Ligand: 1HX

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 3 100.0% 4ITJB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TKL RIPK1 RIPK1_HUMAN 4ITJA 1.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 1HX Type2 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITJB 1.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn 1HX Type2 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9HY8B 2.98 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 1HX Type3 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1

Ligand: 1HX

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 3 100.0% 4ITJB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL RIPK1 RIPK1_HUMAN 4ITJA 1.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 1HX Type2 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 4ITJB 1.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn 1HX Type2 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9HY8B 2.98 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 1HX Type3 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens

Ligand: 1HX

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism