3GC8

MAPK11 (Mitogen-activated protein kinase 11)
Group: CMGC
Uniprot: MK11_HUMAN
Organism: Homo sapiens
Domain boundary: 24 - 308
Resolu: 2.4

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-out out-out B45 Type1 3 - 349 0
B Inactive DFGin ABAminus in-out out-out B45 Type1 4 - 349 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         4         14         24         34 
gshmlemsgP RAGFYRQELN KTVWEVPQRL QGLRPVGSGA 
        44         54         64         74 
YGSVCSAYDA RLRQKVAVKK LSRPFQSLIH ARRTYRELRL 
        84         94        104        114 
LKHLKHENVI GLLDVFTPAT SIEDFSEVYL VTTLMGADLN 
       124        134        144        154 
NIVKCQALSD EHVQFLVYQL LRGLKYIHSA GIIHRDLKPS 
       164        174        184        194 
NVAVNEDSEL RILDFGLARQ ADEEMTGYVA TRWYRAPEIM 
       204        214        224        234 
LNWMHYNQTV DIWSVGCIMA ELLQGKALFP GSDYIDQLKR 
       244        254        264        274 
IMEVVGTPSP EVLAKISSEH ARTYIQSLPP MPQKDLSSIF 
       284        294        304        314 
RGANPLAIDL LGRMLVLDSD QRVSAAEALA HAYFSQYHDP 
       324        334        344        354 
EDEPEAEPYD ESVEAKERTL EEWKELTYQE VLSFKppepp 
       364 
kppgsleieq
Lower-case residues are disordered in structure.
Mutations: C162S
Phosphorylation: None