TKL_RIPK3 (Receptor-interacting serine/threonine-protein kinase 3)

Total number of chains: 9
Active chains: 2
Uniprot: RIPK3_HUMAN
Kinase Domain Residues: 21 - 285
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 66.7% AF-Q9Y572-K1A
DFGin BLBplus 3 33.3% 9LFUB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
RIPK3 AF-Q9Y572-K1A Q9Y572 13 293 518.0 No_ligand No_ligand Active DFGin 6.1841 14.1071 BLAminus -136.64, 175.02 56.98, 73.57 -88.11, 18.5 298.3, 99.24 -61.96, -29.73 in-in in 8.2485 Saltbr-in 2.6925 HRD-in -72.03, -44.39 65.31, -2.99 in-in-in SNCiii in-in ActLoopNT-in 3.0657 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -86.86, 138.33 APE9-dihe-na 114.87, 169.56 APE8-dihe-in -80.98, 116.64 APE8-rot-in 302.32 APE67-dihe-in -59.85, -33.44 -51.1, -38.34 APE12-dist-in 12.498 APE11-dist-in 11.5437 APE10-dist-in 6.9311 APE9-dist-in 3.6454 None None None AF2 -1.0 1.0 1.0 A 281.0 281.0 0 30 30 0 [[21, 285]] 1.0 AF-Q9Y572-K1 TKL_RIPK3_HUMAN TKL 7.5e-66 228.3 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 AF-Q9Y572-K3A Q9Y572 13 293 518.0 No_ligand No_ligand Active DFGin 6.145 14.1327 BLAminus -139.86, 178.44 59.43, 59.33 -73.59, 12.29 294.86, 96.09 -62.88, -23.79 in-in in 8.3438 Saltbr-in 2.7159 HRD-in -76.12, -45.4 67.85, -8.25 in-in-in SNCiii in-in ActLoopNT-in 2.9057 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -58.57, 128.0 APE9-dihe-na 142.75, 179.47 APE8-dihe-in -91.29, 123.75 APE8-rot-in 303.6 APE67-dihe-in -72.46, -18.07 -52.04, -36.41 APE12-dist-in 11.8654 APE11-dist-in 11.0148 APE10-dist-in 6.6475 APE9-dist-in 3.6995 None None None AF2 -1.0 1.0 1.0 A 281.0 281.0 0 30 30 0 [[21, 285]] 1.0 AF-Q9Y572-K3 TKL_RIPK3_HUMAN TKL 7.5e-66 228.3 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 7MX3B Q9Y572 12 309 518.0 ZOV:401 Type1 Inactive DFGin 6.5416 14.2613 BLAminus -142.24, -163.59 59.46, 56.29 -87.14, 32.54 292.99, 86.32 -63.8, -63.45 in-out in 8.2134 Saltbr-out 3.8841 HRD-in -71.92, -42.98 73.44, -14.04 out-in-none SNCoin in-none ActLoopNT-in 2.9397 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 174.97 APE8-rot-in 306.5 APE67-dihe-in -71.82, -40.75 -58.31, -39.26 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C3S,C110A None None XRAY 3.23 0.244 0.285 B 319.0 269.0 29 30 14 16 [[21, 285]] 1.0 7mx3 TKL_RIPK3_HUMAN TKL 7.4e-66 228.4 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 9LFUA Q9Y572 5 308 518.0 A1D97:401 Type1.5_Back Inactive DFGin 5.9961 13.6864 BLBplus -135.94, 163.32 62.81, 12.82 -63.97, 140.04 54.41, 91.52 80.44, -7.15 out-out out 16.21 Saltbr-out 17.0199 HRD-in -75.3, -56.71 75.7, -2.94 out-out-none SNCoon out-none ActLoopNT-out 6.7926 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -51.02 APE8-rot-in 298.84 APE67-dihe-in -66.45, -10.27 -90.56, 12.65 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C3S,C110A None None XRAY 2.93 0.261 0.319 A 346.0 284.0 20 30 18 12 [[21, 285]] 1.0 9lfu TKL_RIPK3_HUMAN TKL 9.8e-66 228.1 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 9LFUB Q9Y572 5 309 518.0 A1D97:401 Type1.5_Back Inactive DFGin 5.8067 13.6466 BLBplus -133.71, 159.3 64.19, 14.67 -64.66, 136.35 58.15, 93.86 79.55, -9.57 out-out out 16.2477 Saltbr-out 17.2752 HRD-in -84.97, -58.34 80.02, -12.81 out-out-out SNCooo out-out ActLoopNT-out 6.7265 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -86.85 APE8-rot-out 57.93 APE67-dihe-in -57.35, -12.11 -95.41, 2.78 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C3S,C110A None None XRAY 2.93 0.261 0.319 B 346.0 286.0 19 30 16 14 [[21, 285]] 1.0 9lfu TKL_RIPK3_HUMAN TKL 9.8e-66 228.1 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 7MONB Q9Y572 5 311 518.0 ZL1:401 Type1.5_Front Inactive DFGin 5.3187 12.8984 BLBplus -139.6, 164.18 56.61, 37.55 -80.29, 166.6 34.44, 92.89 79.72, -103.63 out-out out 11.6483 Saltbr-out 7.4128 HRD-in -76.18, -40.34 61.78, -4.08 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na 97.81, 14.44 APE9-dihe-na -63.58, 158.11 APE8-dihe-out -64.13, -29.56 APE8-rot-in 301.21 APE67-dihe-in -66.2, -17.44 -59.33, -40.24 APE12-dist-out 18.6459 APE11-dist-out 21.3159 APE10-dist-out 17.0423 APE9-dist-out 10.554 C3S,C110A TPO224,SEP227 TPO224,SEP227 XRAY 2.23 0.212 0.26 B 316.0 285.0 22 30 18 12 [[21, 285]] 1.0 7mon TKL_RIPK3_HUMAN TKL 7.2e-66 228.4 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 7MX3A Q9Y572 12 314 518.0 ZOV:401 Type1.5_Back None DFGin 6.2221 13.9088 BLAminus -152.35, -176.12 58.98, 65.68 -88.59, 21.74 285.92, 83.22 -75.2, -29.2 in-in in 7.9672 Saltbr-in 2.917 HRD-in -70.69, -48.21 67.95, 8.04 in-in-none SNCiin in-none ActLoopNT-in 3.2018 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -69.66, -25.03 999.0, -33.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C3S,C110A None None XRAY 3.23 0.244 0.285 A 319.0 292.0 11 30 20 10 [[21, 285]] 1.0 7mx3 TKL_RIPK3_HUMAN TKL 7.4e-66 228.4 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 7MX3C Q9Y572 9 311 518.0 ZOV:401 Type1.5_Back None DFGin 6.3242 14.4086 BLAminus -144.06, -179.33 56.59, 66.53 -89.63, 30.65 289.6, 92.66 -94.37, -38.42 in-in in 7.3677 Saltbr-in 3.19 HRD-in -62.63, -60.0 65.83, 13.04 in-in-none SNCiin in-none ActLoopNT-in 3.1544 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -60.63, -27.61 999.0, -44.75 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C3S,C110A None None XRAY 3.23 0.244 0.285 C 319.0 285.0 18 30 20 10 [[21, 285]] 1.0 7mx3 TKL_RIPK3_HUMAN TKL 7.4e-66 228.4 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 7MX3D Q9Y572 12 311 518.0 ZOV:401 Type1.5_Back None DFGin 6.1579 13.9338 BLAminus -152.67, -168.91 60.99, 69.08 -93.05, 21.87 286.54, 121.22 -73.96, -39.13 in-in in 8.1149 Saltbr-in 3.2288 HRD-in -81.46, -31.71 66.32, -56.05 in-in-none SNCiin in-none ActLoopNT-in 2.9385 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 153.09 APE8-rot-in 303.22 APE67-dihe-in -61.12, -38.55 -55.88, -51.2 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C3S,C110A None None XRAY 3.23 0.244 0.285 D 319.0 280.0 19 30 16 14 [[21, 285]] 1.0 7mx3 TKL_RIPK3_HUMAN TKL 7.4e-66 228.4 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3

TKL_RIPK3 (Receptor-interacting serine/threonine-protein kinase 3)

Total number of chains: 39
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 24 61.5% AF-Q9Y572-K1A
DFGin BLBplus 5 12.8% 4M69A
DFGin None 5 12.8% 9LFVA
DFGout None 5 12.8% 6OKOA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
RIPK3 RIPK3_HUMAN AF-Q9Y572-K1A Q9Y572 13 293 518.0 No_ligand No_ligand Active DFGin 6.1841 14.1071 BLAminus -136.64, 175.02 56.98, 73.57 -88.11, 18.5 298.3, 99.24 -61.96, -29.73 in-in in 8.2485 Saltbr-in 2.6925 HRD-in -72.03, -44.39 65.31, -2.99 in-in-in SNCiii in-in ActLoopNT-in 3.0657 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -86.86, 138.33 APE9-dihe-na 114.87, 169.56 APE8-dihe-in -80.98, 116.64 APE8-rot-in 302.32 APE67-dihe-in -59.85, -33.44 -51.1, -38.34 APE12-dist-in 12.498 APE11-dist-in 11.5437 APE10-dist-in 6.9311 APE9-dist-in 3.6454 None None None AF2 -1.0 1.0 1.0 A 281.0 281.0 0 30 30 0 [[21, 285]] 1.0 AF-Q9Y572-K1 Homo sapiens TKL_RIPK3_HUMAN TKL 7.5e-66 228.3 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_HUMAN AF-Q9Y572-K3A Q9Y572 13 293 518.0 No_ligand No_ligand Active DFGin 6.145 14.1327 BLAminus -139.86, 178.44 59.43, 59.33 -73.59, 12.29 294.86, 96.09 -62.88, -23.79 in-in in 8.3438 Saltbr-in 2.7159 HRD-in -76.12, -45.4 67.85, -8.25 in-in-in SNCiii in-in ActLoopNT-in 2.9057 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -58.57, 128.0 APE9-dihe-na 142.75, 179.47 APE8-dihe-in -91.29, 123.75 APE8-rot-in 303.6 APE67-dihe-in -72.46, -18.07 -52.04, -36.41 APE12-dist-in 11.8654 APE11-dist-in 11.0148 APE10-dist-in 6.6475 APE9-dist-in 3.6995 None None None AF2 -1.0 1.0 1.0 A 281.0 281.0 0 30 30 0 [[21, 285]] 1.0 AF-Q9Y572-K3 Homo sapiens TKL_RIPK3_HUMAN TKL 7.5e-66 228.3 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_HUMAN 7MX3B Q9Y572 12 309 518.0 ZOV:401 Type1 Inactive DFGin 6.5416 14.2613 BLAminus -142.24, -163.59 59.46, 56.29 -87.14, 32.54 292.99, 86.32 -63.8, -63.45 in-out in 8.2134 Saltbr-out 3.8841 HRD-in -71.92, -42.98 73.44, -14.04 out-in-none SNCoin in-none ActLoopNT-in 2.9397 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 174.97 APE8-rot-in 306.5 APE67-dihe-in -71.82, -40.75 -58.31, -39.26 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C3S,C110A None None XRAY 3.23 0.244 0.285 B 319.0 269.0 29 30 14 16 [[21, 285]] 1.0 7mx3 Homo sapiens TKL_RIPK3_HUMAN TKL 7.4e-66 228.4 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_HUMAN 9LFUA Q9Y572 5 308 518.0 A1D97:401 Type1.5_Back Inactive DFGin 5.9961 13.6864 BLBplus -135.94, 163.32 62.81, 12.82 -63.97, 140.04 54.41, 91.52 80.44, -7.15 out-out out 16.21 Saltbr-out 17.0199 HRD-in -75.3, -56.71 75.7, -2.94 out-out-none SNCoon out-none ActLoopNT-out 6.7926 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -51.02 APE8-rot-in 298.84 APE67-dihe-in -66.45, -10.27 -90.56, 12.65 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C3S,C110A None None XRAY 2.93 0.261 0.319 A 346.0 284.0 20 30 18 12 [[21, 285]] 1.0 9lfu Homo sapiens TKL_RIPK3_HUMAN TKL 9.8e-66 228.1 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_HUMAN 9LFUB Q9Y572 5 309 518.0 A1D97:401 Type1.5_Back Inactive DFGin 5.8067 13.6466 BLBplus -133.71, 159.3 64.19, 14.67 -64.66, 136.35 58.15, 93.86 79.55, -9.57 out-out out 16.2477 Saltbr-out 17.2752 HRD-in -84.97, -58.34 80.02, -12.81 out-out-out SNCooo out-out ActLoopNT-out 6.7265 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -86.85 APE8-rot-out 57.93 APE67-dihe-in -57.35, -12.11 -95.41, 2.78 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C3S,C110A None None XRAY 2.93 0.261 0.319 B 346.0 286.0 19 30 16 14 [[21, 285]] 1.0 9lfu Homo sapiens TKL_RIPK3_HUMAN TKL 9.8e-66 228.1 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_HUMAN 7MONB Q9Y572 5 311 518.0 ZL1:401 Type1.5_Front Inactive DFGin 5.3187 12.8984 BLBplus -139.6, 164.18 56.61, 37.55 -80.29, 166.6 34.44, 92.89 79.72, -103.63 out-out out 11.6483 Saltbr-out 7.4128 HRD-in -76.18, -40.34 61.78, -4.08 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na 97.81, 14.44 APE9-dihe-na -63.58, 158.11 APE8-dihe-out -64.13, -29.56 APE8-rot-in 301.21 APE67-dihe-in -66.2, -17.44 -59.33, -40.24 APE12-dist-out 18.6459 APE11-dist-out 21.3159 APE10-dist-out 17.0423 APE9-dist-out 10.554 C3S,C110A TPO224,SEP227 TPO224,SEP227 XRAY 2.23 0.212 0.26 B 316.0 285.0 22 30 18 12 [[21, 285]] 1.0 7mon Homo sapiens TKL_RIPK3_HUMAN TKL 7.2e-66 228.4 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_HUMAN 7MX3A Q9Y572 12 314 518.0 ZOV:401 Type1.5_Back None DFGin 6.2221 13.9088 BLAminus -152.35, -176.12 58.98, 65.68 -88.59, 21.74 285.92, 83.22 -75.2, -29.2 in-in in 7.9672 Saltbr-in 2.917 HRD-in -70.69, -48.21 67.95, 8.04 in-in-none SNCiin in-none ActLoopNT-in 3.2018 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -69.66, -25.03 999.0, -33.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C3S,C110A None None XRAY 3.23 0.244 0.285 A 319.0 292.0 11 30 20 10 [[21, 285]] 1.0 7mx3 Homo sapiens TKL_RIPK3_HUMAN TKL 7.4e-66 228.4 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_HUMAN 7MX3C Q9Y572 9 311 518.0 ZOV:401 Type1.5_Back None DFGin 6.3242 14.4086 BLAminus -144.06, -179.33 56.59, 66.53 -89.63, 30.65 289.6, 92.66 -94.37, -38.42 in-in in 7.3677 Saltbr-in 3.19 HRD-in -62.63, -60.0 65.83, 13.04 in-in-none SNCiin in-none ActLoopNT-in 3.1544 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -60.63, -27.61 999.0, -44.75 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C3S,C110A None None XRAY 3.23 0.244 0.285 C 319.0 285.0 18 30 20 10 [[21, 285]] 1.0 7mx3 Homo sapiens TKL_RIPK3_HUMAN TKL 7.4e-66 228.4 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_HUMAN 7MX3D Q9Y572 12 311 518.0 ZOV:401 Type1.5_Back None DFGin 6.1579 13.9338 BLAminus -152.67, -168.91 60.99, 69.08 -93.05, 21.87 286.54, 121.22 -73.96, -39.13 in-in in 8.1149 Saltbr-in 3.2288 HRD-in -81.46, -31.71 66.32, -56.05 in-in-none SNCiin in-none ActLoopNT-in 2.9385 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 153.09 APE8-rot-in 303.22 APE67-dihe-in -61.12, -38.55 -55.88, -51.2 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C3S,C110A None None XRAY 3.23 0.244 0.285 D 319.0 280.0 19 30 16 14 [[21, 285]] 1.0 7mx3 Homo sapiens TKL_RIPK3_HUMAN TKL 7.4e-66 228.4 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 4M66A Q9QZL0 15 312 486.0 No_ligand No_ligand Inactive DFGin 6.0551 13.8586 BLAminus -141.67, 175.97 66.14, 79.95 -103.85, 30.15 301.98, 92.84 -68.28, -27.67 in-in in 8.6325 Saltbr-in 2.7517 HRD-in -64.88, -51.98 74.08, -8.59 in-in-out SNCiio in-out ActLoopNT-in 2.7966 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -54.85 APE8-dihe-out -46.37, -3.77 APE8-rot-out 175.43 APE67-dihe-in -70.4, -20.56 -55.19, -35.54 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.9844 C111A None None XRAY 2.401 0.217 0.258 A 325.0 268.0 30 34 19 15 [[20, 290]] 1.0 4m66 Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IX1B Q9QZL0 15 313 486.0 PP2:60401 Type1 Inactive DFGin 6.1666 14.3523 BLAminus -148.46, 177.74 57.68, 87.36 -104.16, 25.73 298.93, 91.95 -67.83, -27.46 in-in in 8.1568 Saltbr-in 2.678 HRD-in -72.53, -47.36 68.74, 3.0 in-in-out SNCiio in-out ActLoopNT-in 2.805 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -77.43 APE8-rot-out 57.1 APE67-dihe-in -61.06, -23.36 -77.17, -1.46 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.31 0.221 0.255 B 325.0 255.0 44 34 16 18 [[20, 290]] 1.0 9ix1 Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IWWB Q9QZL0 13 313 486.0 A1D96:401 Type1.5_Back Inactive DFGin 5.9926 13.5513 BLAminus -143.56, 174.68 61.93, 81.26 -97.31, 23.35 302.29, 97.52 -69.97, -24.78 in-in in 8.395 Saltbr-in 2.8944 HRD-in -65.13, -51.7 74.4, -3.35 in-in-out SNCiio in-out ActLoopNT-in 2.7112 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -147.97, -2.69 APE9-dihe-na -82.83, -170.1 APE8-dihe-in -66.65, 153.26 APE8-rot-out 178.53 APE67-dihe-in -65.76, -22.0 -107.76, 6.47 APE12-dist-out 6.0988 APE11-dist-out 7.592 APE10-dist-out 11.2487 APE9-dist-out 9.921 None None None XRAY 1.93 0.183 0.209 B 325.0 274.0 27 34 20 14 [[20, 290]] 1.0 9iww Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IWZB Q9QZL0 14 313 486.0 ZOV:401 Type1.5_Back Inactive DFGin 5.9966 13.3046 BLAminus -144.47, 173.55 62.65, 86.08 -102.43, 20.57 300.27, 99.76 -65.16, -25.91 in-in in 8.2133 Saltbr-in 2.6838 HRD-in -67.11, -51.33 74.52, -2.58 in-in-out SNCiio in-out ActLoopNT-in 2.8492 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 2.11 APE9-dihe-na -92.49, -170.4 APE8-dihe-in -66.48, 151.74 APE8-rot-out 179.71 APE67-dihe-in -61.05, -23.54 -107.82, 2.35 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 11.5094 APE9-dist-out 9.9204 None None None XRAY 1.82 0.178 0.211 B 325.0 271.0 29 34 18 16 [[20, 290]] 1.0 9iwz Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IWXB Q9QZL0 14 313 486.0 A1D96:401 Type1.5_Back Inactive DFGin 6.3753 13.8393 BLAminus -141.47, 172.49 62.47, 82.69 -97.63, 22.27 297.98, 86.87 -70.61, -24.89 in-in in 8.3904 Saltbr-in 2.9072 HRD-in -67.61, -51.07 72.36, -2.33 in-in-out SNCiio in-out ActLoopNT-in 2.8062 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 13.18 APE9-dihe-na -80.39, -173.32 APE8-dihe-in -63.1, 154.41 APE8-rot-out 170.77 APE67-dihe-in -64.75, -25.15 -109.43, 9.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 11.098 APE9-dist-out 9.8361 R69H None None XRAY 1.99 0.189 0.236 B 325.0 270.0 30 34 18 16 [[20, 290]] 1.0 9iwx Mus musculus TKL_RIPK3_MOUSE TKL 7.7e-60 208.6 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 4M69A Q9QZL0 12 312 486.0 ANP:60401 ATPlike Inactive DFGin 6.3203 13.4024 BLBplus -137.99, 167.73 62.19, 26.69 -80.85, 141.15 41.42, 94.11 79.17, -4.63 out-out out 16.1877 Saltbr-out 16.6938 HRD-in -64.86, -72.1 85.35, 0.02 out-out-out SNCooo out-out ActLoopNT-out 6.4335 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_oooo APE10-dihe-na -38.44, -35.37 APE9-dihe-na -67.82, -39.64 APE8-dihe-out -81.63, -25.9 APE8-rot-out 193.07 APE67-dihe-in -56.22, -29.66 -74.57, -26.5 APE12-dist-out 15.2297 APE11-dist-out 16.6409 APE10-dist-out 19.2359 APE9-dist-out 12.3635 None SEP184,TPO231,SEP232 SEP184,TPO231,SEP232 XRAY 2.497 0.222 0.246 A 313.0 287.0 14 34 20 14 [[20, 290]] 1.0 4m69 Mus musculus TKL_RIPK3_MOUSE TKL 7.1e-60 208.7 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9LFWA Q9QZL0 5 312 486.0 A1D97:60401 Type1.5_Back Inactive DFGin 6.5845 13.1257 BLBplus -131.15, 162.08 64.23, 14.69 -67.09, 146.1 51.36, 90.93 77.16, -15.72 out-out out 15.9782 Saltbr-out 17.1555 HRD-in -70.85, -60.94 79.59, -9.5 out-out-out SNCooo out-out ActLoopNT-out 6.3401 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 156.06 APE8-rot-out 186.0 APE67-dihe-in -61.62, -27.57 -97.1, 3.32 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 R69H None None XRAY 1.59 0.204 0.238 A 325.0 290.0 18 34 16 18 [[20, 290]] 1.0 9lfw Mus musculus TKL_RIPK3_MOUSE TKL 7.7e-60 208.6 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IWYB Q9QZL0 15 311 486.0 A1D97:60401 Type1 Inactive DFGin 6.9678 14.0618 None -141.15, 157.34 72.96, -21.93 37.23, 42.97 300.12, 81.7 83.46, 13.22 in-none in 9.1083 Saltbr-none 999.0 HRD-in -65.47, -42.38 68.5, -9.87 none-none-none SNCnnn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, -44.45 999.0, 999.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.52 0.27 0.299 B 325.0 249.0 48 34 11 23 [[20, 290]] 1.0 9iwy Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9LFVB Q9QZL0 14 311 486.0 A1EJP:60401 Type1 Inactive DFGin 7.0186 14.0765 None -145.36, 167.9 72.34, -50.6 63.07, 38.87 298.34, 85.19 73.03, 11.82 out-out out 13.2292 Saltbr-out 11.3207 HRD-in -75.72, -32.7 64.15, -13.21 out-out-none SNCoon out-none ActLoopNT-out 11.1831 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -75.83, -8.32 999.0, 22.52 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.78 0.249 0.28 B 325.0 256.0 42 34 14 20 [[20, 290]] 1.0 9lfv Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9LFVC Q9QZL0 14 311 486.0 A1EJP:60401 Type1 Inactive DFGin 7.0132 13.8713 None -142.11, 177.11 62.46, -56.12 66.46, 24.11 299.69, 104.14 92.05, 19.19 out-none out 13.5118 Saltbr-none 999.0 HRD-in -83.63, -35.26 71.15, -28.83 none-out-none SNCnon out-none ActLoopNT-out 11.3085 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -81.07, -0.33 999.0, 20.69 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.78 0.249 0.28 C 325.0 250.0 48 34 13 21 [[20, 290]] 1.0 9lfv Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9LFVD Q9QZL0 13 311 486.0 A1EJP:60401 Type1 Inactive DFGin 7.0646 13.893 None -144.3, 176.32 70.73, -56.46 59.33, 41.69 299.17, 86.38 64.18, 23.93 out-none out 14.4012 Saltbr-none 999.0 HRD-in -78.46, -41.38 66.14, 7.65 none-out-none SNCnon out-none ActLoopNT-out 11.2611 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 148.45 APE8-rot-none 999.0 APE67-dihe-in -71.04, -19.34 -115.22, 23.97 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.78 0.249 0.28 D 325.0 255.0 44 34 14 20 [[20, 290]] 1.0 9lfv Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9LFVA Q9QZL0 13 311 486.0 A1EJO:60401,A1EJP:60402 Type1,Type1 Inactive DFGin 7.3303 14.1402 None -146.0, 165.54 71.61, -51.04 65.28, 34.98 298.07, 86.12 73.14, 14.66 out-none out 13.2609 Saltbr-none 999.0 HRD-in -73.78, -36.28 68.29, -16.9 none-out-out SNCnoo out-out ActLoopNT-out 11.3875 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 42.16 APE8-dihe-in -76.77, 175.03 APE8-rot-none 999.0 APE67-dihe-in -74.57, -14.2 -136.84, 23.77 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.0663 None None None XRAY 2.78 0.249 0.28 A 325.0 259.0 40 34 16 18 [[20, 290]] 1.0 9lfv Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 6OKOA Q9QZL0 14 311 486.0 1FN:4000 Type2 Inactive DFGout 14.6568 9.4795 None -150.96, 174.92 -144.36, 105.73 -56.39, 999.0 272.32, 88.92 999.0, 999.0 in-in in 8.2879 Saltbr-in 2.699 HRD-in -68.52, -53.05 75.17, -14.49 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -55.0 APE8-dihe-out -66.23, -6.09 APE8-rot-out 181.11 APE67-dihe-in -65.76, -28.77 -67.24, -21.39 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.2909 None None None XRAY 2.1 0.181 0.198 A 325.0 263.0 35 34 11 23 [[20, 290]] 1.0 6oko Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 6OKOB Q9QZL0 13 311 486.0 1FN:4000 Type2 Inactive DFGout 14.7969 9.688 None -145.94, 173.66 -143.61, 99.01 -60.19, 999.0 273.68, 88.75 999.0, 999.0 in-out in 8.0732 Saltbr-out 4.0529 HRD-in -68.69, -51.85 75.17, -15.43 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -65.61, -27.95 999.0, -18.66 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.1 0.181 0.198 B 325.0 261.0 38 34 9 25 [[20, 290]] 1.0 6oko Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IX2A Q9QZL0 15 311 486.0 1SU:401 Type2 Inactive DFGout 13.6069 10.0725 None -146.73, -176.51 -148.17, 113.74 -116.86, 999.0 317.74, 115.44 999.0, 999.0 in-none in 7.8993 Saltbr-none 999.0 HRD-in -70.96, -52.24 73.86, -6.08 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -168.68 APE8-rot-out 182.67 APE67-dihe-in -67.86, -14.71 -70.15, -13.52 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.39 0.23 0.276 A 325.0 259.0 38 34 10 24 [[20, 290]] 1.0 9ix2 Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IX3A Q9QZL0 15 311 486.0 A1EAA:401 Type2 Inactive DFGout 14.4616 9.3521 None -150.28, 178.71 -143.53, 103.62 -60.36, 999.0 274.25, 88.39 999.0, 999.0 in-in in 8.2525 Saltbr-in 2.8472 HRD-in -67.38, -44.32 61.93, 0.39 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 148.2 APE8-rot-out 176.48 APE67-dihe-in -68.17, -19.26 -97.75, 5.36 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.07 0.23 0.26 A 325.0 260.0 37 34 10 24 [[20, 290]] 1.0 9ix3 Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IX3B Q9QZL0 15 310 486.0 A1EAA:401 Type2 Inactive DFGout 14.445 9.0864 None -149.14, -178.68 -147.64, 102.25 -63.03, 999.0 274.85, 88.05 999.0, 999.0 in-in in 8.2708 Saltbr-in 3.3272 HRD-in -74.32, -44.8 71.29, -11.12 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -73.16, -8.52 999.0, -9.9 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.07 0.23 0.26 B 325.0 253.0 43 34 9 25 [[20, 290]] 1.0 9ix3 Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 4M66B Q9QZL0 14 313 486.0 No_ligand No_ligand None DFGin 6.2569 13.9059 BLAminus -131.04, 173.42 61.1, 97.0 -115.48, 32.44 299.35, 93.88 -64.23, -38.27 in-in in 8.4292 Saltbr-in 2.3956 HRD-in -76.55, -48.31 73.84, -8.87 in-in-none SNCiin in-none ActLoopNT-in 2.4897 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -70.87, -4.86 999.0, -21.9 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C111A None None XRAY 2.401 0.217 0.258 B 325.0 265.0 35 34 15 19 [[20, 290]] 1.0 4m66 Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IX2B Q9QZL0 13 313 486.0 No_ligand No_ligand None DFGin 6.3296 13.8594 BLAminus -148.46, -178.51 60.6, 72.26 -92.16, 23.07 300.89, 97.28 -69.06, -26.68 in-in in 8.2525 Saltbr-in 2.6873 HRD-in -69.09, -48.01 69.12, -1.67 in-in-none SNCiin in-none ActLoopNT-in 2.7741 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -51.27 APE8-rot-in 299.69 APE67-dihe-in -70.84, -21.22 -92.23, 4.03 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.39 0.23 0.276 B 325.0 264.0 37 34 15 19 [[20, 290]] 1.0 9ix2 Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IWYA Q9QZL0 15 311 486.0 A1D97:60401 Type1 None DFGin 7.3813 13.3146 BLAminus -145.3, 163.78 57.87, 69.65 -81.11, 58.68 314.75, 92.73 105.23, 999.0 none-none none 999.0 Saltbr-none 999.0 HRD-in -67.94, -45.69 67.4, -3.27 none-none-none SNCnnn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, -54.74 999.0, 999.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.52 0.27 0.299 A 325.0 243.0 54 34 9 25 [[20, 290]] 1.0 9iwy Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IX0A Q9QZL0 15 312 486.0 A1D99:401 Type1 None DFGin 6.1745 14.0314 BLAminus -143.29, 171.72 60.25, 76.29 -91.31, 27.47 299.18, 101.06 -70.53, -25.92 in-in in 8.5076 Saltbr-in 2.7566 HRD-in -63.18, -53.03 70.09, 0.01 in-in-none SNCiin in-none ActLoopNT-in 2.7289 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -148.23 APE8-dihe-in -50.23, 128.69 APE8-rot-in 297.82 APE67-dihe-in -60.6, -26.4 -69.61, -32.64 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 4.5835 None None None XRAY 2.1 0.205 0.243 A 325.0 269.0 29 34 17 17 [[20, 290]] 1.0 9ix0 Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IX0B Q9QZL0 13 311 486.0 A1D99:401 Type1 None DFGin 6.254 13.9047 BLAminus -148.35, -179.19 58.25, 77.83 -96.97, 28.2 308.45, 66.53 -68.51, -30.59 in-in in 8.662 Saltbr-in 3.0426 HRD-in -69.9, -51.03 76.13, -3.93 in-in-none SNCiin in-none ActLoopNT-in 2.7278 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -72.8 APE8-rot-none 999.0 APE67-dihe-in -63.77, -19.86 -71.87, -10.81 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.1 0.205 0.243 B 325.0 255.0 44 34 15 19 [[20, 290]] 1.0 9ix0 Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IX1A Q9QZL0 15 313 486.0 PP2:60401 Type1 None DFGin 5.9127 14.3858 BLAminus -149.4, 179.25 53.78, 84.76 -98.68, 28.86 296.35, 93.86 -68.88, -29.86 in-in in 8.49 Saltbr-in 2.8197 HRD-in -73.45, -52.59 70.92, 5.37 in-in-none SNCiin in-none ActLoopNT-in 2.8625 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -64.32, -23.19 999.0, 1.25 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.31 0.221 0.255 A 325.0 268.0 31 34 15 19 [[20, 290]] 1.0 9ix1 Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9LVGA Q9QZL0 14 312 486.0 LKR:401 Type1 None DFGin 5.9935 13.8633 BLAminus -143.57, 178.7 54.72, 82.38 -98.67, 31.08 302.44, 93.08 -71.32, -23.61 in-in in 8.5029 Saltbr-in 2.5335 HRD-in -71.75, -46.38 68.0, 5.54 in-in-none SNCiin in-none ActLoopNT-in 2.8404 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -47.4 APE8-rot-none 999.0 APE67-dihe-in -65.94, -24.52 -63.59, -34.8 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.03 0.218 0.236 A 325.0 268.0 31 34 16 18 [[20, 290]] 1.0 9lvg Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9LVGB Q9QZL0 14 311 486.0 LKR:401 Type1 None DFGin 6.0843 13.8819 BLAminus -141.96, 177.06 54.0, 89.88 -106.67, 29.11 304.14, 81.96 -69.4, -38.51 in-in in 8.5438 Saltbr-in 2.7721 HRD-in -66.91, -46.81 64.26, 6.52 in-in-none SNCiin in-none ActLoopNT-in 2.6852 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -65.66, -18.61 999.0, 5.14 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.03 0.218 0.236 B 325.0 250.0 48 34 15 19 [[20, 290]] 1.0 9lvg Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9LVHA Q9QZL0 13 312 486.0 MYF:401 Type1 None DFGin 6.2503 14.2588 BLAminus -136.98, 168.96 62.75, 89.32 -105.42, 15.63 293.79, 91.31 -62.49, -27.0 in-in in 8.3761 Saltbr-in 2.8787 HRD-in -72.81, -50.94 74.54, 2.05 in-in-none SNCiin in-none ActLoopNT-in 2.7779 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -60.25, -26.93 999.0, -1.12 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.38 0.251 0.271 A 325.0 263.0 37 34 15 19 [[20, 290]] 1.0 9lvh Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9LVHB Q9QZL0 13 312 486.0 MYF:401 Type1 None DFGin 6.1435 14.0576 BLAminus -139.36, 174.01 57.76, 83.37 -93.9, 23.89 297.93, 87.69 -58.87, -31.82 in-in in 8.5813 Saltbr-in 2.8174 HRD-in -67.48, -56.31 78.93, 2.25 in-in-none SNCiin in-none ActLoopNT-in 2.713 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 138.93 APE8-rot-in 302.42 APE67-dihe-in -61.51, -26.08 -64.96, -15.97 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.38 0.251 0.271 B 325.0 266.0 34 34 16 18 [[20, 290]] 1.0 9lvh Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IWWA Q9QZL0 13 312 486.0 A1D96:401 Type1.5_Back None DFGin 5.9859 13.4372 BLAminus -144.16, 173.05 63.98, 84.62 -101.11, 24.14 300.74, 93.26 -71.71, -26.9 in-in in 8.0882 Saltbr-in 2.8875 HRD-in -71.21, -48.68 73.29, -5.08 in-in-none SNCiin in-none ActLoopNT-in 2.7148 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnii APE10-dihe-na 999.0, -153.01 APE9-dihe-na 106.36, 163.97 APE8-dihe-in -82.15, 128.32 APE8-rot-in 297.93 APE67-dihe-in -63.89, -25.3 -71.15, -26.95 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.4108 APE9-dist-in 5.4076 None None None XRAY 1.93 0.183 0.209 A 325.0 284.0 16 34 18 16 [[20, 290]] 1.0 9iww Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IWZA Q9QZL0 13 312 486.0 ZOV:401 Type1.5_Back None DFGin 6.1672 13.3322 BLAminus -140.79, 171.83 65.16, 90.29 -104.26, 18.26 298.04, 95.08 -65.53, -28.75 in-in in 7.87 Saltbr-in 2.8577 HRD-in -70.03, -51.19 78.93, -3.69 in-in-none SNCiin in-none ActLoopNT-in 2.7668 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnii APE10-dihe-na 999.0, -29.88 APE9-dihe-na 105.08, -174.88 APE8-dihe-in -93.5, 124.97 APE8-rot-in 297.04 APE67-dihe-in -65.66, -19.22 -68.64, -29.74 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.3866 APE9-dist-in 5.623 None None None XRAY 1.82 0.178 0.211 A 325.0 285.0 15 34 19 15 [[20, 290]] 1.0 9iwz Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IWXA Q9QZL0 14 311 486.0 A1D96:401 Type1.5_Back None DFGin 6.4847 13.8364 BLAminus -139.34, 174.94 62.89, 84.12 -98.91, 17.96 292.01, 88.18 -69.55, -33.91 in-in in 8.0849 Saltbr-in 2.7899 HRD-in -70.26, -48.65 73.87, -6.66 in-in-none SNCiin in-none ActLoopNT-in 2.711 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 126.28 APE8-rot-in 301.73 APE67-dihe-in -62.28, -24.57 -68.16, -31.54 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 R69H None None XRAY 1.99 0.189 0.236 A 325.0 280.0 18 34 16 18 [[20, 290]] 1.0 9iwx Mus musculus TKL_RIPK3_MOUSE TKL 7.7e-60 208.6 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3

TKL_RIPK3 (Receptor-interacting serine/threonine-protein kinase 3)

Total number of chains: 30
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 18 60.0% 9IWZA
DFGin None 5 16.7% 9LFVA
DFGout None 5 16.7% 6OKOA
DFGin BLBplus 2 6.7% 4M69A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
RIPK3 RIPK3_MOUSE 4M66A Q9QZL0 15 312 486.0 No_ligand No_ligand Inactive DFGin 6.0551 13.8586 BLAminus -141.67, 175.97 66.14, 79.95 -103.85, 30.15 301.98, 92.84 -68.28, -27.67 in-in in 8.6325 Saltbr-in 2.7517 HRD-in -64.88, -51.98 74.08, -8.59 in-in-out SNCiio in-out ActLoopNT-in 2.7966 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -54.85 APE8-dihe-out -46.37, -3.77 APE8-rot-out 175.43 APE67-dihe-in -70.4, -20.56 -55.19, -35.54 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.9844 C111A None None XRAY 2.401 0.217 0.258 A 325.0 268.0 30 34 19 15 [[20, 290]] 1.0 4m66 Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IX1B Q9QZL0 15 313 486.0 PP2:60401 Type1 Inactive DFGin 6.1666 14.3523 BLAminus -148.46, 177.74 57.68, 87.36 -104.16, 25.73 298.93, 91.95 -67.83, -27.46 in-in in 8.1568 Saltbr-in 2.678 HRD-in -72.53, -47.36 68.74, 3.0 in-in-out SNCiio in-out ActLoopNT-in 2.805 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -77.43 APE8-rot-out 57.1 APE67-dihe-in -61.06, -23.36 -77.17, -1.46 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.31 0.221 0.255 B 325.0 255.0 44 34 16 18 [[20, 290]] 1.0 9ix1 Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IWWB Q9QZL0 13 313 486.0 A1D96:401 Type1.5_Back Inactive DFGin 5.9926 13.5513 BLAminus -143.56, 174.68 61.93, 81.26 -97.31, 23.35 302.29, 97.52 -69.97, -24.78 in-in in 8.395 Saltbr-in 2.8944 HRD-in -65.13, -51.7 74.4, -3.35 in-in-out SNCiio in-out ActLoopNT-in 2.7112 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -147.97, -2.69 APE9-dihe-na -82.83, -170.1 APE8-dihe-in -66.65, 153.26 APE8-rot-out 178.53 APE67-dihe-in -65.76, -22.0 -107.76, 6.47 APE12-dist-out 6.0988 APE11-dist-out 7.592 APE10-dist-out 11.2487 APE9-dist-out 9.921 None None None XRAY 1.93 0.183 0.209 B 325.0 274.0 27 34 20 14 [[20, 290]] 1.0 9iww Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IWZB Q9QZL0 14 313 486.0 ZOV:401 Type1.5_Back Inactive DFGin 5.9966 13.3046 BLAminus -144.47, 173.55 62.65, 86.08 -102.43, 20.57 300.27, 99.76 -65.16, -25.91 in-in in 8.2133 Saltbr-in 2.6838 HRD-in -67.11, -51.33 74.52, -2.58 in-in-out SNCiio in-out ActLoopNT-in 2.8492 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 2.11 APE9-dihe-na -92.49, -170.4 APE8-dihe-in -66.48, 151.74 APE8-rot-out 179.71 APE67-dihe-in -61.05, -23.54 -107.82, 2.35 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 11.5094 APE9-dist-out 9.9204 None None None XRAY 1.82 0.178 0.211 B 325.0 271.0 29 34 18 16 [[20, 290]] 1.0 9iwz Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IWXB Q9QZL0 14 313 486.0 A1D96:401 Type1.5_Back Inactive DFGin 6.3753 13.8393 BLAminus -141.47, 172.49 62.47, 82.69 -97.63, 22.27 297.98, 86.87 -70.61, -24.89 in-in in 8.3904 Saltbr-in 2.9072 HRD-in -67.61, -51.07 72.36, -2.33 in-in-out SNCiio in-out ActLoopNT-in 2.8062 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 13.18 APE9-dihe-na -80.39, -173.32 APE8-dihe-in -63.1, 154.41 APE8-rot-out 170.77 APE67-dihe-in -64.75, -25.15 -109.43, 9.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 11.098 APE9-dist-out 9.8361 R69H None None XRAY 1.99 0.189 0.236 B 325.0 270.0 30 34 18 16 [[20, 290]] 1.0 9iwx Mus musculus TKL_RIPK3_MOUSE TKL 7.7e-60 208.6 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 4M69A Q9QZL0 12 312 486.0 ANP:60401 ATPlike Inactive DFGin 6.3203 13.4024 BLBplus -137.99, 167.73 62.19, 26.69 -80.85, 141.15 41.42, 94.11 79.17, -4.63 out-out out 16.1877 Saltbr-out 16.6938 HRD-in -64.86, -72.1 85.35, 0.02 out-out-out SNCooo out-out ActLoopNT-out 6.4335 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_oooo APE10-dihe-na -38.44, -35.37 APE9-dihe-na -67.82, -39.64 APE8-dihe-out -81.63, -25.9 APE8-rot-out 193.07 APE67-dihe-in -56.22, -29.66 -74.57, -26.5 APE12-dist-out 15.2297 APE11-dist-out 16.6409 APE10-dist-out 19.2359 APE9-dist-out 12.3635 None SEP184,TPO231,SEP232 SEP184,TPO231,SEP232 XRAY 2.497 0.222 0.246 A 313.0 287.0 14 34 20 14 [[20, 290]] 1.0 4m69 Mus musculus TKL_RIPK3_MOUSE TKL 7.1e-60 208.7 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9LFWA Q9QZL0 5 312 486.0 A1D97:60401 Type1.5_Back Inactive DFGin 6.5845 13.1257 BLBplus -131.15, 162.08 64.23, 14.69 -67.09, 146.1 51.36, 90.93 77.16, -15.72 out-out out 15.9782 Saltbr-out 17.1555 HRD-in -70.85, -60.94 79.59, -9.5 out-out-out SNCooo out-out ActLoopNT-out 6.3401 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 156.06 APE8-rot-out 186.0 APE67-dihe-in -61.62, -27.57 -97.1, 3.32 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 R69H None None XRAY 1.59 0.204 0.238 A 325.0 290.0 18 34 16 18 [[20, 290]] 1.0 9lfw Mus musculus TKL_RIPK3_MOUSE TKL 7.7e-60 208.6 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IWYB Q9QZL0 15 311 486.0 A1D97:60401 Type1 Inactive DFGin 6.9678 14.0618 None -141.15, 157.34 72.96, -21.93 37.23, 42.97 300.12, 81.7 83.46, 13.22 in-none in 9.1083 Saltbr-none 999.0 HRD-in -65.47, -42.38 68.5, -9.87 none-none-none SNCnnn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, -44.45 999.0, 999.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.52 0.27 0.299 B 325.0 249.0 48 34 11 23 [[20, 290]] 1.0 9iwy Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9LFVB Q9QZL0 14 311 486.0 A1EJP:60401 Type1 Inactive DFGin 7.0186 14.0765 None -145.36, 167.9 72.34, -50.6 63.07, 38.87 298.34, 85.19 73.03, 11.82 out-out out 13.2292 Saltbr-out 11.3207 HRD-in -75.72, -32.7 64.15, -13.21 out-out-none SNCoon out-none ActLoopNT-out 11.1831 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -75.83, -8.32 999.0, 22.52 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.78 0.249 0.28 B 325.0 256.0 42 34 14 20 [[20, 290]] 1.0 9lfv Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9LFVC Q9QZL0 14 311 486.0 A1EJP:60401 Type1 Inactive DFGin 7.0132 13.8713 None -142.11, 177.11 62.46, -56.12 66.46, 24.11 299.69, 104.14 92.05, 19.19 out-none out 13.5118 Saltbr-none 999.0 HRD-in -83.63, -35.26 71.15, -28.83 none-out-none SNCnon out-none ActLoopNT-out 11.3085 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -81.07, -0.33 999.0, 20.69 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.78 0.249 0.28 C 325.0 250.0 48 34 13 21 [[20, 290]] 1.0 9lfv Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9LFVD Q9QZL0 13 311 486.0 A1EJP:60401 Type1 Inactive DFGin 7.0646 13.893 None -144.3, 176.32 70.73, -56.46 59.33, 41.69 299.17, 86.38 64.18, 23.93 out-none out 14.4012 Saltbr-none 999.0 HRD-in -78.46, -41.38 66.14, 7.65 none-out-none SNCnon out-none ActLoopNT-out 11.2611 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 148.45 APE8-rot-none 999.0 APE67-dihe-in -71.04, -19.34 -115.22, 23.97 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.78 0.249 0.28 D 325.0 255.0 44 34 14 20 [[20, 290]] 1.0 9lfv Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9LFVA Q9QZL0 13 311 486.0 A1EJO:60401,A1EJP:60402 Type1,Type1 Inactive DFGin 7.3303 14.1402 None -146.0, 165.54 71.61, -51.04 65.28, 34.98 298.07, 86.12 73.14, 14.66 out-none out 13.2609 Saltbr-none 999.0 HRD-in -73.78, -36.28 68.29, -16.9 none-out-out SNCnoo out-out ActLoopNT-out 11.3875 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 42.16 APE8-dihe-in -76.77, 175.03 APE8-rot-none 999.0 APE67-dihe-in -74.57, -14.2 -136.84, 23.77 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.0663 None None None XRAY 2.78 0.249 0.28 A 325.0 259.0 40 34 16 18 [[20, 290]] 1.0 9lfv Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 6OKOA Q9QZL0 14 311 486.0 1FN:4000 Type2 Inactive DFGout 14.6568 9.4795 None -150.96, 174.92 -144.36, 105.73 -56.39, 999.0 272.32, 88.92 999.0, 999.0 in-in in 8.2879 Saltbr-in 2.699 HRD-in -68.52, -53.05 75.17, -14.49 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -55.0 APE8-dihe-out -66.23, -6.09 APE8-rot-out 181.11 APE67-dihe-in -65.76, -28.77 -67.24, -21.39 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.2909 None None None XRAY 2.1 0.181 0.198 A 325.0 263.0 35 34 11 23 [[20, 290]] 1.0 6oko Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 6OKOB Q9QZL0 13 311 486.0 1FN:4000 Type2 Inactive DFGout 14.7969 9.688 None -145.94, 173.66 -143.61, 99.01 -60.19, 999.0 273.68, 88.75 999.0, 999.0 in-out in 8.0732 Saltbr-out 4.0529 HRD-in -68.69, -51.85 75.17, -15.43 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -65.61, -27.95 999.0, -18.66 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.1 0.181 0.198 B 325.0 261.0 38 34 9 25 [[20, 290]] 1.0 6oko Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IX2A Q9QZL0 15 311 486.0 1SU:401 Type2 Inactive DFGout 13.6069 10.0725 None -146.73, -176.51 -148.17, 113.74 -116.86, 999.0 317.74, 115.44 999.0, 999.0 in-none in 7.8993 Saltbr-none 999.0 HRD-in -70.96, -52.24 73.86, -6.08 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -168.68 APE8-rot-out 182.67 APE67-dihe-in -67.86, -14.71 -70.15, -13.52 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.39 0.23 0.276 A 325.0 259.0 38 34 10 24 [[20, 290]] 1.0 9ix2 Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IX3A Q9QZL0 15 311 486.0 A1EAA:401 Type2 Inactive DFGout 14.4616 9.3521 None -150.28, 178.71 -143.53, 103.62 -60.36, 999.0 274.25, 88.39 999.0, 999.0 in-in in 8.2525 Saltbr-in 2.8472 HRD-in -67.38, -44.32 61.93, 0.39 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 148.2 APE8-rot-out 176.48 APE67-dihe-in -68.17, -19.26 -97.75, 5.36 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.07 0.23 0.26 A 325.0 260.0 37 34 10 24 [[20, 290]] 1.0 9ix3 Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IX3B Q9QZL0 15 310 486.0 A1EAA:401 Type2 Inactive DFGout 14.445 9.0864 None -149.14, -178.68 -147.64, 102.25 -63.03, 999.0 274.85, 88.05 999.0, 999.0 in-in in 8.2708 Saltbr-in 3.3272 HRD-in -74.32, -44.8 71.29, -11.12 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -73.16, -8.52 999.0, -9.9 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.07 0.23 0.26 B 325.0 253.0 43 34 9 25 [[20, 290]] 1.0 9ix3 Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 4M66B Q9QZL0 14 313 486.0 No_ligand No_ligand None DFGin 6.2569 13.9059 BLAminus -131.04, 173.42 61.1, 97.0 -115.48, 32.44 299.35, 93.88 -64.23, -38.27 in-in in 8.4292 Saltbr-in 2.3956 HRD-in -76.55, -48.31 73.84, -8.87 in-in-none SNCiin in-none ActLoopNT-in 2.4897 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -70.87, -4.86 999.0, -21.9 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C111A None None XRAY 2.401 0.217 0.258 B 325.0 265.0 35 34 15 19 [[20, 290]] 1.0 4m66 Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IX2B Q9QZL0 13 313 486.0 No_ligand No_ligand None DFGin 6.3296 13.8594 BLAminus -148.46, -178.51 60.6, 72.26 -92.16, 23.07 300.89, 97.28 -69.06, -26.68 in-in in 8.2525 Saltbr-in 2.6873 HRD-in -69.09, -48.01 69.12, -1.67 in-in-none SNCiin in-none ActLoopNT-in 2.7741 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -51.27 APE8-rot-in 299.69 APE67-dihe-in -70.84, -21.22 -92.23, 4.03 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.39 0.23 0.276 B 325.0 264.0 37 34 15 19 [[20, 290]] 1.0 9ix2 Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IWYA Q9QZL0 15 311 486.0 A1D97:60401 Type1 None DFGin 7.3813 13.3146 BLAminus -145.3, 163.78 57.87, 69.65 -81.11, 58.68 314.75, 92.73 105.23, 999.0 none-none none 999.0 Saltbr-none 999.0 HRD-in -67.94, -45.69 67.4, -3.27 none-none-none SNCnnn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, -54.74 999.0, 999.