PDB: 9O0U — 2 kinases

Total number of chains: 8
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 5 62.5% 9O0UA
DFGin BLAminus 1 12.5% 9O0UG
DFGin BLAplus 1 12.5% 9O0UE
DFGin BLBminus 1 12.5% 9O0UC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 9O0UB Q02750 30 380 393.0 CHU:401 Type1 Inactive DFGin 6.1693 14.0852 BLBplus -152.21, 168.43 59.39, 48.73 -101.51, 163.52 46.19, 86.69 -79.7, 84.36 out-out out 15.4302 Saltbr-out 16.8168 HRD-in -71.69, -48.17 74.87, -6.64 out-out-out SNCooo out-out ActLoopNT-out 9.681 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -135.55, 157.08 APE9-dihe-na -122.47, 145.42 APE8-dihe-out -102.69, -27.28 APE8-rot-in 280.53 APE67-dihe-out -148.15, 135.27 -137.0, 174.84 APE12-dist-out 16.861 APE11-dist-out 17.0165 APE10-dist-out 21.8105 APE9-dist-out 12.4425 S218A,S222A None None XRAY 2.91 0.232 0.264 B 395.0 322.0 29 26 26 0 [[68, 361]] 1.0 9o0u STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0UH Q02750 30 380 393.0 CHU:401,ANP:402 Type1,ATPlike Inactive DFGin 6.2263 14.2396 BLBplus -153.68, 170.44 61.41, 47.24 -102.95, 164.39 45.69, 94.01 -79.55, 83.41 out-out out 15.5809 Saltbr-out 15.7853 HRD-in -74.86, -48.68 73.9, -6.25 out-out-out SNCooo out-out ActLoopNT-out 9.583 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -141.84, 152.52 APE9-dihe-na -130.16, 177.33 APE8-dihe-out -105.34, -25.09 APE8-rot-out 37.73 APE67-dihe-out -147.39, 136.35 -136.55, 176.51 APE12-dist-out 17.387 APE11-dist-out 17.659 APE10-dist-out 22.2151 APE9-dist-out 12.9967 S218A,S222A None None XRAY 2.91 0.232 0.264 H 395.0 315.0 36 26 26 0 [[68, 361]] 1.0 9o0u STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0UD Q02750 31 380 393.0 CHU:401 Type3 Inactive DFGin 6.2577 14.2452 BLBplus -155.2, 170.07 62.24, 48.49 -103.46, 163.38 44.86, 81.23 -80.64, 82.9 out-out out 15.8042 Saltbr-out 15.5601 HRD-in -72.61, -47.48 72.0, -5.51 out-out-out SNCooo out-out ActLoopNT-out 9.507 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -145.99, 151.57 APE9-dihe-na -129.02, 151.01 APE8-dihe-out -101.49, -25.69 APE8-rot-in 295.14 APE67-dihe-out -149.54, 133.77 -134.81, 174.59 APE12-dist-out 17.407 APE11-dist-out 17.5585 APE10-dist-out 22.6481 APE9-dist-out 12.7538 S218A,S222A None None XRAY 2.91 0.232 0.264 D 395.0 317.0 33 26 26 0 [[68, 361]] 1.0 9o0u STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0UF Q02750 30 380 393.0 CHU:401 Type3 Inactive DFGin 6.24 14.2415 BLBplus -149.4, 162.55 67.26, 47.9 -103.2, 163.92 46.52, 88.85 -79.29, 85.22 out-out out 15.5394 Saltbr-out 16.2358 HRD-in -74.73, -46.69 72.92, -6.37 out-out-out SNCooo out-out ActLoopNT-out 9.8344 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -124.83, 125.43 APE9-dihe-na -156.49, 116.77 APE8-dihe-out -98.23, -8.63 APE8-rot-in 320.21 APE67-dihe-out -147.81, 133.84 -133.15, 172.65 APE12-dist-out 18.6641 APE11-dist-out 16.7859 APE10-dist-out 21.1732 APE9-dist-out 12.5375 S218A,S222A None None XRAY 2.91 0.232 0.264 F 395.0 322.0 29 26 26 0 [[68, 361]] 1.0 9o0u STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL RAF1 RAF1_HUMAN 9O0UG P04049 341 614 648.0 324:701 Type1 Inactive DFGin 6.6427 14.5362 BLAminus -137.03, -164.72 64.05, 59.07 -91.31, 23.03 298.27, 111.42 -70.02, -22.85 in-in in 8.466 Saltbr-in 2.7929 HRD-in -67.69, -46.18 73.87, -6.26 in-in-out SNCiio in-out ActLoopNT-in 3.4083 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -147.61, -172.9 APE9-dihe-na 96.11, -111.47 APE8-dihe-in -121.52, 159.07 APE8-rot-out 179.33 APE67-dihe-in -61.77, -27.13 -108.62, -7.48 APE12-dist-in 9.3284 APE11-dist-in 9.0351 APE10-dist-out 10.4777 APE9-dist-out 9.744 Y340D,Y341D None None XRAY 2.91 0.232 0.264 G 280.0 265.0 9 30 21 9 [[349, 608]] 1.0 9o0u TKL_RAF1_HUMAN TKL 2.6e-81 279.0 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0UE P04049 339 613 648.0 324:701 Type1.5_Back Inactive DFGin 5.9555 13.4189 BLAplus -138.96, -169.14 62.02, 34.27 -105.27, 31.97 55.75, 93.21 -64.59, -47.5 out-none out 11.6319 Saltbr-none 999.0 HRD-in -66.55, -46.99 72.02, -8.83 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -79.43 APE8-dihe-in -132.83, 160.57 APE8-rot-out 180.68 APE67-dihe-in -62.16, -27.71 -107.14, -6.5 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 9.74 Y340D,Y341D None None XRAY 2.91 0.232 0.264 E 280.0 258.0 17 30 13 17 [[349, 608]] 1.0 9o0u TKL_RAF1_HUMAN TKL 2.6e-81 279.0 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0UC P04049 339 614 648.0 324:701 Type1 Inactive DFGin 6.4118 14.92 BLBminus -135.2, -162.93 65.39, 47.79 -89.17, 153.49 305.13, 119.24 148.83, -36.3 in-in in 8.1119 Saltbr-in 3.1081 HRD-in -65.51, -42.52 74.23, -8.63 in-in-out SNCiio in-out ActLoopNT-in 3.2736 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, -140.95 APE9-dihe-na 87.04, -108.57 APE8-dihe-in -126.35, 163.82 APE8-rot-out 179.91 APE67-dihe-in -66.05, -28.24 -108.28, -15.46 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 9.537 APE9-dist-out 7.8436 Y340D,Y341D None None XRAY 2.91 0.232 0.264 C 280.0 264.0 12 30 18 12 [[349, 608]] 1.0 9o0u TKL_RAF1_HUMAN TKL 2.6e-81 279.0 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0UA P04049 339 612 648.0 324:701 Type1.5_Back Inactive DFGin 5.49 13.4253 BLBplus -137.77, -168.21 60.54, 23.67 -97.39, 164.85 62.85, 94.03 74.33, 173.3 out-none out 11.6361 Saltbr-none 999.0 HRD-in -67.32, -47.26 72.53, -10.19 none-out-out SNCnoo out-out ActLoopNT-out 8.5215 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -79.91, 164.26 APE9-dihe-na 133.94, -179.25 APE8-dihe-in -151.13, 161.47 APE8-rot-out 181.14 APE67-dihe-in -63.28, -28.75 -107.76, -7.41 APE12-dist-out 21.2876 APE11-dist-out 15.3594 APE10-dist-out 15.2178 APE9-dist-out 10.0158 Y340D,Y341D None None XRAY 2.91 0.232 0.264 A 280.0 267.0 7 30 23 7 [[349, 608]] 1.0 9o0u TKL_RAF1_HUMAN TKL 2.6e-81 279.0 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase

PDB: 9O0U — 2 kinases

Total number of chains: 8
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 5 62.5% 9O0UA
DFGin BLAminus 1 12.5% 9O0UG
DFGin BLAplus 1 12.5% 9O0UE
DFGin BLBminus 1 12.5% 9O0UC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 9O0UB Q02750 30 380 393.0 CHU:401 Type1 Inactive DFGin 6.1693 14.0852 BLBplus -152.21, 168.43 59.39, 48.73 -101.51, 163.52 46.19, 86.69 -79.7, 84.36 out-out out 15.4302 Saltbr-out 16.8168 HRD-in -71.69, -48.17 74.87, -6.64 out-out-out SNCooo out-out ActLoopNT-out 9.681 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -135.55, 157.08 APE9-dihe-na -122.47, 145.42 APE8-dihe-out -102.69, -27.28 APE8-rot-in 280.53 APE67-dihe-out -148.15, 135.27 -137.0, 174.84 APE12-dist-out 16.861 APE11-dist-out 17.0165 APE10-dist-out 21.8105 APE9-dist-out 12.4425 S218A,S222A None None XRAY 2.91 0.232 0.264 B 395.0 322.0 29 26 26 0 [[68, 361]] 1.0 9o0u Homo sapiens STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0UH Q02750 30 380 393.0 CHU:401,ANP:402 Type1,ATPlike Inactive DFGin 6.2263 14.2396 BLBplus -153.68, 170.44 61.41, 47.24 -102.95, 164.39 45.69, 94.01 -79.55, 83.41 out-out out 15.5809 Saltbr-out 15.7853 HRD-in -74.86, -48.68 73.9, -6.25 out-out-out SNCooo out-out ActLoopNT-out 9.583 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -141.84, 152.52 APE9-dihe-na -130.16, 177.33 APE8-dihe-out -105.34, -25.09 APE8-rot-out 37.73 APE67-dihe-out -147.39, 136.35 -136.55, 176.51 APE12-dist-out 17.387 APE11-dist-out 17.659 APE10-dist-out 22.2151 APE9-dist-out 12.9967 S218A,S222A None None XRAY 2.91 0.232 0.264 H 395.0 315.0 36 26 26 0 [[68, 361]] 1.0 9o0u Homo sapiens STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0UD Q02750 31 380 393.0 CHU:401 Type3 Inactive DFGin 6.2577 14.2452 BLBplus -155.2, 170.07 62.24, 48.49 -103.46, 163.38 44.86, 81.23 -80.64, 82.9 out-out out 15.8042 Saltbr-out 15.5601 HRD-in -72.61, -47.48 72.0, -5.51 out-out-out SNCooo out-out ActLoopNT-out 9.507 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -145.99, 151.57 APE9-dihe-na -129.02, 151.01 APE8-dihe-out -101.49, -25.69 APE8-rot-in 295.14 APE67-dihe-out -149.54, 133.77 -134.81, 174.59 APE12-dist-out 17.407 APE11-dist-out 17.5585 APE10-dist-out 22.6481 APE9-dist-out 12.7538 S218A,S222A None None XRAY 2.91 0.232 0.264 D 395.0 317.0 33 26 26 0 [[68, 361]] 1.0 9o0u Homo sapiens STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0UF Q02750 30 380 393.0 CHU:401 Type3 Inactive DFGin 6.24 14.2415 BLBplus -149.4, 162.55 67.26, 47.9 -103.2, 163.92 46.52, 88.85 -79.29, 85.22 out-out out 15.5394 Saltbr-out 16.2358 HRD-in -74.73, -46.69 72.92, -6.37 out-out-out SNCooo out-out ActLoopNT-out 9.8344 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -124.83, 125.43 APE9-dihe-na -156.49, 116.77 APE8-dihe-out -98.23, -8.63 APE8-rot-in 320.21 APE67-dihe-out -147.81, 133.84 -133.15, 172.65 APE12-dist-out 18.6641 APE11-dist-out 16.7859 APE10-dist-out 21.1732 APE9-dist-out 12.5375 S218A,S222A None None XRAY 2.91 0.232 0.264 F 395.0 322.0 29 26 26 0 [[68, 361]] 1.0 9o0u Homo sapiens STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL RAF1 RAF1_HUMAN 9O0UG P04049 341 614 648.0 324:701 Type1 Inactive DFGin 6.6427 14.5362 BLAminus -137.03, -164.72 64.05, 59.07 -91.31, 23.03 298.27, 111.42 -70.02, -22.85 in-in in 8.466 Saltbr-in 2.7929 HRD-in -67.69, -46.18 73.87, -6.26 in-in-out SNCiio in-out ActLoopNT-in 3.4083 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -147.61, -172.9 APE9-dihe-na 96.11, -111.47 APE8-dihe-in -121.52, 159.07 APE8-rot-out 179.33 APE67-dihe-in -61.77, -27.13 -108.62, -7.48 APE12-dist-in 9.3284 APE11-dist-in 9.0351 APE10-dist-out 10.4777 APE9-dist-out 9.744 Y340D,Y341D None None XRAY 2.91 0.232 0.264 G 280.0 265.0 9 30 21 9 [[349, 608]] 1.0 9o0u Homo sapiens TKL_RAF1_HUMAN TKL 2.6e-81 279.0 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0UE P04049 339 613 648.0 324:701 Type1.5_Back Inactive DFGin 5.9555 13.4189 BLAplus -138.96, -169.14 62.02, 34.27 -105.27, 31.97 55.75, 93.21 -64.59, -47.5 out-none out 11.6319 Saltbr-none 999.0 HRD-in -66.55, -46.99 72.02, -8.83 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -79.43 APE8-dihe-in -132.83, 160.57 APE8-rot-out 180.68 APE67-dihe-in -62.16, -27.71 -107.14, -6.5 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 9.74 Y340D,Y341D None None XRAY 2.91 0.232 0.264 E 280.0 258.0 17 30 13 17 [[349, 608]] 1.0 9o0u Homo sapiens TKL_RAF1_HUMAN TKL 2.6e-81 279.0 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0UC P04049 339 614 648.0 324:701 Type1 Inactive DFGin 6.4118 14.92 BLBminus -135.2, -162.93 65.39, 47.79 -89.17, 153.49 305.13, 119.24 148.83, -36.3 in-in in 8.1119 Saltbr-in 3.1081 HRD-in -65.51, -42.52 74.23, -8.63 in-in-out SNCiio in-out ActLoopNT-in 3.2736 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, -140.95 APE9-dihe-na 87.04, -108.57 APE8-dihe-in -126.35, 163.82 APE8-rot-out 179.91 APE67-dihe-in -66.05, -28.24 -108.28, -15.46 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 9.537 APE9-dist-out 7.8436 Y340D,Y341D None None XRAY 2.91 0.232 0.264 C 280.0 264.0 12 30 18 12 [[349, 608]] 1.0 9o0u Homo sapiens TKL_RAF1_HUMAN TKL 2.6e-81 279.0 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0UA P04049 339 612 648.0 324:701 Type1.5_Back Inactive DFGin 5.49 13.4253 BLBplus -137.77, -168.21 60.54, 23.67 -97.39, 164.85 62.85, 94.03 74.33, 173.3 out-none out 11.6361 Saltbr-none 999.0 HRD-in -67.32, -47.26 72.53, -10.19 none-out-out SNCnoo out-out ActLoopNT-out 8.5215 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -79.91, 164.26 APE9-dihe-na 133.94, -179.25 APE8-dihe-in -151.13, 161.47 APE8-rot-out 181.14 APE67-dihe-in -63.28, -28.75 -107.76, -7.41 APE12-dist-out 21.2876 APE11-dist-out 15.3594 APE10-dist-out 15.2178 APE9-dist-out 10.0158 Y340D,Y341D None None XRAY 2.91 0.232 0.264 A 280.0 267.0 7 30 23 7 [[349, 608]] 1.0 9o0u Homo sapiens TKL_RAF1_HUMAN TKL 2.6e-81 279.0 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase

PDB: 9O0U — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name