Ligand: LH0

Total number of chains: 5
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 80.0% 8WSWA
DFGin BLAminus 1 20.0% 8AAUL

Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TKL LIMK1 LIMK1_HUMAN 8AAUL 1.74 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii LH0 Type1 330 - 634 0 None None LIM domain kinase 1
TKL LIMK2 LIMK2_HUMAN 8WSWA 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8WSWB 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8WSWC 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8WSWD 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2

Ligand: LH0

Total number of chains: 5
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 80.0% 8WSWA
DFGin BLAminus 1 20.0% 8AAUL

Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL LIMK1 LIMK1_HUMAN 8AAUL 1.74 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii LH0 Type1 330 - 634 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 8WSWA 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 8WSWB 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 8WSWC 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 8WSWD 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2 Homo sapiens

Ligand: LH0

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism