MAPK11 (Mitogen-activated protein kinase 11)

Group: CMGC
Uniprot: MK11_HUMAN
Domain boundary: 24 - 308


Total number of chains: 7
Spatial Dihedral Chains Representative
DFGin BLAminus 1 AF-Q15759-K1A
DFGin ABAminus 3 3GC8A
DFGin None 1 3GC9A
DFGout BBAminus 1 3GP0A
DFGout None 1 8YGWA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
3GC9B 2.05 Inactive DFGin ABAminus in-out out-out B45 Type1 2 - 349 C119S,C162S None 9
3GC8A 2.4 Inactive DFGin ABAminus in-out out-out B45 Type1 3 - 349 C162S None 0
3GC8B 2.4 Inactive DFGin ABAminus in-out out-out B45 Type1 4 - 349 C162S None 0
AF-Q15759-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 16 - 316 None None 0
3GC9A 2.05 Inactive DFGin None in-out none-out B45 Type1 3 - 348 C119S,C162S None 11
3GP0A 1.9 Inactive DFGout BBAminus in-out none-out NIL Type2 5 - 348 None None 7
8YGWA 3.301 Inactive DFGout None in-out none-out B96 Type2 5 - 348 None None 13

MAPK11 (Mitogen-activated protein kinase 11)

Group: CMGC
Total number of chains: 7
Spatial Dihedral Chains Representative
DFGin BLAminus 1 AF-Q15759-K1A
DFGin ABAminus 3 3GC8A
DFGin None 1 3GC9A
DFGout BBAminus 1 3GP0A
DFGout None 1 8YGWA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens MK11_HUMAN 3GC9B 2.05 Inactive DFGin ABAminus in-out out-out B45 Type1 2 - 349 C119S,C162S None 9
Homo sapiens MK11_HUMAN 3GC8A 2.4 Inactive DFGin ABAminus in-out out-out B45 Type1 3 - 349 C162S None 0
Homo sapiens MK11_HUMAN 3GC8B 2.4 Inactive DFGin ABAminus in-out out-out B45 Type1 4 - 349 C162S None 0
Homo sapiens MK11_HUMAN AF-Q15759-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 16 - 316 None None 0
Homo sapiens MK11_HUMAN 3GC9A 2.05 Inactive DFGin None in-out none-out B45 Type1 3 - 348 C119S,C162S None 11
Homo sapiens MK11_HUMAN 3GP0A 1.9 Inactive DFGout BBAminus in-out none-out NIL Type2 5 - 348 None None 7
Homo sapiens MK11_HUMAN 8YGWA 3.301 Inactive DFGout None in-out none-out B96 Type2 5 - 348 None None 13

MAPK11 (Mitogen-activated protein kinase 11)

No non-human structures known.