Ligand: MP7

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 66.7% 3NAXA
DFGout None 1 33.3% 3QC4B
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PDPK1 PDPK1_HUMAN 3NAXA O15530 76 360 556.0 MP7:363 Type2 Inactive DFGout 15.13 9.52 BBAminus -103.03, 154.8 -117.91, 140.31 -115.35, 34.44 271.6, 90.85 93.28, 8.79 out-out out 17.084 Saltbr-out 10.258 HRD-in -72.23, -50.17 78.89, -10.91 out-in-none SNCoin in-none ActLoopNT-in 2.852 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -64.19, -19.08 999.0, -56.98 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 1.75 0.166 0.195 A 311 278 7 0 0 7 [[82, 342]] 1.0 3nax AGC_PDPK1_HUMAN AGC 1.3e-84 289.3 1 260 260 222 223 224 226 228 111 130 134 202 204 203 205 264 252 247 246 245 244 243 242 241 160 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 3QC4A O15530 76 359 556.0 MP7:60001 Type2 Inactive DFGout 15.145 8.418 BBAminus -116.84, 146.54 -96.89, 143.53 -123.04, 29.2 249.8, 111.12 113.47, -5.45 out-out out 19.868 Saltbr-out 17.818 HRD-in -79.45, -51.8 76.86, -8.13 out-in-in SNCoii in-in ActLoopNT-in 3.035 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.28, 161.52 APE9-dihe-na 127.76, -165.1 APE8-dihe-in -132.92, 137.19 APE8-rot-in 293.31 APE67-dihe-in -63.51, -29.78 -55.77, -40.56 APE12-dist-in 7.646 APE11-dist-in 10.891 APE10-dist-in 5.098 APE9-dist-in 3.603 E303A,K304A SEP241 SEP241 XRAY 1.8 0.174 0.213 A 314 277 7 0 0 7 [[82, 342]] 1.0 3qc4 AGC_PDPK1_HUMAN AGC 5.4e-84 287.2 1 260 260 222 223 224 226 228 111 130 134 202 204 203 205 264 252 247 246 245 244 243 242 241 160 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 3QC4B O15530 51 359 556.0 MP7:60002 Type2 Inactive DFGout 15.503 8.299 None -106.7, 145.77 -96.8, 153.42 -131.45, 34.1 235.15, 115.54 107.65, 4.91 out-out out 18.058 Saltbr-out 15.17 HRD-in -74.82, -53.49 77.73, -9.15 out-in-in SNCoii in-in ActLoopNT-in 2.934 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.95, 158.08 APE9-dihe-na 130.3, -155.43 APE8-dihe-in -143.11, 135.86 APE8-rot-in 293.55 APE67-dihe-in -66.08, -20.71 -55.87, -43.65 APE12-dist-in 7.671 APE11-dist-in 10.946 APE10-dist-in 5.068 APE9-dist-in 3.539 E303A,K304A SEP241 SEP241 XRAY 1.8 0.174 0.213 B 314 274 15 0 0 7 [[82, 342]] 1.0 3qc4 AGC_PDPK1_HUMAN AGC 5.4e-84 287.2 1 260 260 222 223 224 226 228 111 130 134 202 204 203 205 264 252 247 246 245 244 243 242 241 160 3-phosphoinositide-dependent protein kinase 1

Ligand: MP7

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 66.7% 3NAXA
DFGout None 1 33.3% 3QC4B
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PDPK1 PDPK1_HUMAN 3NAXA O15530 76 360 556.0 MP7:363 Type2 Inactive DFGout 15.13 9.52 BBAminus -103.03, 154.8 -117.91, 140.31 -115.35, 34.44 271.6, 90.85 93.28, 8.79 out-out out 17.084 Saltbr-out 10.258 HRD-in -72.23, -50.17 78.89, -10.91 out-in-none SNCoin in-none ActLoopNT-in 2.852 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -64.19, -19.08 999.0, -56.98 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 1.75 0.166 0.195 A 311 278 7 0 0 7 [[82, 342]] 1.0 3nax Homo sapiens AGC_PDPK1_HUMAN AGC 1.3e-84 289.3 1 260 260 222 223 224 226 228 111 130 134 202 204 203 205 264 252 247 246 245 244 243 242 241 160 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 3QC4A O15530 76 359 556.0 MP7:60001 Type2 Inactive DFGout 15.145 8.418 BBAminus -116.84, 146.54 -96.89, 143.53 -123.04, 29.2 249.8, 111.12 113.47, -5.45 out-out out 19.868 Saltbr-out 17.818 HRD-in -79.45, -51.8 76.86, -8.13 out-in-in SNCoii in-in ActLoopNT-in 3.035 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.28, 161.52 APE9-dihe-na 127.76, -165.1 APE8-dihe-in -132.92, 137.19 APE8-rot-in 293.31 APE67-dihe-in -63.51, -29.78 -55.77, -40.56 APE12-dist-in 7.646 APE11-dist-in 10.891 APE10-dist-in 5.098 APE9-dist-in 3.603 E303A,K304A SEP241 SEP241 XRAY 1.8 0.174 0.213 A 314 277 7 0 0 7 [[82, 342]] 1.0 3qc4 Homo sapiens AGC_PDPK1_HUMAN AGC 5.4e-84 287.2 1 260 260 222 223 224 226 228 111 130 134 202 204 203 205 264 252 247 246 245 244 243 242 241 160 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 3QC4B O15530 51 359 556.0 MP7:60002 Type2 Inactive DFGout 15.503 8.299 None -106.7, 145.77 -96.8, 153.42 -131.45, 34.1 235.15, 115.54 107.65, 4.91 out-out out 18.058 Saltbr-out 15.17 HRD-in -74.82, -53.49 77.73, -9.15 out-in-in SNCoii in-in ActLoopNT-in 2.934 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.95, 158.08 APE9-dihe-na 130.3, -155.43 APE8-dihe-in -143.11, 135.86 APE8-rot-in 293.55 APE67-dihe-in -66.08, -20.71 -55.87, -43.65 APE12-dist-in 7.671 APE11-dist-in 10.946 APE10-dist-in 5.068 APE9-dist-in 3.539 E303A,K304A SEP241 SEP241 XRAY 1.8 0.174 0.213 B 314 274 15 0 0 7 [[82, 342]] 1.0 3qc4 Homo sapiens AGC_PDPK1_HUMAN AGC 5.4e-84 287.2 1 260 260 222 223 224 226 228 111 130 134 202 204 203 205 264 252 247 246 245 244 243 242 241 160 3-phosphoinositide-dependent protein kinase 1

Ligand: MP7

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name