Ligand

Protein kinases in complex with I74 (Samuraciclib)

Total number of genes: 2

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	3	7B5OJ
None	None	1	5JQ5A

Database table as tsv

Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
CMGC	CDK2	CDK2_HUMAN	Cyclin-dependent kinase 2	5JQ5A	1.94	Inactive	None	None	out-out	out-out	I74	Type1
CMGC	CDK7	CDK7_HUMAN	Cyclin-dependent kinase 7	8P6VJ	1.9	Active	DFGin	BLAminus	in-in	in-in	I74	Type1
CMGC	CDK7	CDK7_HUMAN	Cyclin-dependent kinase 7	7B5OJ	2.5	Active	DFGin	BLAminus	in-in	in-in	I74	Type1
CMGC	CDK7	CDK7_HUMAN	Cyclin-dependent kinase 7	7B5QJ	2.5	Active	DFGin	BLAminus	in-in	in-in	I74	Type1

Protein kinases in complex with I74

Total number of genes: 2

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	3	7B5OJ
None	None	1	5JQ5A

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
Homo sapiens	CMGC	CDK2	CDK2_HUMAN	Cyclin-dependent kinase 2	5JQ5A	1.94	Inactive	None	None	out-out	out-out	I74	Type1
Homo sapiens	CMGC	CDK7	CDK7_HUMAN	Cyclin-dependent kinase 7	8P6VJ	1.9	Active	DFGin	BLAminus	in-in	in-in	I74	Type1
Homo sapiens	CMGC	CDK7	CDK7_HUMAN	Cyclin-dependent kinase 7	7B5OJ	2.5	Active	DFGin	BLAminus	in-in	in-in	I74	Type1
Homo sapiens	CMGC	CDK7	CDK7_HUMAN	Cyclin-dependent kinase 7	7B5QJ	2.5	Active	DFGin	BLAminus	in-in	in-in	I74	Type1

Protein kinases in complex with I74

Total number of genes: 0

Total number of chains: 0

Spatial	Dihedral	Chains	Representative

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type