4DFL

SYK (Tyrosine-protein kinase SYK)
Group: TYR
Uniprot: KSYK_HUMAN
Organism: Homo sapiens
Domain boundary: 370 - 628
Resolu: 1.98

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 0K0 Type1 363 - 635 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       372        382        392        402 
VYLDRKLLTL EDKELGSgnf GTVKKGYYQM kkVVKTVAVK 
       412        422        432        442 
ILkneandPA LKDELLAEAN VMQQLDNPYI VRMIGICEAE 
       452        462        472        482 
SWMLVMEMAE LGPLNKYLQQ NRHVKDKNII ELVHQVSMGM 
       492        502        512        522 
KYLEESNFVH RDLAARNVLL VTQHYAKISD FGLSKALRAD 
       532        542        552        562 
ENYYKAQTHG KWPVKWYAPE CINYYKFSSK SDVWSFGVLM 
       572        582        592        602 
WEAFSYGQKP YRGMKGSEVT AMLEKGERMG CPAGCPREMY 
       612        622        632 
DLMNLCWTYD VENRPGFAAV ELRLRNYYYD VVNE
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None