Ligand: 1HX

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 3 100.0% 4ITJB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL RIPK1 RIPK1_HUMAN 4ITJA Q13546 8 294 671.0 1HX:301 Type2 Inactive DFGout 14.0125 9.1293 BBAminus -136.14, 158.72 -113.11, 65.66 -67.83, -29.38 295.84, 1.08 -82.31, 2.17 out-out out 13.7931 Saltbr-out 12.1104 HRD-in -65.33, -53.51 83.49, -21.7 out-out-out SNCooo out-out ActLoopNT-out 6.4701 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 67.46 APE8-dihe-in -61.72, 146.74 APE8-rot-out 197.87 APE67-dihe-in -67.31, -25.57 -109.11, 4.06 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.622 C34A,C127A,C233A,C240A None None XRAY 1.8 0.189 0.222 A 294.0 261.0 26 41 23 18 [[17, 287]] 1.0 4itj TKL_RIPK1_HUMAN TKL 1.2e-72 250.6 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITJB Q13546 7 294 671.0 1HX:301 Type2 Inactive DFGout 14.0864 9.4307 BBAminus -128.78, 163.03 -112.89, 67.55 -67.91, -19.67 298.87, 2.73 -88.99, 2.64 out-out out 13.5773 Saltbr-out 12.0822 HRD-in -67.42, -52.94 85.17, -18.35 out-out-none SNCoon out-none ActLoopNT-out 6.3878 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -9.31 APE8-rot-in 268.88 APE67-dihe-in -69.48, -22.39 -56.33, -37.34 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C34A,C127A,C233A,C240A None None XRAY 1.8 0.189 0.222 B 294.0 276.0 12 41 29 12 [[17, 287]] 1.0 4itj TKL_RIPK1_HUMAN TKL 1.2e-72 250.6 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9HY8B Q13546 7 294 671.0 1HX:305 Type3 Inactive DFGout 13.9044 9.0782 BBAminus -137.15, 163.21 -126.56, 62.14 -66.56, -24.08 304.02, 3.22 -81.88, 1.19 out-out out 13.7445 Saltbr-out 12.3214 HRD-out -85.29, 111.77 -72.25, -38.63 out-out-out SNCooo out-out ActLoopNT-out 6.1145 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -35.46 APE8-rot-out 195.34 APE67-dihe-in -63.95, -33.12 -61.2, -31.9 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.98 0.23 0.295 B 297.0 271.0 17 41 29 12 [[17, 287]] 1.0 9hy8 TKL_RIPK1_HUMAN TKL 1.3e-72 250.5 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1

Ligand: 1HX

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 3 100.0% 4ITJB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL RIPK1 RIPK1_HUMAN 4ITJA Q13546 8 294 671.0 1HX:301 Type2 Inactive DFGout 14.0125 9.1293 BBAminus -136.14, 158.72 -113.11, 65.66 -67.83, -29.38 295.84, 1.08 -82.31, 2.17 out-out out 13.7931 Saltbr-out 12.1104 HRD-in -65.33, -53.51 83.49, -21.7 out-out-out SNCooo out-out ActLoopNT-out 6.4701 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 67.46 APE8-dihe-in -61.72, 146.74 APE8-rot-out 197.87 APE67-dihe-in -67.31, -25.57 -109.11, 4.06 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.622 C34A,C127A,C233A,C240A None None XRAY 1.8 0.189 0.222 A 294.0 261.0 26 41 23 18 [[17, 287]] 1.0 4itj Homo sapiens TKL_RIPK1_HUMAN TKL 1.2e-72 250.6 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITJB Q13546 7 294 671.0 1HX:301 Type2 Inactive DFGout 14.0864 9.4307 BBAminus -128.78, 163.03 -112.89, 67.55 -67.91, -19.67 298.87, 2.73 -88.99, 2.64 out-out out 13.5773 Saltbr-out 12.0822 HRD-in -67.42, -52.94 85.17, -18.35 out-out-none SNCoon out-none ActLoopNT-out 6.3878 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -9.31 APE8-rot-in 268.88 APE67-dihe-in -69.48, -22.39 -56.33, -37.34 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C34A,C127A,C233A,C240A None None XRAY 1.8 0.189 0.222 B 294.0 276.0 12 41 29 12 [[17, 287]] 1.0 4itj Homo sapiens TKL_RIPK1_HUMAN TKL 1.2e-72 250.6 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9HY8B Q13546 7 294 671.0 1HX:305 Type3 Inactive DFGout 13.9044 9.0782 BBAminus -137.15, 163.21 -126.56, 62.14 -66.56, -24.08 304.02, 3.22 -81.88, 1.19 out-out out 13.7445 Saltbr-out 12.3214 HRD-out -85.29, 111.77 -72.25, -38.63 out-out-out SNCooo out-out ActLoopNT-out 6.1145 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -35.46 APE8-rot-out 195.34 APE67-dihe-in -63.95, -33.12 -61.2, -31.9 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.98 0.23 0.295 B 297.0 271.0 17 41 29 12 [[17, 287]] 1.0 9hy8 Homo sapiens TKL_RIPK1_HUMAN TKL 1.3e-72 250.5 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1

Ligand: 1HX

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name