Ligand: XL6

Total number of chains: 5
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 5 100.0% 6NVHA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR FGFR1 FGFR1_HUMAN 6NVLA 2.7 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao XL6 Type1.5_Back 463 - 765 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6NVLB 2.7 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan XL6 Type1.5_Back 461 - 761 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6NVLC 2.7 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan XL6 Type1.5_Back 465 - 761 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6NVLD 2.7 Inactive DFGin‑BLAplus in-none none-out TYR APEdihe_iioai APEdist_aaao XL6 Type1.5_Back 471 - 762 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR4 FGFR4_HUMAN 6NVHA 1.9 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_nniai APEdist_aaao XL6 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4

Ligand: XL6

Total number of chains: 5
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 5 100.0% 6NVHA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR FGFR1 FGFR1_HUMAN 6NVLA 2.7 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao XL6 Type1.5_Back 463 - 765 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6NVLB 2.7 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan XL6 Type1.5_Back 461 - 761 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6NVLC 2.7 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan XL6 Type1.5_Back 465 - 761 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6NVLD 2.7 Inactive DFGin‑BLAplus in-none none-out TYR APEdihe_iioai APEdist_aaao XL6 Type1.5_Back 471 - 762 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6NVHA 1.9 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_nniai APEdist_aaao XL6 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4 Homo sapiens

Ligand: XL6

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism