4YJT

SYK (Tyrosine-protein kinase SYK)
Group: TYR
Uniprot: KSYK_HUMAN
Organism: Homo sapiens
Domain boundary: 370 - 628
Resolu: 1.52

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-out in-in 4DQ Type1 364 - 633 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       364        374        384        394 
peeirpkevY LDRKLLTLED KELGSGNFGT VKKGYYQMKK 
       404        414        424        434 
VVKTVAVKIL KNEANDPALK DELLAEANVM QQLDNPYIVR 
       444        454        464        474 
MIGICEAESW MLVMEMAELG PLNKYLQQNR HVKDKNIIEL 
       484        494        504        514 
VHQVSMGMKY LEESNFVHRD LAARNVLLVT QHYAKISDFG 
       524        534        544        554 
LSKALRADEN YYKAQTHGKW PVKWYAPECI NYYKFSSKSD 
       564        574        584        594 
VWSFGVLMWE AFSYGQKPYR GMKGSEVTAM LEKGERMGCP 
       604        614        624        634 
AGCPREMYDL MNLCWTYDVE NRPGFAAVEL RLRNYYYDVv 

n
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X525,X526