Ligand: LH0

Total number of chains: 5
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 80.0% 8WSWA
DFGin BLAminus 1 20.0% 8AAUL
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL LIMK1 LIMK1_HUMAN 8AAUL P53667 330 634 647.0 LH0:60702 Type1 Active DFGin 6.786 14.3596 BLAminus -139.69, 179.69 63.59, 84.26 -97.44, 26.6 302.89, 100.12 -69.05, -22.82 in-in in 8.0099 Saltbr-in 2.978 HRD-in -77.51, -55.38 71.25, -0.11 in-in-in SNCiii in-in ActLoopNT-in 2.9518 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -142.5, 160.37 APE9-dihe-na 102.43, 175.55 APE8-dihe-in -76.32, 127.47 APE8-rot-na 188.29 APE67-dihe-in -71.03, -16.49 -57.76, -26.74 APE12-dist-in 9.2056 APE11-dist-in 11.6205 APE10-dist-in 5.8444 APE9-dist-in 3.7263 None None None XRAY 1.74 0.213 0.24 L 310.0 289.0 16 42 26 16 [[339, 606]] 1.0 8aau TKL_LIMK1_HUMAN TKL 4.5e-77 265.1 3.0 266.0 264.0 477 478 479 481 483 368 384 388 457 459 458 460.0 531 519 514 513 512 511 510 509 508 414 LIM domain kinase 1
TKL LIMK2 LIMK2_HUMAN 8WSWA P53671 330 632 638.0 LH0:701 Type1 Inactive DFGin 6.2241 13.083 BLBplus -143.86, 164.67 66.05, 45.45 -99.55, 149.37 45.26, 77.07 128.31, -28.75 out-out out 15.5854 Saltbr-out 13.7004 HRD-in -62.1, -64.33 86.32, -11.58 out-out-out SNCooo out-out ActLoopNT-out 10.3597 ActLoopCT-out nonTYR APEdihe_aaiai APEdist_oioo APE10-dihe-na -144.43, 115.19 APE9-dihe-na 97.95, -174.87 APE8-dihe-in -74.35, 110.98 APE8-rot-na 35.75 APE67-dihe-in -80.15, -5.25 -93.18, 6.59 APE12-dist-out 14.4685 APE11-dist-in 12.7855 APE10-dist-out 13.1393 APE9-dist-out 11.5464 None None None XRAY 2.5 0.212 0.256 A 303.0 281.0 22 48 26 22 [[331, 603]] 1.0 8wsw TKL_LIMK2_HUMAN TKL 6.8e-77 264.5 3.0 266.0 264.0 468 469 470 472 474 360 376 380 448 450 449 451.0 528 516 511 510 509 508 507 506 505 406 LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8WSWB P53671 330 632 638.0 LH0:701 Type1 Inactive DFGin 6.1964 13.02 BLBplus -144.33, 164.55 66.39, 44.42 -99.91, 149.51 45.77, 76.85 127.25, -28.39 out-out out 15.547 Saltbr-out 14.0292 HRD-in -62.31, -64.15 86.83, -11.17 out-out-out SNCooo out-out ActLoopNT-out 10.3392 ActLoopCT-out nonTYR APEdihe_aaiai APEdist_oioo APE10-dihe-na -145.0, 114.92 APE9-dihe-na 99.06, -178.29 APE8-dihe-in -72.51, 110.69 APE8-rot-na 34.98 APE67-dihe-in -80.47, -5.7 -93.47, 6.74 APE12-dist-out 14.4564 APE11-dist-in 12.8153 APE10-dist-out 13.0294 APE9-dist-out 11.3907 None None None XRAY 2.5 0.212 0.256 B 303.0 281.0 22 48 26 22 [[331, 603]] 1.0 8wsw TKL_LIMK2_HUMAN TKL 6.8e-77 264.5 3.0 266.0 264.0 468 469 470 472 474 360 376 380 448 450 449 451.0 528 516 511 510 509 508 507 506 505 406 LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8WSWC P53671 330 632 638.0 LH0:701 Type1 Inactive DFGin 6.2056 13.056 BLBplus -143.75, 164.15 66.94, 45.19 -100.18, 150.72 45.03, 76.69 126.96, -28.24 out-out out 15.5834 Saltbr-out 13.8047 HRD-in -62.29, -64.05 86.34, -11.59 out-out-out SNCooo out-out ActLoopNT-out 10.3219 ActLoopCT-out nonTYR APEdihe_aaiai APEdist_oioo APE10-dihe-na -138.85, 0.68 APE9-dihe-na -100.32, -174.72 APE8-dihe-in -60.21, 114.43 APE8-rot-na 201.59 APE67-dihe-in -78.75, 1.25 -92.38, 7.31 APE12-dist-out 14.3934 APE11-dist-in 12.8535 APE10-dist-out 13.3265 APE9-dist-out 10.5792 None None None XRAY 2.5 0.212 0.256 C 303.0 281.0 22 48 26 22 [[331, 603]] 1.0 8wsw TKL_LIMK2_HUMAN TKL 6.8e-77 264.5 3.0 266.0 264.0 468 469 470 472 474 360 376 380 448 450 449 451.0 528 516 511 510 509 508 507 506 505 406 LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8WSWD P53671 330 632 638.0 LH0:701 Type1 Inactive DFGin 6.1714 12.9862 BLBplus -144.42, 164.29 66.67, 44.97 -99.33, 148.78 44.58, 76.12 128.82, -27.92 out-out out 15.5011 Saltbr-out 13.888 HRD-in -63.12, -64.04 86.22, -11.79 out-out-out SNCooo out-out ActLoopNT-out 10.3397 ActLoopCT-out nonTYR APEdihe_aaiai APEdist_oioo APE10-dihe-na -139.44, -0.07 APE9-dihe-na -100.72, -173.49 APE8-dihe-in -61.82, 114.37 APE8-rot-na 201.16 APE67-dihe-in -77.38, -2.64 -91.99, 7.01 APE12-dist-out 14.4157 APE11-dist-in 12.7959 APE10-dist-out 13.0728 APE9-dist-out 10.3994 None None None XRAY 2.5 0.212 0.256 D 303.0 281.0 22 48 26 22 [[331, 603]] 1.0 8wsw TKL_LIMK2_HUMAN TKL 6.8e-77 264.5 3.0 266.0 264.0 468 469 470 472 474 360 376 380 448 450 449 451.0 528 516 511 510 509 508 507 506 505 406 LIM domain kinase 2

Ligand: LH0

Total number of chains: 5
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 80.0% 8WSWA
DFGin BLAminus 1 20.0% 8AAUL
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL LIMK1 LIMK1_HUMAN 8AAUL P53667 330 634 647.0 LH0:60702 Type1 Active DFGin 6.786 14.3596 BLAminus -139.69, 179.69 63.59, 84.26 -97.44, 26.6 302.89, 100.12 -69.05, -22.82 in-in in 8.0099 Saltbr-in 2.978 HRD-in -77.51, -55.38 71.25, -0.11 in-in-in SNCiii in-in ActLoopNT-in 2.9518 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -142.5, 160.37 APE9-dihe-na 102.43, 175.55 APE8-dihe-in -76.32, 127.47 APE8-rot-na 188.29 APE67-dihe-in -71.03, -16.49 -57.76, -26.74 APE12-dist-in 9.2056 APE11-dist-in 11.6205 APE10-dist-in 5.8444 APE9-dist-in 3.7263 None None None XRAY 1.74 0.213 0.24 L 310.0 289.0 16 42 26 16 [[339, 606]] 1.0 8aau Homo sapiens TKL_LIMK1_HUMAN TKL 4.5e-77 265.1 3.0 266.0 264.0 477 478 479 481 483 368 384 388 457 459 458 460.0 531 519 514 513 512 511 510 509 508 414 LIM domain kinase 1
TKL LIMK2 LIMK2_HUMAN 8WSWA P53671 330 632 638.0 LH0:701 Type1 Inactive DFGin 6.2241 13.083 BLBplus -143.86, 164.67 66.05, 45.45 -99.55, 149.37 45.26, 77.07 128.31, -28.75 out-out out 15.5854 Saltbr-out 13.7004 HRD-in -62.1, -64.33 86.32, -11.58 out-out-out SNCooo out-out ActLoopNT-out 10.3597 ActLoopCT-out nonTYR APEdihe_aaiai APEdist_oioo APE10-dihe-na -144.43, 115.19 APE9-dihe-na 97.95, -174.87 APE8-dihe-in -74.35, 110.98 APE8-rot-na 35.75 APE67-dihe-in -80.15, -5.25 -93.18, 6.59 APE12-dist-out 14.4685 APE11-dist-in 12.7855 APE10-dist-out 13.1393 APE9-dist-out 11.5464 None None None XRAY 2.5 0.212 0.256 A 303.0 281.0 22 48 26 22 [[331, 603]] 1.0 8wsw Homo sapiens TKL_LIMK2_HUMAN TKL 6.8e-77 264.5 3.0 266.0 264.0 468 469 470 472 474 360 376 380 448 450 449 451.0 528 516 511 510 509 508 507 506 505 406 LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8WSWB P53671 330 632 638.0 LH0:701 Type1 Inactive DFGin 6.1964 13.02 BLBplus -144.33, 164.55 66.39, 44.42 -99.91, 149.51 45.77, 76.85 127.25, -28.39 out-out out 15.547 Saltbr-out 14.0292 HRD-in -62.31, -64.15 86.83, -11.17 out-out-out SNCooo out-out ActLoopNT-out 10.3392 ActLoopCT-out nonTYR APEdihe_aaiai APEdist_oioo APE10-dihe-na -145.0, 114.92 APE9-dihe-na 99.06, -178.29 APE8-dihe-in -72.51, 110.69 APE8-rot-na 34.98 APE67-dihe-in -80.47, -5.7 -93.47, 6.74 APE12-dist-out 14.4564 APE11-dist-in 12.8153 APE10-dist-out 13.0294 APE9-dist-out 11.3907 None None None XRAY 2.5 0.212 0.256 B 303.0 281.0 22 48 26 22 [[331, 603]] 1.0 8wsw Homo sapiens TKL_LIMK2_HUMAN TKL 6.8e-77 264.5 3.0 266.0 264.0 468 469 470 472 474 360 376 380 448 450 449 451.0 528 516 511 510 509 508 507 506 505 406 LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8WSWC P53671 330 632 638.0 LH0:701 Type1 Inactive DFGin 6.2056 13.056 BLBplus -143.75, 164.15 66.94, 45.19 -100.18, 150.72 45.03, 76.69 126.96, -28.24 out-out out 15.5834 Saltbr-out 13.8047 HRD-in -62.29, -64.05 86.34, -11.59 out-out-out SNCooo out-out ActLoopNT-out 10.3219 ActLoopCT-out nonTYR APEdihe_aaiai APEdist_oioo APE10-dihe-na -138.85, 0.68 APE9-dihe-na -100.32, -174.72 APE8-dihe-in -60.21, 114.43 APE8-rot-na 201.59 APE67-dihe-in -78.75, 1.25 -92.38, 7.31 APE12-dist-out 14.3934 APE11-dist-in 12.8535 APE10-dist-out 13.3265 APE9-dist-out 10.5792 None None None XRAY 2.5 0.212 0.256 C 303.0 281.0 22 48 26 22 [[331, 603]] 1.0 8wsw Homo sapiens TKL_LIMK2_HUMAN TKL 6.8e-77 264.5 3.0 266.0 264.0 468 469 470 472 474 360 376 380 448 450 449 451.0 528 516 511 510 509 508 507 506 505 406 LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8WSWD P53671 330 632 638.0 LH0:701 Type1 Inactive DFGin 6.1714 12.9862 BLBplus -144.42, 164.29 66.67, 44.97 -99.33, 148.78 44.58, 76.12 128.82, -27.92 out-out out 15.5011 Saltbr-out 13.888 HRD-in -63.12, -64.04 86.22, -11.79 out-out-out SNCooo out-out ActLoopNT-out 10.3397 ActLoopCT-out nonTYR APEdihe_aaiai APEdist_oioo APE10-dihe-na -139.44, -0.07 APE9-dihe-na -100.72, -173.49 APE8-dihe-in -61.82, 114.37 APE8-rot-na 201.16 APE67-dihe-in -77.38, -2.64 -91.99, 7.01 APE12-dist-out 14.4157 APE11-dist-in 12.7959 APE10-dist-out 13.0728 APE9-dist-out 10.3994 None None None XRAY 2.5 0.212 0.256 D 303.0 281.0 22 48 26 22 [[331, 603]] 1.0 8wsw Homo sapiens TKL_LIMK2_HUMAN TKL 6.8e-77 264.5 3.0 266.0 264.0 468 469 470 472 474 360 376 380 448 450 449 451.0 528 516 511 510 509 508 507 506 505 406 LIM domain kinase 2

Ligand: LH0

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name