.12 APE12-dist-in 9.968 APE11-dist-in 11.63 APE10-dist-in 6.087 APE9-dist-in 3.712 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A None None XRAY 2.1 0.259 0.324 A 297 259 5 0 0 0 [[9, 265]] 1.0 5oq7 Homo sapiens CAMK_CHEK1_HUMAN CAMK 1e-70 243.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 5OQ7B O14757 8 270 476.0 A0Q:301 Type1 Active DFGin 7.007 13.668 BLAminus -123.41, 144.51 76.15, 112.19 -116.09, 30.53 288.02, 74.92 -74.13, -26.43 in-in in 8.562 Saltbr-in 3.412 HRD-in -68.73, -47.06 88.33, -2.49 in-in-in SNCiii in-in ActLoopNT-in 2.963 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.0, 169.92 APE9-dihe-na 126.71, -154.19 APE8-dihe-in -137.81, 141.49 APE8-rot-in 282.73 APE67-dihe-in -51.67, -38.82 -61.07, -53.98 APE12-dist-in 9.025 APE11-dist-in 11.512 APE10-dist-in 6.116 APE9-dist-in 3.699 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A None None XRAY 2.1 0.259 0.324 B 297 256 7 0 0 0 [[9, 265]] 1.0 5oq7 Homo sapiens CAMK_CHEK1_HUMAN CAMK 1e-70 243.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FSUA O14757 4 271 476.0 HK5:301 Type1 Active DFGin 6.925 14.242 BLAminus -130.65, 164.24 65.93, 99.19 -104.79, 24.05 288.61, 85.53 -67.15, -26.86 in-in in 8.688 Saltbr-in 2.717 HRD-in -71.9, -47.68 71.19, 6.28 in-in-in SNCiii in-in ActLoopNT-in 2.993 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.25, 165.58 APE9-dihe-na 117.09, -150.06 APE8-dihe-in -133.92, 119.44 APE8-rot-in 307.97 APE67-dihe-in -62.25, -20.9 -38.55, -52.24 APE12-dist-in 9.127 APE11-dist-in 11.471 APE10-dist-in 6.003 APE9-dist-in 3.306 None None None XRAY 2.1 0.173 0.181 A 279 260 8 0 0 0 [[9, 265]] 1.0 4fsu Homo sapiens CAMK_CHEK1_HUMAN CAMK 7.2e-71 244.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 5OQ6A O14757 5 270 476.0 4K4:301 Type1 Active DFGin 6.952 13.956 BLAminus -116.27, 166.19 73.35, 97.82 -108.78, 21.61 291.33, 79.85 -70.94, -23.48 in-in in 9.39 Saltbr-in 2.768 HRD-in -76.04, -43.87 68.12, 2.56 in-in-in SNCiii in-in ActLoopNT-in 2.887 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -148.4, 175.01 APE9-dihe-na 115.83, -158.06 APE8-dihe-in -132.34, 123.75 APE8-rot-in 301.05 APE67-dihe-in -65.69, -17.68 -49.58, -46.31 APE12-dist-in 9.232 APE11-dist-in 11.239 APE10-dist-in 5.945 APE9-dist-in 3.435 A19S,Y20F,N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.95 0.16 0.192 A 297 257 9 0 0 0 [[9, 265]] 1.0 5oq6 Homo sapiens CAMK_CHEK1_HUMAN CAMK 1.8e-69 239.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 5OQ8A O14757 4 270 476.0 A0Q:301 Type1 Active DFGin 6.976 13.708 BLAminus -114.65, 171.07 70.74, 94.75 -100.36, 20.44 291.87, 83.91 -68.92, -28.4 in-in in 8.527 Saltbr-in 3.218 HRD-in -74.36, -44.04 71.63, 3.1 in-in-in SNCiii in-in ActLoopNT-in 2.982 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.21, 175.51 APE9-dihe-na 117.46, -150.37 APE8-dihe-in -131.31, 125.96 APE8-rot-in 300.85 APE67-dihe-in -65.06, -17.09 -46.84, -53.17 APE12-dist-in 8.854 APE11-dist-in 11.643 APE10-dist-in 6.306 APE9-dist-in 3.561 A19S,Y20F,N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.0 0.167 0.2 A 297 261 6 0 0 0 [[9, 265]] 1.0 5oq8 Homo sapiens CAMK_CHEK1_HUMAN CAMK 1.8e-69 239.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 9CE4A O14757 4 271 476.0 A1AV4:301 Type1 Active DFGin 7.2 13.454 BLAminus -119.78, 162.88 71.89, 104.85 -111.17, 21.45 289.63, 81.1 -64.05, -28.25 in-in in 9.118 Saltbr-in 3.069 HRD-in -74.27, -45.02 73.63, 3.4 in-in-in SNCiii in-in ActLoopNT-in 2.915 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -166.42, 168.37 APE9-dihe-na 118.29, -153.71 APE8-dihe-in -135.96, 121.9 APE8-rot-in 300.47 APE67-dihe-in -61.86, -20.64 -47.17, -48.09 APE12-dist-in 8.867 APE11-dist-in 11.566 APE10-dist-in 6.067 APE9-dist-in 3.326 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.31 0.184 0.221 A 268 258 10 0 0 0 [[9, 265]] 1.0 9ce4 Homo sapiens CAMK_CHEK1_HUMAN CAMK 3.3e-69 239.0 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 5OOTA O14757 4 270 476.0 4K4:301 Type1 Active DFGin 6.886 13.873 BLAminus -123.71, 160.5 78.56, 100.42 -111.81, 22.75 292.67, 78.9 -75.98, -17.85 in-in in 9.323 Saltbr-in 2.824 HRD-in -78.85, -47.77 75.66, -4.37 in-in-in SNCiii in-in ActLoopNT-in 2.876 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.46, 155.57 APE9-dihe-na 122.12, -167.22 APE8-dihe-in -131.08, 125.87 APE8-rot-in 298.0 APE67-dihe-in -65.3, -21.81 -53.02, -44.26 APE12-dist-in 9.155 APE11-dist-in 11.18 APE10-dist-in 5.735 APE9-dist-in 3.446 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.1 0.178 0.224 A 297 260 7 0 0 0 [[9, 265]] 1.0 5oot Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 5OP2A O14757 4 271 476.0 A0Q:301 Type1 Active DFGin 6.975 13.81 BLAminus -113.46, 163.41 77.81, 100.2 -106.41, 21.36 291.61, 81.69 -69.8, -25.56 in-in in 8.491 Saltbr-in 3.191 HRD-in -77.36, -46.21 76.3, -1.69 in-in-in SNCiii in-in ActLoopNT-in 2.915 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.61, 173.53 APE9-dihe-na 118.89, -148.19 APE8-dihe-in -135.3, 122.77 APE8-rot-in 300.97 APE67-dihe-in -69.82, -15.47 -49.44, -44.8 APE12-dist-in 9.453 APE11-dist-in 11.716 APE10-dist-in 6.284 APE9-dist-in 3.551 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.9 0.161 0.2 A 297 263 5 0 0 0 [[9, 265]] 1.0 5op2 Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 5OP4A O14757 3 270 476.0 A0T:301 Type1 Active DFGin 6.958 13.676 BLAminus -120.25, 163.52 72.52, 97.08 -105.73, 22.62 289.58, 82.01 -73.58, -24.61 in-in in 9.18 Saltbr-in 2.607 HRD-in -76.46, -44.61 73.33, 0.98 in-in-in SNCiii in-in ActLoopNT-in 2.908 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.0, 176.3 APE9-dihe-na 113.44, -150.07 APE8-dihe-in -134.9, 124.12 APE8-rot-in 296.27 APE67-dihe-in -63.53, -18.17 -48.69, -47.33 APE12-dist-in 9.066 APE11-dist-in 11.571 APE10-dist-in 6.194 APE9-dist-in 3.507 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.0 0.169 0.205 A 297 259 9 0 0 0 [[9, 265]] 1.0 5op4 Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 5OP5A O14757 4 270 476.0 3FE:301 Type1 Active DFGin 7.143 13.656 BLAminus -111.04, 162.46 74.82, 99.79 -113.07, 20.16 292.98, 78.11 -70.13, -26.75 in-in in 9.394 Saltbr-in 2.894 HRD-in -76.35, -46.93 73.16, 0.06 in-in-in SNCiii in-in ActLoopNT-in 2.881 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.71, 173.57 APE9-dihe-na 115.19, -153.36 APE8-dihe-in -133.92, 122.39 APE8-rot-in 297.32 APE67-dihe-in -67.39, -15.82 -48.27, -44.76 APE12-dist-in 8.865 APE11-dist-in 11.706 APE10-dist-in 6.215 APE9-dist-in 3.408 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.9 0.162 0.206 A 297 259 8 0 0 0 [[9, 265]] 1.0 5op5 Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 5OP7A O14757 4 270 476.0 A1K:301 Type1 Active DFGin 7.07 13.523 BLAminus -119.38, 164.65 74.16, 96.12 -105.6, 23.88 293.2, 80.09 -71.41, -20.33 in-in in 9.375 Saltbr-in 3.062 HRD-in -82.06, -43.11 72.25, 1.02 in-in-in SNCiii in-in ActLoopNT-in 2.933 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.04, 177.16 APE9-dihe-na 111.37, -152.73 APE8-dihe-in -135.08, 120.27 APE8-rot-in 299.86 APE67-dihe-in -68.14, -17.85 -45.44, -46.06 APE12-dist-in 9.049 APE11-dist-in 11.652 APE10-dist-in 6.145 APE9-dist-in 3.4 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.8 0.168 0.215 A 297 261 6 0 0 0 [[9, 265]] 1.0 5op7 Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 5OPBA O14757 5 271 476.0 A1N:301 Type1 Active DFGin 6.928 13.631 BLAminus -127.5, 170.57 73.1, 96.55 -104.05, 19.63 293.23, 83.02 -63.66, -29.12 in-in in 8.49 Saltbr-in 3.041 HRD-in -78.76, -48.56 80.79, -4.96 in-in-in SNCiii in-in ActLoopNT-in 2.957 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.16, 173.26 APE9-dihe-na 113.85, -143.9 APE8-dihe-in -134.72, 122.47 APE8-rot-in 308.74 APE67-dihe-in -59.7, -23.28 -50.86, -47.55 APE12-dist-in 9.376 APE11-dist-in 11.665 APE10-dist-in 6.233 APE9-dist-in 3.579 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.55 0.165 0.189 A 297 262 5 0 0 0 [[9, 265]] 1.0 5opb Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 5OPRA O14757 4 270 476.0 A3E:301 Type1 Active DFGin 6.957 13.557 BLAminus -118.63, 168.17 71.59, 95.55 -107.46, 21.7 291.34, 81.1 -71.92, -24.17 in-in in 9.22 Saltbr-in 2.75 HRD-in -75.64, -44.16 68.61, -1.61 in-in-in SNCiii in-in ActLoopNT-in 2.911 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.69, 179.14 APE9-dihe-na 109.46, -150.3 APE8-dihe-in -134.98, 121.9 APE8-rot-in 296.29 APE67-dihe-in -64.62, -18.13 -48.76, -45.83 APE12-dist-in 8.759 APE11-dist-in 11.804 APE10-dist-in 6.28 APE9-dist-in 3.415 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.95 0.166 0.206 A 297 258 9 0 0 0 [[9, 265]] 1.0 5opr Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 5OPSA O14757 3 270 476.0 A3Q:301 Type1 Active DFGin 6.979 13.573 BLAminus -124.54, 166.57 74.59, 94.68 -104.11, 23.06 293.13, 78.93 -70.21, -22.8 in-in in 9.235 Saltbr-in 2.889 HRD-in -76.05, -44.37 71.1, -0.07 in-in-in SNCiii in-in ActLoopNT-in 2.876 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.5, 174.02 APE9-dihe-na 119.54, -152.79 APE8-dihe-in -133.46, 124.35 APE8-rot-in 295.76 APE67-dihe-in -58.43, -25.41 -48.38, -48.15 APE12-dist-in 9.124 APE11-dist-in 11.654 APE10-dist-in 6.24 APE9-dist-in 3.516 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.0 0.163 0.202 A 297 258 10 0 0 0 [[9, 265]] 1.0 5ops Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 5OPUA O14757 3 271 476.0 A3K:301 Type1 Active DFGin 7.057 13.473 BLAminus -118.42, 161.45 74.22, 104.07 -109.02, 22.53 294.09, 83.39 -63.01, -33.06 in-in in 9.238 Saltbr-in 2.676 HRD-in -82.38, -42.44 75.35, -1.05 in-in-in SNCiii in-in ActLoopNT-in 2.919 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.28, 171.71 APE9-dihe-na 121.99, -160.54 APE8-dihe-in -131.47, 121.55 APE8-rot-in 303.24 APE67-dihe-in -61.44, -19.07 -47.23, -48.74 APE12-dist-in 9.143 APE11-dist-in 11.703 APE10-dist-in 6.177 APE9-dist-in 3.481 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.55 0.172 0.206 A 297 261 8 0 0 0 [[9, 265]] 1.0 5opu Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 5OPVA O14757 3 270 476.0 A3H:301 Type1 Active DFGin 6.96 13.606 BLAminus -121.69, 163.58 77.05, 97.9 -108.91, 21.22 289.09, 85.65 -63.92, -35.33 in-in in 9.186 Saltbr-in 2.453 HRD-in -77.36, -47.2 74.21, -3.64 in-in-in SNCiii in-in ActLoopNT-in 2.856 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.2, 172.7 APE9-dihe-na 122.38, -151.0 APE8-dihe-in -136.47, 125.7 APE8-rot-in 297.44 APE67-dihe-in -66.18, -19.24 -51.65, -45.72 APE12-dist-in 9.25 APE11-dist-in 11.717 APE10-dist-in 6.255 APE9-dist-in 3.504 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.9 0.166 0.204 A 297 261 7 0 0 0 [[9, 265]] 1.0 5opv Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7BJDA O14757 3 270 476.0 TVT:301 Type1 Active DFGin 7.084 13.659 BLAminus -125.76, 163.02 71.86, 96.41 -103.13, 21.61 289.17, 82.5 -71.88, -23.03 in-in in 8.887 Saltbr-in 2.9 HRD-in -76.23, -50.44 76.99, 0.19 in-in-in SNCiii in-in ActLoopNT-in 2.882 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.69, 177.15 APE9-dihe-na 113.59, -153.08 APE8-dihe-in -130.22, 124.06 APE8-rot-in 306.43 APE67-dihe-in -62.37, -19.5 -51.28, -48.54 APE12-dist-in 9.017 APE11-dist-in 11.599 APE10-dist-in 6.089 APE9-dist-in 3.331 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.0 0.164 0.197 A 297 263 5 0 0 0 [[9, 265]] 1.0 7bjd Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7BJEA O14757 4 270 476.0 ADE:301 Type1 Active DFGin 7.057 13.586 BLAminus -121.21, 160.63 79.82, 94.56 -105.52, 22.95 292.15, 82.58 -70.69, -20.75 in-in in 9.168 Saltbr-in 2.978 HRD-in -77.37, -47.27 75.12, 0.05 in-in-in SNCiii in-in ActLoopNT-in 2.832 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.98, 175.66 APE9-dihe-na 111.76, -150.84 APE8-dihe-in -133.41, 122.32 APE8-rot-in 300.48 APE67-dihe-in -64.02, -19.73 -50.61, -46.69 APE12-dist-in 8.933 APE11-dist-in 11.738 APE10-dist-in 6.194 APE9-dist-in 3.38 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.8 0.173 0.199 A 297 259 8 0 0 0 [[9, 265]] 1.0 7bje Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7BJHA O14757 3 270 476.0 42C:301 Type1 Active DFGin 7.039 13.667 BLAminus -116.34, 165.35 72.91, 98.36 -107.78, 21.47 288.28, 79.82 -69.94, -23.59 in-in in 9.239 Saltbr-in 2.782 HRD-in -77.33, -48.21 78.81, 0.79 in-in-in SNCiii in-in ActLoopNT-in 2.909 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.22, 175.12 APE9-dihe-na 118.78, -150.24 APE8-dihe-in -133.09, 120.06 APE8-rot-in 303.88 APE67-dihe-in -64.34, -19.53 -50.28, -45.23 APE12-dist-in 9.002 APE11-dist-in 11.736 APE10-dist-in 6.218 APE9-dist-in 3.433 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.8 0.173 0.201 A 297 260 8 0 0 0 [[9, 265]] 1.0 7bjh Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7BJJA O14757 3 270 476.0 TVW:301 Type1 Active DFGin 7.065 13.659 BLAminus -124.47, 161.87 75.65, 95.41 -106.95, 21.08 288.5, 86.21 -71.04, -20.76 in-in in 9.294 Saltbr-in 2.932 HRD-in -76.46, -47.86 74.54, -0.21 in-in-in SNCiii in-in ActLoopNT-in 2.901 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.52, 179.25 APE9-dihe-na 107.66, -150.8 APE8-dihe-in -135.65, 121.21 APE8-rot-in 299.15 APE67-dihe-in -63.43, -20.51 -51.77, -45.13 APE12-dist-in 9.114 APE11-dist-in 11.71 APE10-dist-in 6.256 APE9-dist-in 3.337 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.8 0.173 0.199 A 297 260 8 0 0 0 [[9, 265]] 1.0 7bjj Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7BJOA O14757 5 271 476.0 TWK:301 Type1 Active DFGin 7.063 13.645 BLAminus -119.72, 158.64 80.12, 94.27 -104.94, 21.07 290.11, 79.57 -69.06, -22.79 in-in in 9.503 Saltbr-in 2.64 HRD-in -81.64, -47.92 81.07, 0.87 in-in-in SNCiii in-in ActLoopNT-in 2.951 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.78, 172.47 APE9-dihe-na 110.38, -152.68 APE8-dihe-in -132.39, 122.75 APE8-rot-in 300.0 APE67-dihe-in -67.01, -18.62 -51.35, -43.85 APE12-dist-in 8.924 APE11-dist-in 11.792 APE10-dist-in 6.242 APE9-dist-in 3.469 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.3 0.165 0.207 A 297 257 10 0 0 0 [[9, 265]] 1.0 7bjo Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7BJRA O14757 5 270 476.0 TWH:301 Type1 Active DFGin 6.963 13.498 BLAminus -124.23, 160.3 73.7, 98.78 -105.4, 21.99 292.68, 81.21 -49.01, -45.76 in-in in 9.066 Saltbr-in 3.046 HRD-in -75.2, -49.25 73.18, 6.16 in-in-in SNCiii in-in ActLoopNT-in 2.859 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.32, 175.86 APE9-dihe-na 108.36, -150.65 APE8-dihe-in -133.02, 123.34 APE8-rot-in 301.05 APE67-dihe-in -62.65, -20.92 -50.03, -48.58 APE12-dist-in 8.838 APE11-dist-in 11.799 APE10-dist-in 6.257 APE9-dist-in 3.4 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.9 0.17 0.192 A 297 257 9 0 0 0 [[9, 265]] 1.0 7bjr Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7BJXA O14757 8 270 476.0 U0Q:301 Type1 Active DFGin 6.968 14.013 BLAminus -119.16, 168.61 74.53, 87.65 -98.83, 25.0 288.63, 92.62 -71.16, -25.36 in-in in 8.842 Saltbr-in 2.732 HRD-in -66.51, -58.83 81.76, -3.62 in-in-in SNCiii in-in ActLoopNT-in 2.899 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -162.31, 174.42 APE9-dihe-na 