TKL_TNNI3K (Serine/threonine-protein kinase TNNI3K)

Total number of chains: 22
Active chains: 1
Uniprot: TNI3K_HUMAN
Kinase Domain Residues: 463 - 721
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 14 63.6% AF-Q59H18-K3A
DFGout BBAminus 8 36.4% 7MGJA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q59H18-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 455 - 729 0 None None Serine/threonine-protein kinase TNNI3K
AF-Q59H18-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi No_ligand No_ligand 455 - 729 0 None None Serine/threonine-protein kinase TNNI3K
4YFFC 3.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nooo 4CV Type1 452 - 725 0 None None Serine/threonine-protein kinase TNNI3K
4YFFD 3.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nnno 4CV Type1 452 - 726 0 None None Serine/threonine-protein kinase TNNI3K
6B5JA 2.97 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_nnno CV4 Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
6B5JC 2.97 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nooo CV4 Type1 451 - 726 0 None None Serine/threonine-protein kinase TNNI3K
6B5JD 2.97 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nnno CV4 Type1 452 - 726 0 None None Serine/threonine-protein kinase TNNI3K
4YFIA 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_nnno 4CW Type1 441 - 726 0 None None Serine/threonine-protein kinase TNNI3K
4YFIB 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nnno 4CW Type1 451 - 729 0 None None Serine/threonine-protein kinase TNNI3K
4YFIC 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_nnno 4CW Type1 441 - 726 0 None None Serine/threonine-protein kinase TNNI3K
4YFID 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nnno 4CW Type1 451 - 729 0 None None Serine/threonine-protein kinase TNNI3K
7MGKA 3.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnno ZGD Type2 444 - 726 0 None None Serine/threonine-protein kinase TNNI3K
7MGKB 3.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnno ZGD Type2 444 - 727 0 None None Serine/threonine-protein kinase TNNI3K
7MGKC 3.1 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanai APEdist_nnnn ZGD Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
7MGKD 3.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnoo ZGD Type2 444 - 727 0 None None Serine/threonine-protein kinase TNNI3K
7MGJA 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnno ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
7MGJB 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnoo ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
7MGJC 2.95 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanai APEdist_nnnn ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
7MGJD 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnoo ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
4YFFA 3.07 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanai APEdist_nnnn 4CV Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
4YFFB 3.07 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn 4CV Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
6B5JB 2.97 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanai APEdist_nnnn CV4 Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K

TKL_TNNI3K (Serine/threonine-protein kinase TNNI3K)

Total number of chains: 22
Active chains: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 14 63.6% AF-Q59H18-K3A
DFGout BBAminus 8 36.4% 7MGJA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TNI3K_HUMAN AF-Q59H18-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 455 - 729 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TNI3K_HUMAN AF-Q59H18-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi No_ligand No_ligand 455 - 729 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TNI3K_HUMAN 4YFFC 3.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nooo 4CV Type1 452 - 725 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TNI3K_HUMAN 4YFFD 3.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nnno 4CV Type1 452 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TNI3K_HUMAN 6B5JA 2.97 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_nnno CV4 Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TNI3K_HUMAN 6B5JC 2.97 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nooo CV4 Type1 451 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TNI3K_HUMAN 6B5JD 2.97 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nnno CV4 Type1 452 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TNI3K_HUMAN 4YFIA 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_nnno 4CW Type1 441 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TNI3K_HUMAN 4YFIB 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nnno 4CW Type1 451 - 729 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TNI3K_HUMAN 4YFIC 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_nnno 4CW Type1 441 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TNI3K_HUMAN 4YFID 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nnno 4CW Type1 451 - 729 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TNI3K_HUMAN 7MGKA 3.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnno ZGD Type2 444 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TNI3K_HUMAN 7MGKB 3.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnno ZGD Type2 444 - 727 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TNI3K_HUMAN 7MGKC 3.1 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanai APEdist_nnnn ZGD Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TNI3K_HUMAN 7MGKD 3.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnoo ZGD Type2 444 - 727 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TNI3K_HUMAN 7MGJA 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnno ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TNI3K_HUMAN 7MGJB 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnoo ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TNI3K_HUMAN 7MGJC 2.95 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanai APEdist_nnnn ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TNI3K_HUMAN 7MGJD 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnoo ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TNI3K_HUMAN 4YFFA 3.07 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanai APEdist_nnnn 4CV Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TNI3K_HUMAN 4YFFB 3.07 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn 4CV Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TNI3K_HUMAN 6B5JB 2.97 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanai APEdist_nnnn CV4 Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens

TKL_TNNI3K (Serine/threonine-protein kinase TNNI3K)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism