Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OTHER | EIF2AK4-2 | E2AK4_HUMAN | 7QWKH | Q9P2K8 | 584 | 1006 | 1649.0 | G41:1701 | Type1 | Inactive | DFGinter | 8.046 | 8.437 | BABtrans | -55.61, 130.2 | -124.52, 16.67 | -106.93, 111.28 | 188.62, 73.34 | 126.77, 18.12 | out-out | out | 11.056 | Saltbr-out | 7.626 | HRD-in | -81.65, -56.1 | 78.04, -22.14 | out-out-out | SNCooo | out-out | ActLoopNT-out | 5.295 | ActLoopCT-out | nonTYR | APEdihe_aaoni | APEdist_oooo | APE10-dihe-na | -63.36, -44.68 | APE9-dihe-na | -61.4, -37.94 | APE8-dihe-out | -73.72, -24.45 | APE8-rot-none | 999.0 | APE67-dihe-in | -74.17, -2.36 | -79.69, -19.77 | APE12-dist-out | 22.363 | APE11-dist-out | 21.053 | APE10-dist-out | 23.953 | APE9-dist-out | 13.506 | D848N | None | None | XRAY | 2.3 | 0.214 | 0.243 | H | 318 | 259 | 38 | 0 | 0 | 19 | [[277, 541], [590, 1001]] | 2.0 | 7qwk | OTHER_EIF2AK4-2_HUMAN | OTHER | 2.1e-46 | 164.7 | 1 | 256 | 256 | 865 | 866 | 867 | 869 | 871 | 619 | 636 | 640 | 845 | 847 | 846 | 848 | 925 | 911 | 906 | 905 | 904 | 903 | 902 | 901 | 900 | 803 | eIF-2-alpha kinase GCN2 |
| OTHER | EIF2AK4-2 | E2AK4_HUMAN | 7QWKF | Q9P2K8 | 584 | 1005 | 1649.0 | G41:1701 | Type1 | Inactive | DFGinter | 8.037 | 8.181 | None | -60.18, 141.19 | -134.64, 94.13 | -155.09, 69.13 | 206.23, 33.34 | 148.0, 161.57 | out-out | out | 11.114 | Saltbr-out | 8.211 | HRD-in | -90.54, -49.57 | 66.47, -5.34 | out-out-out | SNCooo | out-out | ActLoopNT-out | 6.628 | ActLoopCT-out | nonTYR | APEdihe_aaoni | APEdist_oooo | APE10-dihe-na | 134.32, -54.28 | APE9-dihe-na | -62.87, -46.85 | APE8-dihe-out | -62.12, -35.02 | APE8-rot-none | 999.0 | APE67-dihe-in | -70.96, -4.61 | -71.45, -20.51 | APE12-dist-out | 23.468 | APE11-dist-out | 21.748 | APE10-dist-out | 24.316 | APE9-dist-out | 13.581 | D848N | None | None | XRAY | 2.3 | 0.214 | 0.243 | F | 318 | 254 | 42 | 0 | 0 | 24 | [[277, 541], [590, 1001]] | 2.0 | 7qwk | OTHER_EIF2AK4-2_HUMAN | OTHER | 2.1e-46 | 164.7 | 1 | 256 | 256 | 865 | 866 | 867 | 869 | 871 | 619 | 636 | 640 | 845 | 847 | 846 | 848 | 925 | 911 | 906 | 905 | 904 | 903 | 902 | 901 | 900 | 803 | eIF-2-alpha kinase GCN2 |
| OTHER | EIF2AK4-2 | E2AK4_HUMAN | 7QWKA | Q9P2K8 | 583 | 998 | 1649.0 | G41:1701 | Type1 | Inactive | DFGout | 17.824 | 9.513 | None | -134.51, -151.1 | -121.46, -46.25 | 35.17, 27.68 | 228.21, 155.53 | -84.53, 128.11 | out-none | out | 11.558 | Saltbr-none | 999.0 | HRD-in | -76.45, -48.97 | 72.32, -6.8 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aaoni | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, -170.65 | APE8-dihe-out | -87.38, 8.98 | APE8-rot-none | 999.0 | APE67-dihe-in | -67.63, -12.84 | -66.2, 0.93 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 13.282 | D848N | None | None | XRAY | 2.3 | 0.214 | 0.243 | A | 318 | 245 | 48 | 0 | 0 | 33 | [[277, 541], [590, 1001]] | 2.0 | 7qwk | OTHER_EIF2AK4-2_HUMAN | OTHER | 2.1e-46 | 164.7 | 1 | 256 | 256 | 865 | 866 | 867 | 869 | 871 | 619 | 636 | 640 | 845 | 847 | 846 | 848 | 925 | 911 | 906 | 905 | 904 | 903 | 902 | 901 | 900 | 803 | eIF-2-alpha kinase GCN2 |
| OTHER | EIF2AK4-2 | E2AK4_HUMAN | 7QWKB | Q9P2K8 | 583 | 998 | 1649.0 | G41:1701 | Type1 | Inactive | DFGout | 17.844 | 9.39 | None | -144.52, -139.04 | -156.42, 125.77 | -114.71, 16.01 | 223.02, 149.14 | -71.92, 114.82 | out-out | out | 11.848 | Saltbr-out | 8.195 | HRD-in | -79.04, -54.75 | 67.92, 8.38 | out-out-out | SNCooo | out-out | ActLoopNT-out | 14.534 | ActLoopCT-out | nonTYR | APEdihe_aaoni | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, -41.73 | APE8-dihe-out | -76.87, -29.31 | APE8-rot-none | 999.0 | APE67-dihe-in | -63.87, -23.61 | -70.02, -18.97 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 12.868 | D848N | None | None | XRAY | 2.3 | 0.214 | 0.243 | B | 318 | 249 | 44 | 0 | 0 | 26 | [[277, 541], [590, 1001]] | 2.0 | 7qwk | OTHER_EIF2AK4-2_HUMAN | OTHER | 2.1e-46 | 164.7 | 1 | 256 | 256 | 865 | 866 | 867 | 869 | 871 | 619 | 636 | 640 | 845 | 847 | 846 | 848 | 925 | 911 | 906 | 905 | 904 | 903 | 902 | 901 | 900 | 803 | eIF-2-alpha kinase GCN2 |
| OTHER | EIF2AK4-2 | E2AK4_HUMAN | 7QWKC | Q9P2K8 | 583 | 1004 | 1649.0 | G41:1701 | Type1 | Inactive | DFGout | 17.942 | 9.721 | None | -140.22, -142.02 | -158.37, 117.76 | -96.27, -4.59 | 219.72, 151.65 | -71.27, 106.76 | out-out | out | 11.963 | Saltbr-out | 7.857 | HRD-in | -88.1, -52.43 | 58.54, 27.47 | out-out-none | SNCoon | out-none | ActLoopNT-out | 15.315 | ActLoopCT-none | nonTYR | APEdihe_aanni | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, -59.9 | APE8-rot-none | 999.0 | APE67-dihe-in | -67.01, -4.12 | -84.11, -11.79 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | D848N | None | None | XRAY | 2.3 | 0.214 | 0.243 | C | 318 | 249 | 47 | 0 | 0 | 30 | [[277, 541], [590, 1001]] | 2.0 | 7qwk | OTHER_EIF2AK4-2_HUMAN | OTHER | 2.1e-46 | 164.7 | 1 | 256 | 256 | 865 | 866 | 867 | 869 | 871 | 619 | 636 | 640 | 845 | 847 | 846 | 848 | 925 | 911 | 906 | 905 | 904 | 903 | 902 | 901 | 900 | 803 | eIF-2-alpha kinase GCN2 |
| OTHER | EIF2AK4-2 | E2AK4_HUMAN | 7QWKD | Q9P2K8 | 583 | 1003 | 1649.0 | G41:1701 | Type1 | Inactive | DFGout | 17.703 | 9.322 | None | -139.27, -135.78 | -159.12, 124.73 | -118.38, 23.17 | 221.49, 144.06 | -75.45, 126.8 | out-out | out | 11.834 | Saltbr-out | 8.431 | HRD-in | -88.04, -58.27 | 56.71, 45.95 | out-out-out | SNCooo | out-out | ActLoopNT-out | 14.749 | ActLoopCT-out | nonTYR | APEdihe_aaoni | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, -86.87 | APE8-dihe-out | -67.23, -22.9 | APE8-rot-none | 999.0 | APE67-dihe-in | -74.1, -19.72 | -68.07, -8.44 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 13.557 | D848N | None | None | XRAY | 2.3 | 0.214 | 0.243 | D | 318 | 254 | 41 | 0 | 0 | 27 | [[277, 541], [590, 1001]] | 2.0 | 7qwk | OTHER_EIF2AK4-2_HUMAN | OTHER | 2.1e-46 | 164.7 | 1 | 256 | 256 | 865 | 866 | 867 | 869 | 871 | 619 | 636 | 640 | 845 | 847 | 846 | 848 | 925 | 911 | 906 | 905 | 904 | 903 | 902 | 901 | 900 | 803 | eIF-2-alpha kinase GCN2 |
| OTHER | EIF2AK4-2 | E2AK4_HUMAN | 7QWKE | Q9P2K8 | 584 | 1004 | 1649.0 | G41:1701 | Type1 | Inactive | DFGout | 17.779 | 9.822 | None | -151.76, -141.6 | -160.26, 136.01 | -98.22, 91.17 | 239.64, 115.15 | -107.96, 84.44 | out-none | out | 11.082 | Saltbr-none | 999.0 | HRD-in | -88.02, -51.01 | 74.43, -13.48 | none-none-none | SNCnnn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | 999.0, 999.0 | 999.0, 999.0 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | D848N | None | None | XRAY | 2.3 | 0.214 | 0.243 | E | 318 | 241 | 54 | 0 | 0 | 42 | [[277, 541], [590, 1001]] | 2.0 | 7qwk | OTHER_EIF2AK4-2_HUMAN | OTHER | 2.1e-46 | 164.7 | 1 | 256 | 256 | 865 | 866 | 867 | 869 | 871 | 619 | 636 | 640 | 845 | 847 | 846 | 848 | 925 | 911 | 906 | 905 | 904 | 903 | 902 | 901 | 900 | 803 | eIF-2-alpha kinase GCN2 |
| OTHER | EIF2AK4-2 | E2AK4_HUMAN | 7QWKG | Q9P2K8 | 584 | 1007 | 1649.0 | G41:1701 | Type1 | Inactive | DFGout | 18.192 | 10.134 | None | -152.52, -143.94 | -140.15, -46.73 | 82.87, -54.7 | 218.3, 133.54 | -74.32, 999.0 | out-out | out | 11.658 | Saltbr-out | 9.2 | HRD-in | -81.42, -58.02 | 87.03, -25.33 | out-out-none | SNCoon | out-none | ActLoopNT-out | 6.618 | ActLoopCT-none | nonTYR | APEdihe_aanni | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, -52.87 | APE8-rot-none | 999.0 | APE67-dihe-in | -65.85, -22.5 | -65.49, -20.84 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | D848N | None | None | XRAY | 2.3 | 0.214 | 0.243 | G | 318 | 257 | 41 | 0 | 0 | 26 | [[277, 541], [590, 1001]] | 2.0 | 7qwk | OTHER_EIF2AK4-2_HUMAN | OTHER | 2.1e-46 | 164.7 | 1 | 256 | 256 | 865 | 866 | 867 | 869 | 871 | 619 | 636 | 640 | 845 | 847 | 846 | 848 | 925 | 911 | 906 | 905 | 904 | 903 | 902 | 901 | 900 | 803 | eIF-2-alpha kinase GCN2 |