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.52 0.27 0.299 A 325.0 243.0 54 34 9 25 [[20, 290]] 1.0 9iwy Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IX0A Q9QZL0 15 312 486.0 A1D99:401 Type1 None DFGin 6.1745 14.0314 BLAminus -143.29, 171.72 60.25, 76.29 -91.31, 27.47 299.18, 101.06 -70.53, -25.92 in-in in 8.5076 Saltbr-in 2.7566 HRD-in -63.18, -53.03 70.09, 0.01 in-in-none SNCiin in-none ActLoopNT-in 2.7289 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -148.23 APE8-dihe-in -50.23, 128.69 APE8-rot-in 297.82 APE67-dihe-in -60.6, -26.4 -69.61, -32.64 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 4.5835 None None None XRAY 2.1 0.205 0.243 A 325.0 269.0 29 34 17 17 [[20, 290]] 1.0 9ix0 Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IX0B Q9QZL0 13 311 486.0 A1D99:401 Type1 None DFGin 6.254 13.9047 BLAminus -148.35, -179.19 58.25, 77.83 -96.97, 28.2 308.45, 66.53 -68.51, -30.59 in-in in 8.662 Saltbr-in 3.0426 HRD-in -69.9, -51.03 76.13, -3.93 in-in-none SNCiin in-none ActLoopNT-in 2.7278 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -72.8 APE8-rot-none 999.0 APE67-dihe-in -63.77, -19.86 -71.87, -10.81 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.1 0.205 0.243 B 325.0 255.0 44 34 15 19 [[20, 290]] 1.0 9ix0 Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IX1A Q9QZL0 15 313 486.0 PP2:60401 Type1 None DFGin 5.9127 14.3858 BLAminus -149.4, 179.25 53.78, 84.76 -98.68, 28.86 296.35, 93.86 -68.88, -29.86 in-in in 8.49 Saltbr-in 2.8197 HRD-in -73.45, -52.59 70.92, 5.37 in-in-none SNCiin in-none ActLoopNT-in 2.8625 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -64.32, -23.19 999.0, 1.25 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.31 0.221 0.255 A 325.0 268.0 31 34 15 19 [[20, 290]] 1.0 9ix1 Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9LVGA Q9QZL0 14 312 486.0 LKR:401 Type1 None DFGin 5.9935 13.8633 BLAminus -143.57, 178.7 54.72, 82.38 -98.67, 31.08 302.44, 93.08 -71.32, -23.61 in-in in 8.5029 Saltbr-in 2.5335 HRD-in -71.75, -46.38 68.0, 5.54 in-in-none SNCiin in-none ActLoopNT-in 2.8404 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -47.4 APE8-rot-none 999.0 APE67-dihe-in -65.94, -24.52 -63.59, -34.8 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.03 0.218 0.236 A 325.0 268.0 31 34 16 18 [[20, 290]] 1.0 9lvg Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9LVGB Q9QZL0 14 311 486.0 LKR:401 Type1 None DFGin 6.0843 13.8819 BLAminus -141.96, 177.06 54.0, 89.88 -106.67, 29.11 304.14, 81.96 -69.4, -38.51 in-in in 8.5438 Saltbr-in 2.7721 HRD-in -66.91, -46.81 64.26, 6.52 in-in-none SNCiin in-none ActLoopNT-in 2.6852 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -65.66, -18.61 999.0, 5.14 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.03 0.218 0.236 B 325.0 250.0 48 34 15 19 [[20, 290]] 1.0 9lvg Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9LVHA Q9QZL0 13 312 486.0 MYF:401 Type1 None DFGin 6.2503 14.2588 BLAminus -136.98, 168.96 62.75, 89.32 -105.42, 15.63 293.79, 91.31 -62.49, -27.0 in-in in 8.3761 Saltbr-in 2.8787 HRD-in -72.81, -50.94 74.54, 2.05 in-in-none SNCiin in-none ActLoopNT-in 2.7779 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -60.25, -26.93 999.0, -1.12 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.38 0.251 0.271 A 325.0 263.0 37 34 15 19 [[20, 290]] 1.0 9lvh Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9LVHB Q9QZL0 13 312 486.0 MYF:401 Type1 None DFGin 6.1435 14.0576 BLAminus -139.36, 174.01 57.76, 83.37 -93.9, 23.89 297.93, 87.69 -58.87, -31.82 in-in in 8.5813 Saltbr-in 2.8174 HRD-in -67.48, -56.31 78.93, 2.25 in-in-none SNCiin in-none ActLoopNT-in 2.713 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 138.93 APE8-rot-in 302.42 APE67-dihe-in -61.51, -26.08 -64.96, -15.97 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.38 0.251 0.271 B 325.0 266.0 34 34 16 18 [[20, 290]] 1.0 9lvh Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IWWA Q9QZL0 13 312 486.0 A1D96:401 Type1.5_Back None DFGin 5.9859 13.4372 BLAminus -144.16, 173.05 63.98, 84.62 -101.11, 24.14 300.74, 93.26 -71.71, -26.9 in-in in 8.0882 Saltbr-in 2.8875 HRD-in -71.21, -48.68 73.29, -5.08 in-in-none SNCiin in-none ActLoopNT-in 2.7148 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnii APE10-dihe-na 999.0, -153.01 APE9-dihe-na 106.36, 163.97 APE8-dihe-in -82.15, 128.32 APE8-rot-in 297.93 APE67-dihe-in -63.89, -25.3 -71.15, -26.95 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.4108 APE9-dist-in 5.4076 None None None XRAY 1.93 0.183 0.209 A 325.0 284.0 16 34 18 16 [[20, 290]] 1.0 9iww Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IWZA Q9QZL0 13 312 486.0 ZOV:401 Type1.5_Back None DFGin 6.1672 13.3322 BLAminus -140.79, 171.83 65.16, 90.29 -104.26, 18.26 298.04, 95.08 -65.53, -28.75 in-in in 7.87 Saltbr-in 2.8577 HRD-in -70.03, -51.19 78.93, -3.69 in-in-none SNCiin in-none ActLoopNT-in 2.7668 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnii APE10-dihe-na 999.0, -29.88 APE9-dihe-na 105.08, -174.88 APE8-dihe-in -93.5, 124.97 APE8-rot-in 297.04 APE67-dihe-in -65.66, -19.22 -68.64, -29.74 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.3866 APE9-dist-in 5.623 None None None XRAY 1.82 0.178 0.211 A 325.0 285.0 15 34 19 15 [[20, 290]] 1.0 9iwz Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
RIPK3 RIPK3_MOUSE 9IWXA Q9QZL0 14 311 486.0 A1D96:401 Type1.5_Back None DFGin 6.4847 13.8364 BLAminus -139.34, 174.94 62.89, 84.12 -98.91, 17.96 292.01, 88.18 -69.55, -33.91 in-in in 8.0849 Saltbr-in 2.7899 HRD-in -70.26, -48.65 73.87, -6.66 in-in-none SNCiin in-none ActLoopNT-in 2.711 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 126.28 APE8-rot-in 301.73 APE67-dihe-in -62.28, -24.57 -68.16, -31.54 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 R69H None None XRAY 1.99 0.189 0.236 A 325.0 280.0 18 34 16 18 [[20, 290]] 1.0 9iwx Mus musculus TKL_RIPK3_MOUSE TKL 7.7e-60 208.6 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3