Ligand: JBI

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 3TTJA
DFGin BLAminus 1 50.0% 9QXNAAA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC MAPK10 MK10_HUMAN 3TTJA 2.1 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno JBI Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
TYR EGFR EGFR_HUMAN 9QXNAAA 2.142 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai A1JBI Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor

Ligand: JBI

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 3TTJA
DFGin BLAminus 1 50.0% 9QXNAAA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK10 MK10_HUMAN 3TTJA 2.1 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno JBI Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
TYR EGFR EGFR_HUMAN 9QXNAAA 2.142 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai A1JBI Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens

Ligand: JBI

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism