Ligand: 2I5

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 1 100.0% 7OVKA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
STE MAP2K7 MP2K7_HUMAN 7OVKA 2.05 Inactive DFGin‑None in-na none-none nonTYR APEdihe_aannn APEdist_nnnn 2I5 Type1.5_Back 102 - 401 0 None None Dual specificity mitogen-activated protein kinase kinase 7

Ligand: 2I5

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 1 100.0% 7OVKA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
STE MAP2K7 MP2K7_HUMAN 7OVKA 2.05 Inactive DFGin‑None in-na none-none nonTYR APEdihe_aannn APEdist_nnnn 2I5 Type1.5_Back 102 - 401 0 None None Dual specificity mitogen-activated protein kinase kinase 7 Homo sapiens

Ligand: 2I5

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism