SYK (Tyrosine-protein kinase SYK)

Group: TYR
Uniprot: KSYK_HUMAN
Domain boundary: 370 - 628


Total number of chains: 90
Spatial Dihedral Chains Representative
DFGin BLAminus 85 AF-P43405-K1A
DFGin BLBplus 3 4FL2A
DFGout BBAminus 1 3TUBA
DFGout None 1 3TUDA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-P43405-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 362 - 635 None None 0
4XG2A 2.21 Active DFGin BLAminus in-in in-in No_ligand No_ligand 364 - 635 None None 4
1XBAA 2.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 363 - 635 None None 0
4F4PA 2.37 Active DFGin BLAminus in-in in-in 0SB Type1 365 - 635 None None 0
4DFLA 1.98 Active DFGin BLAminus in-in in-in 0K0 Type1 363 - 635 None None 0
4DFNA 2.48 Active DFGin BLAminus in-in in-in 0K1 Type1 363 - 635 None None 0
4PV0A 2.0 Active DFGin BLAminus in-in in-in CG4 Type1 363 - 635 None None 0
6HM6A 2.1 Active DFGin BLAminus in-in in-in GDK Type1 364 - 632 None X525 2
6HM7A 1.64 Active DFGin BLAminus in-in in-in GDH Type1 363 - 633 None X525 3
3SRVA 1.95 Active DFGin BLAminus in-in in-in S19 Type1 364 - 634 None X525 0
3SRVB 1.95 Active DFGin BLAminus in-in in-in S19 Type1 364 - 632 None None 0
5LMAA 1.43 Active DFGin BLAminus in-in in-in 6ZG Type1 363 - 632 None X525 2
5LMBA 1.95 Active DFGin BLAminus in-in in-in 6ZF Type1 364 - 634 None X525 0
5LMBB 1.95 Active DFGin BLAminus in-in in-in 6ZF Type1 364 - 630 None X525 5
8X5KA 1.8 None DFGin BLAminus in-in in-none 3YT Type1 363 - 632 None None 5
6VOVA 1.95 Active DFGin BLAminus in-in in-in R6D Type1 363 - 629 None None 4
6VOVB 1.95 Active DFGin BLAminus in-in in-in R6D Type1 364 - 633 None None 0
4YJOA 1.6 Active DFGin BLAminus in-in in-in 4DF Type1 363 - 632 None None 3
4YJPA 1.83 Active DFGin BLAminus in-in in-in 4DL Type1 364 - 632 None None 3
4YJQA 1.34 Inactive DFGin BLAminus in-out in-in 4DK Type1 364 - 633 None X525,X526 0
4YJRA 1.32 Inactive DFGin BLAminus in-out in-in 4DJ Type1 364 - 633 None X525,X526 0
4YJSA 2.22 Active DFGin BLAminus in-in in-in 4DN Type1 364 - 632 None None 0
4YJTA 1.52 Inactive DFGin BLAminus in-out in-in 4DQ Type1 364 - 633 None X525,X526 0
4YJUA 1.67 Inactive DFGin BLAminus in-out in-in 4DO Type1 364 - 633 None X525,X526 3
4YJVA 1.652 Inactive DFGin BLAminus in-out in-in 4DT Type1 364 - 633 None X525,X526 0
5TR6A 1.93 None DFGin BLAminus in-none in-in 7KG Type1 362 - 635 None None 0
5TT7A 1.77 Active DFGin BLAminus in-in in-in 7KF Type1 358 - 635 None None 0
4RSSA 1.83 Inactive DFGin BLAminus in-in in-out 4MG Type1 364 - 634 None None 0
4XG3A 2.3 Inactive DFGin BLAminus in-out in-in X3G Type1 363 - 634 None None 0
4XG3B 2.3 Active DFGin BLAminus in-in in-in X3G Type1 363 - 633 None None 4
4XG4A 2.3 Active DFGin BLAminus in-in in-in X4G Type1 363 - 635 None None 4
4XG6A 2.4 None DFGin BLAminus in-in in-none X6G Type1 363 - 635 None None 3
4XG7A 1.76 Inactive DFGin BLAminus in-in in-out X7G Type1 364 - 635 None None 0
4XG8A 2.4 None DFGin BLAminus in-out in-none X8G Type1 366 - 635 None None 3
4XG8C 2.4 None DFGin BLAminus in-in in-none X8G Type1 364 - 629 None None 5
4XG9A 2.91 None DFGin BLAminus in-in in-none X9G Type1 363 - 632 None None 6
4XG9B 2.91 None DFGin BLAminus in-in in-none X9G Type1 363 - 634 None None 3
5GHVA 2.8 Active DFGin BLAminus in-in in-in X5G Type1 363 - 635 None None 4
5GHVB 2.8 Active DFGin BLAminus in-in in-in X5G Type1 363 - 635 None None 4
1XBBA 1.57 Active DFGin BLAminus in-in in-in STI Type1 363 - 635 None None 4
1XBCA 2.0 Active DFGin BLAminus in-in in-in STU Type1 363 - 635 None None 0
3FQEA 2.5 Active DFGin BLAminus in-in in-in P5C Type1 363 - 635 None None 3
3FQHA 2.26 Active DFGin BLAminus in-in in-in 057 Type1 363 - 634 None None 0
3FQHB 2.26 Active DFGin BLAminus in-in in-in 057 Type1 363 - 633 None None 4
3FQSA 2.1 Active DFGin BLAminus in-in in-in 585 Type1 363 - 635 None None 4
4FL1A 1.79 Active DFGin BLAminus in-in in-in ANP Type1 363 - 635 None None 0
4FYNA 2.318 Active DFGin BLAminus in-in in-in 0VE Type1 363 - 635 None None 4
4FYOA 1.4 Active DFGin BLAminus in-in in-in 0VF Type1 363 - 635 None None 4
4FZ6A 1.85 Active DFGin BLAminus in-in in-in 0VG Type1 363 - 635 None None 4
4FZ7A 1.75 Active DFGin BLAminus in-in in-in 0VH Type1 363 - 635 None None 4
4GFGA 2.35 Active DFGin BLAminus in-in in-in 0XF Type1 363 - 635 None None 0
4I0RA 2.1 Active DFGin BLAminus in-in in-in 1B4 Type1 363 - 635 None None 4
4I0SA 1.98 Active DFGin BLAminus in-in in-in 1B5 Type1 363 - 635 None None 4
4I0TA 1.7 Inactive DFGin BLAminus in-in in-out 1B6 Type1 363 - 635 None None 5
4PUZA 2.085 Active DFGin BLAminus in-in in-in CG9 Type1 363 - 633 None None 3
4PUZB 2.085 Active DFGin BLAminus in-in in-in CG9 Type1 363 - 635 None None 3
5T68A 2.93 Active DFGin BLAminus in-in in-in 77V Type1 363 - 635 None None 4
5T68B 2.93 Active DFGin BLAminus in-in in-in 77V Type1 363 - 635 None None 4
5TIUA 1.49 Active DFGin BLAminus in-in in-in 7CU Type1 363 - 635 None None 0
3EMGA 2.6 Inactive DFGin BLAminus in-out in-in 685 Type1 365 - 631 None None 4
5Y5TA 1.8 Active DFGin BLAminus in-in in-in 8OR Type1 363 - 635 None None 0
5Y5UA 2.14 Active DFGin BLAminus in-in in-in 8OU Type1 364 - 634 None None 0
5Y5UB 2.14 None DFGin BLAminus in-in in-none 8OU Type1 363 - 629 None None 6
3VF8A 2.08 None DFGin BLAminus in-none in-in 0JE Type1 363 - 635 None None 0
3VF9A 2.3 None DFGin BLAminus in-none in-in 477 Type1 364 - 635 None None 0
4WNMA 2.5 Active DFGin BLAminus in-in in-in 3RT Type1 347 - 635 None None 0
5C26A 1.95 Active DFGin BLAminus in-in in-in 50H Type1 363 - 635 None X525,X526 0
5C27A 2.15 Active DFGin BLAminus in-in in-in 50J Type1 363 - 635 None X525,X526 0