110.98, -158.13 APE8-dihe-in -122.51, 124.96 APE8-rot-in 305.1 APE67-dihe-in -66.42, -15.88 -52.33, -43.64 APE12-dist-in 8.815 APE11-dist-in 11.547 APE10-dist-in 6.103 APE9-dist-in 3.512 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.4 0.204 0.26 A 297 255 8 0 0 0 [[9, 265]] 1.0 7bjx Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7BJXB O14757 8 270 476.0 U0Q:301 Type1 Active DFGin 7.008 13.879 BLAminus -129.53, 170.8 70.69, 86.19 -101.81, 34.09 285.2, 93.96 -77.01, -26.91 in-in in 9.087 Saltbr-in 3.266 HRD-in -62.72, -54.04 75.21, -2.93 in-in-in SNCiii in-in ActLoopNT-in 2.904 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.42, 172.2 APE9-dihe-na 111.07, -153.42 APE8-dihe-in -130.98, 128.58 APE8-rot-in 299.81 APE67-dihe-in -59.32, -22.77 -56.3, -49.67 APE12-dist-in 8.587 APE11-dist-in 11.566 APE10-dist-in 6.022 APE9-dist-in 3.621 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.4 0.204 0.26 B 297 252 11 0 0 0 [[9, 265]] 1.0 7bjx Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7BK1A O14757 8 271 476.0 U0N:301 Type1 Active DFGin 6.8 13.783 BLAminus -121.8, 173.16 69.15, 89.56 -98.11, 18.64 290.94, 87.09 -66.87, -20.33 in-in in 8.546 Saltbr-in 3.38 HRD-in -76.9, -49.43 72.98, 3.48 in-in-in SNCiii in-in ActLoopNT-in 2.928 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.0, 174.77 APE9-dihe-na 112.34, -139.81 APE8-dihe-in -141.03, 122.43 APE8-rot-in 302.84 APE67-dihe-in -62.03, -22.5 -53.49, -49.69 APE12-dist-in 9.205 APE11-dist-in 11.678 APE10-dist-in 6.206 APE9-dist-in 3.494 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.0 0.192 0.235 A 297 257 7 0 0 0 [[9, 265]] 1.0 7bk1 Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7BK2A O14757 5 271 476.0 U0K:301 Type1 Active DFGin 6.89 13.774 BLAminus -124.82, 175.43 66.05, 93.67 -102.6, 23.32 290.62, 82.89 -71.81, -20.62 in-in in 8.786 Saltbr-in 3.063 HRD-in -73.35, -50.82 74.75, 4.72 in-in-in SNCiii in-in ActLoopNT-in 2.982 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.63, 173.84 APE9-dihe-na 113.99, -151.94 APE8-dihe-in -129.35, 119.79 APE8-rot-in 306.75 APE67-dihe-in -61.35, -18.19 -45.89, -53.1 APE12-dist-in 9.199 APE11-dist-in 11.66 APE10-dist-in 6.227 APE9-dist-in 3.529 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.0 0.16 0.197 A 297 261 6 0 0 0 [[9, 265]] 1.0 7bk2 Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7BK3A O14757 5 271 476.0 U0T:301 Type1 Active DFGin 6.904 13.759 BLAminus -123.18, 173.88 64.54, 96.63 -101.84, 19.24 289.62, 86.83 -69.92, -22.88 in-in in 8.744 Saltbr-in 3.063 HRD-in -77.61, -49.43 74.89, 4.0 in-in-in SNCiii in-in ActLoopNT-in 2.981 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.55, 173.32 APE9-dihe-na 112.42, -148.12 APE8-dihe-in -134.42, 118.62 APE8-rot-in 305.11 APE67-dihe-in -61.9, -17.64 -49.91, -49.05 APE12-dist-in 9.145 APE11-dist-in 11.641 APE10-dist-in 6.172 APE9-dist-in 3.561 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.0 0.173 0.225 A 297 261 6 0 0 0 [[9, 265]] 1.0 7bk3 Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7MCKA O14757 4 271 476.0 YXD:301 Type1 Active DFGin 7.091 13.493 BLAminus -116.14, 168.88 70.05, 99.13 -109.49, 22.2 291.12, 80.38 -65.63, -23.95 in-in in 9.043 Saltbr-in 2.85 HRD-in -72.23, -49.13 74.37, 1.18 in-in-in SNCiii in-in ActLoopNT-in 2.911 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.37, 168.45 APE9-dihe-na 112.73, -156.62 APE8-dihe-in -133.72, 119.69 APE8-rot-in 302.23 APE67-dihe-in -64.04, -21.06 -43.31, -48.42 APE12-dist-in 8.853 APE11-dist-in 11.364 APE10-dist-in 5.852 APE9-dist-in 3.274 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.65 0.194 0.225 A 297 263 5 0 0 0 [[9, 265]] 1.0 7mck Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7SUFA O14757 3 271 476.0 BVI:301 Type1 Active DFGin 7.129 13.724 BLAminus -103.46, 166.86 70.95, 94.53 -102.33, 19.69 289.72, 86.68 -81.72, -14.95 in-in in 8.962 Saltbr-in 2.915 HRD-in -77.79, -44.59 69.25, -2.58 in-in-in SNCiii in-in ActLoopNT-in 2.862 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.93, 167.68 APE9-dihe-na 123.94, -141.99 APE8-dihe-in -136.26, 119.39 APE8-rot-in 302.86 APE67-dihe-in -66.27, -16.33 -43.58, -49.38 APE12-dist-in 8.865 APE11-dist-in 11.886 APE10-dist-in 6.357 APE9-dist-in 3.433 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.48 0.219 0.254 A 297 262 7 0 0 0 [[9, 265]] 1.0 7suf Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7SUGA O14757 3 271 476.0 BWI:301 Type1 Active DFGin 7.129 13.724 BLAminus -103.46, 166.86 70.95, 94.53 -102.33, 19.69 289.72, 86.68 -81.72, -14.95 in-in in 8.962 Saltbr-in 2.915 HRD-in -77.79, -44.59 69.25, -2.58 in-in-in SNCiii in-in ActLoopNT-in 2.862 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.93, 167.68 APE9-dihe-na 123.94, -141.99 APE8-dihe-in -136.26, 119.39 APE8-rot-in 302.86 APE67-dihe-in -66.27, -16.33 -43.58, -49.38 APE12-dist-in 8.865 APE11-dist-in 11.886 APE10-dist-in 6.357 APE9-dist-in 3.433 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.48 0.219 0.254 A 297 262 7 0 0 0 [[9, 265]] 1.0 7sug Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7SUHA O14757 4 270 476.0 BXI:301 Type1 Active DFGin 6.978 13.326 BLAminus -119.38, 174.44 58.17, 102.88 -112.43, 21.51 291.89, 87.3 -72.91, -23.6 in-in in 8.852 Saltbr-in 3.185 HRD-in -70.43, -44.77 72.79, -5.18 in-in-in SNCiii in-in ActLoopNT-in 2.851 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.3, 155.5 APE9-dihe-na 121.03, -162.94 APE8-dihe-in -122.22, 120.31 APE8-rot-in 306.81 APE67-dihe-in -68.29, -12.17 -40.69, -51.31 APE12-dist-in 9.442 APE11-dist-in 11.601 APE10-dist-in 5.663 APE9-dist-in 3.413 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.46 0.179 0.242 A 297 261 6 0 0 0 [[9, 265]] 1.0 7suh Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7SUIA O14757 4 271 476.0 L80:301 Type1 Active DFGin 7.177 13.406 BLAminus -121.13, 166.3 71.09, 92.03 -104.59, 27.98 295.97, 86.18 -75.46, -22.7 in-in in 8.839 Saltbr-in 2.898 HRD-in -71.84, -40.65 70.78, 1.39 in-in-in SNCiii in-in ActLoopNT-in 2.88 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -167.06, 169.5 APE9-dihe-na 112.95, -154.55 APE8-dihe-in -128.22, 124.64 APE8-rot-in 306.77 APE67-dihe-in -64.51, -20.74 -44.43, -49.5 APE12-dist-in 9.043 APE11-dist-in 11.419 APE10-dist-in 6.15 APE9-dist-in 3.337 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.119 0.198 0.253 A 297 262 6 0 0 0 [[9, 265]] 1.0 7sui Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7SUJB O14757 9 271 476.0 BYL:301 Type1 Active DFGin 7.063 13.351 BLAminus -112.78, 164.5 67.33, 98.63 -107.71, 27.22 294.65, 84.19 -67.75, -27.67 in-in in 9.085 Saltbr-in 2.773 HRD-in -62.4, -45.85 74.76, 2.41 in-in-in SNCiii in-in ActLoopNT-in 3.119 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -162.97, 179.8 APE9-dihe-na 104.39, -157.62 APE8-dihe-in -121.39, 118.56 APE8-rot-in 300.57 APE67-dihe-in -61.22, -23.9 -41.31, -48.21 APE12-dist-in 9.069 APE11-dist-in 11.344 APE10-dist-in 6.076 APE9-dist-in 3.595 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.299 0.236 0.297 B 297 256 7 0 0 0 [[9, 265]] 1.0 7suj Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 8E80A O14757 8 271 476.0 UUF:301 Type1 Active DFGin 6.948 13.561 BLAminus -116.38, 163.51 69.37, 105.0 -111.89, 20.17 292.16, 81.73 -65.53, -30.68 in-in in 8.579 Saltbr-in 2.859 HRD-in -73.57, -45.75 72.69, 0.21 in-in-in SNCiii in-in ActLoopNT-in 2.949 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -163.33, 170.54 APE9-dihe-na 117.83, -149.18 APE8-dihe-in -134.92, 121.74 APE8-rot-in 303.05 APE67-dihe-in -62.91, -20.27 -44.12, -51.23 APE12-dist-in 9.365 APE11-dist-in 11.644 APE10-dist-in 6.142 APE9-dist-in 3.497 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.49 0.209 0.242 A 297 258 6 0 0 0 [[9, 265]] 1.0 8e80 Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 8E81A O14757 4 271 476.0 UU6:301 Type1 Active DFGin 6.979 13.519 BLAminus -118.37, 171.91 69.05, 96.38 -109.23, 17.13 291.1, 85.02 -68.03, -21.82 in-in in 8.54 Saltbr-in 2.811 HRD-in -71.07, -47.85 72.59, 1.56 in-in-in SNCiii in-in ActLoopNT-in 2.955 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.53, 170.33 APE9-dihe-na 117.5, -149.69 APE8-dihe-in -131.89, 120.45 APE8-rot-in 306.67 APE67-dihe-in -61.07, -20.65 -40.19, -52.75 APE12-dist-in 9.097 APE11-dist-in 11.72 APE10-dist-in 6.209 APE9-dist-in 3.5 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.62 0.202 0.232 A 297 260 8 0 0 0 [[9, 265]] 1.0 8e81 Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 8SIVA O14757 4 271 476.0 ZXH:301 Type1 Active DFGin 7.059 13.482 BLAminus -115.5, 167.7 64.71, 99.66 -107.46, 23.74 294.38, 80.14 -66.51, -23.78 in-in in 8.877 Saltbr-in 2.711 HRD-in -72.41, -42.95 71.54, 5.65 in-in-in SNCiii in-in ActLoopNT-in 2.912 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -163.84, 161.6 APE9-dihe-na 121.92, -152.74 APE8-dihe-in -132.25, 119.29 APE8-rot-in 305.39 APE67-dihe-in -62.23, -20.9 -40.75, -52.74 APE12-dist-in 9.191 APE11-dist-in 11.416 APE10-dist-in 6.076 APE9-dist-in 3.417 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.759 0.212 0.251 A 297 262 6 0 0 0 [[9, 265]] 1.0 8siv Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 8SIWA O14757 4 271 476.0 ZXL:301 Type1 Active DFGin 6.994 13.683 BLAminus -113.76, 162.62 69.21, 98.13 -108.28, 26.75 295.75, 74.32 -69.16, -23.41 in-in in 8.71 Saltbr-in 2.743 HRD-in -66.18, -44.18 72.87, 0.87 in-in-in SNCiii in-in ActLoopNT-in 2.973 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.9, 170.61 APE9-dihe-na 117.9, -150.99 APE8-dihe-in -129.35, 117.55 APE8-rot-in 300.72 APE67-dihe-in -66.83, -19.7 -40.71, -46.21 APE12-dist-in 8.819 APE11-dist-in 11.514 APE10-dist-in 6.096 APE9-dist-in 3.679 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.877 0.221 0.258 A 297 262 6 0 0 0 [[9, 265]] 1.0 8siw Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 8SIWB O14757 4 271 476.0 ZXL:301 Type1 Active DFGin 7.084 13.507 BLAminus -115.42, 169.51 62.16, 96.81 -105.7, 27.61 296.32, 77.65 -65.5, -28.47 in-in in 8.929 Saltbr-in 2.748 HRD-in -74.62, -45.0 78.8, -4.37 in-in-in SNCiii in-in ActLoopNT-in 3.04 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.18, 179.28 APE9-dihe-na 113.08, -160.42 APE8-dihe-in -127.84, 114.47 APE8-rot-in 303.7 APE67-dihe-in -63.25, -25.25 -37.36, -47.37 APE12-dist-in 9.207 APE11-dist-in 11.509 APE10-dist-in 5.964 APE9-dist-in 3.785 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.877 0.221 0.258 B 297 262 6 0 0 0 [[9, 265]] 1.0 8siw Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 8SIXA O14757 8 271 476.0 ZXP:301 Type1 Active DFGin 7.025 13.666 BLAminus -113.23, 174.49 65.61, 89.34 -102.74, 20.94 292.25, 82.21 -67.34, -24.63 in-in in 8.747 Saltbr-in 2.893 HRD-in -71.81, -44.82 73.04, 1.24 in-in-in SNCiii in-in ActLoopNT-in 2.964 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -166.47, 164.55 APE9-dihe-na 122.25, -153.58 APE8-dihe-in -132.43, 118.01 APE8-rot-in 303.52 APE67-dihe-in -63.37, -20.97 -39.74, -51.03 APE12-dist-in 8.859 APE11-dist-in 11.462 APE10-dist-in 6.15 APE9-dist-in 3.581 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.55 0.207 0.238 A 297 258 6 0 0 0 [[9, 265]] 1.0 8six Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 5F4NA O14757 5 271 476.0 5UY:301,5UY:302 Type1,Allosteric Active DFGin 6.85 14.189 BLAminus -128.01, 158.86 63.44, 104.21 -106.87, 19.19 287.19, 84.71 -57.12, -35.21 in-in in 8.538 Saltbr-in 2.765 HRD-in -66.75, -44.88 70.14, 2.2 in-in-in SNCiii in-in ActLoopNT-in 3.016 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.7, 168.71 APE9-dihe-na 117.82, -151.09 APE8-dihe-in -134.05, 123.75 APE8-rot-in 301.55 APE67-dihe-in -60.69, -34.97 -48.53, -42.54 APE12-dist-in 9.306 APE11-dist-in 11.573 APE10-dist-in 6.142 APE9-dist-in 3.384 None None None XRAY 1.91 0.151 0.188 A 273 258 9 0 0 0 [[9, 265]] 1.0 5f4n Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.1e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2YM7A O14757 7 271 476.0 YM7:1272,YM7:1273 Type1,Type1 Active DFGin 6.936 14.374 BLAminus -121.61, 152.12 75.02, 94.15 -102.21, 23.7 287.09, 83.66 -64.12, -27.24 in-in in 8.617 Saltbr-in 2.799 HRD-in -75.92, -44.81 73.37, 3.79 in-in-in SNCiii in-in ActLoopNT-in 3.002 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -149.53, 155.48 APE9-dihe-na 116.48, -155.91 APE8-dihe-in -139.15, 124.89 APE8-rot-in 299.54 APE67-dihe-in -64.41, -21.42 -48.34, -47.99 APE12-dist-in 9.246 APE11-dist-in 11.336 APE10-dist-in 6.04 APE9-dist-in 3.28 None None None XRAY 1.81 0.174 0.204 A 289 248 17 0 0 0 [[9, 265]] 1.0 2ym7 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FSTA O14757 3 270 476.0 HK4:301 Type1.5_Back Active DFGin 7.229 14.501 BLAminus -123.14, 175.81 54.94, 88.88 -99.29, 24.5 281.52, 82.61 -64.88, -24.05 in-in in 8.418 Saltbr-in 2.772 HRD-in -75.07, -48.0 73.01, 1.34 in-in-in SNCiii in-in ActLoopNT-in 2.943 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.01, 150.39 APE9-dihe-na 119.8, -156.63 APE8-dihe-in -133.38, 118.41 APE8-rot-in 301.61 APE67-dihe-in -63.43, -18.37 -42.48, -49.9 APE12-dist-in 9.187 APE11-dist-in 11.315 APE10-dist-in 5.732 APE9-dist-in 3.259 None None CSO168 XRAY 1.9 0.167 0.185 A 269 254 14 0 0 0 [[9, 265]] 1.0 4fst Homo sapiens CAMK_CHEK1_HUMAN CAMK 2e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2AYPA O14757 2 269 476.0 43A:270 Type1.5_Back Active DFGin 6.973 14.49 BLAminus -138.37, 179.8 49.32, 90.63 -98.25, 15.47 278.28, 78.06 -54.29, -32.89 in-in in 8.803 Saltbr-in 2.757 HRD-in -73.62, -38.68 66.73, -2.61 in-in-in SNCiii in-in ActLoopNT-in 2.994 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na 176.43, 157.28 APE9-dihe-na 129.59, -138.97 APE8-dihe-in -134.95, 126.35 APE8-rot-in 306.63 APE67-dihe-in -76.36, 18.56 -42.31, -52.83 APE12-dist-in 9.588 APE11-dist-in 11.831 APE10-dist-in 6.529 APE9-dist-in 3.223 None None None XRAY 2.9 0.209 0.314 A 269 268 0 0 0 0 [[9, 265]] 1.0 2ayp Homo sapiens CAMK_CHEK1_HUMAN CAMK 2e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FSQA O14757 3 280 476.0 HK3:300 Type1.5_Back Active DFGin 6.999 14.384 BLAminus -129.58, 171.1 67.76, 85.3 -96.8, 25.85 288.0, 84.66 -67.55, -27.91 in-in in 8.985 Saltbr-in 2.905 HRD-in -68.52, -48.32 74.72, 0.91 in-in-in SNCiii in-in ActLoopNT-in 2.947 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.05, 162.64 APE9-dihe-na 118.65, -156.24 APE8-dihe-in -131.59, 116.15 APE8-rot-in 306.21 APE67-dihe-in -63.38, -21.02 -38.07, -48.66 APE12-dist-in 9.125 APE11-dist-in 11.441 APE10-dist-in 5.932 APE9-dist-in 3.308 None None None XRAY 2.4 0.177 0.216 A 279 263 15 0 0 0 [[9, 265]] 1.0 4fsq Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FTKA O14757 3 280 476.0 H9K:301 Type1.5_Back Active DFGin 7.006 14.35 BLAminus -130.82, 170.32 67.66, 91.42 -102.43, 26.27 286.08, 87.58 -70.64, -27.6 in-in in 8.994 Saltbr-in 3.235 HRD-in -69.86, -48.19 74.44, -1.22 in-in-in SNCiii in-in ActLoopNT-in 3.018 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.22, 148.4 APE9-dihe-na 116.64, -159.27 APE8-dihe-in -130.65, 118.83 APE8-rot-in 306.3 APE67-dihe-in -62.59, -20.66 -41.67, -49.52 APE12-dist-in 9.226 APE11-dist-in 11.077 APE10-dist-in 5.707 