CMGC_CDK6 (Cyclin-dependent kinase 6)

Total number of chains: 26
Active chains: 2
Uniprot: CDK6_HUMAN
Kinase Domain Residues: 13 - 300
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 14 53.8% 1BLXA
DFGin BLAminus 7 26.9% AF-Q00534-K1A
None None 3 11.5% 1BI7A
DFGout BBAminus 2 7.7% 1G3NA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q00534-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 308 0 None None Cyclin-dependent kinase 6
AF-Q00534-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 308 0 None None Cyclin-dependent kinase 6
1JOWB 3.1 Inactive DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 10 - 300 0 None None Cyclin-dependent kinase 6
1XO2B 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoio APEdist_iiii FSE Type1 11 - 305 0 None None Cyclin-dependent kinase 6
2EUFB 3.0 Inactive DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LQQ Type1 10 - 305 0 None None Cyclin-dependent kinase 6
2F2CB 2.8 Inactive DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AP9 Type1 9 - 305 0 None None Cyclin-dependent kinase 6
4TTHB 2.9 Inactive DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 24V Type1 15 - 304 0 None None Cyclin-dependent kinase 6
1BLXA 1.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 5 - 309 0 None None Cyclin-dependent kinase 6
6OQLA 2.707 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno N1A Type1 11 - 301 0 None None Cyclin-dependent kinase 6
6OQOA 1.977 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno N1J Type1 11 - 301 0 None None Cyclin-dependent kinase 6
8I0MA 2.777 Inactive DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaiii APEdist_nnno NJ6 Type1 11 - 301 0 None None Cyclin-dependent kinase 6
3NUPA 2.6 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 3NU Type1 12 - 300 0 None None Cyclin-dependent kinase 6
3NUXA 2.7 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 3NV Type1 10 - 301 0 None None Cyclin-dependent kinase 6
4AUAA 2.31 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn 4AU Type1 11 - 301 0 None None Cyclin-dependent kinase 6
4EZ5A 2.7 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 0RS Type1 11 - 301 0 None None Cyclin-dependent kinase 6
5L2IA 2.75 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno LQQ Type1 10 - 301 0 None None Cyclin-dependent kinase 6
5L2SA 2.27 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 6ZV Type1 11 - 301 0 None None Cyclin-dependent kinase 6
5L2TA 2.37 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 6ZZ Type1 11 - 301 0 None None Cyclin-dependent kinase 6
9D8UA 2.0 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno A1AZ4 Type1 11 - 301 0 None None Cyclin-dependent kinase 6
9PE7A 2.05 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo A1CIF Type1 10 - 301 0 None E21V,K26T,T106R,Q149E Cyclin-dependent kinase 6
9PE8A 1.8 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaoii APEdist_nooo A1AZ4 Type1 10 - 301 0 None E21V,K26T,T106R,Q149E Cyclin-dependent kinase 6
1G3NA 2.9 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 9 - 301 0 None None Cyclin-dependent kinase 6
1G3NE 2.9 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 9 - 301 0 None None Cyclin-dependent kinase 6
1BI7A 3.4 Inactive None‑None none-none out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 10 - 301 0 None None Cyclin-dependent kinase 6
1BI8A 2.8 Inactive None‑None none-none out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 11 - 301 0 None None Cyclin-dependent kinase 6
1BI8C 2.8 Inactive None‑None none-none out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 11 - 301 0 None None Cyclin-dependent kinase 6

CMGC_CDK6 (Cyclin-dependent kinase 6)

Total number of chains: 26
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 14 53.8% 1BLXA
DFGin BLAminus 7 26.9% AF-Q00534-K1A
None None 3 11.5% 1BI7A
DFGout BBAminus 2 7.7% 1G3NA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CDK6_HUMAN AF-Q00534-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 308 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN AF-Q00534-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 308 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 1JOWB 3.1 Inactive DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 10 - 300 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 1XO2B 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoio APEdist_iiii FSE Type1 11 - 305 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 2EUFB 3.0 Inactive DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LQQ Type1 10 - 305 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 2F2CB 2.8 Inactive DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AP9 Type1 9 - 305 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 4TTHB 2.9 Inactive DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 24V Type1 15 - 304 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 1BLXA 1.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 5 - 309 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 6OQLA 2.707 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno N1A Type1 11 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 6OQOA 1.977 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno N1J Type1 11 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 8I0MA 2.777 Inactive DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaiii APEdist_nnno NJ6 Type1 11 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 3NUPA 2.6 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 3NU Type1 12 - 300 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 3NUXA 2.7 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 3NV Type1 10 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 4AUAA 2.31 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn 4AU Type1 11 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 4EZ5A 2.7 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 0RS Type1 11 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 5L2IA 2.75 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno LQQ Type1 10 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 5L2SA 2.27 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 6ZV Type1 11 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 5L2TA 2.37 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 6ZZ Type1 11 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 9D8UA 2.0 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno A1AZ4 Type1 11 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 9PE7A 2.05 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo A1CIF Type1 10 - 301 0 None E21V,K26T,T106R,Q149E Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 9PE8A 1.8 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaoii APEdist_nooo A1AZ4 Type1 10 - 301 0 None E21V,K26T,T106R,Q149E Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 1G3NA 2.9 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 9 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 1G3NE 2.9 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 9 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 1BI7A 3.4 Inactive None‑None none-none out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 10 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 1BI8A 2.8 Inactive None‑None none-none out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 11 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CDK6_HUMAN 1BI8C 2.8 Inactive None‑None none-none out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 11 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens

CMGC_CDK6 (Cyclin-dependent kinase 6)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism