Ligand: AWJ

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 50.0% 4CD0A
DFGin None 2 50.0% 7Z5XA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR ALK ALK_HUMAN 4CD0A 2.23 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai AWJ Type1 1094 - 1402 0 None L1196M ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 7R7RA 1.935 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaai AWJ Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor
TYR ROS1 ROS1_HUMAN 7Z5XA 2.035 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao AWJ Type1 1937 - 2225 0 None None Proto-oncogene tyrosine-protein kinase ROS
TYR ROS1 ROS1_HUMAN 7Z5XB 2.035 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao AWJ Type1 1937 - 2226 0 None None Proto-oncogene tyrosine-protein kinase ROS

Ligand: AWJ

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 50.0% 4CD0A
DFGin None 2 50.0% 7Z5XA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR ALK ALK_HUMAN 4CD0A 2.23 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai AWJ Type1 1094 - 1402 0 None L1196M ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 7R7RA 1.935 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaai AWJ Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ROS1 ROS1_HUMAN 7Z5XA 2.035 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao AWJ Type1 1937 - 2225 0 None None Proto-oncogene tyrosine-protein kinase ROS Homo sapiens
TYR ROS1 ROS1_HUMAN 7Z5XB 2.035 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao AWJ Type1 1937 - 2226 0 None None Proto-oncogene tyrosine-protein kinase ROS Homo sapiens

Ligand: AWJ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism