PDB: 4IZ5 — CMGC MK01_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 4IZ5A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_HUMAN 4IZ5A P28482 11 357 360.0 ADP:900 ATPlike Inactive DFGin 6.5744 16.2257 BLAminus -133.03, 170.47 61.68, 96.87 -113.24, 29.97 280.98, 72.88 -75.05, -15.97 in-out in 8.9431 Saltbr-out 6.3365 HRD-in -70.37, -54.19 76.22, -6.05 out-in-out SNCoio in-out ActLoopNT-in 2.8045 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooo APE10-dihe-na -135.59, 107.64 APE9-dihe-na -86.59, -36.52 APE8-dihe-in -63.86, 130.93 APE8-rot-in 305.07 APE67-dihe-in -64.33, -26.99 -124.19, 30.24 APE12-dist-in 10.0117 APE11-dist-out 7.082 APE10-dist-out 8.2491 APE9-dist-out 10.5104 T185E None None XRAY 3.19 0.245 0.292 A 356.0 347.0 0 31 31 0 [[25, 313]] 1.0 4iz5 CMGC_MAPK1_HUMAN CMGC 2.5e-85 292.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4IZ5B P28482 11 357 360.0 ADP:900 ATPlike Inactive DFGin 6.6142 16.236 BLAminus -130.77, 169.05 63.18, 96.88 -112.33, 27.86 280.9, 72.0 -73.48, -17.21 in-out in 8.9516 Saltbr-out 6.2842 HRD-in -71.55, -52.24 74.21, -4.59 out-in-out SNCoio in-out ActLoopNT-in 2.846 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooo APE10-dihe-na -135.05, 108.67 APE9-dihe-na -88.18, -35.19 APE8-dihe-in -65.83, 129.75 APE8-rot-in 303.93 APE67-dihe-in -64.9, -24.28 -122.7, 29.42 APE12-dist-in 10.0315 APE11-dist-out 7.0852 APE10-dist-out 8.2498 APE9-dist-out 10.5027 T185E None None XRAY 3.19 0.245 0.292 B 356.0 347.0 0 31 31 0 [[25, 313]] 1.0 4iz5 CMGC_MAPK1_HUMAN CMGC 2.5e-85 292.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4IZ5C P28482 11 357 360.0 ADP:900 ATPlike Inactive DFGin 6.6044 16.2316 BLAminus -131.01, 170.44 62.04, 96.83 -112.78, 28.94 280.74, 73.4 -74.17, -17.63 in-out in 8.9448 Saltbr-out 6.3598 HRD-in -72.88, -51.67 75.48, -6.0 out-in-out SNCoio in-out ActLoopNT-in 2.8678 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooo APE10-dihe-na -133.99, 108.02 APE9-dihe-na -87.46, -36.5 APE8-dihe-in -65.77, 130.32 APE8-rot-in 303.26 APE67-dihe-in -66.37, -24.82 -122.99, 29.53 APE12-dist-in 10.0145 APE11-dist-out 7.0682 APE10-dist-out 8.2202 APE9-dist-out 10.4967 T185E None None XRAY 3.19 0.245 0.292 C 356.0 347.0 0 31 31 0 [[25, 313]] 1.0 4iz5 CMGC_MAPK1_HUMAN CMGC 2.5e-85 292.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4IZ5D P28482 11 357 360.0 ADP:900 ATPlike Inactive DFGin 6.6009 16.2317 BLAminus -131.94, 170.02 62.64, 97.08 -112.75, 27.73 280.79, 72.08 -72.23, -17.73 in-out in 8.9604 Saltbr-out 6.3214 HRD-in -71.89, -53.7 75.24, -4.58 out-in-out SNCoio in-out ActLoopNT-in 2.8465 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooo APE10-dihe-na -135.09, 108.16 APE9-dihe-na -88.37, -35.4 APE8-dihe-in -66.59, 130.93 APE8-rot-in 303.88 APE67-dihe-in -65.41, -25.44 -123.75, 30.53 APE12-dist-in 10.0122 APE11-dist-out 7.0881 APE10-dist-out 8.224 APE9-dist-out 10.4605 T185E None None XRAY 3.19 0.245 0.292 D 356.0 347.0 0 31 31 0 [[25, 313]] 1.0 4iz5 CMGC_MAPK1_HUMAN CMGC 2.5e-85 292.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1

PDB: 4IZ5 — CMGC MK01_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 4IZ5A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_HUMAN 4IZ5A P28482 11 357 360.0 ADP:900 ATPlike Inactive DFGin 6.5744 16.2257 BLAminus -133.03, 170.47 61.68, 96.87 -113.24, 29.97 280.98, 72.88 -75.05, -15.97 in-out in 8.9431 Saltbr-out 6.3365 HRD-in -70.37, -54.19 76.22, -6.05 out-in-out SNCoio in-out ActLoopNT-in 2.8045 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooo APE10-dihe-na -135.59, 107.64 APE9-dihe-na -86.59, -36.52 APE8-dihe-in -63.86, 130.93 APE8-rot-in 305.07 APE67-dihe-in -64.33, -26.99 -124.19, 30.24 APE12-dist-in 10.0117 APE11-dist-out 7.082 APE10-dist-out 8.2491 APE9-dist-out 10.5104 T185E None None XRAY 3.19 0.245 0.292 A 356.0 347.0 0 31 31 0 [[25, 313]] 1.0 4iz5 Homo sapiens CMGC_MAPK1_HUMAN CMGC 2.5e-85 292.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4IZ5B P28482 11 357 360.0 ADP:900 ATPlike Inactive DFGin 6.6142 16.236 BLAminus -130.77, 169.05 63.18, 96.88 -112.33, 27.86 280.9, 72.0 -73.48, -17.21 in-out in 8.9516 Saltbr-out 6.2842 HRD-in -71.55, -52.24 74.21, -4.59 out-in-out SNCoio in-out ActLoopNT-in 2.846 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooo APE10-dihe-na -135.05, 108.67 APE9-dihe-na -88.18, -35.19 APE8-dihe-in -65.83, 129.75 APE8-rot-in 303.93 APE67-dihe-in -64.9, -24.28 -122.7, 29.42 APE12-dist-in 10.0315 APE11-dist-out 7.0852 APE10-dist-out 8.2498 APE9-dist-out 10.5027 T185E None None XRAY 3.19 0.245 0.292 B 356.0 347.0 0 31 31 0 [[25, 313]] 1.0 4iz5 Homo sapiens CMGC_MAPK1_HUMAN CMGC 2.5e-85 292.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4IZ5C P28482 11 357 360.0 ADP:900 ATPlike Inactive DFGin 6.6044 16.2316 BLAminus -131.01, 170.44 62.04, 96.83 -112.78, 28.94 280.74, 73.4 -74.17, -17.63 in-out in 8.9448 Saltbr-out 6.3598 HRD-in -72.88, -51.67 75.48, -6.0 out-in-out SNCoio in-out ActLoopNT-in 2.8678 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooo APE10-dihe-na -133.99, 108.02 APE9-dihe-na -87.46, -36.5 APE8-dihe-in -65.77, 130.32 APE8-rot-in 303.26 APE67-dihe-in -66.37, -24.82 -122.99, 29.53 APE12-dist-in 10.0145 APE11-dist-out 7.0682 APE10-dist-out 8.2202 APE9-dist-out 10.4967 T185E None None XRAY 3.19 0.245 0.292 C 356.0 347.0 0 31 31 0 [[25, 313]] 1.0 4iz5 Homo sapiens CMGC_MAPK1_HUMAN CMGC 2.5e-85 292.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4IZ5D P28482 11 357 360.0 ADP:900 ATPlike Inactive DFGin 6.6009 16.2317 BLAminus -131.94, 170.02 62.64, 97.08 -112.75, 27.73 280.79, 72.08 -72.23, -17.73 in-out in 8.9604 Saltbr-out 6.3214 HRD-in -71.89, -53.7 75.24, -4.58 out-in-out SNCoio in-out ActLoopNT-in 2.8465 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooo APE10-dihe-na -135.09, 108.16 APE9-dihe-na -88.37, -35.4 APE8-dihe-in -66.59, 130.93 APE8-rot-in 303.88 APE67-dihe-in -65.41, -25.44 -123.75, 30.53 APE12-dist-in 10.0122 APE11-dist-out 7.0881 APE10-dist-out 8.224 APE9-dist-out 10.4605 T185E None None XRAY 3.19 0.245 0.292 D 356.0 347.0 0 31 31 0 [[25, 313]] 1.0 4iz5 Homo sapiens CMGC_MAPK1_HUMAN CMGC 2.5e-85 292.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1

PDB: 4IZ5 — CMGC MK01_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name