MAPK9 (Mitogen-activated protein kinase 9)

Group: CMGC
Uniprot: MK09_HUMAN
Domain boundary: 26 - 321


Total number of chains: 9
Spatial Dihedral Chains Representative
DFGin BLAminus 1 AF-P45984-K1A
DFGin ABAminus 4 7N8TA
DFGin None 2 7CMLB
DFGout None 2 3NPCA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
8ELCA 2.072 Inactive DFGin ABAminus out-out out-out Y56 Type1 9 - 363 None None 0
3E7OA 2.14 Inactive DFGin ABAminus in-in out-out 35F Type1 9 - 361 C177S,C222S,K250A,K251A,K265A,K270A None 0
3E7OB 2.14 Inactive DFGin ABAminus in-in none-none 35F Type1 8 - 362 C177S,C222S,K250A,K251A,K265A,K270A None 16
7N8TA 1.69 Inactive DFGin ABAminus in-out out-out AMP Type1 10 - 364 None None 0
AF-P45984-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 18 - 329 None None 0
7CMLA 2.15 Inactive DFGin None in-in none-none No_ligand No_ligand 1 - 364 D3K,C6V,S8N,Q14E,K203A,E204A,K250A,K251A None 16
7CMLB 2.15 Inactive DFGin None in-in none-none No_ligand No_ligand 1 - 364 D3K,C6V,S8N,Q14E,K203A,E204A,K250A,K251A None 16
3NPCA 2.35 Inactive DFGout None in-in out-out B96 Type2 7 - 363 D3K,C6V,S8N,Q14E,K203A,E204A,K250A,K251A None 0
3NPCB 2.35 Inactive DFGout None in-in out-out B96 Type2 8 - 363 D3K,C6V,S8N,Q14E,K203A,E204A,K250A,K251A None 0

MAPK9 (Mitogen-activated protein kinase 9)

Group: CMGC
Total number of chains: 9
Spatial Dihedral Chains Representative
DFGin BLAminus 1 AF-P45984-K1A
DFGin ABAminus 4 7N8TA
DFGin None 2 7CMLB
DFGout None 2 3NPCA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens MK09_HUMAN 8ELCA 2.072 Inactive DFGin ABAminus out-out out-out Y56 Type1 9 - 363 None None 0
Homo sapiens MK09_HUMAN 3E7OA 2.14 Inactive DFGin ABAminus in-in out-out 35F Type1 9 - 361 C177S,C222S,K250A,K251A,K265A,K270A None 0
Homo sapiens MK09_HUMAN 3E7OB 2.14 Inactive DFGin ABAminus in-in none-none 35F Type1 8 - 362 C177S,C222S,K250A,K251A,K265A,K270A None 16
Homo sapiens MK09_HUMAN 7N8TA 1.69 Inactive DFGin ABAminus in-out out-out AMP Type1 10 - 364 None None 0
Homo sapiens MK09_HUMAN AF-P45984-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 18 - 329 None None 0
Homo sapiens MK09_HUMAN 7CMLA 2.15 Inactive DFGin None in-in none-none No_ligand No_ligand 1 - 364 D3K,C6V,S8N,Q14E,K203A,E204A,K250A,K251A None 16
Homo sapiens MK09_HUMAN 7CMLB 2.15 Inactive DFGin None in-in none-none No_ligand No_ligand 1 - 364 D3K,C6V,S8N,Q14E,K203A,E204A,K250A,K251A None 16
Homo sapiens MK09_HUMAN 3NPCA 2.35 Inactive DFGout None in-in out-out B96 Type2 7 - 363 D3K,C6V,S8N,Q14E,K203A,E204A,K250A,K251A None 0
Homo sapiens MK09_HUMAN 3NPCB 2.35 Inactive DFGout None in-in out-out B96 Type2 8 - 363 D3K,C6V,S8N,Q14E,K203A,E204A,K250A,K251A None 0

MAPK9 (Mitogen-activated protein kinase 9)

No non-human structures known.