Protein kinases in complex with 88Z (Foretinib)

Total number of genes: 3
Total number of chains: 6
Spatial Dihedral Chains Representative
DFGout BBAminus 3 6SDCA
DFGout None 3 5IA4A
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
STE STK10 STK10_HUMAN Serine/threonine-protein kinase 10 6I2YA 2.56 Inactive DFGout None out-out in-out 88Z Type2
STE STK10 STK10_HUMAN Serine/threonine-protein kinase 10 6I2YB 2.56 Inactive DFGout None out-none out-out 88Z Type2
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5IA4A 1.797 Inactive DFGout None in-out out-in 88Z Type2
TYR MET MET_HUMAN Hepatocyte growth factor receptor 6SDCA 1.67 Inactive DFGout BBAminus in-in out-in 88Z Type2
TYR MET MET_HUMAN Hepatocyte growth factor receptor 3LQ8A 2.02 Inactive DFGout BBAminus in-in out-in 88Z Type2
TYR MET MET_HUMAN Hepatocyte growth factor receptor 6SD9A 2.35 Inactive DFGout BBAminus in-in out-in 88Z Type2

Protein kinases in complex with 88Z

Total number of genes: 3
Total number of chains: 6
Spatial Dihedral Chains Representative
DFGout BBAminus 3 6SDCA
DFGout None 3 5IA4A
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens STE STK10 STK10_HUMAN Serine/threonine-protein kinase 10 6I2YA 2.56 Inactive DFGout None out-out in-out 88Z Type2
Homo sapiens STE STK10 STK10_HUMAN Serine/threonine-protein kinase 10 6I2YB 2.56 Inactive DFGout None out-none out-out 88Z Type2
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5IA4A 1.797 Inactive DFGout None in-out out-in 88Z Type2
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 6SDCA 1.67 Inactive DFGout BBAminus in-in out-in 88Z Type2
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 3LQ8A 2.02 Inactive DFGout BBAminus in-in out-in 88Z Type2
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 6SD9A 2.35 Inactive DFGout BBAminus in-in out-in 88Z Type2

Protein kinases in complex with 88Z

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type