PDB: 8YP4 — STE MP2K1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 1 50.0% 8YP4A
DFGout None 1 50.0% 8YP4B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 8YP4A Q02750 34 384 393.0 WNT:401 Type1 Inactive DFGin 5.6499 12.5748 None -114.29, -33.59 -28.46, 108.03 -125.65, 141.38 278.55, 110.59 -62.12, 167.08 out-out out 15.0636 Saltbr-out 17.0816 HRD-out 70.59, -102.97 160.56, -67.88 out-out-out SNCooo out-out ActLoopNT-out 13.7522 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_nnoo APE10-dihe-na 999.0, 77.83 APE9-dihe-na -121.62, 81.96 APE8-dihe-out 101.02, -24.75 APE8-rot-in 322.27 APE67-dihe-out -132.46, 136.61 -111.44, 133.26 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 16.1822 APE9-dist-out 15.9962 T286A,T292A,S298A None None XRAY 2.35 0.21 0.284 A 365.0 305.0 46 26 17 9 [[68, 361]] 1.0 8yp4 STE_MAP2K1_HUMAN STE 1.9e-97 331.7 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 8YP4B Q02750 43 383 393.0 WNT:402 Type1 Inactive DFGout 11.3253 6.4247 None -108.9, 111.79 -94.09, -121.26 66.37, 140.13 107.59, 69.46 128.79, 15.36 out-out out 15.3476 Saltbr-out 16.193 HRD-out 49.23, 166.44 96.35, 147.86 out-out-out SNCooo out-out ActLoopNT-out 11.7919 ActLoopCT-out nonTYR APEdihe_aanoo APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -125.63 APE8-rot-out 65.35 APE67-dihe-out 121.59, -95.83 78.91, 128.14 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 T286A,T292A,S298A None None XRAY 2.35 0.21 0.284 B 365.0 299.0 42 26 15 11 [[68, 361]] 1.0 8yp4 STE_MAP2K1_HUMAN STE 1.9e-97 331.7 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1

PDB: 8YP4 — STE MP2K1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 1 50.0% 8YP4A
DFGout None 1 50.0% 8YP4B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 8YP4A Q02750 34 384 393.0 WNT:401 Type1 Inactive DFGin 5.6499 12.5748 None -114.29, -33.59 -28.46, 108.03 -125.65, 141.38 278.55, 110.59 -62.12, 167.08 out-out out 15.0636 Saltbr-out 17.0816 HRD-out 70.59, -102.97 160.56, -67.88 out-out-out SNCooo out-out ActLoopNT-out 13.7522 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_nnoo APE10-dihe-na 999.0, 77.83 APE9-dihe-na -121.62, 81.96 APE8-dihe-out 101.02, -24.75 APE8-rot-in 322.27 APE67-dihe-out -132.46, 136.61 -111.44, 133.26 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 16.1822 APE9-dist-out 15.9962 T286A,T292A,S298A None None XRAY 2.35 0.21 0.284 A 365.0 305.0 46 26 17 9 [[68, 361]] 1.0 8yp4 Homo sapiens STE_MAP2K1_HUMAN STE 1.9e-97 331.7 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 8YP4B Q02750 43 383 393.0 WNT:402 Type1 Inactive DFGout 11.3253 6.4247 None -108.9, 111.79 -94.09, -121.26 66.37, 140.13 107.59, 69.46 128.79, 15.36 out-out out 15.3476 Saltbr-out 16.193 HRD-out 49.23, 166.44 96.35, 147.86 out-out-out SNCooo out-out ActLoopNT-out 11.7919 ActLoopCT-out nonTYR APEdihe_aanoo APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -125.63 APE8-rot-out 65.35 APE67-dihe-out 121.59, -95.83 78.91, 128.14 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 T286A,T292A,S298A None None XRAY 2.35 0.21 0.284 B 365.0 299.0 42 26 15 11 [[68, 361]] 1.0 8yp4 Homo sapiens STE_MAP2K1_HUMAN STE 1.9e-97 331.7 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1

PDB: 8YP4 — STE MP2K1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name