Ligand: 1QK (Dinaciclib)

Total number of chains: 6
Active chains: 3
Total number of genes: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 50.0% 5L2WA
DFGin BLBminus 1 16.7% 8FOWA
DFGin BLBplus 1 16.7% 6GU6A
None None 1 16.7% 4KD1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CDK1 CDK1_HUMAN 6GU6A 2.33 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo 1QK Type1 1 - 291 0 None None Cyclin-dependent kinase 1
CMGC CDK2 CDK2_HUMAN 5L2WA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1QK Type1 1 - 297 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 8FOWA 1.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nooo 1QK, 7TW Type1, Type3 3 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4KD1A 1.7 Inactive None‑None out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 1QK Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK3 CDK3_HUMAN 8H4RA 2.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1QK Type1 2 - 288 0 TPO160 None Cyclin-dependent kinase 3
CMGC CDK7 CDK7_HUMAN 8P78J 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1QK Type1 10 - 310 0 None None Cyclin-dependent kinase 7

Ligand: 1QK (Dinaciclib)

Total number of chains: 6
Active chains: 3
Total number of genes: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 50.0% 5L2WA
DFGin BLBminus 1 16.7% 8FOWA
DFGin BLBplus 1 16.7% 6GU6A
None None 1 16.7% 4KD1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CDK1 CDK1_HUMAN 6GU6A 2.33 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo 1QK Type1 1 - 291 0 None None Cyclin-dependent kinase 1 Homo sapiens
CMGC CDK2 CDK2_HUMAN 5L2WA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1QK Type1 1 - 297 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 8FOWA 1.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nooo 1QK, 7TW Type1, Type3 3 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4KD1A 1.7 Inactive None‑None out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 1QK Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK3 CDK3_HUMAN 8H4RA 2.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1QK Type1 2 - 288 0 TPO160 None Cyclin-dependent kinase 3 Homo sapiens
CMGC CDK7 CDK7_HUMAN 8P78J 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1QK Type1 10 - 310 0 None None Cyclin-dependent kinase 7 Homo sapiens

Ligand: 1QK (Dinaciclib)

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism