| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| A | Inactive | DFGout | BBAminus | in-in | out-none | B96 | Type2 | 448 - 722 | 13 |
| B | Inactive | DFGout | BBAminus | in-in | out-none | B96 | Type2 | 448 - 722 | 16 |
| C | Inactive | DFGout | BBAminus | in-in | none-none | B96 | Type2 | 448 - 722 | 17 |
| D | Inactive | DFGout | BBAminus | in-in | out-none | B96 | Type2 | 448 - 722 | 13 |
Representative sequence - Chain D
449 459 469 479
gamdrdssDD WEIPDGQITV GQRIGSGSFG TVYKGKWHGD
489 499 509 519
VAVKMLNVTA PTPQQLQAFK NEVGVLRKTR HVNILLFMGY
529 539 549 559
STKPQLAIVT QWCEGSSLYH HLHASETKFE MKKLIDIARQ
569 579 589 599
TARGMDYLHA KSIIHRDLKS NNIFLHEDNT VKIGDFGLAT
609 619 629 639
VKSrwsgshq feqlsgSILW MAPEVIRMQD SNPYSFQSDV
649 659 669 679
YAFGIVLYEL MTGQLPYSNI NNRDQIIEMV GRGSLSPDLS
689 699 709 719
KVRSNCPKRM KRLMAECLKK KRDERPSFPR ILAEIEELAR
ELSg