Ligand: KY9

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 2 66.7% 8A2AA
DFGin BLBplus 1 33.3% 8A2BA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 8A27A 1.07 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nniai APEdist_aaao KY9 Type3 701 - 985 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8A2AA 1.43 Inactive DFGin‑BLAplus out-out out-out TYR APEdihe_nniai APEdist_aaao KY9 Type3 700 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8A2BA 1.69 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao KY9 Type3 702 - 990 0 None L858R,V948R Epidermal growth factor receptor

Ligand: KY9

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 2 66.7% 8A2AA
DFGin BLBplus 1 33.3% 8A2BA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 8A27A 1.07 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nniai APEdist_aaao KY9 Type3 701 - 985 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8A2AA 1.43 Inactive DFGin‑BLAplus out-out out-out TYR APEdihe_nniai APEdist_aaao KY9 Type3 700 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8A2BA 1.69 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao KY9 Type3 702 - 990 0 None L858R,V948R Epidermal growth factor receptor Homo sapiens

Ligand: KY9

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism