Protein kinases in complex with D7D (Abrocitinib)

Total number of genes: 2
Total number of chains: 2
Spatial Dihedral Chains Representative
DFGin ABAminus 2 6BBVA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
TYR JAK1 JAK1_HUMAN Tyrosine-protein kinase JAK1 6BBUA 2.08 Inactive DFGin ABAminus in-in in-in D7D Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 6BBVA 1.8 Inactive DFGin ABAminus in-in in-in D7D Type1

Protein kinases in complex with D7D

Total number of genes: 2
Total number of chains: 2
Spatial Dihedral Chains Representative
DFGin ABAminus 2 6BBVA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens TYR JAK1 JAK1_HUMAN Tyrosine-protein kinase JAK1 6BBUA 2.08 Inactive DFGin ABAminus in-in in-in D7D Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 6BBVA 1.8 Inactive DFGin ABAminus in-in in-in D7D Type1

Protein kinases in complex with D7D

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type