Ligand: 33A

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 2OK1A
DFGin BLAminus 1 50.0% 2OJIA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_HUMAN 2OJIA P28482 15 358 360.0 33A:60360 Type1 Inactive DFGin 6.7854 16.3983 BLAminus -132.53, 175.62 62.73, 87.52 -104.73, 37.95 284.25, 59.44 -73.68, -20.82 out-in out 10.1012 Saltbr-in 3.1148 HRD-in -72.86, -54.76 76.49, 2.85 in-in-out SNCiio in-out ActLoopNT-in 2.8555 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -103.26, -26.54 APE9-dihe-na -67.43, 166.5 APE8-dihe-in -61.43, 135.98 APE8-rot-in 299.82 APE67-dihe-in -66.79, -11.81 -72.57, -38.73 APE12-dist-out 14.6525 APE11-dist-in 11.2062 APE10-dist-in 7.3794 APE9-dist-in 4.3911 None None None XRAY 2.6 0.239 0.267 A 380.0 344.0 0 31 31 0 [[25, 313]] 1.0 2oji CMGC_MAPK1_HUMAN CMGC 1.1e-85 293.5 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
CMGC MAPK10 MK10_HUMAN 2OK1A P53779 46 400 464.0 33A:1 Type1 Inactive DFGin 3.5668 14.6729 ABAminus -92.46, -22.86 -139.75, 178.47 -118.63, 10.81 302.45, 82.92 65.72, -145.61 out-out out 10.0347 Saltbr-out 5.5345 HRD-in -66.04, -65.13 76.53, -1.29 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 127.98 APE8-dihe-in -86.1, 116.64 APE8-rot-in 298.81 APE67-dihe-in -61.55, -38.95 -106.56, 7.49 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.9345 None None None XRAY 2.4 0.246 0.294 A 365.0 333.0 15 27 14 13 [[64, 359]] 1.0 2ok1 CMGC_MAPK10_HUMAN CMGC 1.4e-85 293.1 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10

Ligand: 33A

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 2OK1A
DFGin BLAminus 1 50.0% 2OJIA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_HUMAN 2OJIA P28482 15 358 360.0 33A:60360 Type1 Inactive DFGin 6.7854 16.3983 BLAminus -132.53, 175.62 62.73, 87.52 -104.73, 37.95 284.25, 59.44 -73.68, -20.82 out-in out 10.1012 Saltbr-in 3.1148 HRD-in -72.86, -54.76 76.49, 2.85 in-in-out SNCiio in-out ActLoopNT-in 2.8555 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -103.26, -26.54 APE9-dihe-na -67.43, 166.5 APE8-dihe-in -61.43, 135.98 APE8-rot-in 299.82 APE67-dihe-in -66.79, -11.81 -72.57, -38.73 APE12-dist-out 14.6525 APE11-dist-in 11.2062 APE10-dist-in 7.3794 APE9-dist-in 4.3911 None None None XRAY 2.6 0.239 0.267 A 380.0 344.0 0 31 31 0 [[25, 313]] 1.0 2oji Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.1e-85 293.5 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
CMGC MAPK10 MK10_HUMAN 2OK1A P53779 46 400 464.0 33A:1 Type1 Inactive DFGin 3.5668 14.6729 ABAminus -92.46, -22.86 -139.75, 178.47 -118.63, 10.81 302.45, 82.92 65.72, -145.61 out-out out 10.0347 Saltbr-out 5.5345 HRD-in -66.04, -65.13 76.53, -1.29 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 127.98 APE8-dihe-in -86.1, 116.64 APE8-rot-in 298.81 APE67-dihe-in -61.55, -38.95 -106.56, 7.49 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.9345 None None None XRAY 2.4 0.246 0.294 A 365.0 333.0 15 27 14 13 [[64, 359]] 1.0 2ok1 Homo sapiens CMGC_MAPK10_HUMAN CMGC 1.4e-85 293.1 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10

Ligand: 33A

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name