AF-P04049-K1

RAF1 (RAF proto-oncogene serine/threonine-protein kinase)
Group: TKL
Uniprot: RAF1_HUMAN
Organism: Homo sapiens
Domain boundary: 349 - 608
Resolu: -1.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in No_ligand No_ligand 341 - 616 0
Representative sequence - Chain A
350 360 370 380
YWEIEASEVM LSTRIGSGSF GTVYKGKWHG DVAVKILKVV
390 400 410 420
DPTPEQFQAF RNEVAVLRKT RHVNILLFMG YMTKDNLAIV
430 440 450 460
TQWCEGSSLY KHLHVQETKF QMFQLIDIAR QTAQGMDYLH
470 480 490 500
AKNIIHRDMK SNNIFLHEGL TVKIGDFGLA TVKSRWSGSQ
510 520 530 540
QVEQPTGSVL WMAPEVIRMQ DNNPFSFQSD VYSYGIVLYE
550 560 570 580
LMTGELPYSH INNRDQIIFM VGRGYASPDL SKLYKNCPKA
590 600 610
MKRLVADCVK KVKEERPLFP QILSSIELLQ HSLPKI
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None