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OTHER | EIF2AK4-2 | E2AK4_HUMAN | 7QWKH | Q9P2K8 | 584 | 1006 | 1649.0 | G41:1701 | Type1 | Inactive | DFGinter | 8.046 | 8.437 | BABtrans | -55.61, 130.2 | -124.52, 16.67 | -106.93, 111.28 | 188.62, 73.34 | 126.77, 18.12 | out-out | out | 11.056 | Saltbr-out | 7.626 | HRD-in | -81.65, -56.1 | 78.04, -22.14 | out-out-out | SNCooo | out-out | ActLoopNT-out | 5.295 | ActLoopCT-out | nonTYR | APEdihe_aaoni | APEdist_oooo | APE10-dihe-na | -63.36, -44.68 | APE9-dihe-na | -61.4, -37.94 | APE8-dihe-out | -73.72, -24.45 | APE8-rot-none | 999.0 | APE67-dihe-in | -74.17, -2.36 | -79.69, -19.77 | APE12-dist-out | 22.363 | APE11-dist-out | 21.053 | APE10-dist-out | 23.953 | APE9-dist-out | 13.506 | D848N | None | None | XRAY | 2.3 | 0.214 | 0.243 | H | 318 | 259 | 38 | 0 | 0 | 19 | [[277, 541], [590, 1001]] | 2.0 | 7qwk | Homo sapiens | OTHER_EIF2AK4-2_HUMAN | OTHER | 2.1e-46 | 164.7 | 1 | 256 | 256 | 865 | 866 | 867 | 869 | 871 | 619 | 636 | 640 | 845 | 847 | 846 | 848 | 925 | 911 | 906 | 905 | 904 | 903 | 902 | 901 | 900 | 803 | eIF-2-alpha kinase GCN2 |
| OTHER | EIF2AK4-2 | E2AK4_HUMAN | 7QWKF | Q9P2K8 | 584 | 1005 | 1649.0 | G41:1701 | Type1 | Inactive | DFGinter | 8.037 | 8.181 | None | -60.18, 141.19 | -134.64, 94.13 | -155.09, 69.13 | 206.23, 33.34 | 148.0, 161.57 | out-out | out | 11.114 | Saltbr-out | 8.211 | HRD-in | -90.54, -49.57 | 66.47, -5.34 | out-out-out | SNCooo | out-out | ActLoopNT-out | 6.628 | ActLoopCT-out | nonTYR | APEdihe_aaoni | APEdist_oooo | APE10-dihe-na | 134.32, -54.28 | APE9-dihe-na | -62.87, -46.85 | APE8-dihe-out | -62.12, -35.02 | APE8-rot-none | 999.0 | APE67-dihe-in | -70.96, -4.61 | -71.45, -20.51 | APE12-dist-out | 23.468 | APE11-dist-out | 21.748 | APE10-dist-out | 24.316 | APE9-dist-out | 13.581 | D848N | None | None | XRAY | 2.3 | 0.214 | 0.243 | F | 318 | 254 | 42 | 0 | 0 | 24 | [[277, 541], [590, 1001]] | 2.0 | 7qwk | Homo sapiens | OTHER_EIF2AK4-2_HUMAN | OTHER | 2.1e-46 | 164.7 | 1 | 256 | 256 | 865 | 866 | 867 | 869 | 871 | 619 | 636 | 640 | 845 | 847 | 846 | 848 | 925 | 911 | 906 | 905 | 904 | 903 | 902 | 901 | 900 | 803 | eIF-2-alpha kinase GCN2 |
| OTHER | EIF2AK4-2 | E2AK4_HUMAN | 7QWKA | Q9P2K8 | 583 | 998 | 1649.0 | G41:1701 | Type1 | Inactive | DFGout | 17.824 | 9.513 | None | -134.51, -151.1 | -121.46, -46.25 | 35.17, 27.68 | 228.21, 155.53 | -84.53, 128.11 | out-none | out | 11.558 | Saltbr-none | 999.0 | HRD-in | -76.45, -48.97 | 72.32, -6.8 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aaoni | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, -170.65 | APE8-dihe-out | -87.38, 8.98 | APE8-rot-none | 999.0 | APE67-dihe-in | -67.63, -12.84 | -66.2, 0.93 