4MXX

SRC (Proto-oncogene tyrosine-protein kinase Src)
Group: TYR
Uniprot: SRC_HUMAN
Organism: Homo sapiens
Domain boundary: 270 - 521
Resolu: 2.6

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-out in-in DB8 Type1 260 - 536 11
B Inactive DFGinter BABtrans out-out none-in DB8 Type1 261 - 536 16
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       260        270        280        290 
ghmqtqglak DAWEIPRESL RLEVKLGQGC FGEVWMGTWN 
       300        310        320        330 
GTTRVAIKTL KPGTMSPEAF LQEAQVMKKL RHEKLVQLYA 
       340        350        360        370 
VVSEEPIYIV TEYMSKGSLL DFLKGETGKY LRLPQLVDMA 
       380        390        400        410 
AQIASGMAYV ERMNYVHRDL RAANILVGEN LVCKVTDFGL 
       420        430        440        450 
arliedneyt arqgakFPIK WTAPEAALYG RFTIKSDVWS 
       460        470        480        490 
FGILLTELTT KGRVPYPGMV NREVLDQVER GYRMPCPPEC 
       500        510        520        530 
PESLHDLMCQ CWRKEPEERP TFEYLQAFLE DYFTSTEPQY 

QPGENL
Lower-case residues are disordered in structure.
Mutations: A406T
Phosphorylation: None