Ligand: IHP

Total number of chains: 8
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 8 100.0% 5CVHA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CSNK2A1 CSK21_HUMAN 5CVHA 1.848 Active DFGin‑BLAminus in-in in-in ADP, IHP ATPlike, Allosteric 2 - 328 0 None R21S Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 5CVHB 1.848 Active DFGin‑BLAminus in-in in-in ADP, IHP ATPlike, Allosteric 4 - 327 0 None R21S Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 5MPJA 2.14 Active DFGin‑BLAminus in-in in-in ADP, IHP, J2P ATPlike, Allosteric, Allosteric 3 - 328 0 None R21S Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 5OQUA 2.324 Active DFGin‑BLAminus in-in in-in ADP, A4B, IHP ATPlike, Allosteric, Allosteric 4 - 327 0 None R21S Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 5MOEB 1.89 Active DFGin‑BLAminus in-in in-in ADP, IHP, OQC, OQC ATPlike, Allosteric, Allosteric, Allosteric 4 - 326 0 None R21S Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 5ORJA 1.99 Active DFGin‑BLAminus in-in in-in ADP, A4Q, A4Q, IHP ATPlike, Allosteric, Allosteric, Allosteric 3 - 327 0 None R21S Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 5MOEA 1.89 Active DFGin‑BLAminus in-in in-in ADP, IHP, OQC, OQC, OQC ATPlike, Allosteric, Allosteric, Allosteric, Allosteric 3 - 327 0 None R21S Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 3W8LB 2.4 Active DFGin‑BLAminus in-in in-in IHP, IHP Allosteric, Allosteric 4 - 329 0 None I57V Casein kinase II subunit alpha

Ligand: IHP

Total number of chains: 11
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 11 100.0% 9TFXAAAA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CKA1 CSK21_ARATH 9TFYA 5.5 Inactive DFGin‑BLAminus in-in in-out IHP Allosteric 78 - 409 0 None None Casein kinase II subunit alpha-1 Arabidopsis thaliana
CMGC CKA1 CSK21_ARATH 9TFYB 5.5 Inactive DFGin‑BLAminus in-in in-out IHP Allosteric 78 - 409 0 None None Casein kinase II subunit alpha-1 Arabidopsis thaliana
CMGC CKA1 CSK21_ARATH 9TFXAAAA 1.7 Active DFGin‑BLAminus in-in in-in IHP, BEZ Allosteric, Type1 78 - 409 0 None None Casein kinase II subunit alpha-1 Arabidopsis thaliana
CMGC CSNK2A1 CSK21_HUMAN 5CVHA 1.848 Active DFGin‑BLAminus in-in in-in ADP, IHP ATPlike, Allosteric 2 - 328 0 None R21S Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 5CVHB 1.848 Active DFGin‑BLAminus in-in in-in ADP, IHP ATPlike, Allosteric 4 - 327 0 None R21S Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 5MPJA 2.14 Active DFGin‑BLAminus in-in in-in ADP, IHP, J2P ATPlike, Allosteric, Allosteric 3 - 328 0 None R21S Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 5OQUA 2.324 Active DFGin‑BLAminus in-in in-in ADP, A4B, IHP ATPlike, Allosteric, Allosteric 4 - 327 0 None R21S Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 5MOEB 1.89 Active DFGin‑BLAminus in-in in-in ADP, IHP, OQC, OQC ATPlike, Allosteric, Allosteric, Allosteric 4 - 326 0 None R21S Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 5ORJA 1.99 Active DFGin‑BLAminus in-in in-in ADP, A4Q, A4Q, IHP ATPlike, Allosteric, Allosteric, Allosteric 3 - 327 0 None R21S Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 5MOEA 1.89 Active DFGin‑BLAminus in-in in-in ADP, IHP, OQC, OQC, OQC ATPlike, Allosteric, Allosteric, Allosteric, Allosteric 3 - 327 0 None R21S Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 3W8LB 2.4 Active DFGin‑BLAminus in-in in-in IHP, IHP Allosteric, Allosteric 4 - 329 0 None I57V Casein kinase II subunit alpha Homo sapiens

Ligand: IHP

Total number of chains: 3
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 9TFXAAAA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CKA1 CSK21_ARATH 9TFYA 5.5 Inactive DFGin‑BLAminus in-in in-out IHP Allosteric 78 - 409 0 None None Casein kinase II subunit alpha-1 Arabidopsis thaliana
CMGC CKA1 CSK21_ARATH 9TFYB 5.5 Inactive DFGin‑BLAminus in-in in-out IHP Allosteric 78 - 409 0 None None Casein kinase II subunit alpha-1 Arabidopsis thaliana
CMGC CKA1 CSK21_ARATH 9TFXAAAA 1.7 Active DFGin‑BLAminus in-in in-in IHP, BEZ Allosteric, Type1 78 - 409 0 None None Casein kinase II subunit alpha-1 Arabidopsis thaliana