Ligand: 87B

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein

Ligand: 87B

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 2 66.7% 7Z9TAAA
DFGin BLBplus 1 33.3% 7Z6IAAA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK14 MK14_MOUSE 7Z9TAAA 2.6 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaoio APEdist_iioo 87B Type1 5 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 7Z9TBBB 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo 87B, ATP Type3, Allosteric 4 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 7Z6IAAA 2.25 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oioo IIM, 87B Type1, Type1 5 - 354 0 None C162S Mitogen-activated protein kinase 14 Mus musculus

Ligand: 87B

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 2 66.7% 7Z9TAAA
DFGin BLBplus 1 33.3% 7Z6IAAA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK14 MK14_MOUSE 7Z9TAAA 2.6 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaoio APEdist_iioo 87B Type1 5 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 7Z9TBBB 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo 87B, ATP Type3, Allosteric 4 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 7Z6IAAA 2.25 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oioo IIM, 87B Type1, Type1 5 - 354 0 None C162S Mitogen-activated protein kinase 14 Mus musculus