Ligand

Protein kinases in complex with QOP (Tovorafenib)

Total number of genes: 1

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGout	BBAminus	4	8F7OB

Database table as tsv

Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	6V34A	3.15	Inactive	DFGout	BBAminus	in-in	out-out	QOP	Type2
TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	6V34B	3.15	Inactive	DFGout	BBAminus	in-in	none-none	QOP	Type2
TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	8F7OA	3.54	Inactive	DFGout	BBAminus	in-in	out-out	QOP	Type2
TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	8F7OB	3.54	Inactive	DFGout	BBAminus	in-in	out-out	QOP	Type2

Protein kinases in complex with QOP

Total number of genes: 1

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGout	BBAminus	4	8F7OB

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
Homo sapiens	TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	6V34A	3.15	Inactive	DFGout	BBAminus	in-in	out-out	QOP	Type2
Homo sapiens	TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	6V34B	3.15	Inactive	DFGout	BBAminus	in-in	none-none	QOP	Type2
Homo sapiens	TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	8F7OA	3.54	Inactive	DFGout	BBAminus	in-in	out-out	QOP	Type2
Homo sapiens	TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	8F7OB	3.54	Inactive	DFGout	BBAminus	in-in	out-out	QOP	Type2

Protein kinases in complex with QOP

Total number of genes: 0

Total number of chains: 0

Spatial	Dihedral	Chains	Representative

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type