Ligand: XL6

Total number of chains: 5
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 5 100.0% 6NVHA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR1 FGFR1_HUMAN 6NVLA P11362 463 765 822.0 XL6:802 Type1.5_Back Inactive DFGin 5.1279 13.3113 BLAplus -119.52, 157.53 59.31, 34.82 -84.42, -16.16 59.33, 82.45 -101.42, 33.52 in-in in 7.5898 Saltbr-in 2.8655 HRD-in -75.42, -53.52 80.47, -2.41 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -74.68, 147.97 APE9-dihe-in -112.42, 91.75 APE8-dihe-out -47.21, -34.96 APE8-rot-na 327.61 APE67-dihe-in -66.06, -15.18 -49.22, -31.67 APE12-dist-na 17.2866 APE11-dist-na 20.5601 APE10-dist-na 17.1824 APE9-dist-out 11.6245 C584S None None XRAY 2.7 0.215 0.263 A 309.0 280.0 23 30 21 9 [[478, 756]] 1.0 6nvl TYR_FGFR1_HUMAN TYR 2.1e-104 354.4 1.0 260.0 260.0 640 641 642 644 646 514 531 535 620 622 621 623.0 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6NVLB P11362 461 761 822.0 XL6:802 Type1.5_Back Inactive DFGin 5.2902 13.112 BLAplus -110.71, 154.52 49.9, 58.02 -103.43, -14.13 54.73, 82.29 -99.41, 13.49 in-in in 7.6235 Saltbr-in 3.0252 HRD-in -62.36, -64.19 100.95, -30.38 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -38.63 APE8-rot-na 324.79 APE67-dihe-in -73.34, -7.41 -51.06, -32.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 C584S None None XRAY 2.7 0.215 0.263 B 309.0 263.0 38 30 12 18 [[478, 756]] 1.0 6nvl TYR_FGFR1_HUMAN TYR 2.1e-104 354.4 1.0 260.0 260.0 640 641 642 644 646 514 531 535 620 622 621 623.0 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6NVLC P11362 465 761 822.0 XL6:801 Type1.5_Back Inactive DFGin 5.3955 13.3962 BLAplus -121.16, 162.24 42.87, 55.81 -103.48, -8.54 57.38, 81.17 -97.02, -26.48 in-in in 7.522 Saltbr-in 3.1539 HRD-in -69.09, -49.97 76.47, -2.8 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -35.16 APE8-rot-na 328.72 APE67-dihe-in -78.06, -0.48 -64.76, -24.4 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 C584S None None XRAY 2.7 0.215 0.263 C 309.0 265.0 32 30 21 9 [[478, 756]] 1.0 6nvl TYR_FGFR1_HUMAN TYR 2.1e-104 354.4 1.0 260.0 260.0 640 641 642 644 646 514 531 535 620 622 621 623.0 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6NVLD P11362 471 762 822.0 XL6:804 Type1.5_Back Inactive DFGin 5.1576 13.3104 BLAplus -117.28, 161.88 52.71, 45.04 -93.07, -6.01 60.08, 84.31 -96.46, -42.94 in-none in 7.3629 Saltbr-none 999.0 HRD-in -74.01, -57.04 84.17, -3.83 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -97.3, 154.56 APE9-dihe-in -112.92, 85.91 APE8-dihe-out -57.48, -12.84 APE8-rot-na 334.14 APE67-dihe-in -78.36, -8.15 -65.38, -24.93 APE12-dist-na 16.4701 APE11-dist-na 19.4008 APE10-dist-na 16.585 APE9-dist-out 11.3348 C584S None None XRAY 2.7 0.215 0.263 D 309.0 269.0 23 30 21 9 [[478, 756]] 1.0 6nvl TYR_FGFR1_HUMAN TYR 2.1e-104 354.4 1.0 260.0 260.0 640 641 642 644 646 514 531 535 620 622 621 623.0 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR4 FGFR4_HUMAN 6NVHA P22455 453 750 802.0 XL6:60803 Type1.5_Back Inactive DFGin 5.2448 13.4006 BLAplus -105.65, 156.33 59.41, 40.23 -87.91, -7.9 56.0, 80.86 -110.13, 11.2 in-in in 7.6449 Saltbr-in 2.9087 HRD-in -72.21, -55.48 85.67, -17.85 in-out-out SNCioo out-out ActLoopNT-out 8.8817 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 119.32 APE8-dihe-in -79.08, 68.56 APE8-rot-na 34.44 APE67-dihe-in -72.6, -11.42 -66.3, -25.11 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 9.0923 None None None XRAY 1.9 0.213 0.234 A 300.0 271.0 18 30 15 15 [[467, 745]] 1.0 6nvh TYR_FGFR4_HUMAN TYR 8e-101 342.6 1.0 261.0 261.0 629 630 631 633 635 503 520 524 609 611 610 612.0 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4

Ligand: XL6

Total number of chains: 5
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 5 100.0% 6NVHA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR1 FGFR1_HUMAN 6NVLA P11362 463 765 822.0 XL6:802 Type1.5_Back Inactive DFGin 5.1279 13.3113 BLAplus -119.52, 157.53 59.31, 34.82 -84.42, -16.16 59.33, 82.45 -101.42, 33.52 in-in in 7.5898 Saltbr-in 2.8655 HRD-in -75.42, -53.52 80.47, -2.41 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -74.68, 147.97 APE9-dihe-in -112.42, 91.75 APE8-dihe-out -47.21, -34.96 APE8-rot-na 327.61 APE67-dihe-in -66.06, -15.18 -49.22, -31.67 APE12-dist-na 17.2866 APE11-dist-na 20.5601 APE10-dist-na 17.1824 APE9-dist-out 11.6245 C584S None None XRAY 2.7 0.215 0.263 A 309.0 280.0 23 30 21 9 [[478, 756]] 1.0 6nvl Homo sapiens TYR_FGFR1_HUMAN TYR 2.1e-104 354.4 1.0 260.0 260.0 640 641 642 644 646 514 531 535 620 622 621 623.0 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6NVLB P11362 461 761 822.0 XL6:802 Type1.5_Back Inactive DFGin 5.2902 13.112 BLAplus -110.71, 154.52 49.9, 58.02 -103.43, -14.13 54.73, 82.29 -99.41, 13.49 in-in in 7.6235 Saltbr-in 3.0252 HRD-in -62.36, -64.19 100.95, -30.38 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -38.63 APE8-rot-na 324.79 APE67-dihe-in -73.34, -7.41 -51.06, -32.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 C584S None None XRAY 2.7 0.215 0.263 B 309.0 263.0 38 30 12 18 [[478, 756]] 1.0 6nvl Homo sapiens TYR_FGFR1_HUMAN TYR 2.1e-104 354.4 1.0 260.0 260.0 640 641 642 644 646 514 531 535 620 622 621 623.0 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6NVLC P11362 465 761 822.0 XL6:801 Type1.5_Back Inactive DFGin 5.3955 13.3962 BLAplus -121.16, 162.24 42.87, 55.81 -103.48, -8.54 57.38, 81.17 -97.02, -26.48 in-in in 7.522 Saltbr-in 3.1539 HRD-in -69.09, -49.97 76.47, -2.8 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -35.16 APE8-rot-na 328.72 APE67-dihe-in -78.06, -0.48 -64.76, -24.4 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 C584S None None XRAY 2.7 0.215 0.263 C 309.0 265.0 32 30 21 9 [[478, 756]] 1.0 6nvl Homo sapiens TYR_FGFR1_HUMAN TYR 2.1e-104 354.4 1.0 260.0 260.0 640 641 642 644 646 514 531 535 620 622 621 623.0 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6NVLD P11362 471 762 822.0 XL6:804 Type1.5_Back Inactive DFGin 5.1576 13.3104 BLAplus -117.28, 161.88 52.71, 45.04 -93.07, -6.01 60.08, 84.31 -96.46, -42.94 in-none in 7.3629 Saltbr-none 999.0 HRD-in -74.01, -57.04 84.17, -3.83 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -97.3, 154.56 APE9-dihe-in -112.92, 85.91 APE8-dihe-out -57.48, -12.84 APE8-rot-na 334.14 APE67-dihe-in -78.36, -8.15 -65.38, -24.93 APE12-dist-na 16.4701 APE11-dist-na 19.4008 APE10-dist-na 16.585 APE9-dist-out 11.3348 C584S None None XRAY 2.7 0.215 0.263 D 309.0 269.0 23 30 21 9 [[478, 756]] 1.0 6nvl Homo sapiens TYR_FGFR1_HUMAN TYR 2.1e-104 354.4 1.0 260.0 260.0 640 641 642 644 646 514 531 535 620 622 621 623.0 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR4 FGFR4_HUMAN 6NVHA P22455 453 750 802.0 XL6:60803 Type1.5_Back Inactive DFGin 5.2448 13.4006 BLAplus -105.65, 156.33 59.41, 40.23 -87.91, -7.9 56.0, 80.86 -110.13, 11.2 in-in in 7.6449 Saltbr-in 2.9087 HRD-in -72.21, -55.48 85.67, -17.85 in-out-out SNCioo out-out ActLoopNT-out 8.8817 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 119.32 APE8-dihe-in -79.08, 68.56 APE8-rot-na 34.44 APE67-dihe-in -72.6, -11.42 -66.3, -25.11 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 9.0923 None None None XRAY 1.9 0.213 0.234 A 300.0 271.0 18 30 15 15 [[467, 745]] 1.0 6nvh Homo sapiens TYR_FGFR4_HUMAN TYR 8e-101 342.6 1.0 261.0 261.0 629 630 631 633 635 503 520 524 609 611 610 612.0 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4

Ligand: XL6

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name