6HM6

SYK (Tyrosine-protein kinase SYK)
Group: TYR
Uniprot: KSYK_HUMAN
Organism: Homo sapiens
Domain boundary: 370 - 628
Resolu: 2.1

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in GDK Type1 364 - 632 2
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       369        379        389        399 
pkevYLDRKL LTLEDKELGS GNFGTVKKGY YQMkKVVKTV 
       409        419        429        439 
AVKILknean DPALKDELLA EANVMQQLDN PYIVRMIGIC 
       449        459        469        479 
EAESWMLVME MAELGPLNKY LQQNRHVKDK NIIELVHQVS 
       489        499        509        519 
MGMKYLEESN FVHRDLAARN VLLVTQHYAK ISDFGLSKAL 
       529        539        549        559 
RADENYYKAQ thGKWPVKWY APECINYYKF SSKSDVWSFG 
       569        579        589        599 
VLMWEAFSYG QKPYRGMKGS EVTAMLEKGE RMGCPAGCPR 
       609        619        629 
EMYDLMNLCW TYDVENRPGF AAVELRLRNY YYDvvn
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X525