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 13.282 | D848N | None | None | XRAY | 2.3 | 0.214 | 0.243 | A | 318 | 245 | 48 | 0 | 0 | 33 | [[277, 541], [590, 1001]] | 2.0 | 7qwk | Homo sapiens | OTHER_EIF2AK4-2_HUMAN | OTHER | 2.1e-46 | 164.7 | 1 | 256 | 256 | 865 | 866 | 867 | 869 | 871 | 619 | 636 | 640 | 845 | 847 | 846 | 848 | 925 | 911 | 906 | 905 | 904 | 903 | 902 | 901 | 900 | 803 | eIF-2-alpha kinase GCN2 |
| OTHER | EIF2AK4-2 | E2AK4_HUMAN | 7QWKB | Q9P2K8 | 583 | 998 | 1649.0 | G41:1701 | Type1 | Inactive | DFGout | 17.844 | 9.39 | None | -144.52, -139.04 | -156.42, 125.77 | -114.71, 16.01 | 223.02, 149.14 | -71.92, 114.82 | out-out | out | 11.848 | Saltbr-out | 8.195 | HRD-in | -79.04, -54.75 | 67.92, 8.38 | out-out-out | SNCooo | out-out | ActLoopNT-out | 14.534 | ActLoopCT-out | nonTYR | APEdihe_aaoni | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, -41.73 | APE8-dihe-out | -76.87, -29.31 | APE8-rot-none | 999.0 | APE67-dihe-in | -63.87, -23.61 | -70.02, -18.97 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 12.868 | D848N | None | None | XRAY | 2.3 | 0.214 | 0.243 | B | 318 | 249 | 44 | 0 | 0 | 26 | [[277, 541], [590, 1001]] | 2.0 | 7qwk | Homo sapiens | OTHER_EIF2AK4-2_HUMAN | OTHER | 2.1e-46 | 164.7 | 1 | 256 | 256 | 865 | 866 | 867 | 869 | 871 | 619 | 636 | 640 | 845 | 847 | 846 | 848 | 925 | 911 | 906 | 905 | 904 | 903 | 902 | 901 | 900 | 803 | eIF-2-alpha kinase GCN2 |
| OTHER | EIF2AK4-2 | E2AK4_HUMAN | 7QWKC | Q9P2K8 | 583 | 1004 | 1649.0 | G41:1701 | Type1 | Inactive | DFGout | 17.942 | 9.721 | None | -140.22, -142.02 | -158.37, 117.76 | -96.27, -4.59 | 219.72, 151.65 | -71.27, 106.76 | out-out | out | 11.963 | Saltbr-out | 7.857 | HRD-in | -88.1, -52.43 | 58.54, 27.47 | out-out-none | SNCoon | out-none | ActLoopNT-out | 15.315 | ActLoopCT-none | nonTYR | APEdihe_aanni | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, -59.9 | APE8-rot-none | 999.0 | APE67-dihe-in | -67.01, -4.12 | -84.11, -11.79 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | D848N | None | None | XRAY | 2.3 | 0.214 | 0.243 | C | 318 | 249 | 47 | 0 | 0 | 30 | [[277, 541], [590, 1001]] | 2.0 | 7qwk | Homo sapiens | OTHER_EIF2AK4-2_HUMAN | OTHER | 2.1e-46 | 164.7 | 1 | 256 | 256 | 865 | 866 | 867 | 869 | 871 | 619 | 636 | 640 | 845 | 847 | 846 | 848 | 925 | 911 | 906 | 905 | 904 | 903 | 902 | 901 | 900 | 803 | eIF-2-alpha kinase GCN2 |
| OTHER | EIF2AK4-2 | E2AK4_HUMAN | 7QWKD | Q9P2K8 | 583 | 1003 | 1649.0 | G41:1701 | Type1 | Inactive | DFGout | 17.703 | 9.322 | None | -139.27, -135.78 | -159.12, 124.73 | -118.38, 23.17 | 221.49, 144.06 | -75.45, 126.8 | out-out | out | 11.834 | Saltbr-out | 8.431 | HRD-in | -88.04, -58.27 | 56.71, 45.95 | out-out-out | SNCooo | out-out | ActLoopNT-out | 14.749 | ActLoopCT-out | nonTYR | APEdihe_aaoni | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, -86.87 | APE8-dihe-out | -67.23, -22.9 | APE8-rot-none | 999.0 | APE67-dihe-in | -74.1, -19.72 | -68.07, -8.44 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 13.557 | D848N | None | None | XRAY | 2.3 | 0.214 | 0.243 | D | 318 | 254 | 41 | 0 | 0 | 27 | [[277, 541], [590, 1001]] | 2.0 | 7qwk | Homo sapiens | OTHER_EIF2AK4-2_HUMAN | OTHER | 2.1e-46 | 164.7 | 1 | 256 | 256 | 865 | 866 | 867 | 869 | 871 | 619 | 636 | 640 | 845 | 847 | 846 | 848 | 925 | 911 | 906 | 905 | 904 | 903 | 902 | 901 | 900 | 803 | eIF-2-alpha kinase GCN2 |
| OTHER | EIF2AK4-2 | E2AK4_HUMAN | 7QWKE | Q9P2K8 | 584 | 1004 | 1649.0 | G41:1701 | Type1 | Inactive | DFGout | 17.779 | 9.822 | None | -151.76, -141.6 | -160.26, 136.01 | -98.22, 91.17 | 239.64, 115.15 | -107.96, 84.44 | out-none | out | 11.082 | Saltbr-none | 999.0 | HRD-in | -88.02, -51.01 | 74.43, -13.48 | none-none-none | SNCnnn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | 999.0, 999.0 | 999.0, 999.0 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | D848N | None | None | XRAY | 2.3 | 0.214 | 0.243 | E | 318 | 241 | 54 | 0 | 0 | 42 | [[277, 541], [590, 1001]] | 2.0 | 7qwk | Homo sapiens | OTHER_EIF2AK4-2_HUMAN | OTHER | 2.1e-46 | 164.7 | 1 | 256 | 256 | 865 | 866 | 867 | 869 | 871 | 619 | 636 | 640 | 845 | 847 | 846 | 848 | 925 | 911 | 906 | 905 | 904 | 903 | 902 | 901 | 900 | 803 | eIF-2-alpha kinase GCN2 |
| OTHER | EIF2AK4-2 | E2AK4_HUMAN | 7QWKG | Q9P2K8 | 584 | 1007 | 1649.0 | G41:1701 | Type1 | Inactive | DFGout | 18.192 | 10.134 | None | -152.52, -143.94 | -140.15, -46.73 | 82.87, -54.7 | 218.3, 133.54 | -74.32, 999.0 | out-out | out | 11.658 | Saltbr-out | 9.2 | HRD-in | -81.42, -58.02 | 87.03, -25.33 | out-out-none | SNCoon | out-none | ActLoopNT-out | 6.618 | ActLoopCT-none | nonTYR | APEdihe_aanni | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, -52.87 | APE8-rot-none | 999.0 | APE67-dihe-in | -65.85, -22.5 | -65.49, -20.84 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | D848N | None | None | XRAY | 2.3 | 0.214 | 0.243 | G | 318 | 257 | 41 | 0 | 0 | 26 | [[277, 541], [590, 1001]] | 2.0 | 7qwk | Homo sapiens | OTHER_EIF2AK4-2_HUMAN | OTHER | 2.1e-46 | 164.7 | 1 | 256 | 256 | 865 | 866 | 867 | 869 | 871 | 619 | 636 | 640 | 845 | 847 | 846 | 848 | 925 | 911 | 906 | 905 | 904 | 903 | 902 | 901 | 900 | 803 | eIF-2-alpha kinase GCN2 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|