APE9-dist-in 3.362 None None None XRAY 2.3 0.169 0.206 A 279 263 15 0 0 0 [[9, 265]] 1.0 4ftk Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FTMA O14757 3 280 476.0 1HK:301 Type1.5_Back Active DFGin 7.037 14.296 BLAminus -128.77, 171.8 60.97, 91.64 -99.81, 22.79 284.09, 80.44 -66.65, -24.22 in-in in 8.579 Saltbr-in 2.878 HRD-in -76.62, -47.58 73.44, 1.96 in-in-in SNCiii in-in ActLoopNT-in 2.939 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.98, 153.49 APE9-dihe-na 119.69, -162.07 APE8-dihe-in -132.76, 121.74 APE8-rot-in 303.64 APE67-dihe-in -62.56, -20.92 -44.23, -49.67 APE12-dist-in 9.165 APE11-dist-in 11.266 APE10-dist-in 5.796 APE9-dist-in 3.311 None None None XRAY 1.9 0.173 0.201 A 279 263 15 0 0 0 [[9, 265]] 1.0 4ftm Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FTNA O14757 3 271 476.0 2HK:301 Type1.5_Back Active DFGin 7.134 14.394 BLAminus -134.9, 168.86 64.32, 92.93 -102.31, 24.37 287.13, 80.28 -68.67, -25.41 in-in in 9.249 Saltbr-in 2.959 HRD-in -74.17, -47.98 73.35, 5.46 in-in-in SNCiii in-in ActLoopNT-in 2.986 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.01, 152.07 APE9-dihe-na 118.38, -157.24 APE8-dihe-in -135.4, 115.96 APE8-rot-in 302.06 APE67-dihe-in -63.78, -20.34 -42.05, -48.29 APE12-dist-in 9.139 APE11-dist-in 11.227 APE10-dist-in 5.753 APE9-dist-in 3.361 None None CSO168 XRAY 2.02 0.175 0.213 A 279 254 15 0 0 0 [[9, 265]] 1.0 4ftn Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2C3KA O14757 6 270 476.0 ABO:1271 Type1.5_Back Active DFGin 7.015 14.31 BLAminus -126.12, 172.55 61.71, 89.92 -99.46, 20.99 290.88, 86.68 -65.91, -17.18 in-in in 8.634 Saltbr-in 2.867 HRD-in -71.43, -51.73 84.39, -4.25 in-in-in SNCiii in-in ActLoopNT-in 2.771 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.82, 174.75 APE9-dihe-na 109.75, -155.16 APE8-dihe-in -124.52, 126.49 APE8-rot-in 296.43 APE67-dihe-in -70.39, -10.65 -47.18, -47.9 APE12-dist-in 9.19 APE11-dist-in 11.642 APE10-dist-in 6.119 APE9-dist-in 3.546 None None None XRAY 2.6 0.202 0.28 A 297 262 3 0 0 0 [[9, 265]] 1.0 2c3k Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 5OOPA O14757 5 271 476.0 ANP:301 ATPlike Inactive DFGin 7.048 13.858 BLAminus -117.87, 168.06 78.81, 84.96 -99.9, 22.77 292.72, 82.66 -69.65, -23.48 in-out in 9.592 Saltbr-out 3.669 HRD-in -77.29, -47.33 77.92, -0.19 out-in-in SNCoii in-in ActLoopNT-in 2.894 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.46, 169.24 APE9-dihe-na 115.98, -146.93 APE8-dihe-in -135.24, 119.66 APE8-rot-in 302.63 APE67-dihe-in -65.46, -19.69 -46.47, -46.68 APE12-dist-in 8.889 APE11-dist-in 11.835 APE10-dist-in 6.194 APE9-dist-in 3.474 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.7 0.159 0.197 A 297 261 6 0 0 0 [[9, 265]] 1.0 5oop Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 3JVSA O14757 2 272 476.0 AGY:900 Allosteric Inactive DFGin 6.928 14.214 BLAminus -125.08, 149.2 74.51, 96.16 -103.33, 29.41 288.74, 77.48 -69.19, -18.09 in-out in 8.744 Saltbr-out 3.894 HRD-in -76.21, -44.02 77.01, 0.01 out-in-in SNCoii in-in ActLoopNT-in 2.975 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.68, 173.83 APE9-dihe-na 116.0, -152.22 APE8-dihe-in -137.44, 122.36 APE8-rot-in 299.63 APE67-dihe-in -63.34, -19.96 -49.74, -47.01 APE12-dist-in 8.906 APE11-dist-in 11.826 APE10-dist-in 6.303 APE9-dist-in 3.363 None None None XRAY 1.9 0.187 0.215 A 271 256 15 0 0 0 [[9, 265]] 1.0 3jvs Homo sapiens CAMK_CHEK1_HUMAN CAMK 2e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2YM5A O14757 8 270 476.0 YM5:1271 Type1 Inactive DFGin 6.786 14.466 BLAminus -123.55, 147.23 77.25, 102.29 -108.76, 31.6 290.44, 81.79 -72.01, -24.72 in-out in 8.919 Saltbr-out 4.289 HRD-in -72.18, -44.74 74.98, -1.55 out-in-in SNCoii in-in ActLoopNT-in 2.975 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.41, 158.56 APE9-dihe-na 115.29, -154.3 APE8-dihe-in -138.66, 120.99 APE8-rot-in 298.7 APE67-dihe-in -59.21, -20.42 -44.81, -50.43 APE12-dist-in 9.454 APE11-dist-in 11.533 APE10-dist-in 5.81 APE9-dist-in 3.285 None None None XRAY 2.03 0.187 0.216 A 289 248 15 0 0 0 [[9, 265]] 1.0 2ym5 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2YM6A O14757 7 270 476.0 YM6:1271 Type1 Inactive DFGin 6.893 14.067 BLAminus -125.84, 165.3 71.75, 92.1 -105.43, 25.68 289.47, 82.42 -68.26, -25.47 in-out in 8.452 Saltbr-out 3.837 HRD-in -75.24, -45.04 77.01, -2.96 out-in-in SNCoii in-in ActLoopNT-in 2.948 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.04, 173.92 APE9-dihe-na 113.14, -153.56 APE8-dihe-in -135.04, 120.42 APE8-rot-in 305.28 APE67-dihe-in -64.72, -22.15 -41.9, -47.97 APE12-dist-in 9.392 APE11-dist-in 11.658 APE10-dist-in 6.072 APE9-dist-in 3.331 None None None XRAY 2.01 0.182 0.222 A 289 253 11 0 0 0 [[9, 265]] 1.0 2ym6 Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.6e-71 245.9 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2HXQA O14757 2 276 476.0 373:324 Type1 Inactive DFGin 6.739 14.205 BLAminus -131.67, 172.11 66.93, 93.04 -104.3, 25.93 289.41, 78.77 -64.88, -25.49 in-out in 8.872 Saltbr-out 3.653 HRD-in -75.67, -44.04 71.24, 1.14 out-in-in SNCoii in-in ActLoopNT-in 2.874 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.54, 168.7 APE9-dihe-na 121.75, -149.53 APE8-dihe-in -134.54, 121.63 APE8-rot-in 305.27 APE67-dihe-in -57.28, -30.11 -32.05, -58.28 APE12-dist-in 9.137 APE11-dist-in 11.546 APE10-dist-in 5.998 APE9-dist-in 3.286 None None None XRAY 2.0 0.23 0.26 A 322 272 3 0 0 0 [[9, 265]] 1.0 2hxq Homo sapiens CAMK_CHEK1_HUMAN CAMK 3.8e-71 245.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2HY0A O14757 2 280 476.0 306:324 Type1 Inactive DFGin 6.873 14.366 BLAminus -129.7, 171.08 67.18, 87.46 -100.9, 29.66 290.46, 79.38 -69.54, -24.68 in-out in 8.869 Saltbr-out 4.312 HRD-in -71.61, -47.13 73.77, -1.04 out-in-in SNCoii in-in ActLoopNT-in 2.998 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.22, 153.49 APE9-dihe-na 120.42, -158.94 APE8-dihe-in -133.35, 116.61 APE8-rot-in 305.54 APE67-dihe-in -62.0, -23.74 -31.71, -52.29 APE12-dist-in 9.12 APE11-dist-in 11.277 APE10-dist-in 5.784 APE9-dist-in 3.286 None None None XRAY 1.7 0.23 0.234 A 322 272 7 0 0 0 [[9, 265]] 1.0 2hy0 Homo sapiens CAMK_CHEK1_HUMAN CAMK 3.8e-71 245.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 5OORA O14757 3 283 476.0 STU:301 Type1 Inactive DFGin 7.196 13.603 BLAminus -121.08, 157.07 78.53, 94.76 -101.65, 21.08 291.71, 78.34 -70.5, -20.28 in-out in 9.325 Saltbr-out 5.381 HRD-in -78.63, -43.76 73.29, -4.94 out-in-in SNCoii in-in ActLoopNT-in 2.906 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.81, 173.83 APE9-dihe-na 115.52, -146.73 APE8-dihe-in -140.31, 116.76 APE8-rot-in 299.43 APE67-dihe-in -68.59, -17.99 -48.27, -41.97 APE12-dist-in 9.154 APE11-dist-in 11.744 APE10-dist-in 6.296 APE9-dist-in 3.597 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.9 0.167 0.208 A 297 273 8 0 0 0 [[9, 265]] 1.0 5oor Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7BJMA O14757 5 270 476.0 TW2:301 Type1 Inactive DFGin 6.951 14.027 BLAminus -115.22, 158.82 79.76, 90.94 -98.94, 22.09 292.53, 79.67 -71.79, -20.79 in-out in 9.57 Saltbr-out 3.631 HRD-in -73.21, -47.72 78.68, -2.75 out-in-in SNCoii in-in ActLoopNT-in 2.921 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -163.02, 174.96 APE9-dihe-na 106.83, -152.13 APE8-dihe-in -127.07, 123.19 APE8-rot-in 302.79 APE67-dihe-in -68.0, -22.23 -51.4, -44.18 APE12-dist-in 8.748 APE11-dist-in 11.505 APE10-dist-in 6.128 APE9-dist-in 3.592 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.3 0.178 0.231 A 297 256 10 0 0 0 [[9, 265]] 1.0 7bjm Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 7SUJA O14757 9 271 476.0 BYL:301 Type1 Inactive DFGin 6.939 13.626 BLAminus -118.6, 167.38 74.89, 93.53 -107.57, 23.59 297.11, 81.28 -67.67, -15.39 in-out in 9.057 Saltbr-out 4.109 HRD-in -70.24, -40.44 73.4, -9.88 out-in-in SNCoii in-in ActLoopNT-in 3.173 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.12, 168.37 APE9-dihe-na 116.82, -153.6 APE8-dihe-in -125.53, 126.35 APE8-rot-in 298.09 APE67-dihe-in -67.17, -13.71 -45.66, -47.75 APE12-dist-in 8.965 APE11-dist-in 11.569 APE10-dist-in 6.122 APE9-dist-in 3.731 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 2.299 0.236 0.297 A 297 256 7 0 0 0 [[9, 265]] 1.0 7suj Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 2E9NA O14757 2 270 476.0 76A:1001 Type1.5_Back Inactive DFGin 7.095 14.381 BLAminus -144.96, 155.54 84.19, 89.92 -105.99, 27.11 297.21, 81.31 -68.23, -13.23 in-out in 9.29 Saltbr-out 4.122 HRD-in -69.34, -48.43 74.18, 2.16 out-in-in SNCoii in-in ActLoopNT-in 3.164 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -164.16, 157.24 APE9-dihe-na 135.09, -139.89 APE8-dihe-in -143.44, 117.3 APE8-rot-in 325.96 APE67-dihe-in -71.39, -22.32 -31.33, -47.78 APE12-dist-in 9.444 APE11-dist-in 11.794 APE10-dist-in 6.37 APE9-dist-in 3.467 None None None XRAY 2.5 0.238 0.305 A 269 269 0 0 0 0 [[9, 265]] 1.0 2e9n Homo sapiens CAMK_CHEK1_HUMAN CAMK 2e-71 246.2 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CHK1_HUMAN 4FTLA O14757 3 280 476.0 H0K:301 Type1.5_Back Inactive DFGin 7.027 14.357 BLAminus -129.66, 168.09 67.87, 93.63 -105.0, 27.18 288.37, 90.96 -69.12, -30.84 in-out in 8.927 Saltbr-out 3.853 HRD-in -70.27, -47.56 74.38, -3.05 out-in-in SNCoii in-in ActLoopNT-in 3.067 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.74, 148.9 APE9-dihe-na 119.92, -158.25 APE8-dihe-in -131.52, 114.92 APE8-rot-in 303.17 APE67-dihe-in -66.03, -16.42 -36.91, -49.5 APE12-dist-in 9.156 APE11-dist-in 11.226 APE10-dist-in 5.738 APE9-dist-in 3.373 None None None XRAY 2.5 0.181 0.226 A 279 263 15 0 0 0 [[9, 265]] 1.0 4ftl Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.3e-71 246.1 2 256 255 147 148 149 151 153 38 55 59 127 129 128 130 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1

CAMK_CHEK1 (Serine/threonine-protein kinase Chk1)

Total number of chains: 0
Active chains: 0
Family: CAMK
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

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SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name