CMGC_CDK3 (Cyclin-dependent kinase 3)

Total number of chains: 4
Active chains: 4
Uniprot: CDK3_HUMAN
Kinase Domain Residues: 4 - 286
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% AF-Q00526-K1A

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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q00526-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 294 0 None None Cyclin-dependent kinase 3
AF-Q00526-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 294 0 None None Cyclin-dependent kinase 3
7XQKA 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 3 - 288 0 TPO160 None Cyclin-dependent kinase 3
8H4RA 2.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1QK Type1 2 - 288 0 TPO160 None Cyclin-dependent kinase 3

CMGC_CDK3 (Cyclin-dependent kinase 3)

Total number of chains: 4
Active chains: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% AF-Q00526-K1A

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CDK3_HUMAN AF-Q00526-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 294 0 None None Cyclin-dependent kinase 3 Homo sapiens
CDK3_HUMAN AF-Q00526-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 294 0 None None Cyclin-dependent kinase 3 Homo sapiens
CDK3_HUMAN 7XQKA 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 3 - 288 0 TPO160 None Cyclin-dependent kinase 3 Homo sapiens
CDK3_HUMAN 8H4RA 2.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1QK Type1 2 - 288 0 TPO160 None Cyclin-dependent kinase 3 Homo sapiens

CMGC_CDK3 (Cyclin-dependent kinase 3)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism