TYR_TYK2-1 (Non-receptor tyrosine-protein kinase TYK2)

Total number of chains: 42
Uniprot: TYK2_HUMAN
Kinase Domain Residues: 589 - 868
Spatial label Dihedral label Number of Chains Representative
DFGin None 42 8S9AA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
7AX4A 2.12 Pseudo DFGin‑None in-na out-out NM7 Type1 579 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
7AX4B 2.12 Pseudo DFGin‑None in-na out-out NM7 Type1 579 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
8S98A 1.87 Pseudo DFGin‑None in-na out-out ZRU Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
8S98B 1.87 Pseudo DFGin‑None in-na out-out ZRU Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
8S98C 1.87 Pseudo DFGin‑None in-na out-out ZRU Type1 578 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
8S99A 1.71 Pseudo DFGin‑None in-na out-out ZS3 Type1 578 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
8S99B 1.71 Pseudo DFGin‑None in-na out-out ZS3 Type1 579 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
8S99C 1.71 Pseudo DFGin‑None in-na out-out ZS3 Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
8S9AA 1.83 Pseudo DFGin‑None in-na out-out ZSB Type1 577 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
8S9AB 1.83 Pseudo DFGin‑None in-na out-out ZSB Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
8S9AC 1.83 Pseudo DFGin‑None in-na out-out ZSB Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
5TKDA 1.92 Pseudo DFGin‑None in-na out-out 7GL Type1 581 - 866 0 None None Non-receptor tyrosine-protein kinase TYK2
5TKDB 1.92 Pseudo DFGin‑None in-na out-out 7GL Type1 581 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
3ZONA 2.15 Pseudo DFGin‑None in-na out-out IK1 Type1 577 - 870 0 None None Non-receptor tyrosine-protein kinase TYK2
6NZRA 2.56 Pseudo DFGin‑None in-na out-out LAJ Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
6NZRB 2.56 Pseudo DFGin‑None in-na out-out LAJ Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
4WOVA 1.8 Pseudo DFGin‑None in-na out-out 3SM Type1 580 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2
4WOVB 1.8 Pseudo DFGin‑None in-na out-out 3SM Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
6NSLA 2.15 Pseudo DFGin‑None in-na out-out KZJ Type1 581 - 866 0 None None Non-receptor tyrosine-protein kinase TYK2
6NSLB 2.15 Pseudo DFGin‑None in-na out-out KZJ Type1 581 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
6NZEA 1.96 Pseudo DFGin‑None in-na out-out L8Y Type1 581 - 863 0 None None Non-receptor tyrosine-protein kinase TYK2
6NZEB 1.96 Pseudo DFGin‑None in-na out-out L8Y Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
6NZFA 2.39 Pseudo DFGin‑None in-na out-out L91 Type1 580 - 865 0 None None Non-receptor tyrosine-protein kinase TYK2
6NZFB 2.39 Pseudo DFGin‑None in-na out-out L91 Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
6NZHA 2.73 Pseudo DFGin‑None in-na out-out L9A Type1 581 - 866 0 None None Non-receptor tyrosine-protein kinase TYK2
6NZHB 2.73 Pseudo DFGin‑None in-na out-out L9A Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
6NZPA 2.35 Pseudo DFGin‑None in-na out-out LB7 Type1 580 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2
6NZPB 2.35 Pseudo DFGin‑None in-na out-out LB7 Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
6NZQA 2.11 Pseudo DFGin‑None in-na out-out LB4 Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
6NZQB 2.11 Pseudo DFGin‑None in-na out-out LB4 Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
7K7OA 2.82 Pseudo DFGin‑None in-na out-out VZJ Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
7K7OB 2.82 Pseudo DFGin‑None in-na out-out VZJ Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
7K7QA 2.27 Pseudo DFGin‑None in-na out-out VZG Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
7K7QB 2.27 Pseudo DFGin‑None in-na out-out VZG Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
8TB5A 2.32 Pseudo DFGin‑None in-na out-out ZOQ Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
8TB5B 2.32 Pseudo DFGin‑None in-na out-out ZOQ Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
8TB6A 1.96 Pseudo DFGin‑None in-na out-out ZOI Type1 572 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2
8TB6B 1.96 Pseudo DFGin‑None in-na out-out ZOI Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
5C01A 2.15 Pseudo DFGin‑None in-na out-out UNL Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
5C01B 2.15 Pseudo DFGin‑None in-na out-out UNL Type1 579 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2
5C03A 1.9 Pseudo DFGin‑None in-na out-out AGS Type1 579 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2
5C03B 1.9 Pseudo DFGin‑None in-na out-out AGS Type1 580 - 870 0 None None Non-receptor tyrosine-protein kinase TYK2

TYR_TYK2-1 (Non-receptor tyrosine-protein kinase TYK2)

Total number of chains: 42
Spatial label Dihedral label Number of Chains Representative
DFGin None 42 8S9AA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYK2_HUMAN 7AX4A 2.12 Pseudo DFGin‑None in-na out-out NM7 Type1 579 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 7AX4B 2.12 Pseudo DFGin‑None in-na out-out NM7 Type1 579 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 8S98A 1.87 Pseudo DFGin‑None in-na out-out ZRU Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 8S98B 1.87 Pseudo DFGin‑None in-na out-out ZRU Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 8S98C 1.87 Pseudo DFGin‑None in-na out-out ZRU Type1 578 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 8S99A 1.71 Pseudo DFGin‑None in-na out-out ZS3 Type1 578 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 8S99B 1.71 Pseudo DFGin‑None in-na out-out ZS3 Type1 579 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 8S99C 1.71 Pseudo DFGin‑None in-na out-out ZS3 Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 8S9AA 1.83 Pseudo DFGin‑None in-na out-out ZSB Type1 577 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 8S9AB 1.83 Pseudo DFGin‑None in-na out-out ZSB Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 8S9AC 1.83 Pseudo DFGin‑None in-na out-out ZSB Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 5TKDA 1.92 Pseudo DFGin‑None in-na out-out 7GL Type1 581 - 866 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 5TKDB 1.92 Pseudo DFGin‑None in-na out-out 7GL Type1 581 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 3ZONA 2.15 Pseudo DFGin‑None in-na out-out IK1 Type1 577 - 870 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 6NZRA 2.56 Pseudo DFGin‑None in-na out-out LAJ Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 6NZRB 2.56 Pseudo DFGin‑None in-na out-out LAJ Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 4WOVA 1.8 Pseudo DFGin‑None in-na out-out 3SM Type1 580 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 4WOVB 1.8 Pseudo DFGin‑None in-na out-out 3SM Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 6NSLA 2.15 Pseudo DFGin‑None in-na out-out KZJ Type1 581 - 866 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 6NSLB 2.15 Pseudo DFGin‑None in-na out-out KZJ Type1 581 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 6NZEA 1.96 Pseudo DFGin‑None in-na out-out L8Y Type1 581 - 863 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 6NZEB 1.96 Pseudo DFGin‑None in-na out-out L8Y Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 6NZFA 2.39 Pseudo DFGin‑None in-na out-out L91 Type1 580 - 865 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 6NZFB 2.39 Pseudo DFGin‑None in-na out-out L91 Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 6NZHA 2.73 Pseudo DFGin‑None in-na out-out L9A Type1 581 - 866 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 6NZHB 2.73 Pseudo DFGin‑None in-na out-out L9A Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 6NZPA 2.35 Pseudo DFGin‑None in-na out-out LB7 Type1 580 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 6NZPB 2.35 Pseudo DFGin‑None in-na out-out LB7 Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 6NZQA 2.11 Pseudo DFGin‑None in-na out-out LB4 Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 6NZQB 2.11 Pseudo DFGin‑None in-na out-out LB4 Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 7K7OA 2.82 Pseudo DFGin‑None in-na out-out VZJ Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 7K7OB 2.82 Pseudo DFGin‑None in-na out-out VZJ Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 7K7QA 2.27 Pseudo DFGin‑None in-na out-out VZG Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 7K7QB 2.27 Pseudo DFGin‑None in-na out-out VZG Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 8TB5A 2.32 Pseudo DFGin‑None in-na out-out ZOQ Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 8TB5B 2.32 Pseudo DFGin‑None in-na out-out ZOQ Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 8TB6A 1.96 Pseudo DFGin‑None in-na out-out ZOI Type1 572 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 8TB6B 1.96 Pseudo DFGin‑None in-na out-out ZOI Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 5C01A 2.15 Pseudo DFGin‑None in-na out-out UNL Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 5C01B 2.15 Pseudo DFGin‑None in-na out-out UNL Type1 579 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 5C03A 1.9 Pseudo DFGin‑None in-na out-out AGS Type1 579 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYK2_HUMAN 5C03B 1.9 Pseudo DFGin‑None in-na out-out AGS Type1 580 - 870 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens

TYR_TYK2-1 (Non-receptor tyrosine-protein kinase TYK2)

Total number of chains: 0
Spatial label Dihedral label Number of Chains Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism