PDB: 7QWK — OTHER E2AK4_HUMAN

Total number of chains: 8
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 6 75.0% 7QWKD
DFGinter BABtrans 1 12.5% 7QWKH
DFGinter None 1 12.5% 7QWKF
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKH Q9P2K8 584 1006 1649.0 G41:1701 Type1 Inactive DFGinter 8.0462 8.4367 BABtrans -55.61, 130.2 -124.52, 16.67 -106.93, 111.28 188.62, 73.34 126.77, 18.12 out-out out 11.0562 Saltbr-out 7.6256 HRD-in -81.65, -56.1 78.04, -22.14 out-out-out SNCooo out-out ActLoopNT-out 5.2947 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_oooo APE10-dihe-na -63.36, -44.68 APE9-dihe-na -61.4, -37.94 APE8-dihe-out -73.72, -24.45 APE8-rot-none 999.0 APE67-dihe-in -74.17, -2.36 -79.69, -19.77 APE12-dist-out 22.3633 APE11-dist-out 21.0532 APE10-dist-out 23.9535 APE9-dist-out 13.5058 D848N None None XRAY 2.3 0.214 0.243 H 318.0 259.0 38 46 27 19 [[277, 541], [590, 1001]] 2.0 7qwk OTHER_EIF2AK4-2_HUMAN OTHER 2.1e-46 164.7 1.0 256.0 256.0 865 866 867 869 871 619 636 640 845 847 846 848.0 925 911 906 905 904 903 902 901 900 803 eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKF Q9P2K8 584 1005 1649.0 G41:1701 Type1 Inactive DFGinter 8.0374 8.1815 None -60.18, 141.19 -134.64, 94.13 -155.09, 69.13 206.23, 33.34 148.0, 161.57 out-out out 11.1145 Saltbr-out 8.211 HRD-in -90.54, -49.57 66.47, -5.34 out-out-out SNCooo out-out ActLoopNT-out 6.628 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_oooo APE10-dihe-na 134.32, -54.28 APE9-dihe-na -62.87, -46.85 APE8-dihe-out -62.12, -35.02 APE8-rot-none 999.0 APE67-dihe-in -70.96, -4.61 -71.45, -20.51 APE12-dist-out 23.468 APE11-dist-out 21.7478 APE10-dist-out 24.3155 APE9-dist-out 13.581 D848N None None XRAY 2.3 0.214 0.243 F 318.0 254.0 42 46 22 24 [[277, 541], [590, 1001]] 2.0 7qwk OTHER_EIF2AK4-2_HUMAN OTHER 2.1e-46 164.7 1.0 256.0 256.0 865 866 867 869 871 619 636 640 845 847 846 848.0 925 911 906 905 904 903 902 901 900 803 eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKA Q9P2K8 583 998 1649.0 G41:1701 Type1 Inactive DFGout 17.8239 9.5126 None -134.51, -151.1 -121.46, -46.25 35.17, 27.68 228.21, 155.53 -84.53, 128.11 out-none out 11.5577 Saltbr-none 999.0 HRD-in -76.45, -48.97 72.32, -6.8 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -170.65 APE8-dihe-out -87.38, 8.98 APE8-rot-none 999.0 APE67-dihe-in -67.63, -12.84 -66.2, 0.93 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 13.2821 D848N None None XRAY 2.3 0.214 0.243 A 318.0 245.0 48 46 13 33 [[277, 541], [590, 1001]] 2.0 7qwk OTHER_EIF2AK4-2_HUMAN OTHER 2.1e-46 164.7 1.0 256.0 256.0 865 866 867 869 871 619 636 640 845 847 846 848.0 925 911 906 905 904 903 902 901 900 803 eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKB Q9P2K8 583 998 1649.0 G41:1701 Type1 Inactive DFGout 17.8439 9.3903 None -144.52, -139.04 -156.42, 125.77 -114.71, 16.01 223.02, 149.14 -71.92, 114.82 out-out out 11.8481 Saltbr-out 8.1951 HRD-in -79.04, -54.75 67.92, 8.38 out-out-out SNCooo out-out ActLoopNT-out 14.5345 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -41.73 APE8-dihe-out -76.87, -29.31 APE8-rot-none 999.0 APE67-dihe-in -63.87, -23.61 -70.02, -18.97 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.8685 D848N None None XRAY 2.3 0.214 0.243 B 318.0 249.0 44 46 20 26 [[277, 541], [590, 1001]] 2.0 7qwk OTHER_EIF2AK4-2_HUMAN OTHER 2.1e-46 164.7 1.0 256.0 256.0 865 866 867 869 871 619 636 640 845 847 846 848.0 925 911 906 905 904 903 902 901 900 803 eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKC Q9P2K8 583 1004 1649.0 G41:1701 Type1 Inactive DFGout 17.9422 9.7212 None -140.22, -142.02 -158.37, 117.76 -96.27, -4.59 219.72, 151.65 -71.27, 106.76 out-out out 11.963 Saltbr-out 7.857 HRD-in -88.1, -52.43 58.54, 27.47 out-out-none SNCoon out-none ActLoopNT-out 15.3146 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -59.9 APE8-rot-none 999.0 APE67-dihe-in -67.01, -4.12 -84.11, -11.79 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 D848N None None XRAY 2.3 0.214 0.243 C 318.0 249.0 47 46 16 30 [[277, 541], [590, 1001]] 2.0 7qwk OTHER_EIF2AK4-2_HUMAN OTHER 2.1e-46 164.7 1.0 256.0 256.0 865 866 867 869 871 619 636 640 845 847 846 848.0 925 911 906 905 904 903 902 901 900 803 eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKD Q9P2K8 583 1003 1649.0 G41:1701 Type1 Inactive DFGout 17.7026 9.3216 None -139.27, -135.78 -159.12, 124.73 -118.38, 23.17 221.49, 144.06 -75.45, 126.8 out-out out 11.8336 Saltbr-out 8.4313 HRD-in -88.04, -58.27 56.71, 45.95 out-out-out SNCooo out-out ActLoopNT-out 14.7493 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -86.87 APE8-dihe-out -67.23, -22.9 APE8-rot-none 999.0 APE67-dihe-in -74.1, -19.72 -68.07, -8.44 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 13.5566 D848N None None XRAY 2.3 0.214 0.243 D 318.0 254.0 41 46 19 27 [[277, 541], [590, 1001]] 2.0 7qwk OTHER_EIF2AK4-2_HUMAN OTHER 2.1e-46 164.7 1.0 256.0 256.0 865 866 867 869 871 619 636 640 845 847 846 848.0 925 911 906 905 904 903 902 901 900 803 eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKE Q9P2K8 584 1004 1649.0 G41:1701 Type1 Inactive DFGout 17.7793 9.8216 None -151.76, -141.6 -160.26, 136.01 -98.22, 91.17 239.64, 115.15 -107.96, 84.44 out-none out 11.0819 Saltbr-none 999.0 HRD-in -88.02, -51.01 74.43, -13.48 none-none-none SNCnnn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, 999.0 999.0, 999.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 D848N None None XRAY 2.3 0.214 0.243 E 318.0 241.0 54 46 4 42 [[277, 541], [590, 1001]] 2.0 7qwk OTHER_EIF2AK4-2_HUMAN OTHER 2.1e-46 164.7 1.0 256.0 256.0 865 866 867 869 871 619 636 640 845 847 846 848.0 925 911 906 905 904 903 902 901 900 803 eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKG Q9P2K8 584 1007 1649.0 G41:1701 Type1 Inactive DFGout 18.1915 10.1344 None -152.52, -143.94 -140.15, -46.73 82.87, -54.7 218.3, 133.54 -74.32, 999.0 out-out out 11.6583 Saltbr-out 9.1998 HRD-in -81.42, -58.02 87.03, -25.33 out-out-none SNCoon out-none ActLoopNT-out 6.6179 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -52.87 APE8-rot-none 999.0 APE67-dihe-in -65.85, -22.5 -65.49, -20.84 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 D848N None None XRAY 2.3 0.214 0.243 G 318.0 257.0 41 46 20 26 [[277, 541], [590, 1001]] 2.0 7qwk OTHER_EIF2AK4-2_HUMAN OTHER 2.1e-46 164.7 1.0 256.0 256.0 865 866 867 869 871 619 636 640 845 847 846 848.0 925 911 906 905 904 903 902 901 900 803 eIF-2-alpha kinase GCN2

PDB: 7QWK — OTHER E2AK4_HUMAN

Total number of chains: 8
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 6 75.0% 7QWKD
DFGinter BABtrans 1 12.5% 7QWKH
DFGinter None 1 12.5% 7QWKF
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKH Q9P2K8 584 1006 1649.0 G41:1701 Type1 Inactive DFGinter 8.0462 8.4367 BABtrans -55.61, 130.2 -124.52, 16.67 -106.93, 111.28 188.62, 73.34 126.77, 18.12 out-out out 11.0562 Saltbr-out 7.6256 HRD-in -81.65, -56.1 78.04, -22.14 out-out-out SNCooo out-out ActLoopNT-out 5.2947 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_oooo APE10-dihe-na -63.36, -44.68 APE9-dihe-na -61.4, -37.94 APE8-dihe-out -73.72, -24.45 APE8-rot-none 999.0 APE67-dihe-in -74.17, -2.36 -79.69, -19.77 APE12-dist-out 22.3633 APE11-dist-out 21.0532 APE10-dist-out 23.9535 APE9-dist-out 13.5058 D848N None None XRAY 2.3 0.214 0.243 H 318.0 259.0 38 46 27 19 [[277, 541], [590, 1001]] 2.0 7qwk Homo sapiens OTHER_EIF2AK4-2_HUMAN OTHER 2.1e-46 164.7 1.0 256.0 256.0 865 866 867 869 871 619 636 640 845 847 846 848.0 925 911 906 905 904 903 902 901 900 803 eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKF Q9P2K8 584 1005 1649.0 G41:1701 Type1 Inactive DFGinter 8.0374 8.1815 None -60.18, 141.19 -134.64, 94.13 -155.09, 69.13 206.23, 33.34 148.0, 161.57 out-out out 11.1145 Saltbr-out 8.211 HRD-in -90.54, -49.57 66.47, -5.34 out-out-out SNCooo out-out ActLoopNT-out 6.628 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_oooo APE10-dihe-na 134.32, -54.28 APE9-dihe-na -62.87, -46.85 APE8-dihe-out -62.12, -35.02 APE8-rot-none 999.0 APE67-dihe-in -70.96, -4.61 -71.45, -20.51 APE12-dist-out 23.468 APE11-dist-out 21.7478 APE10-dist-out 24.3155 APE9-dist-out 13.581 D848N None None XRAY 2.3 0.214 0.243 F 318.0 254.0 42 46 22 24 [[277, 541], [590, 1001]] 2.0 7qwk Homo sapiens OTHER_EIF2AK4-2_HUMAN OTHER 2.1e-46 164.7 1.0 256.0 256.0 865 866 867 869 871 619 636 640 845 847 846 848.0 925 911 906 905 904 903 902 901 900 803 eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKA Q9P2K8 583 998 1649.0 G41:1701 Type1 Inactive DFGout 17.8239 9.5126 None -134.51, -151.1 -121.46, -46.25 35.17, 27.68 228.21, 155.53 -84.53, 128.11 out-none out 11.5577 Saltbr-none 999.0 HRD-in -76.45, -48.97 72.32, -6.8 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -170.65 APE8-dihe-out -87.38, 8.98 APE8-rot-none 999.0 APE67-dihe-in -67.63, -12.84 -66.2, 0.93 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 13.2821 D848N None None XRAY 2.3 0.214 0.243 A 318.0 245.0 48 46 13 33 [[277, 541], [590, 1001]] 2.0 7qwk Homo sapiens OTHER_EIF2AK4-2_HUMAN OTHER 2.1e-46 164.7 1.0 256.0 256.0 865 866 867 869 871 619 636 640 845 847 846 848.0 925 911 906 905 904 903 902 901 900 803 eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKB Q9P2K8 583 998 1649.0 G41:1701 Type1 Inactive DFGout 17.8439 9.3903 None -144.52, -139.04 -156.42, 125.77 -114.71, 16.01 223.02, 149.14 -71.92, 114.82 out-out out 11.8481 Saltbr-out 8.1951 HRD-in -79.04, -54.75 67.92, 8.38 out-out-out SNCooo out-out ActLoopNT-out 14.5345 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -41.73 APE8-dihe-out -76.87, -29.31 APE8-rot-none 999.0 APE67-dihe-in -63.87, -23.61 -70.02, -18.97 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.8685 D848N None None XRAY 2.3 0.214 0.243 B 318.0 249.0 44 46 20 26 [[277, 541], [590, 1001]] 2.0 7qwk Homo sapiens OTHER_EIF2AK4-2_HUMAN OTHER 2.1e-46 164.7 1.0 256.0 256.0 865 866 867 869 871 619 636 640 845 847 846 848.0 925 911 906 905 904 903 902 901 900 803 eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKC Q9P2K8 583 1004 1649.0 G41:1701 Type1 Inactive DFGout 17.9422 9.7212 None -140.22, -142.02 -158.37, 117.76 -96.27, -4.59 219.72, 151.65 -71.27, 106.76 out-out out 11.963 Saltbr-out 7.857 HRD-in -88.1, -52.43 58.54, 27.47 out-out-none SNCoon out-none ActLoopNT-out 15.3146 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -59.9 APE8-rot-none 999.0 APE67-dihe-in -67.01, -4.12 -84.11, -11.79 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 D848N None None XRAY 2.3 0.214 0.243 C 318.0 249.0 47 46 16 30 [[277, 541], [590, 1001]] 2.0 7qwk Homo sapiens OTHER_EIF2AK4-2_HUMAN OTHER 2.1e-46 164.7 1.0 256.0 256.0 865 866 867 869 871 619 636 640 845 847 846 848.0 925 911 906 905 904 903 902 901 900 803 eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKD Q9P2K8 583 1003 1649.0 G41:1701 Type1 Inactive DFGout 17.7026 9.3216 None -139.27, -135.78 -159.12, 124.73 -118.38, 23.17 221.49, 144.06 -75.45, 126.8 out-out out 11.8336 Saltbr-out 8.4313 HRD-in -88.04, -58.27 56.71, 45.95 out-out-out SNCooo out-out ActLoopNT-out 14.7493 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -86.87 APE8-dihe-out -67.23, -22.9 APE8-rot-none 999.0 APE67-dihe-in -74.1, -19.72 -68.07, -8.44 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 13.5566 D848N None None XRAY 2.3 0.214 0.243 D 318.0 254.0 41 46 19 27 [[277, 541], [590, 1001]] 2.0 7qwk Homo sapiens OTHER_EIF2AK4-2_HUMAN OTHER 2.1e-46 164.7 1.0 256.0 256.0 865 866 867 869 871 619 636 640 845 847 846 848.0 925 911 906 905 904 903 902 901 900 803 eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKE Q9P2K8 584 1004 1649.0 G41:1701 Type1 Inactive DFGout 17.7793 9.8216 None -151.76, -141.6 -160.26, 136.01 -98.22, 91.17 239.64, 115.15 -107.96, 84.44 out-none out 11.0819 Saltbr-none 999.0 HRD-in -88.02, -51.01 74.43, -13.48 none-none-none SNCnnn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, 999.0 999.0, 999.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 D848N None None XRAY 2.3 0.214 0.243 E 318.0 241.0 54 46 4 42 [[277, 541], [590, 1001]] 2.0 7qwk Homo sapiens OTHER_EIF2AK4-2_HUMAN OTHER 2.1e-46 164.7 1.0 256.0 256.0 865 866 867 869 871 619 636 640 845 847 846 848.0 925 911 906 905 904 903 902 901 900 803 eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKG Q9P2K8 584 1007 1649.0 G41:1701 Type1 Inactive DFGout 18.1915 10.1344 None -152.52, -143.94 -140.15, -46.73 82.87, -54.7 218.3, 133.54 -74.32, 999.0 out-out out 11.6583 Saltbr-out 9.1998 HRD-in -81.42, -58.02 87.03, -25.33 out-out-none SNCoon out-none ActLoopNT-out 6.6179 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -52.87 APE8-rot-none 999.0 APE67-dihe-in -65.85, -22.5 -65.49, -20.84 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 D848N None None XRAY 2.3 0.214 0.243 G 318.0 257.0 41 46 20 26 [[277, 541], [590, 1001]] 2.0 7qwk Homo sapiens OTHER_EIF2AK4-2_HUMAN OTHER 2.1e-46 164.7 1.0 256.0 256.0 865 866 867 869 871 619 636 640 845 847 846 848.0 925 911 906 905 904 903 902 901 900 803 eIF-2-alpha kinase GCN2

PDB: 7QWK — OTHER E2AK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name