6SSBA 2.08 Active DFGin BLAminus in-in in-in LUE Type1 363 - 635 None None 1
6ZC0A 1.97 Active DFGin BLAminus in-in in-in QDZ Type1 363 - 635 None None 0
6ZCPA 2.2 Active DFGin BLAminus in-in in-in QFK Type1 363 - 635 None None 0
6ZCQA 2.32 Active DFGin BLAminus in-in in-in QFB Type1 363 - 635 None None 1
6ZCRA 1.73 Active DFGin BLAminus in-in in-in 5JG Type1 363 - 635 None None 4
6ZCSA 1.47 Active DFGin BLAminus in-in in-in QFE Type1 363 - 635 None None 1
6ZCUA 1.73 Active DFGin BLAminus in-in in-in 5JG Type1 363 - 635 None None 4
6ZCXA 1.66 Active DFGin BLAminus in-in in-in QFQ Type1 363 - 635 None None 1
6ZCYA 1.81 Active DFGin BLAminus in-in in-in QF8 Type1 363 - 635 None None 1
8BI2A 1.508 Active DFGin BLAminus in-in in-in QR7 Type1 363 - 635 None None 1
4RX7A 1.8 Active DFGin BLAminus in-in in-in 3YV Type1 363 - 635 None None 0
4RX8A 1.59 Active DFGin BLAminus in-in in-in 3YX Type1 364 - 635 None None 1
5CXHA 1.9 Active DFGin BLAminus in-in in-in 55M Type1 363 - 635 K467T None 0
5CXZA 1.7 Active DFGin BLAminus in-in in-in 55U Type1 363 - 635 K467T None 1
4RX9A 1.75 Active DFGin BLAminus in-in in-in 3YT Type1 363 - 635 None None 1
4PX6A 1.6 Active DFGin BLAminus in-in in-in 2X6 Type1 364 - 635 K467T None 4
5CY3A 1.76 Active DFGin BLAminus in-in in-in 55Y Type1 360 - 635 K467T None 0
4FL3A 1.9 Inactive DFGin BLBplus out-out out-none ANP Type1 9 - 635 Y348F,Y352F None 13
4FL2A 2.19 Inactive DFGin BLBplus out-out out-out ANP Type1 9 - 635 None None 0
3TUCA 2.1 Inactive DFGin BLBplus out-out none-none FPW Type1.5_Front 358 - 633 None None 19
3TUBA 2.23 Inactive DFGout BBAminus in-out none-none FPU Type2 362 - 633 None None 19
3TUDA 2.33 Inactive DFGout None in-in none-in FPX Type2 363 - 635 None None 18

SYK (Tyrosine-protein kinase SYK)

Group: TYR
Total number of chains: 90
Spatial Dihedral Chains Representative
DFGin BLAminus 85 AF-P43405-K1A
DFGin BLBplus 3 4FL2A
DFGout BBAminus 1 3TUBA
DFGout None 1 3TUDA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens KSYK_HUMAN AF-P43405-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 362 - 635 None None 0
Homo sapiens KSYK_HUMAN 4XG2A 2.21 Active DFGin BLAminus in-in in-in No_ligand No_ligand 364 - 635 None None 4
Homo sapiens KSYK_HUMAN 1XBAA 2.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 363 - 635 None None 0
Homo sapiens KSYK_HUMAN 4F4PA 2.37 Active DFGin BLAminus in-in in-in 0SB Type1 365 - 635 None None 0
Homo sapiens KSYK_HUMAN 4DFLA 1.98 Active DFGin BLAminus in-in in-in 0K0 Type1 363 - 635 None None 0
Homo sapiens KSYK_HUMAN 4DFNA 2.48 Active DFGin BLAminus in-in in-in 0K1 Type1 363 - 635 None None 0
Homo sapiens KSYK_HUMAN 4PV0A 2.0 Active DFGin BLAminus in-in in-in CG4 Type1 363 - 635 None None 0
Homo sapiens KSYK_HUMAN 6HM6A 2.1 Active DFGin BLAminus in-in in-in GDK Type1 364 - 632 None X525 2
Homo sapiens KSYK_HUMAN 6HM7A 1.64 Active DFGin BLAminus in-in in-in GDH Type1 363 - 633 None X525 3
Homo sapiens KSYK_HUMAN 3SRVA 1.95 Active DFGin BLAminus in-in in-in S19 Type1 364 - 634 None X525 0
Homo sapiens KSYK_HUMAN 3SRVB 1.95 Active DFGin BLAminus in-in in-in S19 Type1 364 - 632 None None 0
Homo sapiens KSYK_HUMAN 5LMAA 1.43 Active DFGin BLAminus in-in in-in 6ZG Type1 363 - 632 None X525 2
Homo sapiens KSYK_HUMAN 5LMBA 1.95 Active DFGin BLAminus in-in in-in 6ZF Type1 364 - 634 None X525 0
Homo sapiens KSYK_HUMAN 5LMBB 1.95 Active DFGin BLAminus in-in in-in 6ZF Type1 364 - 630 None X525 5
Homo sapiens KSYK_HUMAN 8X5KA 1.8 None DFGin BLAminus in-in in-none 3YT Type1 363 - 632 None None 5
Homo sapiens KSYK_HUMAN 6VOVA 1.95 Active DFGin BLAminus in-in in-in R6D Type1 363 - 629 None None 4
Homo sapiens KSYK_HUMAN 6VOVB 1.95 Active DFGin BLAminus in-in in-in R6D Type1 364 - 633 None None 0
Homo sapiens KSYK_HUMAN 4YJOA 1.6 Active DFGin BLAminus in-in in-in 4DF Type1 363 - 632 None None 3
Homo sapiens KSYK_HUMAN 4YJPA 1.83 Active DFGin BLAminus in-in in-in 4DL Type1 364 - 632 None None 3
Homo sapiens KSYK_HUMAN 4YJQA 1.34 Inactive DFGin BLAminus in-out in-in 4DK Type1 364 - 633 None X525,X526 0
Homo sapiens KSYK_HUMAN 4YJRA 1.32 Inactive DFGin BLAminus in-out in-in 4DJ Type1 364 - 633 None X525,X526 0
Homo sapiens KSYK_HUMAN 4YJSA 2.22 Active DFGin BLAminus in-in in-in 4DN Type1 364 - 632 None None 0
Homo sapiens KSYK_HUMAN 4YJTA 1.52 Inactive DFGin BLAminus in-out in-in 4DQ Type1 364 - 633 None X525,X526 0
Homo sapiens KSYK_HUMAN 4YJUA 1.67 Inactive DFGin BLAminus in-out in-in 4DO Type1 364 - 633 None X525,X526 3
Homo sapiens KSYK_HUMAN 4YJVA 1.652 Inactive DFGin BLAminus in-out in-in 4DT Type1 364 - 633 None X525,X526 0
Homo sapiens KSYK_HUMAN 5TR6A 1.93 None DFGin BLAminus in-none in-in 7KG Type1 362 - 635 None None 0
Homo sapiens KSYK_HUMAN 5TT7A 1.77 Active DFGin BLAminus in-in in-in 7KF Type1 358 - 635 None None 0
Homo sapiens KSYK_HUMAN 4RSSA 1.83 Inactive DFGin BLAminus in-in in-out 4MG Type1 364 - 634 None None 0
Homo sapiens KSYK_HUMAN 4XG3A 2.3 Inactive DFGin BLAminus in-out in-in X3G Type1 363 - 634 None None 0
Homo sapiens KSYK_HUMAN 4XG3B 2.3 Active DFGin BLAminus in-in in-in X3G Type1 363 - 633 None None 4
Homo sapiens KSYK_HUMAN 4XG4A 2.3 Active DFGin BLAminus in-in in-in X4G Type1 363 - 635 None None 4
Homo sapiens KSYK_HUMAN 4XG6A 2.4 None DFGin BLAminus in-in in-none X6G Type1 363 - 635 None None 3
Homo sapiens KSYK_HUMAN 4XG7A 1.76 Inactive DFGin BLAminus in-in in-out X7G Type1 364 - 635 None None 0
Homo sapiens KSYK_HUMAN 4XG8A 2.4 None DFGin BLAminus in-out in-none X8G Type1 366 - 635 None None 3
Homo sapiens KSYK_HUMAN 4XG8C 2.4 None DFGin BLAminus in-in in-none X8G Type1 364 - 629 None None 5
Homo sapiens KSYK_HUMAN 4XG9A 2.91 None DFGin BLAminus in-in in-none X9G Type1 363 - 632 None None 6
Homo sapiens KSYK_HUMAN 4XG9B 2.91 None DFGin BLAminus in-in in-none X9G Type1 363 - 634 None None 3
Homo sapiens KSYK_HUMAN 5GHVA 2.8 Active DFGin BLAminus in-in in-in X5G Type1 363 - 635 None None 4
Homo sapiens KSYK_HUMAN 5GHVB 2.8 Active DFGin BLAminus in-in in-in X5G Type1 363 - 635 None None 4
Homo sapiens KSYK_HUMAN 1XBBA 1.57 Active DFGin BLAminus in-in in-in STI Type1 363 - 635 None None 4
Homo sapiens KSYK_HUMAN 1XBCA 2.0 Active DFGin BLAminus in-in in-in STU Type1 363 - 635 None None 0
Homo sapiens KSYK_HUMAN 3FQEA 2.5 Active DFGin BLAminus in-in in-in P5C Type1 363 - 635 None None 3
Homo sapiens KSYK_HUMAN 3FQHA 2.26 Active DFGin BLAminus in-in in-in 057 Type1 363 - 634 None None 0
Homo sapiens KSYK_HUMAN 3FQHB 2.26 Active DFGin BLAminus in-in in-in 057 Type1 363 - 633 None None 4
Homo sapiens KSYK_HUMAN 3FQSA 2.1 Active DFGin BLAminus in-in in-in 585 Type1 363 - 635 None None 4
Homo sapiens KSYK_HUMAN 4FL1A 1.79 Active DFGin BLAminus in-in in-in ANP Type1 363 - 635 None None 0
Homo sapiens KSYK_HUMAN 4FYNA 2.318 Active DFGin BLAminus in-in in-in 0VE Type1 363 - 635 None None 4
Homo sapiens KSYK_HUMAN 4FYOA 1.4 Active DFGin BLAminus in-in in-in 0VF Type1 363 - 635 None None 4
Homo sapiens KSYK_HUMAN 4FZ6A 1.85 Active DFGin BLAminus in-in in-in 0VG Type1 363 - 635 None None 4
Homo sapiens KSYK_HUMAN 4FZ7A 1.75 Active DFGin BLAminus in-in in-in 0VH Type1 363 - 635 None None 4
Homo sapiens KSYK_HUMAN 4GFGA 2.35 Active DFGin BLAminus in-in in-in 0XF Type1 363 - 635 None None 0
Homo sapiens KSYK_HUMAN 4I0RA 2.1 Active DFGin BLAminus in-in in-in 1B4 Type1 363 - 635 None None 4
Homo sapiens KSYK_HUMAN 4I0SA 1.98 Active DFGin BLAminus in-in in-in 1B5 Type1 363 - 635 None None 4
Homo sapiens KSYK_HUMAN 4I0TA 1.7 Inactive DFGin BLAminus in-in in-out 1B6 Type1 363 - 635 None None 5
Homo sapiens KSYK_HUMAN 4PUZA 2.085 Active DFGin BLAminus in-in in-in CG9 Type1 363 - 633 None None 3
Homo sapiens KSYK_HUMAN 4PUZB 2.085 Active DFGin BLAminus in-in in-in CG9 Type1 363 - 635 None None 3
Homo sapiens KSYK_HUMAN 5T68A 2.93 Active DFGin BLAminus in-in in-in 77V Type1 363 - 635 None None 4
Homo sapiens KSYK_HUMAN 5T68B 2.93 Active DFGin BLAminus in-in in-in 77V Type1 363 - 635 None None 4
Homo sapiens KSYK_HUMAN 5TIUA 1.49 Active DFGin BLAminus in-in in-in 7CU Type1 363 - 635 None None 0
Homo sapiens KSYK_HUMAN 3EMGA 2.6 Inactive DFGin BLAminus in-out in-in 685 Type1 365 - 631 None None 4
Homo sapiens KSYK_HUMAN 5Y5TA 1.8 Active DFGin BLAminus in-in in-in 8OR Type1 363 - 635 None None 0
Homo sapiens KSYK_HUMAN 5Y5UA 2.14 Active DFGin BLAminus in-in in-in 8OU Type1 364 - 634 None None 0
Homo sapiens KSYK_HUMAN 5Y5UB 2.14 None DFGin BLAminus in-in in-none 8OU Type1 363 - 629 None None 6
Homo sapiens KSYK_HUMAN 3VF8A 2.08 None DFGin BLAminus in-none in-in 0JE Type1 363 - 635 None None 0
Homo sapiens KSYK_HUMAN 3VF9A 2.3 None DFGin BLAminus in-none in-in 477 Type1 364 - 635 None None 0
Homo sapiens KSYK_HUMAN 4WNMA 2.5 Active DFGin BLAminus in-in in-in 3RT Type1 347 - 635 None None 0
Homo sapiens KSYK_HUMAN 5C26A 1.95 Active DFGin BLAminus in-in in-in 50H Type1 363 - 635 None X525,X526 0
Homo sapiens KSYK_HUMAN 5C27A 2.15 Active DFGin BLAminus in-in in-in 50J Type1 363 - 635 None X525,X526 0
Homo sapiens KSYK_HUMAN 6SSBA 2.08 Active DFGin BLAminus in-in in-in LUE Type1 363 - 635 None None 1
Homo sapiens KSYK_HUMAN 6ZC0A 1.97 Active DFGin BLAminus in-in in-in QDZ Type1 363 - 635 None None 0
Homo sapiens KSYK_HUMAN 6ZCPA 2.2 Active DFGin BLAminus in-in in-in QFK Type1 363 - 635 None None 0
Homo sapiens KSYK_HUMAN 6ZCQA 2.32 Active DFGin BLAminus in-in in-in QFB Type1 363 - 635 None None 1
Homo sapiens KSYK_HUMAN 6ZCRA 1.73 Active DFGin BLAminus in-in in-in 5JG Type1 363 - 635 None None 4
Homo sapiens KSYK_HUMAN 6ZCSA 1.47 Active DFGin BLAminus in-in in-in QFE Type1 363 - 635 None None 1
Homo sapiens KSYK_HUMAN 6ZCUA 1.73 Active DFGin BLAminus in-in in-in 5JG Type1 363 - 635 None None 4
Homo sapiens KSYK_HUMAN 6ZCXA 1.66 Active DFGin BLAminus in-in in-in QFQ Type1 363 - 635 None None 1
Homo sapiens KSYK_HUMAN 6ZCYA 1.81 Active DFGin BLAminus in-in in-in QF8 Type1 363 - 635 None None 1
Homo sapiens KSYK_HUMAN 8BI2A 1.508 Active DFGin BLAminus in-in in-in QR7 Type1 363 - 635 None None 1
Homo sapiens KSYK_HUMAN 4RX7A 1.8 Active DFGin BLAminus in-in in-in 3YV Type1 363 - 635 None None 0
Homo sapiens KSYK_HUMAN 4RX8A 1.59 Active DFGin BLAminus in-in in-in 3YX Type1 364 - 635 None None 1
Homo sapiens KSYK_HUMAN 5CXHA 1.9 Active DFGin BLAminus in-in in-in 55M Type1 363 - 635 K467T None 0
Homo sapiens KSYK_HUMAN 5CXZA 1.7 Active DFGin BLAminus in-in in-in 55U Type1 363 - 635 K467T None 1
Homo sapiens KSYK_HUMAN 4RX9A 1.75 Active DFGin BLAminus in-in in-in 3YT Type1 363 - 635 None None 1
Homo sapiens KSYK_HUMAN 4PX6A 1.6 Active DFGin BLAminus in-in in-in 2X6 Type1 364 - 635 K467T None 4
Homo sapiens KSYK_HUMAN 5CY3A 1.76 Active DFGin BLAminus in-in in-in 55Y Type1 360 - 635 K467T None 0
Homo sapiens KSYK_HUMAN 4FL3A 1.9 Inactive DFGin BLBplus out-out out-none ANP Type1 9 - 635 Y348F,Y352F None 13
Homo sapiens KSYK_HUMAN 4FL2A 2.19 Inactive DFGin BLBplus out-out out-out ANP Type1 9 - 635 None None 0
Homo sapiens KSYK_HUMAN 3TUCA 2.1 Inactive DFGin BLBplus out-out none-none FPW Type1.5_Front 358 - 633 None None 19
Homo sapiens KSYK_HUMAN 3TUBA 2.23 Inactive DFGout BBAminus in-out none-none FPU Type2 362 - 633 None None 19
Homo sapiens KSYK_HUMAN 3TUDA 2.33 Inactive DFGout None in-in none-in FPX Type2 363 - 635 None None 18

SYK (Tyrosine-protein kinase SYK)

No non-human structures known.